Effect of diet on the rate of depletion of n-3 fatty acids in the retina of the guinea pig

Journal of Lipid Research

Volumn 39, Issue 6, 1998, Pages 1274-1279

  Weisinger, Harrison S ^a   Vingrys, Algis J ^a   Abedin, Lavinia ^b   Sinclair, Andrew J ^a,b  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b RMIT UNIVERSITY   (Australia)

Author keywords

Alpha linolenic acid; Docosahexaenoic acid; Maternal diet; n 3 polyunsaturated fatty acids; Retinal lipids

Indexed keywords

DOCOSAHEXAENOIC ACID; LINOLEIC ACID; OMEGA 3 FATTY ACID;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ESSENTIAL FATTY ACID DEFICIENCY; FAT INTAKE; GUINEA PIG; INFANT NUTRITION; LIPID COMPOSITION; MATERNAL NUTRITION; NONHUMAN; NUTRITIONAL DEFICIENCY; PRIORITY JOURNAL; RETINA; WEANING;

ALPHA-LINOLENIC ACID; ANIMALS; DIETARY FATS; FATTY ACIDS, MONOUNSATURATED; FATTY ACIDS, OMEGA-3; FATTY ACIDS, OMEGA-6; FATTY ACIDS, UNSATURATED; GUINEA PIGS; HUMANS; PHOSPHOLIPIDS; RETINA; SAFFLOWER OIL; TIME FACTORS; WEANING;

EID: 0031839308     PISSN: 00222275     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. Crawford, M. A., N. M. Casperd, and A. J. Sinclair. 1976. The long chain metabolites of linoleic and linolenic acids in liver and brain in herbivores and carnivores. Comp. Biochem. Physiol. 54B: 395-401.
2. Leat, W. M. F., R. Curtis, N. J. Millichamp, and R. W. Cox. 1986. Retinal function in rats and guinea pigs reared on diets low in essential fatty acids and supplemented with linoleic or linolenic acids. Ann. Nutr. Metab. 30: 166-174.
3. Weisinger, H. S., A. J. Vingrys, and A. J. Sinclair. 1996. The effect of dietary n-3 deficiency on the electroretinogram in the guinea pig. Ann. Nutr. Metab. 40: 91-98.
4. Weisinger, H. S., A. J. Vingrys, and A. J. Sinclair. 1996. The effect of docosahexaenoic acid on the electroretinogram of the guinea pig. Lipids. 31: 65-70.
5. Weisinger, H. S., A. J. Vingrys, and A. J. Sinclair. 1995. Dietary manipulation of long chain polyunsaturated fatty acids in the retina and brain of guinea pigs. Lipids. 30: 471-473.
6. Neuringer, M., W. E. Connor, D. S. Lin, L. Barstad, and S. J. Luck. 1986. Biochemical and functional effects of prenatal and postnatal omega-3 fatty acid deficiency on retina and brain in rhesus monkeys. Proc. Natl. Acad. Sci. USA. 83: 4021-4025.
7. Bourre, J. M., M. Francois, A. Youyou, O. Dumont, M. Piciotti, G. Pascal, and G. Durand. 1989. The effects of dietary α-linolenic acid on the composition of nerve membranes, enzymatic activity, amplitude of electrophysiological parameters, resistance to poisons and performance of learning tasks in rats. J. Nutr. 119: 1880-1892.
8. Neuringer, M., W. E. Connor, D. S. Lin, and G. J. Anderson. 1993. Effects of n-3 fatty acid deficiency on retinal physiology and visual function. In Essential Fatty Acids and Eicosanoids. A. J. Sinclair and R. A. Gibson, editors. American Oil Chemists' Society, Champaign, IL. 161-164.
9. Ward, G., J. Woods, M. Reyzer, and N. Salem. 1996. Artificial rearing of infant rats on milk formula deficient in n-3 essential fatly acids: a rapid method for the production of experimental n-3 deficiency. Lipids. 31: 71-78.
10. Sinclair, A. J., K. O'Dea, G. Dunstan, P. D. Ireland, and M. Niall. 1987. Effects of plasma lipids and fatty acid composition of very low fat diets enriched with fish of kangaroo meat. Lipids. 22: 523-529.
11. Press, W. H., S. A. Teukolsky, W. T. Vetterling, and B. P. Flannery. 1992. Numerical Recipes In C. 2nd edition. Cambridge University Press, Cambridge.
12. Bazan, N. G., W. C. Gordon, and E. B. Rodriguez De Turco. 1993. The uptake, metabolism and conservation of docosahexaenoic acid (22:6n-3) in brain and retina: alterations in liver and retinal 22:6 metabolism during inherited progressive retinal degeneration. In Essential Fatty Acids and Eicosanoids. A. J. Sinclair and R. A. Gibson, editors. American Oil Chemists' Society. Champaign, IL. 107-115.
13. Stinson, A. M., R. D., Wiegand, and R. E. Anderson. 1991. Recycling of docosahexaenoic acid in rat retinas during n-3 deficiency. J. Lipid Res. 32: 2009-2017.
14. Woods, J., G. Ward, and N. Salem. 1996. Is docosahexaenoic acid necessary in infant formula? Evaluation of high linolenate diets in the neonatal rat. Pediatr. Res. 40: 1-7.