Medial smooth muscle cell loss in arterial allografts occurs by cytolytic cell induced apoptosis

European Journal of Cardio-thoracic Surgery

Volumn 14, Issue 1, 1998, Pages 89-97

  Hirsch, Gregory M ^a   Kearsey, Joy ^a   Burt, Trevor ^a   Karnovsky, Morris J ^b   Lee, Timothy ^a  

^a DALHOUSIE UNIVERSITY   (Canada)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Allograft; Apoptosis; Artery; Chronic rejection; Fas ligand; Granzyme B; Perforin; TNF

Indexed keywords

FAS LIGAND; GRANZYME B; PERFORIN;

ANIMAL TISSUE; APOPTOSIS; ARTERY GRAFT; ARTERY INTIMA PROLIFERATION; ARTERY MUSCLE; ARTICLE; CONTROLLED STUDY; CYTOLYSIS; GRAFT REJECTION; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; APOPTOSIS; ARTERIES; FEMORAL ARTERY; IMMUNOHISTOCHEMISTRY; POLYMERASE CHAIN REACTION; RATS; RATS, INBRED BN; RATS, INBRED F344; RATS, INBRED LEW; TUNICA MEDIA;

EID: 0031830054     PISSN: 10107940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1010-7940(98)00131-6     Document Type: Article

References (20)

1. Isik F.F., McDonald T.O., Ferguson M., Yamanaka E., Gordan D. Transplant arteriosclerosis in a rat aortic model. Am J Pathol. 141:1992;1139-1149.
2. Menander A., Tilsala S., Paavonen T., Halttunen J., Hayry P. Chronic rejection of rat aortic allografts. An experimental model for transplant arteriosclerosis. Arterioscler Thromb. 11(3):1991;671-680.
3. Demetrus A.J., Zerbe T., Banner B. Morphology of solid organ allograft arteriopathy: identification of proliferating intimal cell populations. Transplant Proc. 21:1989;3667-3669.
4. Billingham B.E. Histopathology of graft coronary disease. J Heart Lung Transplant. 12:1992;538-544.
5. Reidy M.A. Biology of disease, a reassessment of endothelial injury and arterial lesion formation. Lab Invest. 53:1985;513-520.
6. Plissonnier D., Nochy D., Poncet P., Chantal M., Hinglais N., Bariety J., Michel J. Sequential immunological targeting of chronic experimental arterial allografts. Transplantation. 60(5):1995;414-424.
7. Alpiprantis A., Diex-Roux G., Mulder L., Zychlinsky A., Lang R. Do macrophages kill by apoptosis? Immunol Today. 17:1996;573-576.
8. Schroter M., Lowin B., Borner C., Tschopp J. Regulation of Fas (Apo-1 /CD95)- and perforin mediated lytic pathways of primary cytotoxic T lymphocytes by the protooncogene bc1-2. Eur J Immunol. 25:1995;3509-3513.
9. Uren A.M., Vauz D. Molecular and clinical aspects of apoptosis. Pharmacol Ther. 72:1996;37-50.
10. Adarms D.H., Tilney N.L., Colins J.J., Karnovsky M.J. Experimental graft arteriosclerosis, I: the Lewis to F 344 allograft model. Transplantation. 53:1992;1115-1119.
11. Perlman H., Maiilard L., Krasinski K., Walsh K. Evidence for the rapid onset of apoptosis in medial smooth muscle cells after balloon injury. Circulation. 95(4):1996;981-987.
12. Gavrielli Y., Shermany Y., Ben Sasson S.A. Identification of programmed cell death in situ labeling of nuclear DNA fragmentation. J Cell Biol. 119(3):1992;493-501.
13. Fishman J.A., Ryan G.B., Karnovsky M.J. Endothelial regeneration in the rat carotid artery and the significance of endothelial denudation on the pathogenesis of myointimal thickening. Lab Invest. 32:1975;339-351.
14. Bergese S.D., Klenotic S.M., Wakely E.M., Sedmak D., Orosz G. Apoptosis in murine cardiac grafts. Transplantation. 63:1997;320-325.
15. Krams S.M., Egawa H., Quinn M.B., Villanueva J., Garcia-Kennedy R., Martinez O. Apoptosis as a mechanism of cell death in liver allograft rejection. Transplantation. 59:1995;621-625.
16. Zheng L., Fisher G., Miller R., Peschon J., Lynch D., Lenardo M. Induction of apoptosis in mature T cells by tumour necrosis factor. Nature. 377:1995;348-351.
17. Miura M., Friedlander R., Yung J. Tumor necrosis factor induced apoptosis is mediated by a CrmA-sensitive cell death pathway. Proc Natl Acad Sci USA. 92:1995;8318-8322.
18. Lowin B., Beerman F., Schmidt A., Tschopp J. A null mutation in the perforin gene abolishes cytolytic T lymphocyte and NK-mediated cytotoxicity. Proc Natl Acad Sci USA. 91:1994;11571-11575.
19. Zhivotovsky B., Burgess D.H., Orrenius S. Proteases in apoptosis. Experientia. 52:1996;968-978.
20. Hahn S., Gehri R., Erb P. Mechanism and biological significance of CD4-mediated cytotoxicity. Immunol Rev. 146:1995;57-79.