In vitro characterization of a novel series of platelet-derived growth factor receptor tyrosine kinase inhibitors

Biochemical Pharmacology

Volumn 51, Issue 12, 1996, Pages 1631-1638

  Sawutz, David G ^a,b   Bode, Donald C ^a   Briggs, G Maurice ^a   Reid, John R ^a   Canniff, Paul ^a   Caldwell, Lisa ^a   Faltynek, Connie R ^a   Miller, Deborah ^a   Dunn, Joseph A ^a   De Garavilla, Lawrence ^a   Guiles, Joseph W ^a   Weigelt, Carolyn ^a   Michne, William ^a   Treasurywala, Adi M ^a   Silver, Paul J ^a  

^a Sterling Winthrop Pharmaceut R ^*  (United States)

^b AMGEN INC   (United States)

Author keywords

platelet derived growth factor; platelet derived growth factor receptor; platelet derived growth factor receptor tyrosine kinase inhibitors; tyrosine kinase; vascular smooth muscle cells

Indexed keywords

ADENOSINE TRIPHOSPHATE; BIARYLHYDRAZONE DERIVATIVE; ISOENZYME; NEW DRUG; PLATELET DERIVED GROWTH FACTOR BB; PLATELET DERIVED GROWTH FACTOR RECEPTOR; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE KINASE INHIBITOR; RECOMBINANT PLATELET DERIVED GROWTH FACTOR BB; UNCLASSIFIED DRUG; WIN 41662; WIN 45838; WIN 72039;

ARTICLE; AUTOPHOSPHORYLATION; CALCIUM MOBILIZATION; CELL CULTURE; CELL PROLIFERATION; COMPETITIVE INHIBITION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DRUG INHIBITION; DRUG SPECIFICITY; HUMAN; HUMAN CELL; MALE; PRIORITY JOURNAL; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE;

EID: 0030007675     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-2952(96)00112-8     Document Type: Article

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