TNF-α Bidirectionally Modulates the Viability of Primitive Murine Hematopoietic Progenitor Cells in Vitro

Journal of Immunology

Volumn 157, Issue 3, 1996, Pages 1193-1199

  Jacobsen, Frede W ^a   Veiby, Ole P ^b,c   Stokke, Trond ^a   Jacobsen, Sten E W ^a,c  

^a OSLO UNIVERSITY HOSPITAL   (Norway)

^b ALTANA PHARMA AG   (Germany)

^c Cancer Prevention Institute Dayton   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GRANULOCYTE COLONY STIMULATING FACTOR; INTERLEUKIN 11; INTERLEUKIN 6; STEM CELL FACTOR; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL; APOPTOSIS; ARTICLE; CELL SURVIVAL; CYTOLOGY; DRUG EFFECT; FLOW CYTOMETRY; HEMATOPOIETIC STEM CELL; IN VITRO STUDY; METABOLISM; MOUSE; PHYSIOLOGY;

ANIMALS; APOPTOSIS; CELL SURVIVAL; FLOW CYTOMETRY; GRANULOCYTE COLONY-STIMULATING FACTOR; HEMATOPOIETIC STEM CELLS; INTERLEUKIN-11; INTERLEUKIN-6; MICE; STEM CELL FACTOR; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0030210954     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (48)

1. Metcalf, D. 1989. The molecular conlrol of cell division, differentiation, commitment, and maturation in hematopoietic cells. Nature 339:27.
2. Whetton, A. D., and T. M. Dexter. 1989. Myeloid haemopoietic growth factors. Biochim. Biophys. Acta 989:111.
3. Moore, M. A. S. 1991. Clinical implications of positive and negative hematopoietic stem cell regulators. Blood 78:1.
4. Metcalf, D. 1993. Hematopoietic regulators: redundancy or subtlety? Blood 82: 3515.
5. Leary, A. G., Y. Hirai, T. Kishimoto, S. C. Clark, and M. Ogawa. 1989. Proc. Natl. Acad. Sci. USA 86:4535.
6. Williams, D. E., and H. E. Broxmeyer. 1988. Interleukin-1α enhances the in vitro survival of purified murine granulocyte-macrophage progenitor cells in the absence of colony-stimulating factors. Blood 72:1608.
7. Hangoc, G., D. E. Williams, J. F. H. Falkenburg, and H. E. Broxmeyer. 1989. Influence of IL-1α and IL-1β on the survival of human bone marrow cells responding to hematopoietic colony-stimulating factors. J. Immunol. 142:4329.
8. 0 and entry into the cell cycle of primitive human hemopoietic progenitors. Proc. Natl. Acad. Sci. USA 89:4013.
9. Katayama, N., S. C. Clark, and M. Ogawa. 1993. Growth factor requirement for survival in cell-cycle dormancy of primitive murine lymphohematopoietic progenitors. Blood 81:610.
10. Li, C. L., and G. R. Johnson. 1994. Stem cell factor enhances the survival but not the self-renewal of murine hematopoietic long-term repopulating cells. Blood 84:408.
11. Brandt, J. E., K. Bhalla, and R. Hoffman. 1994. Effects of interleukin-3 and c-kit ligand on the survival of various classes of human hematopoietic progenitor cells. Blood 83:1507.
12. Keller, J. R., M. Ortiz, and F. W. Ruscetti. 1995. Steel factor (e-kit ligand) promotes the survival of hematopoietic stem/progenitor cells in the absence of cell division. Blood 86:1757.
13. Jacobsen, S. E. W., F. W. Jacobsen, C. Fahlman, and L. S. Rusten. 1994. TNF-α, the great imitator: role of p55 and p75 TNF receptors in hematopoiesis. Stem Cells 12(Suppl. 1):111.
14. Degliantoni, G., M. Murphy, M. Kobayashi, M. K. Francis, B. Perussia, and G. Trinchieri. 1985. Natural killer (NK) cell-derived hematopoietic colony-inhibiting activity and NK cytotoxic factor: relationship with tumor necrosis factor and synergy with immune interferon. J. Exp. Med. 162:1512.
15. Broxmeyer, H. E., D. E. Williams, L. Lu, S. Cooper, S. L. Anderson, G. S. Beyer, R. Hoffman, and B. Y. Rubin. 1986. The suppressive influences of human tumor necrosis factors on bone marrow hematopoietic progenitor cells from normal donors and patients with leukemia: synergism of tumor necrosis factor and interferon-γ. J. Immunol. 136:4487.
16. Murphy, M., B. Perussia, and G. Trinchieri. 1988. Effects of recombinant tumor necrosis factor on the colony growth of human leukemia progenitor cells and normal hematopoietic progenitor cells. Blood 69:467.
17. Caux, C., C. Favre, S. Saeland, V. Duvert, I. Durand, P. Mannoni, and J. Banchereau. 1991. Potentiation of early hematopoiesis by tumor necrosis factor-α is followed by inhibition of granulopoietic differentiation and proliferation. Blood 78:635.
18. Backx, B., L. Broeders, F. J. Bot, and B. Löwenberg. 1991. Positive and negative effects of tumor necrosis factor on colony growth from highly purified normal marrow progenitors. Leukemia 5:66.
19. Jacobsen, S. E. W., F. W. Ruscetti, C. M. Dubois, and J. R. Keller. 1992. Tumor necrosis factor α directly and indirectly regulates hematopoietic progenitor cell proliferation: role of colony-stimulating factor receptor modulation. J. Exp. Med. 175:1759.
20. Jacobsen, F. W., M. Rothe, L. Rusten, D. V. Goeddel, E. B. Smeland, O. P. Veiby, L. Størdal, and S. E. W. Jacobsen. 1994. Role of the 75-kDa tumor necrosis factor receptor: inhibition of early hematopoiesis. Proc. Natl. Acad. Sci. USA 91:10695.
21. Rusten, L. S., E. B. Smeland, F. W. Jacobsen, E. Lien, W. Lesslauer, H. Loetscher, C. M. Dubois, and S. E. W. Jacobsen. 1994. Tumor necrosis factor-α inhibits stem cell factor-induced proliferation of human bone marrow progenitor cells in vitro. J. Clin. Invest. 94:165.
22. Rusten, L. S., F. W. Jacobsen, W. Lesslauer, H. Loetscher, E. B. Smeland, and S. E. W. Jacobsen. 1994. Bifunctional effects of TNF-α on the growth of mature and primitive human hematopoietic progenitor cells: involvement of p55 and p75 TNF receptors. Blood 83:3152.
23. Jacobsen, F. W., C. M. Dubois, L. S. Rusten, O. P. Veiby, and S. E. W. Jacobsen. 1995. Inhibition of SCF-induced proliferation of primitive marine hematopoietic progenitor cells signaled through the 75-kDa tumor necrosis factor receptor: role of modulation of c-kit and p53 expression. J. Immunol. 154:3732.
24. + hematopoietic progenitor cells. Blood 75:2292.
25. Laster, S. M., J. G. Wood, and L. R. Gooding. 1988. Tumor necrosis factor can induce both apoptic and necrotic forms of cell lysis. J. Immunol. 141:2629.
26. Dealtry, G. B., M. S. Naylor, W. Fiers, and F. R. Balkwill. 1987. DNA fragmentation and cytotoxicity caused by tumor necrosis factor is enhanced by interferon-γ. Eur. J. Immunol. 17:689.
27. Schmid, D. S., J. P. Tite, and N. H. Ruddle. 1986. Manifestation of target cell destruction mediated by cytotoxic T-cell lines, lymphotoxin-secreting helper T-cell clones, and cell-free lymphotoxin-containing supernatant. Proc. Natl. Acad. Sci. USA 83:1881.
28. Elias, L., P. B. Moore, and S. M. Rose. 1988. Tumor necrosis factor induced DNA fragmentation of HL-60 cells. Biochem. Biophys. Res. Commun. 157:963.
29. Rubin, B. Y., L. J. Smith, G. R. Hellermann, R. M. Lunn, N. K. Richardson, and S. L. Anderson. 1988. Correlation between the anticellular and DNA-fragmenting activities of tumor necrosis factor. Cancer Res. 48:6006.
30. Hernandez-Caselles, T., and O. Stutman. 1993. Immune functions of TNF. I. TNF induces apoptosis of mouse thymocytes and can also stimulate or inhibit IL-6-induced proliferation depending on the concentration of mitogenic costimulation. J. Immunol. 151:3999.
31. Spangrude, G. J., S. Heimfeld, and I. L. Weissman. 1988. Purification and characterization of mouse hematopoietic stem cells. Science 241:58.
32. Spangrude, G. J., and R. Scollay. 1990. A simplified method for enrichment of mouse hematopoietic stem cells. Exp. Hematol. 18:920.
33. Spangrude, G. J. 1992. Characteristics of the hematopoietic stem cell compartment in adult mice. Int. J. Cell Cloning 10:277.
34. Gorczyca, W., J. Gong, and Z. Darzynkiewicz. 1993. Detection of DNA strand breaks in individual apoptotic cells by the in situ terminal deoxynucleotidyl transferase and nick translation assays. Cancer Res. 53:1945.
35. Johnson, G. D., and G. M. C. Nogueria Araujo. 1981. A simple method of reducing the fading of immunofluorescence during microscopy. J. Immunol. Methods 43:349.
36. Williams, N., I. Bertoncello, H. Kavnoudias, K. Zsebo, and I. McNiece. 1992. Recombinant rat stem cell factor stimulates the amplification of fractionated mouse stem cell populations. Blood 79:58.
37. + hemopoietic stem cells. J. Exp. Med. 175:1443.
38. Tsuji, K., S. D. Lyman, T. Sudo, S. C. Clark, and M. Ogawa, 1992. Enhancement of murine hematopoiesis by synergistic interactions between steel factor (ligand for c-kit), interleukin-11, and other early acting factors in culture. Blood 79:2855.
39. Williams, G. T. 1995. Apoptosis in the immune system: concepts and questions. In Apoptosis and the Immune Response. Gregory CD, ed. Wiley-Liss, New York, p. 1.
40. Lotem, J., and L. Sachs. 1992. Hematopoietic cytokines inhibit apoptosis induced by transforming growth factor β1 and cancer chemotherapy compounds in myeloid leukemic cells. Blood 80:1750.
41. Heimfeld, S., S. Hudak, I. Weissman, and D. Rennick. 1991. The in vitro response of phenotypically defined mouse stem cells and myeloerythroid progenitors to single or multiple growth factors. Proc. Natl. Acad. Sci. USA 88:9902.
42. Sachs, L., and J. Lotem. 1993. Control of programmed cell death in normal and leukemic cells: new implications for therapy. Blood 82:15.
43. Williams, G. T., C. A. Smith, E. Spooncer, T. M. Dexter, and D. R. Taylor. 1990. Haematopoietic colony-stimulating factors promote cell survival by suppressing apoptosis. Nature 343:76.
44. Koury, M. J., and M. C. Bondurant. 1990. Erythropoietin retards DNA breakdown and prevents programmed death in erythroid progenitor cells. Science 248: 378.
45. Selleri, C., T. Sato, S. Anderson, N. S. Young, and J. P. Maciejewski. 1995. Interferon-γ and tumor necrosis factor-α suppress both early and late stages of hematopoiesis and induce programmed cell death. J. Cell. Physiol. 165:538.
46. Jacobsen, F. W., T. Stokke, and S. E. W. Jacobsen. 1995. Transforming growth factor-β potently inhibits the viability-promoting activity of stem cell factor and other cytokines and induces apoptosis of primitive murine hematopoietic progenitor cells. Blood 86:2957.
47. Li, C. L., and G. R. Johnson. 1995. Murine hematopoietic stem and progenitor cells. I. Enrichment and biologic characterization. Blood 85:1472.
48. Neta, R., J. J. Oppenheim, and S. D. Douches. 1988. Interdependence of the radioprotective effects of human recombinant interleukin-1α, tumor necrosis factor-α, granulocyte colony-stimulating factor, and murine recombinant granulocyte-macrophage colony-stimulating factor. J. Immunol. 140:108.