Studies on nonpeptide angiotensin II receptor antagonists. III. Synthesis and biological evaluation of 5-alkylidene-3,5-dihydro-4H-imidazol- 4-one derivatives

Chemical and Pharmaceutical Bulletin

Volumn 46, Issue 5, 1998, Pages 777-781

  Okazaki, Toshio ^a   Kikuchi, Kazumi ^a   Watanabe, Toshihiro ^a   Suga, Akira ^a   Shibasaki, Masayuki ^a   Fujimori, Akira ^a   Inagaki, Osamu ^a   Yanagisawa, Isao ^a  

^a ASTELLAS PHARMA INC   (Japan)

Author keywords

Angiotensin II; Antihypertensive; Dihydroimidazole; Nonpeptide angiotensin II antagonist

Indexed keywords

3,5 DIHYDRO 5 (1 METHYLETHYLIDENE) 2 PROPYL 3 [[2 (1H TETRAZOL 5 YL)BIPHENYL 4 YL]METHYL] 4H IMIDAZOL 4 ONE; ANGIOTENSIN 2 RECEPTOR ANTAGONIST; UNCLASSIFIED DRUG;

ANIMAL MODEL; ANIMAL TISSUE; ANTIHYPERTENSIVE ACTIVITY; ARTICLE; DRUG ACTIVITY; DRUG SYNTHESIS; HYPERTENSION; NONHUMAN; ORAL DRUG ADMINISTRATION; PRESSOR RESPONSE; RABBIT; RAT; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

EID: 0031834604     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.46.777     Document Type: Article

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