Runt determines cell fates in the Drosophila embryonic CNS

Development

Volumn 125, Issue 9, 1998, Pages 1659-1667

  Dormand, Emma Louise ^a   Brand, Andrea H ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Cell fate; CNS; Drosophila; Neuroblast; Neurogenesis; runt

Indexed keywords

GREEN FLUORESCENT PROTEIN; TRECOVIRSEN;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DEVELOPMENTAL GENETICS; DROSOPHILA; EMBRYO; EMBRYO DEVELOPMENT; EMBRYO SEGMENTATION; GENE; GENE EXPRESSION; NERVE FIBER; NERVOUS SYSTEM DEVELOPMENT; NEUROBLAST; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; AXONS; BACTERIAL PROTEINS; CENTRAL NERVOUS SYSTEM; DNA-BINDING PROTEINS; DROSOPHILA; DROSOPHILA PROTEINS; EMBRYO, NONMAMMALIAN; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HOMEODOMAIN PROTEINS; NEUROGLIA; NEURONS; NUCLEAR PROTEINS; RECOMBINANT FUSION PROTEINS; TRANSCRIPTION FACTORS;

ANIMALIA; HEXAPODA; INSECTA;

EID: 0031831564     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (48)

1. Bastiani, M. J., du Lac, S. and Goodman, C. S. (1986). Guidance of neuronal growth cones in the grasshopper embryo. J. Neurosci. 6, 3518-3531.
2. Bhat, K. M. (1996). The patched signalling pathway mediates repression of gooseberry allowing neuroblast specification by wingless during Drosophila neurogenesis. Development 122, 2921-2932.
3. Bhat, K. M. and Schedl, P. (1997). Requirement for engrailed and inverted genes reveals novel regulatory interactions between engrailed/invected, patched, gooseberry and wingless during Drosophila neurogenesis. Development 124, 1675-1688.
4. Bossing, T., Udolph, G., Doe, C. Q. and Technau, G. M. (1996). The embryonic central nervous system lineages of Drosophila melanogaster I. Neuroblast lineages derived from the ventral half of the neuroectoderm. Dev. Biol. 179, 41-64.
5. Brand, A. H. (1995). GFP in Drosophila. Trends in Genetics 11, 324-325.
6. Brand, A. H. and Dormand, E. L. (1995). The GAL4 system as a tool for unravelling the mysteries of the nervous system. Curr. Opin. Neuro. 5, 572-578.
7. Brand, A. H., Manoukian, A. S. and Perrimon, N. (1994). Ectopic expression in Drosophila. In Drosophila: Practical Uses in Cell and Molecular Biology (ed. L. S. B. Goldstein and E. A. Fyrberg). Vol. 44, pp. 635-654. San Diego: Academic Press.
8. Brand, A. H. and Perrimon, N. (1993). Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118, 401-415.
9. Broadus, J., Skeath, J. B., Spana, E. P., Bossing, T., Technau, G. and Doe, C. Q. (1995). New neuroblast markers and the origin of the aCC/pCC neurons in the Drosophila central nervous system. Mech. Dev. 53, 393-402.
10. Buenzow, D. E. and Holmgren, R. (1995). Expression of the Drosophila gooseberry locus defines a subset of neuroblast lineages in the central nervous system. Dev. Biol. 170, 338-349.
11. Butner, K. A. and Kirschner, M. W. (1991). Tau protein binds to microtubules through a flexible array of distributed weak sites. J. Cell Biol. 115, 717-730.
12. Callahan, C. A. and Thomas, J. B. (1994). Tau beta-galactosidase, an axon targeted fusion protein. Proc. Nat. Acad. Sci. USA 91, 5972-5976.
13. Campos-Ortega, J. A. and Hartenstein, V. (1985). Embryonic Development of Drosophila melanogaster. Berlin Heidelberg: Springer-Verlag.
14. Chu-LaGraff, Q. and Doe, C. Q. (1993). Neuroblast specification and formation regulated by wingless in the Drosophila CNS. Science 261, 1594-1597.
15. Dittrich, R., Bossing, T., Gould, A. P., Technau, G. M. and Urban, J. (1997). The differentiation of the serotonergic neurons in the Drosophila ventral nerve cord depends on the combined function of the zinc finger proteins Eagle and Huckebein. Development 124, 2515-2525.
16. Doe, C. Q. (1992). Molecular markers for identified neuroblasts and ganglion mother cells in the Drosophila central nervous system. Development 116, 855-863.
17. Doe, C. Q., Smouse, D. and Goodman, C. S. (1988). Control of neuronal fate by the Drosophila segmentation gene even-skipped. Nature 333, 376-388.
18. Doe, C. Q. and Technau, G. M. (1993). Identification and cell lineage of individual neural precursors in the Drosophila CNS. Trends in NeuroSci. 16, 510-514.
19. Duffy, J. B., Kania, M. A. and Gergen, J. P. (1991). Expression and function of the Drosophila gene runt in early stages of neural development. Development 113, 1223-1230.
20. Duman-Scheel, M., Xuelin, U, Orlov, I., Noll, M. and Patel, N. H. (1997). Genetic separation of the neural and cuticular patterning functions of gooseberry. Development 124, 2855-2865.
21. Frasch, M., Hoey, T., Rushlow, C., Doyle, H. and Levine, M. (1987). Caracterization and localisation of the even-skipped protein of Drosophila. EMBO J. 6, 749-759.
22. Golling, G., Li, L. H., Pepling, M., Stebbins, M. and Gergen, J. P. (1996). Drosophila homologues of the protooncogene product PEBP2/CBF-beta regulate the DNA-binding properties of runt. Mol. Cell. Biol. 16, 932-942.
23. Goodman, C. S. and Doe, C. Q. (1993). Embryonic development of the Drosophila central nervous system. In The Development of Drosophila melanogaster (ed. M. Bate and A. Martinez Arias), Vol. II, pp. 1131-1206. New York: CSHL Press.
24. Heim, R., Cubitt, A. B. and Tsien, R. Y. (1995). Improved green fluorescence. Nature 373, 663-664.
25. Heim, R. and Tsien, R. Y. (1996). Engineering green fluorescent protein for improved brightness, longer wavelengths and fluorescence resonance energy transfer. Curr. Biol. 6, 178-182.
26. Hidalgo, A. and Brand, A. H. (1997). Targeted neuronal ablation: the role of pioneer neurons in guidance and fasciculation in the CNS of Drosophila. Development 124, 3253-3262.
27. Hidalgo, A., Urban, J. and Brand, A. H. (1995). Targeted ablation of glia disrupts axon tract formation in the Drosophila CNS. Development 121, 3703-3712.
28. Higashijima, S., Shishido, E., Matsuzadi, M. and Saigo, K. (1996). eagle, a member of the steroid receptor gene superfamily, is expressed in a subset of neuroblasts and regulates the fate of their putative progeny in the Drosophila CNS. Development 122, 527-536.
29. Ito, K., Urban, J. and Technau, G. M. (1995). Distribution, classification, and development of Drosophila glial cells In the late embryonic and early larval ventral nerve cord. Roux's Arch. Dev. Biol. 204, 284-307.
30. Kagoshima, H., Shigesada, K., Satake, M., Ito, Y., Miyoshi, H., Ohki, M., Pepling, M. and Gergen, J. P. (1993). The Runt domain identifies a new family of heteromeric transcriptional regulators. Trends in Genetics 9, 338-341.
31. Kania, M. A., Bonner, A. S., Duffy, J. B. and Gergen, J. P. (1990). The Drosophila segmentation gene runt encodes a novel nuclear regulatory protein that is also expressed in the developing nervous system. Genes Dev. 4, 1701-1713.
32. Klaes, A., Menne, T., Stollewerk, A., Scholz, H. and Klambt, C. (1994). The Ets transcription factors encoded by the Drosophila gene pointed direct glial cell differentiation in the embryonic CNS. Cell 78, 149-160.
33. Lin, D. M., Auld, V. J. and Goodman, C. S. (1995). Targeted neuronal cell ablation in the Drosophila embryo: pathfinding by follower growth cones in the absence of pioneers. Neuron 14, 707-715.
34. Mellerick, D. M., Kassis, J. A., Zhang, S. D., Odenwald, W. F. (1992). castor encodes a novel zinc finger protein required for the development of a subset of CNS neurons in Drosophila. Neuron 9, 789-803.
35. Miroux, B. and Walker, J. E. (1996). Over-production of proteins in Escherichia coli: mutant hosts that allow synthesis of some membrane proteins and globular proteins at high levels. J. Mol. Biol. 260, 289-298.
36. Miyoshi, H., Shimizu, K., Kozu, T., Maseki, N., Kaneko, Y. and Ohki, K. (1991). t(8;21) breakpoints on chromosome 21 in acute myeloid leukaemia are clustered within a limited region of a single gene, AML1. Proc. Natl. Acad. Sci. USA 88, 10431-10434.
37. Mlodzik, M., Baker, N. E. and Rubin, G. M. (1990). Isolation and expression of scabrous, a gene regulating neurogenesis in Drosophila. Genes Dev. 4, 1848-1861.
38. Nucifora, G., Birn, D. J., Erickson, P., Gao, J., LeBeau, M. M., Drahkin, H. A. and Rowley, J. D. (1993). Detection of DNA rearrangements in the AML1 and ETO loci and of an AML1/ETO fusion mRNA in patients with t(8;21) acute myeloid leukaemia. Blood 81, 883-888.
39. Patel, N. H. (1994). Imaging neuronal subsets and other cell types in whole-mount Drosophila embryos and larvae using antibody probes. In Drosophila melanogaster: Practical Uses in Cell and Molecular Biology (ed. L. S. B. Goldstein and E. A. Fyrberg), Vol. 44, pp. 446-485. San Diego: Academic Press.
40. Patel, N. H., Schafer, B., Goodman, C. S. and Holmgren, R. (1989). The role of segment polarity genes during Drosophila neurogenesis. Genes Dev. 3, 890-904.
41. Prasher, D. C. (1995). Using GFP to see the light. Trends in Genet. 11, 320-323.
42. Robertson, H. M., Preston, C. R., Phillis, R. W., Johnson-Schlitz, D., Ben, W. K. and Engels, W. R. (1988). A stable source of P-element transposase in Drosophila melanogaster. Genetics 118, 461-470.
43. Rothberg, J. M., Hartley, D. A., Waither, Z. and Artavanis-Tsakonas, S. (1988). slit: an EGF-homologous locus of D. melanogaster involved in the development of the embryonic central nervous system. Cell 55, 1047-1059.
44. Schmidt, H., Rikert, C., Bossing, T., Vef, O., Urban, J. and Technau, G. M. (1997). The embryonic central nervous system lineages of Drosophila melanogaster - II. neuroblast lineages derived from the dorsal half of the neuroectoderm. Dev. Biol. 189, 186-204.
45. Seeger, M., Tear, G., Terres-Marco, D. and Goodman, C. S. (1993). Mutations affecting growth cone guidance in Drosophila: genes necessary for guidance toward or away from the midline. Neuron 10, 409-426.
46. Skeath, J. B., Zhang, Y., Holmgren, R., Carroll, S. B. and Doe, C. Q. (1995). Specification of neuroblast identity in the Drosophila embryonic central nervous system by gooseberry-distal. Nature 376, 427-430.
47. Van Vactor, D., Sink, H., Fambrough, D., Tsoo, R. and Goodman, C. S. (1993). Genes that control neuromuscular specificity in Drosophila. Cell 73, 1137-1153.
48. Zhang, Y., Ungar, A., Fresquez, C. and Holmgren, R. (1994). Ectopic expression of either the Drosophila gooseberry-distal or proximal gene causes alterations of cell fate in the epidermis and central nervous system. Development 120, 1151-1161.