Studies on 2-benzyloxy-4H-3,1-benzoxazin-4-ones as serine protease inhibitors

Pharmaceutica Acta Helvetiae

Volumn 73, Issue 2, 1998, Pages 95-103

  Gütschow, Michael ^a   Neumann, Ulf ^b   Sieler, Joachim ^a   Eger, Kurt ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

^b NOVARTIS PHARMA AG   (Switzerland)

Author keywords

4H 3,1 benzoxazin 4 ones; Crystal structure analysis; Enzyme inhibition; Serine proteascs

Indexed keywords

4H 3,1 BENZOXAZIN 4 ONE DERIVATIVE; SERINE PROTEINASE INHIBITOR;

ARTICLE; CRYSTAL STRUCTURE; DRUG HYDROLYSIS; DRUG SYNTHESIS; ENZYME INHIBITION; HUMAN; IN VITRO STUDY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; STRUCTURE ACTIVITY RELATION; X RAY CRYSTALLOGRAPHY;

CRYSTALLOGRAPHY, X-RAY; HUMANS; HYDROLYSIS; KINETICS; LEUKOCYTE ELASTASE; LEUKOCYTES; OXAZINES; SERINE PROTEINASE INHIBITORS;

EID: 0031818465     PISSN: 00316865     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0031-6865(98)00003-X     Document Type: Article

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