Enlargement of the juxtaglomerular apparatus in insulin-dependent diabetes mellitus patients with microalbuminuria

Virchows Archiv

Volumn 433, Issue 1, 1998, Pages 63-67

  Gulmann, Christian ^a   Rudberg, Susanne ^b   Nyberg, Gudrun ^c   Østerby, Ruth ^a  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

^b KAROLINSKA INSTITUTE   (Sweden)

^c SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Diabetic glomerulopathy; IDDM; Juxtaglomerular apparatus pathology; Microalbuminuria; Stereology

Indexed keywords

ALBUMIN;

ADOLESCENT; ADULT; ARTERIOLE; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; INSULIN DEPENDENT DIABETES MELLITUS; JUXTAGLOMERULAR APPARATUS; KIDNEY BIOPSY; KIDNEY HYPERTROPHY; MACULA DENSA; MALE; MICROALBUMINURIA; MICROSCOPY; PRIORITY JOURNAL;

ADOLESCENT; ADULT; ALBUMINURIA; DIABETES MELLITUS, TYPE 1; DIABETIC NEPHROPATHIES; FEMALE; HUMANS; JUXTAGLOMERULAR APPARATUS; MALE;

EID: 0031848405     PISSN: 09456317     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004280050217     Document Type: Article

References (26)

1. Andersen S, Jung FF, Ingelfinger JR (1993) Renal renin-angiotensin system in diabetes: functional, immunohistochemical, and molecular biological correlations. Am J Physiol 265: F477-F486
2. Bader H, Meyer DS (1977) The size of the juxtaglomerular apparatus in diabetic glomerulosclerosis and its correlation with arteriosclerosis and arterial hypertension: a morphometric light microscopic study on human renal biopsies. Clin Nephrol 8:308-311
3. Bjorck S (1990) The renin angiotensin system in diabetes mellitus. A physiological and therapeutic study. Scand J Urol Nephrol Suppl 126:1-51
4. Blantz RC, Peterson OW, Gushwa L, Tucker BJ (1982) Effect of modest hyperglycemia on tubuloglomerular feedback activity. Kidney Int Suppl 12:S206-S212
5. Christlieb AR (1976) Renin-angiotensin-aldosterone system in diabetes mellitus. Diabetes 25:820-825
6. Gundersen HJ, Bendtsen TF, Korbo L, Marcussen N, Mollar A, Nielsen K, Nyengaard JR, Pakkenberg B, Sorensen FB, Vesterby A (1988) Some new, simple and efficient stereological methods and their use in pathological research and diagnosis. APMIS 96:379-394
7. Hsueh WA, Anderson PW (1993) Systemic hypertension and the renin-angiotensin system in diabetic vascular complications. Am J Cardiol 72:14H-21H
8. Inagami T, Mizuno K, Naruse K, Okamura T, Kawamura M (1990) Intracellular formation and release of angiotensins from juxtaglomerular cells. Kidney Int Suppl 30:S33-S37
9. Jensen PK, Kristensen KS, Rasch R, Persson AEG (1988) Decreased sensitivity of the tubuloglomerular feedback mechanism in experimental diabetic rats. In: Persson AEG, Boberg U (eds) The juxtaglomerular apparatus. Elsevier Science, Amsterdam, pp 333-338
10. Kimura K, Tojo A, Nanba S, Matsuoka H, Sugimoto T (1990) Morphometric analysis of arteriolar diameters in experimental nephropathies: application of microvascular casts. Virchows Arch [A] 417:319-323
11. Lane PH, Steffes MW, Mauer SM (1992) Estimation of glomerular volume: a comparison of four methods. Kidney Int 41: 1085-1089
12. Ohishi K, Okwueze MI, Vari RC, Carmines PK (1994) Juxtamedullary microsvascular dysfunction during the hyperfiltration stage of diabetes mellitus. Am J Physiol 267:F99-105
13. Olivetti G, Anversa P, Rigamonti W, Vitali-Mazza L, Loud AV (1977) Morphometry of the renal corpuscle during normal postnatal growth and compensatory hypertrophy: a light microscope study. J Cell Biol 75:573-585
14. Osterby R (1993) Renal pathology in diabetes mellitus. Curr Opin Nephrol Hypertens 2:475-483
15. Osterby R (1995) Research methodologies related to renal complications: structural changes. In: Mogensen CE, Standl E (eds) Research methodologies in human diabetes. 2. Walter de Gruyter, Berlin New York, pp 289-309
16. Osterby R, Gundersen HJ (1975) Glomerular size and structure in diabetes mellitus. I. Early abnormalities. Diabetologia 11:225-229
17. Osterby R, Asplund J, Bangstad HJ, Nyberg G, Rudberg S, Viberti G, Walker JD (1997) Glomerular volume and the vascular pole area in patients with insulin-dependent diabetes mellitus. Virchows Arch 431:351-357
18. Paulsen EP, Burke BA, Vernier RL, Mallare MJ, Innes DJJ, Sturgill BC (1994) Juxtaglomerular body abnormalities in youth-onset diabetic subjects. Kidney Int 45:1132-1139
19. Rasch R, Holck P (1988) Ultrastructure of the macula densa in streptozotocin diabetic rats. Lab Invest 59:666-672
20. Sorensen FH (1972) Quantitative studies of the renal corpuscles. I. Intraglomerular, interglomerular and interfocal variation in the normal kidney. Acta Pathol Microbiol Scand [A] 80:115-124
21. Taugner R, Hackenthal E (1989) The juxtaglomerular apparatus, 1st edn. Springer, Berlin Heidelberg New York, pp 20-25
22. Taugner R, Buhrle CP, Hackenthal E, Mannek E, Nobiling R (1984) Morphology of the juxtaglomerular apparatus and secretory mechanisms. Contrib Nephrol 43:76-101
23. Teppo AM (1982) Immunoturbidimetry of albumin and immunoglobulin G in urine. Clin Chem 28:1359-1361
24. Viberti G, Walker JD (1991) Natural history and pathogenesis of diabetic nephropathy. J Diabetes Complications 5:72-75
25. Viberti G, Morgensen CE, Groop LC, Pauls JF (1994) Effect of captopril on progression to clinical proteinuria in patients with insulin-dependent diabetes mellitus and microalbuminuria. European Microalbuminuria Captopril Study Group (see comments). JAMA 271:275-279
26. Wright FS, Okusa MD (1990) Functional role of tubuloglomerular feedback control of glomerular filtration. Adv Nephrol Necker Hosp 19:119-133