The Mycoplasma hominis vaa gene displays a mosaic gene structure

Molecular Microbiology

Volumn 29, Issue 1, 1998, Pages 97-110

  Boesen, Thomas ^a   Emmersen, Jeppe ^a   Jensen, Lise T ^b   Ladefoged, Søren A ^b   Thorsen, Poul ^c   Birkelund, Svend ^a   Christiansen, Gunna ^a  

^a AARHUS UNIVERSITY   (Denmark)

^b AARHUS UNIVERSITY HOSPITAL   (Denmark)

^c ODENSE UNIVERSITY HOSPITAL   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

LEUCINE ZIPPER PROTEIN;

AMINO ACID TRANSPORT; AMINO TERMINAL SEQUENCE; ARTICLE; CELL ADHESION; DNA FLANKING REGION; DNA SEQUENCE; GENE CASSETTE; GENE DELETION; GENE EXPRESSION; GENE INSERTION; GENE STRUCTURE; GENETIC VARIABILITY; IMMUNOBLOTTING; MYCOPLASMA HOMINIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SEQUENCE HOMOLOGY;

ADHESINS, BACTERIAL; AMINO ACID SEQUENCE; ANTIBODIES, MONOCLONAL; BACTERIAL PROTEINS; BLOTTING, NORTHERN; EPITOPE MAPPING; EPITOPES, B-LYMPHOCYTE; GENE AMPLIFICATION; GENES, BACTERIAL; MEMBRANE PROTEINS; MICROSCOPY, IMMUNOELECTRON; MOLECULAR SEQUENCE DATA; MOSAICISM; MYCOPLASMA HOMINIS; POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS, DNA;

MYCOPLASMA HOMINIS; MYCOPLASMATALES; PROKARYOTA;

EID: 0031848188     PISSN: 0950382X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2958.1998.00906.x     Document Type: Article

References (45)

1. Andersen, H., Birkelund, S., Christiansen, G., and Freundt, E.A. (1987) Electrophoretic analysis of proteins from Mycoplasma hominis strains detected by SDS-PAGE, two-dimensional gel electrophoresis and immunoblotting. J Gen Microbiol 133: 181-191.
2. Birkelund, S., and Andersen, H. (1988) Comparative studies of mycoplasma antigens and corresponding antibodies. In Handbook of Immunoblotting of Proteins, Vol. II. Bjerrum, O.J., and Heegaard, N.H.H. (eds). Boca Raton, FL: CRC Press, pp. 25-33.
3. Birkelund, S., Lundemose, A.G., and Christiansen, G. (1988) Chemical crosslinking of Chlamydia trachomatis. Infect Immun 56: 654-659.
4. Bhugra, B., Voelker, L.L., Zou, N., Yu, H., and Dybvig, K. (1995) Mechanism of antigenic variation in Mycoplasma pulmonis: interwoven, site-specific DNA inversions. Mol Microbiol 18: 703-714.
5. Bové, J.M. (1993) Molecular features of Mollicutes. Clin Infect Dis 17: 10-31.
6. Cameron, F.H., Obbink, D.J.G., Ackermann, V.P., and Hall, P.M. (1986) Nucleotide sequence of the AAD (2′) aminoglycoside acetyltransferase determinant aadB. Evolutionary relationship of this region with those surrounding aadA in R538-1 and dhfrll in R388. Nucleic Acids Res 14: 8625-8635.
7. Chomczynski, P., and Sacchi, N. (1987) Single step method for isolation by acid guanidinium thiocyanate-phenolchloroform extraction. Anal Biochem 162: 156-159.
8. Christiansen, G. (1992) Genetic variation in natural populations. In Mycoplasmas: Molecular Biology and Pathogenesis. Maniloff, J., McElhaney, R.N., Finch, L.R., and Baseman, J.B. (eds). Washington, DC: American Society for Microbiology Press, pp. 561-573.
9. Christiansen, G., and Andersen, H. (1988) Heterogeneity among Mycoplasma hominis strains as detected by probes containing parts of ribosomal ribonucleic acid genes. Int J Syst Bacteriol 38: 108-115.
10. Christiansen, G., Ladefoged, S., Hauge, S., Birkelund, S., and Andersen, H. (1990) Use of monoclonal antibodies for detection of antigen variation in Mycoplasma hominis. In Recent Advances in Mycoplasmology. Stanek, G., Cassell, G.H., Tully, J.G., and Whitcomb, R.F. (eds). Stuttgart: Gustav Fischer, pp. 535-545.
11. Cleveland, D.W., Fischer, S.G., Kirschner, M.W., and Laemmli, U.K. (1977) Peptide mapping by limited proteolysis in sodium dodecyl sulphate and analysis by gel electrophoresis. J Biochem Chem 252: 1102-1106.
12. Collins, C.M., and Hall, R.M. (1992) Site-specific deletion and rearrangement of integron insert genes catalyzed by the DNA integrase. J Bacteriol 74: 1574-1585.
13. Devereux, J., Haerberli, P., and Smithies, O. (1984) A comprehensive set of sequence analysis programs for the VAX. Nucleic Acids Res 12: 387-395.
14. Dowson, C.G., Hutchison, A., Brannigan, J.A., George, R.C., Hansman, D., Liñares, J., et al. (1989) Horizontal transfer of penicillin-binding protein genes in penicillin-resistant clinical isolates of Streptococcus pneumoniae. Proc Natl Acad Sci USA 86: 8842-8846.
15. Dybvig, K. (1992) Gene transfer. In Mycoplasmas: Molecular Biology and Pathogenesis. Maniloff, J., McElhaney, R.N., Finch, L.R., and Baseman, J.B. (eds). Washington, DC: American Society for Microbiology Press, pp. 355-361.
16. Dybvig, K., and Voelker, L.L. (1996) Molecular biology of mycoplasmas. Annu Rev Microbiol 50: 25-57.
17. Feavers, I.M., Heath, A.B., Bygraves, J.A., and Maiden, M.C.J. (1992) Role of horizontal genetic exchange in the antigenic variation of the class 1 outer membrane protein of Neisseria meningitidis. Mol Microbiol 6: 489-495.
18. Friis, H., Plesner, A., Scheibel, J., Justesen, T., and Lind, K. (1983) Mycoplasma hominis septicaemia. Br Med J 286: 2013-2014.
19. Henrich, B., Feldmann, R.-C., and Hadding, U. (1993) Cytoadhesins of Mycoplasma hominis. Infect Immun 61: 2945-2951.
20. Henrich, B., Lubatschowski, E., and Hadding, U. (1994) A cytoadherence-mediating structure of Mycoplasma hominis (abstract). IOM Lett 3: 421-422.
21. Henrich, B., Kitzerow, A., Feldmann, R.-C., Schaal, H., and Hadding, U. (1996) Repetitive elements of the Mycoplasma hominis adhesin p50 can be differentiated by monoclonal antibodies. Infect Immun 64: 4027-4034.
22. Hollingdale, M.R., and Lemcke, R.M. (1969) The antigens of Mycoplasma hominis. J Hyg 67: 585-602.
23. Jensen, L.T., Ladefoged, S., Birkelund, S., and Christiansen, G. (1995) Selection of Mycoplasma hominis PG21 deletion mutants by cultivation in the presence of monoclonal antibody 552. Infect Immun 63: 3336-3347.
24. Klemm, P., Christiansen, G., Kreft, B., Marre, R., and Bergmans, H. (1994) Reciprocal exchange of minor components of type 1 and FC1 fimbriae results in hybrid organelles with changed receptor specificity. J Bacteriol 176: 2227-2234.
25. Lee, Y.-H., Nersasian, R.R., Lan, N.K., McDonald, A., and McCormack, W.M. (1971) Wound infection with Mycoplasma hominis. JAMA 218: 252-253.
26. Lin, J.-S., and Kass, E.H. (1974) Serological reactions of Mycoplasma hominis: differences among mycoplasmacidal, metabolic inhibition, and growth agglutination test. Infect Immun 10: 535-540.
27. Maniloff, J. (1992) Mycoplasma viruses. In Mycoplasmas: Molecular Biology and Pathogenesis. Maniloff, J., McElhaney, R.N., Finch, L.R., and Baseman, J.B. (eds). Washington, DC: American Society for Microbiology Press, pp. 41-59.
28. Martinez, E., and de la Cruz, F. (1988) Transposon Tn21 encodes a RecA-independent site-specific integration system. Mol Gen Genet 211: 320-325.
29. Maynard Smith, J., Dowson, G.G., and Spratt, B.G. (1991) Localized sex in bacteria. Nature 349: 29-31.
30. McClenaghan, M., Herring, A.J., and Aitken, I.D. (1984) Comparison of Chlamydia psittaci isolates by DNA restriction endonuclease analysis. Infect Immun 45: 384-389.
31. Nicol, C.S., and Edward, D. (1953) Role of organisms of the pleuropneumonia group in human genital infection. Br J Ven Dis 29: 141-150.
32. Nyvold, C., Birkelund, S., and Christiansen, G. (1997) The Mycoplasma hominis P120 membrane protein contains a 216 amino acid hypervariable domain that is recognized by the human humoral immune response. Microbiology 143: 675-688.
33. Olson, L.D., Shane, S.W., Karpas, A.A., Cunningham, T.M., Probst, P.S., and Barile, M.F. (1991a) Monoclonal antibodies to surface antigens of a pathogenic Mycoplasma hominis strain. Infect Immun 59: 1683-1689.
34. Olson, L.D., Renshaw, C.A., Shane, S.W., and Barile, M.F. (1991b) Successive synovial Mycoplasma hominis isolates exhibit apparent antigenic variation. Infect Immun 59: 3327-3329.
35. Oullette, M., Bissonette, L., and Roy, P.H. (1987) Precise insertion of antibiotic resistance determinants into Tn21-like transposons: nucleotide sequencing of the OXA-1 β-lactamase gene. Proc Natl Acad Sci USA 84: 7378-7382.
36. Sambrook, J., Fritsch, E.F., and Maniatis, T. (1989) Molecular Cloning: a Laboratory Manual, 2nd edn. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press.
37. Scopes, R.K. (1994) Protein Purification: Principles and Practice, 3rd edn. New York: Springer-Verlag.
38. Spratt, B.G. (1988) Hybrid penicillin-binding proteins in penicillin-resistant strains of Neisseria gonorrhoeae. Nature 332: 173-176.
39. Spratt, B.G., Zhang, Q.-Y., Jones, D.M., Hutchison, A., Brannigen, J.A., and Dowson, G.G. (1989) Recruitment of a penicillin-binding protein gene from Neisseria flavesens during the emergence of penicillin resistance in Neisseria meningitidis. Proc Natl Acad Sci USA 86: 8988-8992.
40. Taylor-Robbinson, D., Somerson, N.L., Turner, H.C., and Chanok, R.M. (1963) Serological relationships among human mycoplasmas as shown by complement-fixation and gel diffusion. J Bacteriol 85: 1261-1273.
41. Thomsen, A.C. (1978) Mycoplasmas in human pyelonephritis: demonstration of antibodies in serum and urine. J Clin Microbiol 8: 197-202.
42. Tully, J.G. (1983) Cloning and filtration techniques for mycoplasmas. In Methods in Mycoplasmology, Vol. 1. Razin, S., and Tully, J.G. (eds). New York: Academic Press, pp. 173-177.
43. Wise, K.S. (1993) Adaptive surface variations in mycoplasmas. Trends Microbiol 1: 59-63.
44. Zhang, Q., and Wise, K.S. (1996) Molecular basis of size and antigenic variation of a Mycoplasma hominis adhesin encoded by divergent vaa genes. Infect Immun 64: 2737-2744.
45. Zhang, Q., and Wise, K.S. (1997) Localized reversible frameshift mutation in an adhesin gene confers a phase-variable adherence phenotype in mycoplasma. Mol Microbil 25: 859-869.