Allelotype analysis of early colorectal cancers with lymph node metastasis

International Journal of Cancer

Volumn 79, Issue 4, 1998, Pages 418-423

  Arai, Takehiro ^a   Akiyama, Yoshimitsu ^a   Yamamura, Akihiko ^b   Hosoi, Tozo ^b   Shibata, Toshikatsu ^c   Saitoh, Kiyoshi ^d   Okabe, Satoshi ^a   Yuasa, Yasuhito ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b Tokyo Metropolitan Tama Cancer Detection Center   (Japan)

^c Tsuchiura Kyodo Hospital   (Japan)

^d NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P53;

ADULT; AGED; ALLELE; ARTICLE; CANCER STAGING; CHROMOSOME 18Q; CHROMOSOME 8P; CLINICAL ARTICLE; COLON CARCINOGENESIS; COLORECTAL CANCER; FEMALE; HETEROZYGOSITY LOSS; HUMAN; HUMAN TISSUE; LYMPH NODE METASTASIS; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RISK FACTOR;

ADULT; AGED; ALLELES; CARCINOMA; CHROMOSOME DELETION; COLORECTAL NEOPLASMS; FEMALE; HUMANS; LOSS OF HETEROZYGOSITY; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0031852088     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0215(19980821)79:4<418::AID-IJC18>3.0.CO;2-0     Document Type: Article

References (21)

1. BERTORELLE, R., ESPOSITO, G., MISTRO, A.D., BELLUCO, C., NITTI, D., LISE, M. and CHIECO-BLANCHI, L., Association of p53 gene and protein alterations with metastasis in colorectal cancer. Am. J. Surg. Pathol., 19, 463-471 (1995).
2. EPPERT, K. and 12 OTHERS, MADR2 maps to 18q21 and encodes a TGFβ-regulated MAD-related protein that is functionally mutated in colorectal carcinoma. Cell, 86, 543-552 (1996).
3. FEARON, E.R. and VOGELSTEIN, B., A genetic model for colorectal tumorigenesis. Cell, 61, 759-767 (1990).
4. FUJIWARA, Y., OHATA, H., KUROKI, T., KOYAMA, K., TSUCHIYA, E., MONDEN, M. and NAKAMURA, Y., Isolation of a candidate tumor suppressor gene on chromosome 8p21.3-p22 that is homologous to an extracellular domain of the PDGF receptor beta gene. Oncogene, 10, 891-895 (1995).
5. GOELZ, S.E., HAMILTON, S.R. and VOGELSTEIN, B., Purification of DNA from formaldehyde fixed and paraffin embedded human tissue. Biochem. biophys. Res. Comm., 130, 118-126 (1985).
6. GUSTAFSON, C.E., WILSON, P.J., LUKEIS, R., BAKER, E., WOOLLATT, E., ANNAB, L., HAWKE, L., BARRETT, J.C. and CHENEVIX-TRENCH, G., Functional evidence for a colorectal cancer tumor suppressor gene at chromosome 8p22-23 by monochromosome transfer. Cancer Res., 56, 5238-5245 (1996).
7. HAHN, S.A., SCHUTTE, M., HOQUE, A.T.M.S, MOSKALUK, C.A., DA COSTA, L.T., ROZENBLUM, E., WEINSTEIN, C.L., FISCHER, A., YEO, C.J., HRUBAN, R.H. and KERN, S.E., DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1. Science, 271, 350-353 (1996).
8. IINO, H., FUKAYAMA, M., MAEDA, Y., KOIKE, M., MORI, T., TAKAHASHI, T., KIKUCHI-YANOSHITA, R., MIYAKI, M., MIZUNO, S. and WATANABE, S., Molecular genetics for clinical management of colorectal carcinoma. Cancer, 73, 1324-1331 (1994).
9. JAPANESE RESEARCH SOCIETY FOR CANCER OF THE COLON AND RECTUM, General rules for clinical and pathological studies on cancer of the colon, rectum and anus. Jpn. J. Surg., 13, 557-598 (1983).
10. KIKUCHI-YANOSHITA, R. and 13 OTHERS, Genetic changes of both p53 alleles associated with the conversion from colorectal adenoma to early carcinoma in familial adenomatous polyposis and non familial adenomatous polyposis patients. Cancer Res., 52, 3965-3971 (1992).
11. KITAMURA, K., TANIGUCHI, H., YAMAGUCHI, T., SAWAI, K. and TAKAHASHI, T., Clinical outcome of surgical treatment for invasive early colorectal cancer in Japan. Hepato-Gastroenterology, 44, 108-115 (1997).
12. NIVATVONGS, S., ROJANASAKUL, A., REIMAN, H.M., DOZOIS, R., WOLFF, B.G., PEMBERTON, J.H., BEART, R.W.JR. and JACQUES, L.F., The risk of lymph node metastasis in colorectal polyps with invasive adenocarcinoma. Dis. Colon Rectum, 34, 323-328 (1991).
13. PRAML, C., FINKE, L.H., HERFARTH, C., SCHLAG, P., SCHWAB, M.. and AMLER, L., Deletion mapping defines different regions in 1p34.2-pter that may harbor genetic information related to human colorectal cancer. Oncogene, 11, 1357-1362 (1995).
14. SOBIN, L.H. and WITTEKIND, C.H., UICC TNM classification of malignant tumours. pp. 66-69, 5th ed., Springer, Berlin (1997).
15. TAKAGI, Y., KOHMURA, H., FUTAMURA, M., KIDA, H., TANEMURA, H., SHIMOKAWA, K. and SAJI, S,. Somatic alterations of the DPC4 gene in human colorectal cancers in vivo. Gastroenterology, 111, 1369-1372 (1996).
16. TANAKA, K., KIKUCHI-YANOSHITA, R., MURAOKA, M., KONISHI, M., OSHIMURA, M. and MIYAKI, M., Suppression of tumorigenicity and invasiveness of colon carcinoma cells by introduction of normal chromosome 8p12-pter. Oncogene, 12, 405-410 (1996).
17. THORSTENSEN, L., QVIST, H., NESLAND, J.M., GIERCKSKY, K.-E. and LOTHE, R.A., Allelotype profiles of local recurrences and distant metastases from colorectal-cancer patients. Int. J. Cancer, 69, 452-456 (1996).
18. VOGELSTEIN, B., FEARON, E.R., KERN, S.E., HAMILTON, S.R., PREISINGER, A.C., NAKAMURA, Y. and WHITE, R., Allelotype of colorectal carcinomas. Science, 244, 207-210 (1989).
19. YAMAGUCHI, A., KUROSAKA, Y., FUSHIDA, S., KANNO, M., YONEMURA, Y., MIWA, K. and MIYAZAKI, I., Expression of p53 protein in colorectal cancer and its relationship to short-term prognosis. Cancer, 70, 2778-2784 (1992).
20. YANA, I., KURAHASHI, H., NAKAMORI, S., KAMEYAMA, M., NAKAMURA, T., TAKAMI, M., MORI, T., TAKAI, S. and NISHISHO, I., Frequent loss of heterozygosity at telomeric loci on 22q in sporadic colorectal cancers. Int. J. Cancer, 60, 174-177 (1995).
21. YOUNG, J., LEGGETT, B., WARD, M., THOMAS, L., BUTTENSHAW, R., SEARLE, J. and CHENEVIX-TRENCH, G., Frequent loss of heterozygosity on chromosome 14 occurs in advanced colorectal carcinomas. Oncogene, 8, 671-675 (1993).