Prodrugs of nitroxyl and nitrosobenzene as cascade latentiated inhibitors of aldehyde dehydrogenase

Journal of Medicinal Chemistry

Volumn 41, Issue 15, 1998, Pages 2903-2909

  Conway, Terry T ^a   DeMaster, Eugene G ^a   Lee, Melinda J C ^b   Nagasawa, Herbert T ^a,c  

^a VA MEDICAL CENTER   (United States)

^b ST CLOUD STATE UNIVERSITY   (United States)

^c UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDE DEHYDROGENASE; N CARBOMETHYL O METHYLMETHANESULFOHYDROXAMIC ACID; NITROSOBENZENE; PRODRUG; UNCLASSIFIED DRUG;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CATALYSIS; DERIVATIZATION; DRUG ACTIVITY; DRUG EFFECT; ENZYME ACTIVITY; ENZYME INHIBITION; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE;

ACETALDEHYDE; ALDEHYDE DEHYDROGENASE; ANIMALS; ENZYME INHIBITORS; ETHANOL; HYDROXAMIC ACIDS; LIVER; MALE; NITROGEN OXIDES; NITROSO COMPOUNDS; PRODRUGS; RATS; RATS, SPRAGUE-DAWLEY; SULFONAMIDES; SWINE; YEASTS;

EID: 0031852127     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm980200+     Document Type: Article

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