An estrogen deficiency caused by ovariectomy increases plasma levels of systemic factors that stimulate proliferation and differentiation of osteoblasts in rats

Endocrinology

Volumn 137, Issue 2, 1996, Pages 469-478

  Yokose, Satoshi ^a   Ishizuya, Toshinori ^a,b   Ikeda, Tohru ^a   Nakamura, Toshitaka ^c   Tsurukami, Hiroshi ^c   Kawasaki, Kojiro ^a,d   Suda, Tatsuo ^a   Yoshiki, Shusaku ^a   Yamaguchi, Akira ^a  

^a SHOWA UNIVERSITY   (Japan)

^b ASAHI CHEMICAL INDUSTRY CO   (Japan)

^c UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

^d KAGAWA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PHOSPHATASE; CALCIUM; DNA; ESTRADIOL; ESTROGEN; INTERLEUKIN 1; INTERLEUKIN 6; MESSENGER RNA; OSTEOCALCIN; SOMATOMEDIN C;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; DNA CONTENT; ESTROGEN DEFICIENCY; FEMALE; HORMONAL REGULATION; NEWBORN; NONHUMAN; OSSIFICATION; OSTEOBLAST; OVARIECTOMY; PATHOGENESIS; PRIORITY JOURNAL; RAT; SUBCUTANEOUS DRUG ADMINISTRATION;

EID: 0030065159     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.137.2.8593791     Document Type: Article

References (55)

1. Wronski TJ, Cintron M, Dann LM 1988 Temporal relationship between bone loss and increased bone turnover in ovariectomized rats. Calcif Tissue Int 43:179-183
2. Boyce RW, Franks AF, Jankowsky ML, Orcutt CM, Piacquadio AM, White JM, Bevan JA 1990 Sequential histomorphometric changes in cancellous bone from ovariohysterectomized dogs. J Bone Miner Res 5:947-953
3. Balena R, Toolan BC, Shea M, Markatos A, Myers ER, Lee SC, Opas EE, Seedor JG, Klein H, Frankenfield D, Quartuccio H, Fioravanti C, Clair J, Brown E, Hayes WC, Rodan A 1993 The effects of 2-year treatment with the aminobisphosphonate alendronate on bone metabolism, bone histomorphometry, and bone strength in ovariectomized nonhuman primates. J Clin Invest 92:2577-2586
4. Parfitt AM, Kleerekoper M 1984 Diagnostic value of bone histomorphometry and comparison of histologic measurements and biochemical indices of bone remodeling. In: Christiansen C, Arnaud CD, Nordin BEC, Parfitt AM, Peck WA, Riggs BL (eds) Osteoporosis. Glostrup Hospital, Denmark, pp 111-120
5. Eriksen EF, Hodgson SF, Eastell R, Cedel SL, O'Fallon WM, Riggs BL 1990 Cancellous bone remodeling in type I (postmenopausal) osteoporosis: quantitative assessment of rates of formation, resorption, and bone loss at tissue and cellular levels. J Bone Miner Res 5:311-319
6. Johnston CC, Hui SL, Witt RM, Appledorn R, Baker RS, Longcope C 1985 Early menopausal changes in bone mass and sex steroids. J Clin Endocrinol Metab 61:905-911
7. Pacifici R, Rifas L, Mccracken R, Vered I, Mcmurtry C, Avioli LV, Peck WA 1989 Ovarian steroid treatment blocks a postmenopausal increase in blood monocyte interleukin 1 release. Proc Natl Acad Sci USA 86:2398-2402
8. Kimble RB, Vannice JL, Bloedow DC, Thompson RC, Hopfer W, Kung VT, Brownfield C, Pacifici R 1994 Interleukin-1 receptor antagonist decreases bone loss and bone resorption in ovariectomized rats. J Clin Invest 93:1959-1967
9. Kitazawa R, Kimble RB, Vannice JL, Kung VT, Pacifici R 1994 Interleukin-1 receptor antagonist and tumor necrosis factor binding protein decrease osteoclast formation and bone resorption in ovariectomized mice. J Clin Invest 94:2397-2406
10. Jilka RL, Hangoc G, Girasole G, Passen G, Williams DC, Abrams JS, Boyce B, Broxmeyer H, Manolagas SC 1992 Increased osteoclast development after estrogen loss: mediation by interleukin-6. Science 257:88-91
11. Passeri G, Girasole G, Jilka R, Manolagas SC 1993 Increased interleukin-6 production by murine bone marrow and bone cells after estrogen withdrawal. Endocrinology 133:822-828
12. Manolagas SC, Jilka RL, Girasole G, Passeri G, Bellido T 1993 Estrogen, cytokines, and the control of osteoclast formation and bone resorption in vitro and in vivo. Osteoporosis Int [Suppl] 1:S114-116
13. Poli V, Balena R, Fattori E, Markatos A, Yamamoto M, Tanaka H, Ciliberto G, Rodan G A, Costantini F 1994 Interleukin-6 deficient mice are protected from bone loss caused by estrogen depletion. EMBO J 13:1189-1196
14. Sato F, Ouchi Y, Masuyama A, Nakamura T, Hosoi T, Okamoto Y, Sasaki N, Shiraki M, Orimo H 1993 Effects of estrogen replacement on insulin-like growth factor I concentrations in serum and bone tissue and on interleukin 1 secretion from spleen macrophages in oophorectomized rats. Calcif Tissue Int 53:111-116
15. Kalu D N, Arjmandi BH, Liu C-C, Salih MA, Birnbaum RS 1994 Effects of ovariectomy and estrogen on the serum levels of insulin-like growth factor-I and insulin-like growth factor binding protein-3. Bone Miner 25:135-148
16. Canalis E, Lian JB 1988 Effects of bone associated growth factors on DNA, collagen and osteocalcin synthesis in cultured fetal rat calvariae. Bone 9:243-246
17. McCarthy TL, Centrella M, Canalis E 1989 Regulatory effects of insulin-like growth factors I and II on bone collagen synthesis in rat calvarial cultures. Endocrinology 124:301-309
18. Spencer EM, Liu CC, Si ECC, Howard GA 1991 In vivo actions of insulin-like growth factor-I (IGF-I) on bone formation and resorption in rats. Bone 12:21-26
19. Mueller K, Cortesi R, Modrowski D, Marie PJ 1994 Stimulation of trabecular bone formation by insulin-like growth factor I in adult ovariectomized rats. Am J Physiol 267:E1-E6
20. Machwate M, Zerath E, Holy X, Pastoureau P, Marie PJ 1994 Insulin-like growth factor-I increases trabecular bone formation and osteoblastic cell proliferation in unloaded rats. Endocrinology 134: 1031-1038
21. Mochizuki H, Hakeda Y, Wakatsuki N, Usui N, Akashi S, Sato T, Tanaka K, Kumegawa M 1992 Insulin-like growth factor-I supports formation and activation of osteoclasts. Endocrinology 131:1075-1080
22. Slootweg MC, Most W M, Beck E, Schot LPC, Papapoulos SE, Lowik CWGM 1992 Osteoclast formation together with interleukin-6 production in mouse long bones is increased by insulin-like growth factor-I. J Endocrinol 132:433-438
23. Wong GL, Kotliar D, Schlaeger D, Brandes SJ 1990 IGF-I production by mouse osteoblasts. J Bone Miner Res 5:133-140
24. Centrella M, McCarthy TL, Canalis E 1990 Receptors for insulin-like growth factors-I and II in osteoblast-enriched cultures from fetal rat bone. Endocrinology 126:39-44
25. Simmons DJ, Kent GN, Jilka RL, Scott DM, Fallon M, Cohn DV 1982 Formation of bone by isolated, cultured osteoblasts in millipore diffusion chambers. Calcif Tissue Int 34:291-294
26. Bab I, Ashton BA, Syftestad GT, Owen ME 1984 Assessment of an in vivo diffusion chamber method as a quantitative assay for osteogenesis. Calcif Tissue Int 36:77-82
27. Ashhurst DE, Ashton BA, Owen ME 1990 The collagens and glycosaminoglycans of the extracellular matrices secreted by bone marrow stromal cells cultured in vivo in diffusion chambers. J Ortho Res 8:741-749
28. Wong G 1990 Isolation and behavior of isolated bone-forming cells. In: Hall K (ed) The osteoblast and osteocyte. Bone, vol 1. The Telford Press, Caldwell, New Jersey, pp 171-192
29. Rodan GA, Heath JK, Yoon K, Noda M, Rodan SB 1988 Diversity of the osteoblastic phenotype. In: Evered D, Harnett S (eds) Cell and Molecular Biology of Vertebrate Hard Tissues. A Wiley-Interscience Publication, Chichester, New York, pp 78-91
30. Hauschka PV 1990 Growth factor effects in bone. In: Hall BK (eds) The osteoblast and osteocyte. Bone, vol 1. The Telford Press, Caldwell, New Jersey, pp 103-170
31. Stein GS, Lian JB 1993 Molecular mechanisms mediating developmental and hormone-regulated expression of genes in osteoblast: an integrated relationship of cell growth and differentiation. In: Noda M (ed) Cellular and molecular biology of bone. Academic Press, San Diego, pp 47-95
32. Partridge NC, Alcorn D, Michelangeli VP, Kemp BE, Ryan GB, Martin TJ 1981 Functional properties of hormonally responsive cultured normal and malignant rat osteoblastic cells. Endocrinology 108:213-219
33. Murakami H, Nakamura T, Tsurukami H, Abe M, Barbier A, Suzuki K 1994 Effects of tiludronate on bone mass, structure, and turnover at the epiphyseal, primary, and secondary spongiosa in the proximal tibia of growing rats after sciatic neurectomy. J Bone Miner Res 9:1355-1364
34. Parfitt AM, Drezner MK Glorieux FH, Kanis JA, Malluche H, Meunier PJ, Ott SM, Recker RR 1987 Bone histomorphometry: standardization of nomenclature, symbols, and units. J Bone Miner Res 6:595-610
35. Kissane JM, Robins E 1958 The fluorometric measurement of deoxyribonucleic acid in animal tissues with special reference to the central nervous system. J Biol Chem 233:184-195
36. Noda M, Yoon K, Thiede M, Buenaga R, Weiss M, Henthorn P, Harris H, Rodan GA 1987 cDNA cloning of alkaline phosphatase from rat osteosarcoma (ROS 17/2.8) cells. J Bone Miner Res 2:161-164
37. Celeste AJ, Rosen V, Buecker JL, Kriz R, Wang EA, Wozney JM 1986 Isolation of the human gene for bone gla protein utilizing mouse and rat cDNA clones. EMBO J 5:1885-1890
38. Daughaday WH, Mariz IK, Blethen SL 1980 Inhibition of access of bound somatomedin to membrane receptor and immunobinding sites: a comparison of radioreceptor and radioimmunoassay of somatomedin in native and acid- ethanol-extracted serum. J Clin Endocrinol Metab 51:781-788
39. Manolagas SC, Jilka RL 1995 Bone marrow, cytokines, and bone remodeling. Emerging insights into the pathophysiology of osteoporosis. New Engl J Med 332:305-311
40. Chow J, Tobias H, Colston KW, Chambers TJ 1992 Estrogen maintains trabecular bone volume in rats not only by suppression of bone resorption but also by stimulation of bone formation. J Clin Invest 89:74-78
41. Westerlind KC, Wakley GK, Evans GL, Turner RT 1993 Estrogen dose not increase bone formation in growing rats. Endocrinology 133:2924-2934
42. Keeting PE, Scott RE, Colvard DS, Han IK, Spelsberg TC, Riggs BL 1991 Lack of a direct effect of estrogen on proliferation and differentiation of normal human osteoblast-like cells. J Bone Miner Res 6:297-304
43. Prior JC 1990 Progesterone as a bone-trophic hormone. Endocr Rev 11:386-398
44. Barengolts EI, Lathon PV, Lindh FG 1995 Progesterone antagonist RU 486 has bone-sparing effects in ovariectomized rats. Bone 17: 21-25
45. Slootweg MC, Ederveen AGH, Schot LPC, Schoonen WGEJ, Kloosterboer HJ 1992 Oestrogen and progestogen synergistically stimulate human and rat osteoblast proliferation. J Endocrinol 133: R5-R8
46. McCarthy TL, Centrella M, Canalis E 1989 Parathyroid hormone enhances the transcript and polypeptide levels of insulin-like growth factor I in osteoblast- enriched cultures from fetal rat bone. Endocrinology 124:1247-1253
47. Chen TL, Liu F, Bates RL, Hintz RL 1991 Further characterization of insulin-like-growth factor binding proteins in rat osteoblast-like cell cultures: modulation by 17 β- estradiol and human growth hormone. Endocrinology 128:2489-2496
48. 3. Endocrinology 128:1511-1518
49. Kalu DN 1991 The ovariectomized rat model of postomenopausal bone loss. Bone Miner 15:175-192
50. Schwander JC, Hauri C, Zapf J, Froesch ER 1983 Synthesis and secretion of insulin-like growth factor and its binding protein by the perfused rat liver: dependence on growth hormone status. Endocrinology 113:297-305
51. Watson P, Lazowski D, Han V, Fraher L, Steer B, Hodsman A 1995 Parathyroid hormone restores bone mass and enhances osteoblast insulin-like growth factor I gene expression in ovariectomized rats. Bone 16:357-365
52. Lalou C, Silve C, Rosata R, Segovia B 1994 Interactions between insulin-like growth factor-I (IGF-I) and the system of plasminogen activators and their inhibitors in the control of IGF-binding protein-3 production and proteolysis in human osteosarcoma cells. Endocrinology 135:2318-2326
53. Pacifici R, Rifas L, Teitelbaum S, Slatopolsky E, McCracken R, Bergfeld M, Lee W, Avioli LV, Peck WA 1987 Spontaneous release of interleukin 1 from human blood monocytes reflects bone formation in idiopathic osteoporosis. Proc Natl Acad Sci USA 84:4616-4620
54. Stashenko P, Obernesser MS, Dewhirst FE 1989 Effects of immune cytokines on bone. Immunol Invest 18:239-249
55. Hughes FJ, Howells GL 1993 Interleukin-6 inhibits bone formation in vitro. Bone Miner 21:21-28