Histologic confirmation of microvascular hyperpermeability to macromolecular MR contrast medium in reperfused myocardial infarction

Journal of Magnetic Resonance Imaging

Volumn 8, Issue 3, 1998, Pages 561-567

  Saeed, Maythem ^a   Van Dijke, Cornelis F ^a   Mann, Jeffrey S ^a   Wendland, Michael F ^a   Rosenau, Werner ^a   Higgins, Charles B ^a   Brasch, Robert C ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Capillary permeability; Contrast media; MRI; Myocardial ischemia; Reperfused myocardial infarction

Indexed keywords

AVIDIN; BIOTIN; GADOLINIUM PENTETATE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTRAST ENHANCEMENT; CONTROLLED STUDY; DATA ANALYSIS; FEMALE; HEART INFARCTION; HEART MUSCLE PERFUSION; HISTOPATHOLOGY; HUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; RAT;

ALBUMINS; ANIMALS; CAPILLARY PERMEABILITY; CONTRAST MEDIA; CORONARY VESSELS; EXTRACELLULAR SPACE; FEMALE; GADOLINIUM DTPA; IMMUNOENZYME TECHNIQUES; MACROMOLECULAR SUBSTANCES; MAGNETIC RESONANCE IMAGING; MICROCIRCULATION; MYOCARDIAL INFARCTION; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0031835763     PISSN: 10531807     EISSN: None     Source Type: Journal    
DOI: 10.1002/jmri.1880080308     Document Type: Article

References (33)

1. Ito H, Toomoko T, Sakai N, et al. Lack of myocardial perfusion immediately after successful thrombolysis. Circulation 1992; 85:1699-1705.
2. de Roos A, van Rossum AC, van der Wall AC, et al. Reperfused and nonreperfused myocardial infarction: diagnostic potential of Gd-DTPA-enhanced MR imaging. Radiology 1989; 172:717-720.
3. Austin RE, Aldea GS, Coggins DL, Flynn AE, Hoffman JIE. Profound spatial heterogeneity of coronary reserve. Discordance between patterns of resting and maximal myocardial blood flow. Circ Res 1990; 67:319-331.
4. Harden WR, Barlow CH, Simon MB, Harken AH. Heterogeneity of coronary microcirculation during low-flow ischemia: a model of the heart shock. Adv Shock Res 1980; 3:239-250.
5. Ince C, Ashruf JF, Avontuur JAM, Wieringa PA, Spaan JAE, Bruining HA. Heterogeneity of the hypoxic state in the rat heart is determined at capillary level. Am J Physiol 1993; 264: H294-H301.
6. Ward BJ, Donnelly JL. Hypoxia induced disruption of the cardiac endothelial glycocalyx: implication for capillary permeability. Cardiovasc Res 1993; 27:384-389.
7. Schmiedl U, Ogan MD, Paajanen H, et al. Albumin labeled with Gd-DTPA as an intravascular, blood-pool-enhancing agent for MR imaging: biodistribution and imaging studies. Radiology 1987; 162:205-210.
8. Brasch RC. New development in MRI contrast enhancement. Radiology 1992; 183:1-11.
9. Demsar F, Roberts TP, Schwickert HC, et al. A MRI spatial mapping technique for microvascular permeability and tissue volume based on macromolecular contrast agent distribution. Magn Reson Med 1997; 37:236-242.
10. Shames D, Kuwatsuru R, Vexler V, Muehler A, Brasch RC. Measurement of capillary permeability to macromolecules by dynamic magnetic resonance imaging: a quantitative non-invasive technique. Magn Reson Med 1993; 29:616-622.
11. Cohen F, Kuwatsuru R, Shames D, et al. Contrast-enhanced magnetic resonance imaging estimation of altered capillary permeability in experimental mammary carcinomas after X-radiation. Invest Radiol 1994; 29:970-977.
12. Saeed M, Wendland MF, Masui T, et al. Myocardial infarction: assessment with an intravascular MR medium. Radiology 1991; 180:153-160.
13. Schmiedl U, Moseley ME, Sievers R, et al. Magnetic resonance imaging of myocardial infarction in rats using albumin-(Gd-DTPA), a macromolecular blood-volume contrast agent in a rat model. Invest Radiol 1987; 22:713-721.
14. Schmiedl U, Sievers R, Brasch RC, et al. Acute myocardial ischemia and reperfusion: MR imaging with albumin-(Gd-DTPA). Radiology 1989; 170:351-356.
15. Wolfe CL, Moseley ME, Wikstrom MG, et al. Assessment of myocardial salvage after ischemia and reperfusion using magnetic resonance imaging and spectroscopy. Circulation 1989; 80:969-982.
16. Wilke N, Kroll K, Merkte H, et al. Regional myocardial blood volume and flow; first-pass MR imaging with polylysine-Gd-DTPA. J Magn Reson Imaging 1995; 5:227-238.
17. Schwickert HC, Saeed M, Roberts TPL, Muhler A. Shames DM, Brasch RC. Reperfused irreversible myocardial infarction: MRI enhancement and microvascular permeability quantification with Gd-DTPA-24-cascade-polymer. In: Book of abstracts: Society of Magnetic Resonance. Berkeley, CA: Society of Magnetic Resonance, 1995; 1407.
18. Mann JF, van Dijke CF, Rosenau W, Brasch RC. HSA-(biotin)10-(Gd-DTPA)25. Histological and MRI visualization of abnormal capillary permeability to a macromolecular contrast agent in a breast tumor model. In: Book of abstracts: Society of Magnetic Resonance. Berkeley, CA: Society of Magnetic Resonance, 1995; 1136.
19. Ogan MD, Schmiedl U, Moseley ME, Grodd W, Paajanen H, Brasch RC. Albumin labeled with Gd-DTPA: an intravascular contrast-enhancing agent for magnetic resonance blood pool imaging: preparation and characterization. Invest Radial 1987; 22:665-671.
20. Aldwin L, Nitecki DE. Water soluble, monitoable peptide and protein crosslinklng agent. Anal Biochem 1987; 164:494-501.
21. Siever RE, Schmiedl U, Wolfe CL, et al. A model of acute regional myocardial ischemia and reperfusion in the rat. Magn Reson Med 1989; 10:172-181.
22. Hsu SM, Soban E. Color modification of diaminobezidine (DAB) precipitation by metallic ions and its application to double immunochemistry. J Histochem Cytochem 1982; 30:1079-1082.
23. Sternberger LA, Sternberger NH. The unlabeled antibody method: comparison of perocisase-antiperoxidase with avidin-biotin complex by a new method of quantification. J Histochem Cytochem 1986; 34:599-605.
24. Wendland MF, Saeed M, Yu KK, et al. Inversion recovery EPI of bolus transit in rat myocardium using intravascular and extravascular gadolinium-based MR contrast media: dose effects on peak signal enhancement. Magn Reson Med 1994; 132:319-329.
25. Tilton RG, Larson KB, Williamson JR. Prolonged vascular washout of 125I-BSA following ischemic injury to the heart. Microvasc Res 1981; 21:260.
26. Lim T-H, Lee JH, Gong G, Park S-J, Lee I. Significance of magnetic resonance signal enhancement in evaluation of myocardial infarction in cats. Invest Radiol 1995; 30:306-314.
27. Baldwin AL, Wu NZ, Stein DL. Endothelial surface charge of intestinal mucosal capillaries and it modulation by dextran. Microvasc Res 1991; 42:160-178.
28. Kloner RA, Ganote CE, Jennings RB. The "no-reflow" phenomenon of the temporary coronary occlusion in the dogs. J Clin Invest 1974; 54:1496-1508.
29. Arts T, Reneman RS. Interaction between intramyocardial pressure (IMP) and myocardial circulation. J Biomech Eng 1985; 107:51-56.
30. Schwitter J, Saeed M, Wendland MF, et al. Influence of the severity of myocardial injury on the distribution of macromolecules: extra versus intra-vascular gadolinium-based MR contrast media. J Am Coll Cardiol 1997; 30:1084-1094.
31. Ullal SR, Kluge TH, Kerty WJ, Gerbode F. Changes in cardiac lymph of dogs during and after anoxia. Ann Surg 1972; 175: 472-478.
32. Sutherland TM, Young DAB. Increased permeability of the capillaries of the rat heart to plasma albumin with asphyxiation with reperfusion. J Physiol 1966; 183:112-122.
33. Wendland MF, Saeed M, Geschwind J-F, Brasch RC, Higgins CB. Distribution of intracellular, extracellular, and intravascular contrast media for magnetic resonance imaging in hearts subjected to reperfused myocardial infarction. Acad Radiol 1996; 3:S402-S404.