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Volumn 26, Issue 4, 1998, Pages 562-569

TGFα is dispensable for skin tumorigenesis in Tg.AC mice

Author keywords

Epidermal growth factor receptor (EGFR); Oncogene; TPA; Transgenic mice; v Ha ras; Wounding

Indexed keywords

EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; PHORBOL 13 ACETATE 12 MYRISTATE; TRANSFORMING GROWTH FACTOR ALPHA;

EID: 0031824594     PISSN: 01926233     EISSN: None     Source Type: Journal    
DOI: 10.1177/019262339802600413     Document Type: Article
Times cited : (8)

References (44)
  • 1
    • 0027169767 scopus 로고
    • A reagent for the single-step simultaneous isolation of RNA, DNA and proteins from cell and tissue samples
    • Chomczynski P (1993). A reagent for the single-step simultaneous isolation of RNA, DNA and proteins from cell and tissue samples. BioTechniques 15: 532-537.
    • (1993) BioTechniques , vol.15 , pp. 532-537
    • Chomczynski, P.1
  • 2
    • 0023277545 scopus 로고
    • Single step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • Chomczynski P and Sacchi N (1987). Single step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162: 156-159.
    • (1987) Anal. Biochem. , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 4
    • 0000336139 scopus 로고
    • Regression models and life-tables
    • Cox DR (1972). Regression models and life-tables. J. R. Stat. Soc. B34: 187-220.
    • (1972) J. R. Stat. Soc. , vol.B34 , pp. 187-220
    • Cox, D.R.1
  • 5
    • 0023037089 scopus 로고
    • Transforming growth factor-α: Structure and biological activities
    • Derynck R (1986). Transforming growth factor-α: Structure and biological activities. J. Cell. Biochem. 32: 293-304.
    • (1986) J. Cell. Biochem. , vol.32 , pp. 293-304
    • Derynck, R.1
  • 6
    • 0023807364 scopus 로고
    • Transforming growth factor α
    • Derynck R (1988). Transforming growth factor α. Cell 54: 593-595.
    • (1988) Cell , vol.54 , pp. 593-595
    • Derynck, R.1
  • 7
    • 0023100052 scopus 로고
    • Synthesis of messenger RNAs for transforming growth factors a and β and the epidermal growth factor receptor by human tumors
    • Derynck R, Goeddel DV, Ullrich A, Gutterman JU, Williams RD, Bringman TS, and Berger WH (1987). Synthesis of messenger RNAs for transforming growth factors a and β and the epidermal growth factor receptor by human tumors. Cancer Res. 47: 707-712.
    • (1987) Cancer Res. , vol.47 , pp. 707-712
    • Derynck, R.1    Goeddel, D.V.2    Ullrich, A.3    Gutterman, J.U.4    Williams, R.D.5    Bringman, T.S.6    Berger, W.H.7
  • 8
    • 0021752924 scopus 로고
    • Human transforming growth factor-α: Precursor structure and expression in E. coli
    • Derynck R, Roberts AB, Winkler ME, Chen EY, and Goeddel DV (1984). Human transforming growth factor-α: Precursor structure and expression in E. coli. Cell 38: 287-297.
    • (1984) Cell , vol.38 , pp. 287-297
    • Derynck, R.1    Roberts, A.B.2    Winkler, M.E.3    Chen, E.Y.4    Goeddel, D.V.5
  • 9
    • 0026729695 scopus 로고
    • Multistage carcinogenesis in mouse skin
    • DiGiovanni J (1992). Multistage carcinogenesis in mouse skin. Pharmacol. Ther. 54: 63-128.
    • (1992) Pharmacol. Ther. , vol.54 , pp. 63-128
    • DiGiovanni, J.1
  • 13
    • 0024334332 scopus 로고
    • Stimulatory role of transforming growth factors in multistage skin carcinogenesis: Possible explanation for the tumor-inducing effect of wounding in initiated NMRI mouse skin
    • Furstenberger G, Rogers M, Schnapke R, Bauer G, Hofler P, and Marks F (1989). Stimulatory role of transforming growth factors in multistage skin carcinogenesis: Possible explanation for the tumor-inducing effect of wounding in initiated NMRI mouse skin. Int. J. Cancer 43: 915-921.
    • (1989) Int. J. Cancer , vol.43 , pp. 915-921
    • Furstenberger, G.1    Rogers, M.2    Schnapke, R.3    Bauer, G.4    Hofler, P.5    Marks, F.6
  • 14
    • 0028285527 scopus 로고
    • Focal transgene expression associated with papilloma development in v-Ha-ras-transgenic Tg.AC mice
    • Hansen LA and Tennant RW (1994). Focal transgene expression associated with papilloma development in v-Ha-ras-transgenic Tg.AC mice. Mol. Carcinog. 9: 143-156.
    • (1994) Mol. Carcinog. , vol.9 , pp. 143-156
    • Hansen, L.A.1    Tennant, R.W.2
  • 15
    • 0025904265 scopus 로고
    • A heparin-binding growth factor secreted by macrophage-like cells that is related to EGF
    • Higashiyama S, Abraham JA, Miller J, Fiddes JC, and Klagsburn M (1991). A heparin-binding growth factor secreted by macrophage-like cells that is related to EGF. Science 251: 936-939.
    • (1991) Science , vol.251 , pp. 936-939
    • Higashiyama, S.1    Abraham, J.A.2    Miller, J.3    Fiddes, J.C.4    Klagsburn, M.5
  • 16
    • 0025802893 scopus 로고
    • Evidence for autocrine/paracrine growth stimulation by transforming growth factor-α during the process of skin tumor promotion
    • Imamoto A, Beltran LM, and DiGiovanni J (1991). Evidence for autocrine/paracrine growth stimulation by transforming growth factor-α during the process of skin tumor promotion. Mol. Carcinog. 4: 52-60.
    • (1991) Mol. Carcinog. , vol.4 , pp. 52-60
    • Imamoto, A.1    Beltran, L.M.2    DiGiovanni, J.3
  • 17
    • 0025341727 scopus 로고
    • TGFa overexpression in transgenic mice induces liver neoplasia and abnormal development of the mammary gland and pancreas
    • Jhappan C, Stahle C, Harkins RH, Fausto N, Smith GH, and Merlino GT (1990). TGFa overexpression in transgenic mice induces liver neoplasia and abnormal development of the mammary gland and pancreas. Cell 61: 1137-1146.
    • (1990) Cell , vol.61 , pp. 1137-1146
    • Jhappan, C.1    Stahle, C.2    Harkins, R.H.3    Fausto, N.4    Smith, G.H.5    Merlino, G.T.6
  • 18
    • 0027931473 scopus 로고
    • Transgenic mice provide genetic evidence that transforming growth factor alpha promotes skin tumorigenesis via H-ras-dependent and H-ras-independent pathways
    • Jhappan C, Takayama H, Dickerson RB, and Merlino G (1994). Transgenic mice provide genetic evidence that transforming growth factor alpha promotes skin tumorigenesis via H-ras-dependent and H-ras-independent pathways. Cell. Growth Differ. 5: 385-394.
    • (1994) Cell. Growth Differ. , vol.5 , pp. 385-394
    • Jhappan, C.1    Takayama, H.2    Dickerson, R.B.3    Merlino, G.4
  • 19
    • 0000941980 scopus 로고
    • A distribution-free k-sample test against ordered alternatives
    • Jonckheere AR (1954). A distribution-free k-sample test against ordered alternatives. Biometrika 41: 133-145.
    • (1954) Biometrika , vol.41 , pp. 133-145
    • Jonckheere, A.R.1
  • 20
    • 0030893214 scopus 로고    scopus 로고
    • Analysis of the ability of 12-O-tetradecanoylphorbol-13-acetate to induce epidermal hyperplasia, transforming growth factor-α, and skin tumor promotion in wa-1 mice
    • Kiguchi K, Beltran L, Dubowski A, and DiGiovanni J (1997). Analysis of the ability of 12-O-tetradecanoylphorbol-13-acetate to induce epidermal hyperplasia, transforming growth factor-α, and skin tumor promotion in wa-1 mice. J. Invest. Dermatol. 108: 784-791.
    • (1997) J. Invest. Dermatol. , vol.108 , pp. 784-791
    • Kiguchi, K.1    Beltran, L.2    Dubowski, A.3    DiGiovanni, J.4
  • 21
    • 0028922715 scopus 로고
    • Elevation of transforming growth factor-α mRNA and protein expression by diverse tumor promoters in SENCAR mouse epidermis
    • Kiguchi K, Beltran L, You J, Rho O, and DiGiovanni J (1995). Elevation of transforming growth factor-α mRNA and protein expression by diverse tumor promoters in SENCAR mouse epidermis. Mol. Carcinog. 12: 225-235.
    • (1995) Mol. Carcinog. , vol.12 , pp. 225-235
    • Kiguchi, K.1    Beltran, L.2    You, J.3    Rho, O.4    DiGiovanni, J.5
  • 22
    • 0025647881 scopus 로고
    • v-Ha-ras transgene abrogates the initiation step in mouse skin tumorigenesis: Effects of phorbol esters and retinoic acid
    • Leder A, Kuo A, Cardiff RD, Sinn E, and Leder P (1990). v-Ha-ras transgene abrogates the initiation step in mouse skin tumorigenesis: Effects of phorbol esters and retinoic acid. Proc. Natl. Acad. Sci. USA 87: 9178-9182.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 9178-9182
    • Leder, A.1    Kuo, A.2    Cardiff, R.D.3    Sinn, E.4    Leder, P.5
  • 23
    • 0027297643 scopus 로고
    • TGFa deficiency results in hair follicle and eye abnormalities in targeted and Waved-1 mice
    • Luetteke NC, Qiu TH, Peiffer RL, Oliver P, Smithies O, and Lee DC (1993). TGFa deficiency results in hair follicle and eye abnormalities in targeted and Waved-1 mice. Cell 73: 263-278.
    • (1993) Cell , vol.73 , pp. 263-278
    • Luetteke, N.C.1    Qiu, T.H.2    Peiffer, R.L.3    Oliver, P.4    Smithies, O.5    Lee, D.C.6
  • 24
    • 0027315183 scopus 로고
    • Mice with a null mutation of the TGFα gene have abnormal skin architecture, wavy hair, and curly whiskers and often develop corneal inflammation
    • Mann GB, Fowler KJ, Gabriel A, Nice EC, Williams RL, and Dunn AR (1993). Mice with a null mutation of the TGFα gene have abnormal skin architecture, wavy hair, and curly whiskers and often develop corneal inflammation. Cell 73: 249-261.
    • (1993) Cell , vol.73 , pp. 249-261
    • Mann, G.B.1    Fowler, K.J.2    Gabriel, A.3    Nice, E.C.4    Williams, R.L.5    Dunn, A.R.6
  • 26
    • 0021360015 scopus 로고
    • Rat transforming growth factor type 1 structure and relation to epidermal growth factor
    • Marquardt H, Hunkapiller MW, Hood LE, and Todaro GJ (1984). Rat transforming growth factor type 1 structure and relation to epidermal growth factor. Science 223: 1079-1082.
    • (1984) Science , vol.223 , pp. 1079-1082
    • Marquardt, H.1    Hunkapiller, M.W.2    Hood, L.E.3    Todaro, G.J.4
  • 27
    • 0021013896 scopus 로고
    • Epidermal growth factor-like transforming growth factor
    • Massague' J (1983). Epidermal growth factor-like transforming growth factor. J. Biol. Chem. 258: 13614-13620.
    • (1983) J. Biol. Chem. , vol.258 , pp. 13614-13620
    • Massague', J.1
  • 28
    • 0025647695 scopus 로고
    • Transforming growth factor-α: A model for membrane-anchored growth factors
    • Massague' J (1990). Transforming growth factor-α: A model for membrane-anchored growth factors. J. Biol. Chem. 265: 21303-21396.
    • (1990) J. Biol. Chem. , vol.265 , pp. 21303-21396
    • Massague', J.1
  • 29
    • 0025372023 scopus 로고
    • Development of mammary hyperplasia and neoplasia in MMTV-TGFα transgenic mice
    • Matsui Y, Halter SA, Holt JT, Hogan BLM, and Coffey RJ (1990). Development of mammary hyperplasia and neoplasia in MMTV-TGFα transgenic mice. Cell 61: 1147-1155.
    • (1990) Cell , vol.61 , pp. 1147-1155
    • Matsui, Y.1    Halter, S.A.2    Holt, J.T.3    Hogan, B.L.M.4    Coffey, R.J.5
  • 30
    • 0028034699 scopus 로고
    • Altered expression of the epidermal growth factor receptor and transforming growth factor-aα during multistage skin carcinogenesis in SENCAR mice
    • Rho O, Beltran LM, Gimenez-Conti IB, and DiGiovanni D (1994). Altered expression of the epidermal growth factor receptor and transforming growth factor-aα during multistage skin carcinogenesis in SENCAR mice. Mol. Carcinog. 11: 19-28.
    • (1994) Mol. Carcinog. , vol.11 , pp. 19-28
    • Rho, O.1    Beltran, L.M.2    Gimenez-Conti, I.B.3    DiGiovanni, D.4
  • 31
    • 0025634139 scopus 로고
    • Transforming growth factor α: An oncodevelopmental growth factor
    • Salomon DS, Kim N, Saeki T, and Ciardiello F (1990). Transforming growth factor α: An oncodevelopmental growth factor. Cancer Cells 2: 389-397.
    • (1990) Cancer Cells , vol.2 , pp. 389-397
    • Salomon, D.S.1    Kim, N.2    Saeki, T.3    Ciardiello, F.4
  • 32
    • 0025297086 scopus 로고
    • Overexpression of TGFα in transgenic mice: Induction of epithelial hyperplasia, pancreatic metaplasia, and carcinoma of the breast
    • Sandgren EP, Luetteke NC, Palmiter RD, Brinster RL, and Lee DC (1990). Overexpression of TGFα in transgenic mice: Induction of epithelial hyperplasia, pancreatic metaplasia, and carcinoma of the breast. Cell 61: 1121-1135.
    • (1990) Cell , vol.61 , pp. 1121-1135
    • Sandgren, E.P.1    Luetteke, N.C.2    Palmiter, R.D.3    Brinster, R.L.4    Lee, D.C.5
  • 33
    • 0027454943 scopus 로고
    • Transforming growth factor alpha dramatically enhances oncogene-induced carcinogenesis in transgenic mouse pancreas and liver
    • Sandgren EP, Luetteke NC, Qiu TH, Palmiter RD, Brinster RL, and Lee DC (1993). Transforming growth factor alpha dramatically enhances oncogene-induced carcinogenesis in transgenic mouse pancreas and liver. Mol. Cell Biol. 13: 320-330.
    • (1993) Mol. Cell Biol. , vol.13 , pp. 320-330
    • Sandgren, E.P.1    Luetteke, N.C.2    Qiu, T.H.3    Palmiter, R.D.4    Brinster, R.L.5    Lee, D.C.6
  • 35
    • 0024593476 scopus 로고
    • Structure and function of human amphiregulin: A member of the epidermal growth factor family
    • Shoyab M, Plowman GD, McDonald VL, Bradley JG, and Todaro GJ (1989). Structure and function of human amphiregulin: A member of the epidermal growth factor family. Science 243: 1074-1076.
    • (1989) Science , vol.243 , pp. 1074-1076
    • Shoyab, M.1    Plowman, G.D.2    McDonald, V.L.3    Bradley, J.G.4    Todaro, G.J.5
  • 37
    • 0027237453 scopus 로고
    • Chemically induced skin carcinogenesis in a transgenic mouse line (Tg.AC) carrying a v-Ha-ras gene
    • Spalding JW, Momma J, Elwell MR, and Tennant RW (1993). Chemically induced skin carcinogenesis in a transgenic mouse line (Tg.AC) carrying a v-Ha-ras gene. Carcinogenesis 14: 1335-1341.
    • (1993) Carcinogenesis , vol.14 , pp. 1335-1341
    • Spalding, J.W.1    Momma, J.2    Elwell, M.R.3    Tennant, R.W.4
  • 38
    • 0016759979 scopus 로고
    • Tests for trend in life table analysis
    • Tarone RE (1975). Tests for trend in life table analysis. Biometrika 62: 679-682.
    • (1975) Biometrika , vol.62 , pp. 679-682
    • Tarone, R.E.1
  • 39
    • 0017097271 scopus 로고
    • Transformation by murine and feline sarcoma viruses specifically blocks binding of epidermal growth factor to cells
    • Todaro GJ, De Larco JE, and Cohen S (1976). Transformation by murine and feline sarcoma viruses specifically blocks binding of epidermal growth factor to cells. Nature 264: 26-31.
    • (1976) Nature , vol.264 , pp. 26-31
    • Todaro, G.J.1    De Larco, J.E.2    Cohen, S.3
  • 40
    • 0013543749 scopus 로고
    • Transforming growth factors produced by certain tumor cells: Polypeptides that interact with epidermal growth factor receptors
    • Todaro GJ, Fryling C, and De Larco JE (1980). Transforming growth factors produced by certain tumor cells: Polypeptides that interact with epidermal growth factor receptors. Proc. Natl. Acad. Sci. USA 77: 5258-5262.
    • (1980) Proc. Natl. Acad. Sci. USA , vol.77 , pp. 5258-5262
    • Todaro, G.J.1    Fryling, C.2    De Larco, J.E.3
  • 41
    • 0025876488 scopus 로고
    • Transgenic mice provide new insights into the role of TGF-α during epidermal development and differentiation
    • Vassar R and Fuchs E (1991). Transgenic mice provide new insights into the role of TGF-α during epidermal development and differentiation. Genes Dev. 5: 714-727.
    • (1991) Genes Dev. , vol.5 , pp. 714-727
    • Vassar, R.1    Fuchs, E.2
  • 42
    • 0026485388 scopus 로고
    • Tissue distribution of mRNA for heparin-binding epidermal growth factor
    • Vaughn TJ, Paschall JC, and Brown KD (1992). Tissue distribution of mRNA for heparin-binding epidermal growth factor. Biochem. J. 287: 681-684.
    • (1992) Biochem. J. , vol.287 , pp. 681-684
    • Vaughn, T.J.1    Paschall, J.C.2    Brown, K.D.3
  • 44
    • 0024504360 scopus 로고
    • The TGF-α precursor expressed on the cell surface binds to the EGF receptor on adjacent cells, leading to signal transduction
    • Wong ST, Winchell LF, McCune BK, Earp HS, Teixido' J, Massague' J, Herman B, and Lee DC (1989). The TGF-α precursor expressed on the cell surface binds to the EGF receptor on adjacent cells, leading to signal transduction. Cell 56: 495-506.
    • (1989) Cell , vol.56 , pp. 495-506
    • Wong, S.T.1    Winchell, L.F.2    McCune, B.K.3    Earp, H.S.4    Teixido', J.5    Massague', J.6    Herman, B.7    Lee, D.C.8


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