Lymphocytic Choriomeningitis Virus-Induced Alterations of T Helper-Mediated Responses in Mice Developing Autoimmune Hemolytic Anemia during the Course of Infection

Experimental Biology and Medicine

Volumn 218, Issue 4, 1998, Pages 349-356

  El Azami El Idrissi, M ^a   Mazza, G ^b   Monteyne, P ^a   Elson, C J ^b   Day, M J ^b   Pfau, C J ^c   Coutelier, J P ^a  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^b UNIVERSITY OF BRISTOL   (United Kingdom)

^c RENSSELAER POLYTECHNIC INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY RESPONSE; AUTOIMMUNE HEMOLYTIC ANEMIA; CONFERENCE PAPER; HELPER CELL; IMMUNOPATHOGENESIS; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; VIRUS MENINGITIS;

ANEMIA, HEMOLYTIC; ANIMALS; ANTIGENS; AUTOIMMUNE DISEASES; CELL LINE; DOGS; FEMALE; HEMOCYANIN; IMMUNIZATION; KIDNEY; LYMPHOCYTE ACTIVATION; LYMPHOCYTIC CHORIOMENINGITIS; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MICE; MICE, INBRED C3H; MICE, INBRED CBA; MOLLUSCA; T-LYMPHOCYTES, HELPER-INDUCER;

ANIMALIA; CHORIOMENINGITIS VIRUS; LYMPHOCYTIC CHORIOMENINGITIS VIRUS;

EID: 0031824982     PISSN: 00379727     EISSN: None     Source Type: Journal    
DOI: 10.3181/00379727-218-44303     Document Type: Article

References (46)

1. Ahmed R, Oldstone MBA. Mechanisms and biological implications of virus-induced polyclonal B-cell activation. In: Notkins AL, Oldstone MBA, Eds. Concepts in Viral Pathogenesis. New York: Springer-Verlag, pp 231-238, 1984.
2. Coutelier JP, van der Logt JTM, Heessen FWA, Vink A, Van Snick J. Virally induced modulation of murine 1gG antibody subclasses. J Exp Med 168:2373-2378, 1988.
3. Stellrecht KA, Vella AT. Evidence for polyclonal B-cell activation as the mechanism for LCMV-induced autoimmune hemolytic anemia. Immunol Lett 31:273-278, 1992.
4. Coutelier JP, Johnston SJ, El Azami El Idrissi M, Pfau CJ. Involvement of CD4+ cells in lymphocytic choriomeningitis virus-induced autoimmune anaemia and hypergammaglobulinaemia. J Autoimmun 7:589-599, 1994.
5. Yang H, Dundon PL, Nahill SR, Welsh RM. Virus-induced polyclonal cytotoxic T lymphocyte stimulation. J Immunol 142:1710-1718, 1989.
6. Nahill SR, Welsh RM. High frequency of cross-reactive cytotoxic T lymphocytes elicited during the virus-induced polyclonal cytotoxic T lymphocyte response. J Exp Med 177:317-327, 1993.
7. Kasaian MT, Leite-Morris KA, Biron CA. The role of CD4+ cells in sustaining lymphocyte proliferation during lymphocytic choriomeningitis virus infection. J Immunol 146:1955-1963, 1991.
8. Gessner A, Moskophidis D, Lehmann-Grube F. Enumeration of single INF-γ-producing cells in mice during viral and bacterial infection. J Immunol 142:1293-1298, 1989.
9. Gessner A, Drjupin R, Löhler J, Lother H, Lehmann-Grube F. IFN-γ production in tissues of mice during acute infection with lymphocytic choriomeningitis virus. J Immunol 144:3160-3165, 1990.
10. Colle JH, Saron MF, Shidani B, Lembezat MP, Truffa-Bachi P. High frequency of T lymphocytes committed to interferon-γ transcription upon polyclonal activation in spleen from lymphocytic choriomeningitis virus-infected mice. Intern Immunol 5:435-441, 1993.
11. Kasaian MT, Biron CA. The activation of IL-2 transcription in L3T4+ and Lyt-2+ lymphocytes during virus infection in vivo. J Immunol 142:1287-1292, 1989.
12. Moskophidis D, Frei K, Löhler J, Fontana A, Zinkernagel RM. Production of random classes of immunoglobulins in brain tissue during persistent viral infection paralleled by secretion of interleukin-6 (IL-6) but not IL-4, IL-5, and gamma interferon. J Virol 65:1364-1369, 1991.
13. Borrow P, Oldstone MBA. Lymphocytic choriomeningitis virus. In: Nathanson N, Ed. Viral Pathogenesis. Philadelphia: Lippincott-Raven, pp 593-627, 1997.
14. Colle JH, Saron MF, Truffa-Bachi P. Altered cytokine genes expres- sion by conA-activated spleen cells from mice infected by lymphocytic choriomeningitis virus. Immunol Lett 35:247-253, 1993.
15. Butz EA, Southern PJ. Lymphocytic choriomeningitis virus-induced immune dysfunction: Induction of and recovery from T-cell anergy in acutely infected mice. J Virol 68:8477-8480, 1994.
16. Roost H, Charan S, Gebet R, Rüedi E, Hengartner H, Althage A, Zinkernagel RM. An acquired immune suppression in mice caused by infection with lymphocytic choriomeningitis virus. Eur J Immunol 18:511-518, 1988.
17. Tishon A, Borrow P, Evans C, Oldstone MBA. Virus-induced immunosuppression. I. Age at infection relates to a selective or generalized defect. Virology 195:397-405, 1993.
18. Odermatt B, Eppler M, Leist TP, Hengartner H, Zinkernagel RM. Virus-triggered acquired immunodeficiency by cytotoxic T-cell-dependent destruction of antigen-presenting cells and lymph follicle structure. Proc Natl Acad Sci USA 88:8252-8256, 1991.
19. Althage A, Odermatt B, Moskophidis D, Kündig T, Hoffman-Rohrer U, Hengartner H, Zinkernagel RM. Immunosuppression by lymphocytic choriomeningitis virus infection: Competent effector T and B cells but impaired antigen presentation. Eur J Immunol 22:1803-1812, 1992.
20. Borrow P, Evans CF, Oldstone MBA. Virus-induced immunosuppression: Immune system-mediated destruction of virus-infected dendritic cells results in generalized immune suppression. J Virol 69:1059-1070, 1995.
21. Razvi ES, Welsh RM. Programmed cell death of T lymphocytes during acute viral infection: A mechanism for virus-induced immune deficiency. J Virol 67:5754-5765, 1993.
22. Coutelier JP, Coulie PG, Wauters P, Heremans H, van der Logt JTM. In vivo polyclonal B-lymphocyte activation elicited by murine viruses. J Virol 64:5383-5388, 1990.
23. Coutelier JP, van der Logt JTM, Heessen FWA. IgG subclass distribution of primary and secondary immune responses concomitant with viral infection. J Immunol 147:1383-1386, 1991.
24. Monteyne P, Van Broeck J, Van Snick J, Coutelier JP. Inhibition by lactate dehydrogenase-elevating virus of in vivo interleukin 4 production during immunization with keyhole limpet haemocyanin. Cytokine 5:394-397, 1993.
25. Lardans V, Godfraind C, van der Logt JTM, Heessen FWA, Gonzalez MD, Coutelier JP. Polyclonal B lymphocyte activation induced by mouse hepatitis virus A59 infection. J Gen Virol 77:1005-1009, 1996.
26. Broomhall KS, Morin M, Pevear DC, Pfau CJ. Severe and transient pancytopenia associated with a chronic arenavirus infection. J Exp Pathol 3:259-269, 1987.
27. Vella AT, Pfau CJ. The presence of an anti-erythrocyte autoantibody in C3HeB/FeJ mice after lymphocytic choriomeningitis virus infection. Autoimmunity 9:319-329, 1991.
28. Jacobson S, Pfau CJ. Viral pathogenesis and resistance to defective interfering particles. Nature (London) 283:311-313, 1980.
29. Verdonck E, Pfau CJ, Gonzalez MD, Masson PL, Coutelier JP. Influence of viral infection on anti-erythrocyte autoantibody response after immunization of mice with rat red blood cells. Autoimmunity 17:73-81, 1994.
30. Dialynas DP, Wilde DB, Marrack P, Pierres A, Wall KA, Havran W, Otten G, Loken MR, Pierres M, Kappler J, Fitch FW. Characterization of the murine antigenic determinant, designated L3T4a, recognized by monoclonal antibody GK1.5: Expression of L3T4a by functional T-cell clones appears to correlate primarily with class II antigen-reactivity. Immunol Rev 74:29-56, 1983.
31. Ledbetter JA, Herzenberg LA. Xenogeneic monoclonal antibodies to mouse lymphoid differentiation antigens. Immunol Rev 47:63-90, 1979.
32. Coutelier JP, Van Snick J. Isotypically restricted activation by B lymphocytes by lactic dehydrogenase virus. Eur J Immunol 15:250-255, 1985.
33. Coutelier JP, Van Roost E, Lambotte P, Van Snick J. The murine antibody response to lactate dehydrogenase elevating virus. J Gen Virol 67:1099-1108, 1986.
34. Coutelier JP, van der Logt JTM, Heessen FWA. Rheumatoid factor production and polyclonal non-antiviral antibody responses elicited by infection with common mouse viruses. J Autoimmun 3:681-686, 1990.
35. Mazza G, Day MJ, Barker RN, Corato A, Elson CJ. Quantitation of erythrocyte bound IgG subclass autoantibodies in murine autoimmune haemolytic anaemia. Autoimmunity 23:245-255, 1996.
36. Mazza G, El Azami El Idrissi M, Coutelier JP, Corato A, Elson CJ, Pfau CJ, Day MJ. Infection of C3HeB/FeJ mice with the docile strain of lymphocytic choriomeningitis virus induces autoantibodies specific for erythrocyte band 3. Immunology 91:239-245, 1997.
37. Cox KO, Howles A. Induction and regulation of autoimmune hemolytic anemia in mice. Immunol Rev 55:31-53, 1981.
38. Naysmith JD, Ortega-Pierres MG, Elson CJ. Rat erythrocyte-induced anti-erythrocyte autoantibody production and control in normal mice. Immunol Rev 55:55-87, 1981.
39. Coutelier JP, Van Broeck J, Wolf SF. Interleukin-12 gene expression after viral infection in the mouse. J Virol 69:1955-1958, 1995.
40. Orange JS, Biron CA. An absolute and restricted requirement for IL-12 in natural killer cell IFN-γ production and antiviral defense: Studies of natural killer and T-cell responses in contrasting viral infections. J Immunol 156:1138-1142, 1996.
41. Kanangat S, Thomas J, Gangappa S, Babu JS, Rouse BT. Herpes simplex virus type 1-mediated upregulation of IL-12 (p40) mRNA expression: Implications in immunopathogenesis and protection. J Immunol 156:1110-1116, 1996.
42. Okamura H, Tsutsui H, Komatsu T, Yutsudo M, Hakura A, Tanimoto T, Torigoe K, Okura T, Nukada Y, Hattori K, Akita K, Namba M, Tanabe F, Konishi K, Fukuda S, Kurimoto M. Cloning of a new cytokine that induces IFN-γ production by T cells. Nature (London) 378:88-91, 1995.
43. Stellrecht-Broomhall KA. Evidence for immune-mediated destruction as mechanism for LCMV-induced anemia in persistently infected mice. Viral Immunol 4:269-280, 1991.
44. Shen CR, Mazza G, Perry FE, Beech JT, Thompson SJ, Corato A, Newton S, Barker RN, Elson CJ. T-helper 1 dominated responses to erythrocyte band 3 in NZB mice. Immunology 89:195-199, 1996.
45. Christensen JP, Röpke C, Thomsen AR. Virus-induced polyclonal T-cell activation is followed by apoptosis: Partitioning of CD8+ T cells based on α4 integrin expression. Intern Immunol 8:707-715, 1996.
46. Tough DF, Borrow P, Sprent J. Induction of bystander T-cell proliferation by viruses and type I interferon in vivo. Science 272:1947-1950, 1996.