Wound reepithelialization activates a growth factor-responsive enhancer in migrating keratinocytes

FASEB Journal

Volumn 12, Issue 11, 1998, Pages 959-969

  Jaakkola, Panu ^a   Kontusaari, Sirpa ^b   Kauppi, Tuire ^b   Määttä, Arto ^c   Jalkanen, Markku ^d  

^a UNIVERSITY OF TURKU   (Finland)

^b UNIVERSITY OF OULU   (Finland)

^c IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^d TURKU CENTRE FOR BIOTECHNOLOGY   (Finland)

Author keywords

EGF; FiRE; Migration; Syndecan 1; TGF ; Transcription

Indexed keywords

FIBROBLAST GROWTH FACTOR; SYNDECAN;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL MIGRATION; ENHANCER REGION; EPITHELIZATION; FEMALE; GENE EXPRESSION; KERATINOCYTE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; STIMULATION; WOUND HEALING;

ANIMALIA; MUS MUSCULUS;

EID: 0031827748     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fasebj.12.11.959     Document Type: Article

References (40)

1. Woodley, D. T. (1996) in The Molecular and Cellular Biology of Wound Repair (Clark, R. A. F., ed) 2nd Ed, pp. 339-354, Plenum, New York
2. Martin, P. (1997) Wound healing-aiming for perfect skin regeneration. Science 276, 75-81
3. Marchesc, C., Cheddid, M., Dirch, O. R., Csaky, K. G., Santanelli, F., Latini, C., LaRocelle, W. J., Torrisi, M. R., and Aaronson, S. A. (1995) Modulation of keratinocyte growth factor and its receptor in reepithelializing human skin. J. Exp. Med. 182, 1369-1376
4. Gallo, R., Kim, C., Kokenyesi, R., Adzick, N. S., and Bernfield, M. (1996) Syndecans-1 and -4 are induced during wound repair of neonatal but not fetal skin. J. Invest. Dermatol. 107, 676-683
5. Elenius, K., Vainio, S., Laato, M., Salmivirta, M., Thesleff, I., and Jalkanen, M. (1991) Induced expression of syndecan in healing wounds. J. Cell Biol. 114, 585-595
6. Marshall, G. M., Vanhamme, L., Wong, W. Y., Su, Y., and Vogt, P. K. (1992) Wounding acts as a tumor promoter in chickens inoculated with avian sarcoma virus 17. Virology 188, 373-377
7. Martin, P., and Nobes, C. (1992) An early molecular component of the wound healing response in rat embryos - induction of c-fos protein in cells at the epidermal wound margin. Mech. Dev. 38, 209-215
8. Bennet, N., and Schultz, G. (1993) Growth factors and wound healing: biochemical properties of growth factors and their receptors. Am. J. Surg. 165, 728-737
9. Nanney, L. B., and King, L. E., Jr. (1996) The Molecular and Cellular Biology of Wound Repair (Clark, R. A. F., ed) 2nd Ed, pp. 171-194, Plenum, New York
10. Basilico, C., and Moscatelli, D. (1992) The FGF family of growth factors and oncogenes. Adv. Cancer Res. 59, 115-165
11. Tsuboi, R., Sato, C., Kurita, Y., Ron, D., Rubin, J. S., and Ogawa, H. (1993) Keratinocyte growth factor (FGF-7) stimulates migration and plasminogene activator activity of normal human keratinocytes. J. Invest. Dermatol. 101, 49-53
12. Werner, S., Smola, H., Liao, X., Longaker, M., Krieg, T., Hofschneider, P. H., and Williams, L. (1994) The function of KGF in morphogenesis of epithelium and reepithelialization of wounds. Science 266, 819-822
13. Brown, G. L., Nanney, L. B., Griffen, J., Cramer, A. B., Yancey, J. M., Curtsinger, L. J., Holtzin, L., Schultz, G. S., Jurkiewicz, M. J., and Lynch, J. B. (1989) Enhancement of wound healing by topical treatment with epidermal growth factor. N. Engl. J. Med. 321, 76-79
14. Staiano-Coico, L., Krueger, J. G., Rubin, J. S., D'limi, S., Vallat, V. P., Valentino, L., Fahey, T., Hawes, A., Kingston, G., Madden, M. R., Mathwich, M., Gottlieb, A. B., and Aaronson, S. A. (1993) Human keratinocyte growth factor effects in a porcine model of epidermal wound healing. J. Exp. Med. 178, 865-878
15. Davidson, J. M., and Broadley, K. N. (1991) Manipulation of the wound-healing process with basic fibroblast growth factor. Ann. N.Y. Acad. Sci, 638, 306-315
16. Clark, R. A. F. (1996) The Molecular and Cellular Biology of Wound Repair (Clark, R. A. F., ed) 2nd Ed, pp. 3-50, Plenum, New York
17. Jaakkola, P., Vihinen, T., Määttä, A., and Jalkanen, M. (1997) Activation of an enhancer on syndecan-1 gene is restricted to the fibroblast growth factor-family members. Mol. Cell, Biol 17, 3210-3219
18. Bernfield, M., Kokenyesi, R., Kato, M., Hinkes, M. T., Spring, J., Gallo, R. L., and Lose, E. J. (1992) Biology of the syndecans: a family of transmembrane heparan sulfate proteoglycans. Annu. Rev. Cell Biol. 8, 365-393
19. Vihinen, T., Määttä, A., Jaakkola, P., Auvinen, P., and Jalkanen, M. (1996) Functional characterization of mouse syndecan-1 promoter. J. Biol. Chem. 271, 12532-12541
20. Hogan, B., Constantini, F., and Lacy, E. (1986) Manipulating the Mouse Embryo: A Laboratory Manual, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York
21. Hanley, T., and Merlie, J. P. (1991) Transgene detection in unpurified mouse tail DNA by polymerase chain reaction. Bio-Techiques 10, 56
22. Behringer, R. R., Grotty, D. A., Tennyson, V. M., Brinster, R. L., Palmiter, R. D., and Wolgemuth, D. J. (1993) Sequences 5′ of the homeobox of the Hoz-1.4 gene direct tissue-specific expression of Lac-Z during mouse development. Development 117, 823-833
23. Vihinen, T., Auvinen, P., Alanen-Kurki, L., and Jalkanen, M. (1993) Structural organization and genotnic sequence of mouse syndecan-1 gene. J. Biol. Chem. 268, 17261-17269
24. Hinkes, M. T., Goldberger, O. A., Neumann, P. E., Kokenyesi, R., and Bernfield, M. (1993) Organization and promoter activity of the mouse syndecan-1 gene. J. Biol. Chem. 268, 11440-11448
25. Takasaki, Y., Deng, J. S., and Tan, E. M. (1981) A nuclear antigen associated with cell proliferation and blast transformation: its distribution in synchronized cells. J. Exp. Med. 154, 1899-1909
26. Haynes, J. H., Krummel, T. M., Flood, L. C., Cohen, I. K., and Diegelmann, R. F. (1990) Fetal skin organ culture. J. Invest. Surg. 3, 349-355
27. Chamberlain, J., Shah, M., and Ferguson, M. W. J. (1995) The effect of suramin on healing adult rodent dermal wounds. J. Anat. 186, 87-96
28. Stoscheck, C. M., Nanney, L. B., and King, L. E. J. (1992) Quantitative determination of EGF-R during epidermal wound healing. J. Invest. Dermatol. 99, 645-649
29. Schonthal, A., Tsukitani, Y., and Feramisco, J. R. (1991) Transcriptional and post-transcriptional regulation of c-fos expression by the tumor promoter okadaic acid. Oncogene 6, 423-430
30. Kulesz-Martin, M., Kilkenny, A. E., Holbrook, K. A., Digernes, V., and Yuspa, S. (1983) Properties of carcinogen altered mouse epidermal cells resistant to calcium induced terminal differentiation. Carcinogenesis 4, 1367-1377
31. Alessi, D. R., Cuenda, A., Cohen, P., Dudley, D. T., and Saltiel., A. R. (1995) PD 098059 is a specifie inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo. J. Biol. Chem. 270, 27489-27494
32. Cuenda, A., Rouse, J., Doza, Y. N., Meier, R., Cohen, P., Gallagher, T. F., Young, P. R., and Lee, J. C. (1995) SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1. FEBS Lett. 364, 229-233
33. Arcaro, A., and Wymann, M. P. (1993) Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: the role of phosphatidylinositol 3,4 5-triphosphate in neutrophil responses. Biochem. J. 296, 297-301
34. Seo, S., Okamoto, M., Seto, H., Ishizuka, K., Sano, H., and Ohashi, Y. (1995) Tobacco MAP kinase: a possible mediator in wound signal transduction pathways. Science 270, 1988-1991
35. Rosenberg, G. A. (1995) Matrix metalloproteinases in brain injury. J. Neurotrauma 12, 833-842
36. Navarro, J. M., Casatorres, J., and Jorcano, J. L. (1995) Elements controlling the expression and induction of the skin hyperproliferation-associated keratin K6. J. Biol. Chem. 270, 21362-21367
37. Dlugosz, A., Cheng, C., Denning, M., Dempsey, P., Coffey, R., and Yuspa, S. (1994) Keratinocyte growth factor receptor ligands induce transforming growth factor alpha expression and activate the epidermal growth factor receptor signaling pathway in cultured epidermal keratinocytes. Cell Growth Differ. 5, 1283-1292
38. Rouse, J., Cohen, P., Trigon, S., Morange, M., Alonso-Llamazares, A., Zamanillo, D., Hunt, T., and Nebreda, A. R. (1994) A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins. Cell 78, 1027-1037
39. Cuenda, A., Cohen, P., Buee-Scherrer, V., and Goedert, M. (1997) Activation of stress-activated protein kinase-3 (SAPK3) by cytokines and cellular stresses is mediated via SAPKK3 (MKK6); comparison of the specificities of SAPK3 and SAPK2 (RK/p38). EMBO J. 16, 295-305
40. Sachsenmaier, C., Radler-Pohl, A., Zinck, R., Mordheim, A., Herrlich, P., and Rahmsdorf, H.J. (1994) Involvement of growth factor receptors in the mammalian UVC response. Cell 78, 963-972