Ovariectomy causes cell proliferation and matrix synthesis in the growth plate cartilage of the adult rat

Histochemical Journal

Volumn 30, Issue 7, 1998, Pages 467-472

  Tajima, Yoshifumi ^a   Yokose, Satoshi ^a   Kawasaki, Mina ^a   Takuma, Taishin ^b  

^a MEIKAI UNIVERSITY SCHOOL OF DENTISTRY   (Japan)

^b HEALTH SCIENCES UNIVERSITY OF HOKKAIDO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CHONDROITIN SULFATE; CYCLINE; PROTEOGLYCAN; SOMATOMEDIN C;

ANIMAL CELL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ARTICLE; CARTILAGE; CELL PROLIFERATION; CONTROLLED STUDY; FEMALE; GROWTH PLATE; HORMONE BLOOD LEVEL; IMAGE ANALYSIS; IMMUNOHISTOCHEMISTRY; NONHUMAN; OVARIECTOMY; PRIORITY JOURNAL; QUANTITATIVE DIAGNOSIS; RAT;

ANIMALS; BODY WEIGHT; BONE MATRIX; CELL DIFFERENTIATION; CELL DIVISION; CHONDROCYTES; ESTROGENS; FEMALE; GROWTH HORMONE; GROWTH PLATE; IMAGE CYTOMETRY; IMMUNOHISTOCHEMISTRY; INSULIN-LIKE GROWTH FACTOR I; ORGAN SIZE; OVARIECTOMY; PROLIFERATING CELL NUCLEAR ANTIGEN; PROTEOCHONDROITIN SULFATES; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0031828042     PISSN: 00182214     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1003212023853     Document Type: Article

References (23)

1. AERSSENS, J., AUDEKERCKE, R.V., GEUSENS, P., SCHOT, L.P.C., OSMAN, A.A-H. & DEQUEKER, J. (1993) Mechanical properties, bone mineral content, and bone composition (collagen, osteocalcin, IGF-I) of the rat femur: influence of ovariectomy and nandrolone decanoate (anabolic steroid) treatment. Calcif. Tissue Int. 53, 269-77.
2. BAGl, C.M., MECHAM, M., WEISS, J. & MILLER, S.C. (1993) Comparative morphometric changes in rat cortical bone following ovariectomy and/or immobilization. Bone 14, 877-83.
3. BAXTER, R.C. (1993) Circulating binding proteins for the insulin-like growth factors. Trends Endocrinol. Metabol. 4, 91-6.
4. BERELOWITZ, M., SZABO, M., FROHMAN, L.A., FIRESTONE, S., CHU, L. & HINTZ, R.L. (1981) Somatomedin-C mediates growth hormone negative feedback by effects on both the hypothalamus and the pituitary. Science 212, 1279-81.
5. BLUM, W.F., JENNE, E.W., REPPIN, F., KIETZMANN, K., RANKE, M.B. & BlERlCH, J.R (1989) Insulin-like growth factor I (IGF-I)-binding protein complex is a better mitogen than free IGF-I. Endocrinology 125, 766-72.
6. DAUGHADAY, W.H. & ROTWEIN, P. (1989) Insulin-like growth factors I and II. Peptide, messenger ribonucleic acid and gene structures, serum, and tissue concentrations. Endocrine Rev. 10, 68-91.
7. HASCALL, V.C., HANDLEY, C.J., McQUILLAN, D.J., HASCALL, G.K., ROBINSON, H.C. & LOWTHER, D.A. (1983) The effect of serum on biosynthesis of proteoglycans by bovine articular cartilage in culture. Arch. Biochem. Biophys. 224, 206-23.
8. HILL, D.J. (1979) Stimulation of cartilage zones of the calf costochondral growth plate in vitro by growth hormone dependent rat plasma somatomedin activity. J. Endocrinol. 83, 219-27.
9. HOLLY, J.M.P. & MARTIN, J.L. (1994) Insulin-like growth factor binding proteins: a review of methodological aspects of their purification, analysis and regulation. Growth Regul. 4, 20-30.
10. HUNZIKER, E.B., WAGNER, J. & ZAPF, J. (1994) Differential effects of insulin-like growth factor I and growth hormone on developmental stages of rat growth plate chondrocytesin in vivo. J. Clin. Invest. 93, 1078-86.
11. KALU, D N. (1991) The ovariectomized rat model of postmenopausal bone loss. Bone Miner. 15, 175-92.
12. KALU, D.N., ARJMANDI, B.H., LIU, C-C., SALIH, M.A. & BIRNBAUM, R.S. (1994) Effects of ovariectomy and estrogen on the serum levels of insulin-like growth factor-I and insulin-like growth factor binding protein-3. Bone Miner. 25, 135-48.
13. LEBOVITZ, H.E. & EISENBARTH, G.S. (1975) Hormonal regulation of cartilage growth and metabolism. In: Vitamins and Hormones, Vol. 33 (edited by MUNSON, P.L., DICZFALUSY, E., GLOVER, J. & OLSON, R.E.), pp. 575-648. New York: Academic Press.
14. McQUIlLLAN, D.J., HANDLEY, C.J., CAMPBELL, M.A., BOLIS, S., MILWAY, V.E. & HERINGTON, A.C. (1986) Stimulation of proteoglycan biosynthesis by serum and insulin-like growth factor-I in cultured bovine articular cartilage. Biochem. J. 240, 423-30.
15. PALMER, R.M., LOVERIDGE, N., THOMSON, B.M., MACKIE, S.C., TONNER, E. & FLINT, D.J. (1994) Effects of a polyclonal antiserum to rat growth hormone on circulating insulin-like growth factor (IGF)-I and IGF-binding protein concentrations and the growth of muscle and bone. J. Endocrinol. 142, 85-91.
16. SATO, F., OUCHl, Y., MASUYAMA, A., NAKAMURA, T., HOSOI, T., OKAMOTO, Y., SASAKI, N., SHIRAKI, M. & ORIMO, H. (1993) Effects of estrogen replacement on insulin-like growth factor I concentration in serum and bone tissue and on interleukin 1 secretion from spleen macrophages in oophorectomized rats. Calcif. Tissue Int. 53, 111-16.
17. SPENCER, E.M., LIU, C.C., SI, E.C.C. & HOWARD, G,.A. (1991) In vivo actions of insulin-like growth factor-I (IGF-I) on bone formation and resorption in rats. Bone 12, 21-6.
18. TAJlMA, Y., KATO, K., MARUYAMA, S. & HOSOI, K. (1996) In vivo modulation of proliferating cell nuclear antigen in growth plate chondrocytes from normal, hypophysectomized, and growth hormone-treated hypophysectomized rats: a comparative immunohistochemical study with image analysis. J. Histochem. Cytochem. 44, 713-20.
19. VERSCHURF, P.J., VAN NOORDEN, C.J.F., VAN MARLE, J. & VAN DEN BERG, W.B. (1996) Articular cartilage destruction in experimental inflammatory arthritis: insulin-like growth factor-1 regulation of proteoglycan metabolism in chondrocytes. Histochem. J. 28, 835-57.
20. WRONSKl, T.J., WALSH, C.C. & IGNASZEWSKI, L.A. (1986) Histologic evidence for osteopenia and increased bone turnover in ovariectomized rats. Bone 7, 119-23.
21. WRONSKI, T.J., CINTRON, M. & DANN, L.M. (1988) Temporal relationship between bone loss and increased bone turnover in ovariectomized rats. Calcif. Tissue Int. 43, 179-83.
22. YAMAMURA, M., NAKAMURA, T., TSURUKAMI, H., HIJIOKA, A., NARUSAWA, K., OHNISHI, H., OHTA, T. & HOSODA, K. (1996) Local bone turnover in the metaphysis of the proximal tibia and the lumbar vertebra during the early periods after ovariectomy in rats. Calcif Tissue Int. 58, 52-9.
23. YOKOSE, S., ISHIZUYA, T., IKEDA, T., NAKAMURA, T., TSURUKAMI, H., KAWASAKI, K., SUDA, T., YOSHIKI, S. & YAMAGUCHI, A. (1996) An estrogen deficiency caused by ovariectomy increases plasma levels of systemic factors that stimulate proliferation and differentiation of osteoblasts in rats. Endocrinology 137, 469-78.