The patched signaling pathway mediates repression of gooseberry allowing neuroblast specification by wingless during Drosophila neurogenesis

Development

Volumn 122, Issue 9, 1996, Pages 2921-2932

  Bhat, Krishna Moorthi ^a  

^a PRINCETON UNIVERSITY   (United States)

Author keywords

Gooseberry; Neuroblast; Neurogenesis; Patched; Signaling; Wingless

Indexed keywords

MEMBRANE PROTEIN; SIGNAL PEPTIDE; TRANSCRIPTION FACTOR;

ANIMAL CELL; ARTICLE; CELL SPECIFICITY; CONTROLLED STUDY; DROSOPHILA; EMBRYO; GENE EXPRESSION REGULATION; GENE MUTATION; GENE REPRESSION; NERVOUS SYSTEM DEVELOPMENT; NEUROBLAST; NEUROECTODERM; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; STEM CELL; TRANSGENE;

ANIMALS; CENTRAL NERVOUS SYSTEM; DROSOPHILA; DROSOPHILA PROTEINS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES, INSECT; IMMUNOHISTOCHEMISTRY; INSECT HORMONES; MEMBRANE PROTEINS; MOTOR NEURONS; MUTATION; PHENOTYPE; PROTO-ONCOGENE PROTEINS; RECEPTORS, CELL SURFACE; SIGNAL TRANSDUCTION;

ANIMALIA;

EID: 0029793645     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (34)

1. Bate, C. M. (1976). Embryogenesis of an insect nervous system. I. A map of the thoracic and abdominal neuroblasts in Locusta migratoria. J. Embryol. Exp. Morph. 35, 107-123.
2. Baumgartner, S., Bopp, D., Burri, M. and Noll, M. (1987). Structure of two genes at the gooseberry locus related to the paired gene and their spatial expression during Drosophila embryogenesis. Genes Dev. 1, 1247-1267.
3. Bejsovec, A. and Wieschaus, E. (1993). Segment polarity gene interactions modulate epidermal patterning in Drosophila embryos. Development 119, 501-517.
4. Bhat, K. M. and Schedl. P. (1994). The Drosophila mitimere gene a member of the POU family is required for the specification of the RP2/sibling lineage during neurogenesis. Development 120, 1501-1519.
5. Bhat, K. M., Poole, S. J. and Schedl, P. (1995). mitimere and pdm1 genes collaborate during specification of the RP2/sib lineage in Drosophila neurogenesis. Mol. Cell. Biol. 15, 4052-4063.
6. Bhat, K. M., Farkas, G., Karen, F., Gyurkovichs, H., Gausz, J. and Schedl, P. (1996). The GAGA factor is required in the early Drosophila embryo not only for transcriptional regulation but also for nuclear division. Development, in press.
7. Bopp, D., Burri, M., Baumgartner, S., Frigerio, G. and Noll, M. (1986). Conservation of a large protein domain in the segmentation gene paired and functionally related genes of Drosophila. Cell 47, 1033-1040.
8. Cabrera, C. V. (1992). The generation of cell diversity during early neurogenesis in Drosophila. Development 115, 893-901.
9. Campos-Ortega, J. A. (1993) The Development of Drosophila melanogaster (ed. M. Bate and A. Martinez-Arias). vol 2, pp. 1091-1129. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press
10. Chu-LaGraff, Q., and Doe, C. Q. (1993). Neuroblast specification and formation regulated by wingless in the Drosophila CNS. Science 261, 1594-1597.
11. Chu-LaGraff, Q., Schmid, A., Leidel, J., Bronner, G., Jackle, H. and Doe, C. Q. (1995). huckebein specifies aspects of CNS precursor identity required for motoneuron axon path finding. Neuron 15, 1041-1051.
12. Doe, C. Q. (1992). Molecular markers for identified neuroblasts and ganglion mother cells in the Drosophila central nervous system. Development 116, 855-863.
13. Doe, C. Q., Hiromi, Y., Gehring, W. J., and Goodman, C. S. (1988). Expression and function of the segmentation gene fushi tarazu during Drosophila neurogenesis. Science 239, 170-175.
14. Fujita, S. C., Zipursky S. L., Benzer, S., Ferrus, A., and Shotwell, S. L. (1982). Monoclonal antibodies against the Drosophila nervous system. Proc. Natl. Acad. Sci. USA 79, 7929-7933.
15. Gutjahr, T., Patel, N., Li, X., Goodman, C.S. and Noll, M. (1993). Analysis of the gooseberry locus in Drosophila embryos: gooseberry determines the cuticular pattern and activates gooseberry neuro. Development 118, 21-31.
16. Hartenstein, V. and Campos-Ortega, J. A. (1984). Early neurogenesis in wild type Drosophila melanogaster. Wilhelm Roux's Arch. Dev. Biol. 193, 308-325.
17. Hooper, J. E. (1995). Distinct pathways for autocrine and paracrine wingless signaling in Drosophila embryos. Nature 372, 461-464.
18. Hooper, J. E. and Scott, M. P. (1989). The Drosophila patched gene encodes a putative membrane protein required for segmental patterning. Cell 59, 751-765.
19. Klingensmith, J. and Nusse, R. (1994). Signaling by wingless in Drosophila. Dev. Biol. 166, 396-414.
20. Li, X. and Noll, M. (1993). Role of gooseberry gene in Drosophila embryos: maintenance of wingless expression by a wingless-gooseberry autoregulatory loop. EMBO J. 12, 4499-4509.
21. Li, X. and Noll, M. (1994). Evolution of distinct developmental functions of three Drosophila genes by acquisition of different cis-regulatory regions. Nature 367, 83-87.
22. Lindsley, D. L. and Zimm, G. G. (1992). The Genome of Drosophila melanogaster. San Diego, California: Academic Press.
23. Martinez Arias, A. (1994). Pathways of cell communication during development:signalling and epistases. Trends Genet. 10, 219-222.
24. Nakano, Y., Guerrero, I., Hidalgo, A., Taylor, A. M., Whittle, J. R. S. and Ingham, P. W. (1989). The Drosophila segment polarity gene patched encodes a protein with multiple potential membrane spanning domains. Nature 341, 508-513.
25. Noordermeer, J., Johnson, P., Rijseqijk, F., Nusse, R. and Lawrence, P. (1992). The consequences of ubiquitous expression of the wingless gene in the Drosophila embryos. Development 116, 711-719.
26. Noordermeer, J., Klingensmith, J., Perrimon, N. and Nusse, R. (1994). dishevelled and armadillo are essential components of the wingless signaling pathway in Drosophila, Nature 367, 80-83.
27. Patel, N. H., Schafer, B., Goodman, C. S. and Holmgren, R. (1989). The role of segment polarity genes during Drosophila neurogenesis. Genes Dev. 3, 890-904.
28. Schuske, K., Hooper, J. E. and Scott, M. P. (1994). patched overexpression causes loss of wingless expression in Drosophila embryos. Dev. Biol. 164, 300-311.
29. Siegfried, S., Wilder, E.L. and Perrimon, N. (1994). Components of wingless signaling in Drosophila. Nature 367, 76-80.
30. Skeath, J. B., Zhang, Y., Holmgren, R., Carroll, S. B. and Doe, C. Q. (1995) Specification of neuroblasts identity in the Drosophila embryonic central nervous system by the gooseberry-distal gene. Nature 376, 427-430.
31. Tautz, D. and C. Pfeifle (1989). A non radioactive in situ hybridization method for the localization of specific RNAs in Drosophila embryos reveals a translational control of the segmentation gene hunchback. Chromosoma 98, 81-85.
32. Thomas, J. B., Bastiani, M. J., Bate, M. and Goodman, C. S. (1984). From grasshopper to Drosophila: a common plan for neuronal development. Nature 310, 203-207.
33. Wieschaus, E. and Nusslein-Volhard, C. (1986). Looking at Embryos. In Drosophila a Practical Approach (ed. D. B. Roberts), pp 199-207. Oxford, Washington DC:IRL Press.
34. Zhang, Y., Ungar, A., Fresquez, C. and Holmgren, R. (1994). Ectopic expression of either the Drosophila gooseberry-distal or proximal gene causes alterations of cell fate in the epidermis and central nervous system. Development 120, 1151-1161.