Adjuvant action of Chenopodium quinoa saponins on the induction of antibody responses to intragastric and intranasal administered antigens in mice

Comparative Immunology, Microbiology and Infectious Diseases

Volumn 21, Issue 3, 1998, Pages 225-236

  Estrada, Alberto ^a   Li, Bing ^a   Laarveld, Bernard ^a  

^a UNIVERSITY OF SASKATCHEWAN   (Canada)

Author keywords

Adjuvant; Antibody responses; Intestinal permeability; Mucosal immunity; Quinoa saponins

Indexed keywords

CHOLERA TOXIN; IMMUNOGLOBULIN A; IMMUNOGLOBULIN A ANTIBODY; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G ANTIBODY; IMMUNOLOGICAL ADJUVANT; OVALBUMIN; PLANT EXTRACT; SAPONIN; VACCINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY RESPONSE; ARTICLE; BRONCHUS SECRETION; DRUG ADMINISTRATION; DRUG DELIVERY SYSTEM; FEMALE; IMMUNOPOTENTIATION; INTRANASAL DRUG ADMINISTRATION; ISOTOPE LABELING; MOUSE; MUCOSAL IMMUNITY; NONHUMAN; PLANT SEED;

ADJUVANTS, IMMUNOLOGIC; ADMINISTRATION, INTRANASAL; ADMINISTRATION, ORAL; ANIMALS; ANTIBODY FORMATION; CEREALS; CHENOPODIACEAE; CHOLERA TOXIN; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HEMOLYSIS; IMMUNITY, MUCOSAL; IMMUNOGLOBULIN A, SECRETORY; IMMUNOGLOBULIN G; INTESTINAL MUCOSA; LUNG; MICE; MICE, INBRED BALB C; OVALBUMIN; PERMEABILITY; SAPONINS; SEEDS; SHEEP;

ANIMALIA; BRONCHUS; CHENOPODIUM QUINOA;

EID: 0031819540     PISSN: 01479571     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0147-9571(97)00030-1     Document Type: Article

References (24)

1. Michalek SM, Morisaki I, Gregory RL, Kiyono H, Hamada S, McGhee JR. Oral adjuvants enhance IgA responses to Streptococcus mutans. Mol. Immunol. 1983;20:1009-18.
2. Keren DF, McDonald RA, Carey JL. Combined parenteral and oral immunization results in an enhanced mucosal immunoglobulin. A response to Shigella flexneri. Infect. Immun. 1988;56:910-5.
3. Bergmann KC, Waldman RH. Enhanced murine respiratory tract IgA antibody response to oral influenza vaccine when combined with a lipoidal amine (avridine). Int. Arch. Allergy Appl. Immunol. 1988;87:334-5.
4. Elson CO and Dertzbaugh MT, Mucosal adjuvants. In Handbook of Mucosal Immunology, Edited by Ogra P, Mestecky J, Lamm M, Strober W, McGhee J and Bienenstock J, pp. 391-402. Academic Press Inc., San Diego, CA (1994).
5. Price KR, Johnson IT, Fenwick GR. The chemistry and biological significance of saponins in foods and feedingstuffs. CRC Crit. Rev. Food Sci. Nutr. 1987;26:27-135.
6. Campbell JB, Peerbaye YA. Saponin. Res. Immunol. 1992;143:526-30.
7. Kensil CR, Patel U, Lennick M, Marciani D. Separation and characterization of saponins with adjuvant activity from Quillaja saponaria Molina cortex. J. Immunol. 1991;146:431-7.
8. Kenarova B, Neychev H, Hadjiivanova C, Petkov V. Immunomodulating activity of ginsenoside Rg1 from Panax ginseng. Japan J. Pharmacol. 1990;54:447-54.
9. Phillips JC, Butterworth KR, Gaunt IF, Evans JG and Grasso P, Long-term toxicity study of Quillaja extract in mice, Vol. 17, Edited by Cosmet. Toxicol., pp. 23-27 (1979).
10. Maharaj I, Froh KJ, Campbell JB. Immune responses of mice to inactivated rabies vaccine administered orally: potentiation by Quillaja saponins. Can. J. Microbiol. 1986;32:414-20.
11. Chavali SR, Campbell JB. Adjuvant effects of orally administered saponins on humoral and cellular immune responses in mice. Immunobiol. 1987;174:347-59.
12. Chavali SR, Campbell JB. Immunomodulatory effects of orally-administered saponins and nonspecific resistance against rabies infection. Int. Archs. Allergy appl. Immun. 1987;84:129-34.
13. Chavali SR, Barton LD, Campbell JB. Immunopotentiation by orally-administered Quillaja saponins: effects in mice vaccinated intraperitoneally against rabies. Clin. Exp. Immunol. 1988;74:339-43.
14. Risi JC, Galwey NW. The Chenopodium grains of the Andes: Inca crops for modern agriculture. Adv. Appl. Biol. 1984;10:145-216.
15. Galwey NW, Leakey CL, Price KR, Fenwick GR. Chemical composition and nutritional characteristics of quinoa (Chenopodium quinoa). Human Nutr. Food Sci. Nutr. 1990;42:245-61.
16. Ridout CL, Price KR, DuPont SM, Parker ML, Fenwick RG. Quinoa saponins - analysis and preliminary investigations into the effects of reduction by processing. J. Sci. Food Agric. 1991;54:165-76.
17. Heinstein PF, McLaughlin JL. Additional toxic, bitter saponins from the seeds of Chenopodium quinoa. J. Nat. Prod. 1989;52:1132-5.
18. Mizui F, Kasai R, Ohtani K, Tanaka O. Saponins from brans of quinoa, Chenopodium quinoa. Willd. Chem. Pharm. Bull. 1988;36:1415-8.
19. Kramer DR, Sutherland RM, Bao S, Husband AJ. Cytokine mediated effects in mucosal immunity. Immunol. Cell Biol. 1995;73:389-96.
20. Aizpurua HJ, Russell-Jones GJ. Oral vaccination. Identification of classes of proteins that provoke an immune response upon oral feeding. J. Exp. Med. 1988;167:440-51.
21. Lovgren K, Kaberg H, Morein B. An experimental influenza subunit vaccine (iscom): Induction of protective immunity to challenge infection in mice after intranasal or subcutaneous administration. Clin. Exp. Immunol. 1990;82:435-9.
22. Domon B, Hostettmann K. New saponins from Phytolacca dodecandra. Helv. Chim. Acta 1984;67:1310-5.
23. Onning G, Wang Q, Westrom BR, Asp NG, Karlsson BW. Influence of oat saponins on intestinal permeability in vitro and in vivo in the rat. Brit. J. Nutr. 1996;76:141-51.
24. Johnson IT, Gee JM, Price K, Curl C, Fenwick GR. Influence of saponins on gut permeability and active nutrient transport in vitro. J. Nutr. 1986;116:2270-7.