Covalent binding of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline to albumin and hemoglobin at environmentally relevant doses: Comparison of human subjects and f344 rats

Drug Metabolism and Disposition

Volumn 26, Issue 8, 1998, Pages 825-828

  Dingley, Karen H ^a   Freeman, Stewart P H T ^b   Nelson, David O ^b   Garner, R Colin ^b   Turteltaub, Kenneth W ^b  

^a LAWRENCE LIVERMORE NATIONAL LABORATORY   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINO 3,8 DIMETHYLIMIDAZO[4,5 F]QUINOXALINE; ALBUMIN; HEMOGLOBIN;

AGED; ANIMAL EXPERIMENT; ARTICLE; COLON RESECTION; CONTROLLED STUDY; COVALENT BOND; DRUG DETERMINATION; DRUG PROTEIN BINDING; HUMAN; MASS SPECTROMETRY; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; RAT;

ADULT; AGED; ANIMALS; CARBON RADIOISOTOPES; CARCINOGENS; DOSE-RESPONSE RELATIONSHIP, DRUG; HEMOGLOBINS; HUMANS; MALE; MASS SPECTROMETRY; PROTEIN BINDING; QUINOXALINES; RATS; RATS, INBRED F344; SENSITIVITY AND SPECIFICITY; SERUM ALBUMIN;

ANIMALIA;

EID: 0031844149     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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