Over-expression of glutathione S-transferase Yp isozyme and concomitant down-regulation of Ya isozyme in renal cell carcinoma of rats induced by ferric nitrilotriacetate

Carcinogenesis

Volumn 19, Issue 5, 1998, Pages 897-903

  Tanaka, Tomoyuki ^a   Nishiyama, Yasuyuki ^a   Okada, Kunihiko ^a,b   Satoh, Kimihiko ^c   Fukuda, Aya ^b   Uchida, Koji ^b   Osawa, Toshihiko ^b   Hiai, Hiroshi ^a   Toyokuni, Shinya ^a  

^a KYOTO UNIVERSITY   (Japan)

^b NAGOYA UNIVERSITY   (Japan)

^c HIROSAKI UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTATHIONE TRANSFERASE; ISOENZYME; MESSENGER RNA; NITRILOTRIACETATE IRON;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER MODEL; CARCINOGENESIS; CONTROLLED STUDY; DETOXIFICATION; ENZYME ACTIVITY; IMMUNOHISTOCHEMISTRY; KIDNEY CARCINOMA; MALE; METASTASIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

ANIMALS; BLOTTING, WESTERN; CARCINOGENS; CARCINOMA, RENAL CELL; DOWN-REGULATION; FERRIC COMPOUNDS; GLUTATHIONE TRANSFERASE; IMMUNOHISTOCHEMISTRY; ISOENZYMES; KIDNEY NEOPLASMS; MALE; NITRILOTRIACETIC ACID; RATS; RATS, WISTAR;

EID: 0031815385     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/19.5.897     Document Type: Article

References (42)

1. Anderson,R.L., Bishop,W.E. and Campbell,R.L. (1985) A review of the environmental and mammalian toxicology of nitrilotriacetic acid. Crit. Rev. Toxicol., 15, 1-102.
2. Okada,S. and Midorikawa,O. (1982) Induction of rat renal adenocarcinoma by Fe-nitrilotriacetate (Fe-NTA). Jpn. Arch. Intern. Med., 29, 485-491.
3. Ebina,Y., Okada,S., Hamazaki,S., Ogino,F., Li,J.-L. and Midorikawa,O. (1986) Nephrotoxicity and renal cell carcinoma after use of iron- and aluminum-nitrilotriacetate complexes in rats. J. Natl Cancer Inst., 76, 107-113.
4. Li,J.-L., Okada,S., Hamazaki,S., Ebina,Y. and Midorikawa,O. (1987) Subacute nephrotoxicity and induction of renal cell carcinoma in mice treated with ferric nitrilotriacetate. Cancer Res., 47, 1867-1869.
5. Okada,S. (1996) Iron-induced tissue damage and cancer: the role of reactive oxygen free radicals. Pathol. Int., 46, 311-332.
6. Toyokuni,S. (1996) Iron-induced carcinogenesis: the role of redox regulation. Free Radic. Biol. Med., 20, 553-566.
7. Toyokuni,S., Mori,T. and Dizdaroglu,M. (1994) DNA base modifications in renal chromatin of Wistar rats treated with a renal carcinogen, ferric nitrilotriacetate. Int. J. Cancer, 57, 123-128.
8. Toyokuni,S., Mori,T., Hiai,H. and Dizdaroglu,M. (1995) Treatment of Wistar rats with a renal carcinogen, ferric nitrilotriacetate, causes DNA-protein cross-linking between thymine and tyrosine in their renal chromatin. Int. J. Cancer, 62, 309-313.
9. Toyokuni,S., Okada,S., Hamazaki,S., Minamiyama,Y., Yamada,Y., Liang,P., Fukunaga,Y. and Midorikawa,O. (1990) Combined histochemical and biochemical analysis of sex hormone dependence of ferric nitrilotriacetate-induced renal lipid peroxidation in ddY mice. Cancer Res., 50, 5574-5580.
10. Toyokuni,S., Uchida,K., Okamoto,K., Hattori-Nakakuki,Y., Hiai,H. and Studtman,E.R. (1994) Formation of 4-hydroxy-2-nonenal-modified proteins in the renal proximal tubules of rats treated with a renal carcinogen, ferric nitrilolriacetate. Proc. Natl Acad. Sci. USA, 91, 2616-2620.
11. 7_12 acyloins in the kidney of Wistar rats after treatment with a renal carcinogen, ferric nitrilotriacetale. Free Radic. Biol. Med., 22, 1019-1027.
12. Uchida,K., Fukuda,A., Kawakishi,S., Hiai,H. and Toyokuni,S. (1995) A renal carcinogen ferric nitrilotriacetate mediates a temporary accumulation of aldehyde-modified proteins within cytosolic compartment of rat kidney. Arch. Biochem. Biophys., 317, 405-411.
13. Chasseau,L.F. (1979) The role of glutathione and glutathione S-transferase in the metabolism of chemical carcinogens and other electrophilic agents. Cancer Res., 29, 175-274.
14. Mannervik,K.B. (1985) The isozymes of glutathione transferase. Adv. Enzymol. Relat. Areas Mol. Biol., 57, 357-417.
15. Soma,Y., Satoh,K. and Sato,K. (1986) Purification and subunit structural and immunological characterization of five glutathione S-transferase in human liver and the acidic form as a hepatic tumour marker. Biochem. Biophys. Acta, 869, 247-258.
16. Hayes,J.D. and Mantle,T.J. (1986) Use of immuno-blot techniques to discriminate between the glutathione S-transferase Yf, Yk, Ya, Yn/Yb, and Yc subunits and to study their distribution in extrahepatic tissues. Biochem. J., 233, 779-788.
17. Fukuda,A., Osawa,T., Oda,H., Toyokuni,S., Satoh,K. and Uchida,K. (1996) Oxidative stress response in iron-induced renal carcinogenesis: acute nephrotoxicity mediates the enhanced expression of glutathione S-transferase Yp isozyme. Arch. Biochem. Biophys., 329, 39-46.
18. Habig,W.H., Pabst,M.J. and Jakoby,W.B. (1974) Glutathione S-transferases. The first enzymatic step in mercapturic acid formation. J Biol. Chem., 249, 7130-7139.
19. Satoh,K., Kitahara,A., Soma,Y., Inaba,Y., Hatayama,I. and Sato,K. (1985) Purification, induction, and distribution of placental glutathione transferase: a new marker enzyme for preneoplastic cells in the rat chemical hepatocarcinogenesis. Proc. Natl Acad. Sci. USA, 82, 3964-3968.
20. Hsu,S.-M., Raine,N. and Fanger,H. (1981) A comparative study of the peroxidase-antiperoxidase method and avidin-biotin complex method for studying polypeptide hormones with radioimmunoassay antibodies. Am. J. Clin. Pathol., 75, 734-738.
21. Suguoka,Y., Kano,T., Okuda,A., Sakai,M., Kitagawa,T. and Muramatsu,M. (1985) Cloning and the nucleotide sequence of rat glutathione S-transferase P cDNA. Nucleic Acids Res., 13, 6049-6057.
22. Pickett,C.B., Telakowski Hopkins,C.A., Ding,G.J., Argenbright,L. and Lu,A.Y. (1984) Rat liver glutathione S-transferases. Complete nucleotide sequence of a glutathione S-transferase mRNA and the regulation of the Ya, Yb, and Yc mRNAs by 3-methylcholanthrene and phenobarbital. J Biol. Chem., 259, 5182-5188.
23. Sambrook,J., Fritsch,E.F. and Maniatis,T. (1989) Molecular Cloning: A Laboratory Manual. Cold Spring Harbor Laboratory. Cold Spring Harbor, NY
24. Japanese Urological Association, the Japanese Society of Pathology, and Japan Radiological Society (1992) General Rule for Clinical and Pathological Studies on Renal Cell Carcinoma. Kanehara Publication Co. Ltd., Tokyo.
25. Toyokuni,S., Tanaka,T. Nishiyama,Y., Okamoto,K., Nakashima,Y., Hamazaki,S., Okada,S. and Hiai,H. (1996) Induction of renal cell carcinoma in male Wistar rats treated with cupric nitrilotriacetate. Lab. Invest., 75, 239-248.
26. Oberley,T.D., Friedman,A.L., Moser,R. and Siegel,F.L. (1995) Effects of lead administration on developing rat kidney. II. Functional, morphologic, and immunohistochemical studies. Toxicol. Appl. Pharmacol., 131, 94-107.
27. Moser,R., Oberley,T.D., Daggett,D.A., Friedman,A.L., Johnson,J.A. and Siegel,F.L. (1995) Effects of lead administration on developing rat kidney. I. Glutathione S-transferase isoenzymes. Toxicol. Appl. Pharmacol., 131, 85-93.
28. Klone,A., Weidner,U., Hussnaetter,R., Harris,J., Meyer,D., Peter,S., Ketterer,B. and Sies,H. (1990) Decreased expression of the glutathione S-transferases alfa and pi genes in human renal cell carcinoma. Carcinogenesis, 11, 2179-2183.
29. Di Ilio,C., Aceto,A., Bucciarelli,T., Angelucci,S., Felaco,M., Grilli,A., Zezza,A., Tenaglia,R. and Federici,G. (1991) Glutathione transferase isoenzymes in normal and neoplastic human kidney tissue. Carcinogenesis, 12, 1471-1475.
30. Shiratori,Y., Soma,Y. and Sato,K. (1987) Immunohistochemical detection of glutathione S-transferase placental (GST-π) form in dysplastic and neoplastic human uterine cervix lesions. Cancer Res., 47, 6806-6809.
31. Niitsu,Y., Takahashi,Y and Saito,T. (1988) Serum GST-π as a tumour marker for gastrointestinal malignancies. Cancer, 63, 317-323.
32. Howie,A.F., Douglas,J.G., Fergusson,R.J. and Beckett,G.J. (1990) Measurement of glutathione S-transferase π isoenzyme in plasma, a possible marker for adenocarcinoma of the lung. Clin. Chem., 36, 453-456.
33. Hirata,S., Odajima,T. and Kohama,G. (1992) Significance of glutathione S-transferase π as a tumour marker in patients with oral cancer. Cancer, 70, 2381-2387.
34. Hao,X.Y., Castro,V.M., Bergh,J., Sandstrom,B. and Mannervik,B. (1994) Isoenzyme-specific quantitative immunoassays for cytosolic glutathione transferases and measurement of the enzymes in blood plasma from cancer patients and in tumour cell lines. Biochim. Biophys. Acta, 1225, 223-230.
35. Ban,N., Takahashi,Y., Takayama,T., Kura,T., Katahira,T., Sakamaki,S. and Niitsu,Y. (1996) Transfection of glutathione S-transferase (GST)-π antisense complementary DNA increases the sensitivity of a colon cancer cell line to adriamycin, cisplatin, melphalan, and etoposide. Cancer Res., 56, 3577-3582.
36. Sugioka,Y., Fujii Kuriyama,Y., Kitagawa,T. and Muramatsu,M. (1985) Changes in polypeptide pattern of rat liver cells during chemical hepatocarcinogenesis. Cancer Res., 45, 365-378.
37. Sakai,M., Okuda,A. and Muramatsu,M. (1988) Multiple regulatory elements and phorbol 12-O-tetradecanoate 13-acetate responsiveness of the rat placental glutathione transferase gene. Proc. Natl Acad. Sci. USA, 85, 9456-9460.
38. Imagawa,M., Osada,S., Okuda,A. and Muramatsu,M. (1991) Silencer binding proteins function on multiple cis-elements in the glutathione transferase P gene. Nucleic Acids Res., 19, 5-10.
39. Morimura,S., Suzuki,T., Hochi,S., Yuki,A., Nomura,K., Kitagawa,T., Nagatsu,I., Imagawa,M. and Muramatsu,M. (1993) Trans-activation of glutathione transferase P gene during chemical hepatocarcinogenesis of the rat. Proc. Natl Acad. Sci. USA, 90, 2065-2068.
40. Fukuda,A., Nakamura,Y., Ohigashi,H., Osawa,T. and Uchida,K. (1997) Cellular response to the redox active lipid peroxidation products: induction of glutathione-S transferase P by 4-hydroxy-2-nonenal. Biochem. Biophys. Res. Commun., 236, 505-509.
41. Bergelson,S., Pinkus,R. and Daniel,V. (1994) Induction of AP-1 (Fos/Jun) by chemical agents mediates activation of glutathione S-transferase and quinone reductase gene expression. Oncogene, 9, 565-571.
42. Schenk,H., Klein,M., Erdbruegger,W., Droege,W. and Schulze-Osthoff,K. (1994) Distinct effects of thioredoxin and antioxidants on the activation of transcription factors NF-κB and AP-1. Proc. Natl Acad. Sci. USA, 91, 1672-1676.