P-glycoprotein expression by technetium-99m-MIBI scintigraphy in hematologic malignancy

Journal of Nuclear Medicine

Volumn 39, Issue 7, 1998, Pages 1191-1197

  Kostakoglu, Lale ^a   Guc, Dicle ^b   Canpinar, Hande ^b   Kars, Ayse ^b   Alper, Eray ^b   Kiratli, Pinar ^b   Hayran, Mutlu ^b   Gündüz, Ufuk ^b   Kansu, Emin ^b  

^a WEILL CORNELL MEDICAL CENTER   (United States)

^b NONE

Author keywords

Flow cytometry; Multidrug resistance; P glycoprotein; Reverse transcription polymerase chain reaction techniques; Technetium 99mMIBI

Indexed keywords

GLYCOPROTEIN P; METHOXY ISOBUTYL ISONITRILE TECHNETIUM TC 99M;

ACUTE GRANULOCYTIC LEUKEMIA; ACUTE LYMPHOBLASTIC LEUKEMIA; ADULT; AGED; ARTICLE; BONE MARROW BIOPSY; CLINICAL ARTICLE; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION; HUMAN; HUMAN CELL; MALE; PRIORITY JOURNAL; QUALITATIVE DIAGNOSIS; QUANTITATIVE DIAGNOSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WHOLE BODY SCINTISCANNING;

FEMALE; FLOW CYTOMETRY; GENES, MDR; HUMANS; LEUKEMIA, LYMPHOCYTIC, ACUTE; LEUKEMIA, MYELOCYTIC, ACUTE; MALE; MIDDLE AGED; P-GLYCOPROTEIN; POLYMERASE CHAIN REACTION; RADIOPHARMACEUTICALS; RNA, MESSENGER; SENSITIVITY AND SPECIFICITY; TECHNETIUM TC 99M SESTAMIBI;

EID: 0031814269     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (33)

1. Fojo AT, Ueda K, Slamon DJ, Poplack DG, Gottesman MM, Pastan I. Expression of a multidrug-resistance gene in human tumors and tissues. Proc Natl Acad Sci USA 1987;84:265-269.
2. Gros P, Talbot F, Tang-Wai D, Bibi E, Kaback HR. Lipophilic cations:a group of model substrates for the multidrug-resistance transporter. Biochemistry 1992;31:1992-1998.
3. Kessel D, Beck WT, Kukuruga D, Schulz V. Characterization of multidrug resistance by fluorescent dyes. Cancer Res 1991;51:4665-4670.
4. Noonan KE, Beck WT, Holzmayer TA, et al. Quantitative analysis of MDR1 (multidrug resistance) gene expression in human tumors by polymerase chain reaction. Proc Natl Acad Sci USA 1990;87:7160-7164.
5. Longo R, Bensi L, Vecchi A, Messora C, Sacchi S. P-glycoprotein expression in acute myeloblastic leukemia analyzed by immunocytochemistry and flow cytometry. Leuk Lymphoma 1995;17:121-125.
6. Ludescher C, Hilbe W, Eisterer W, et al. Activity of p-glycoprotein in B-cell chronic lymphocytic leukemia determined by a flow cytometric assay. J Natl Cancer Inst 1993;85:1751-1758.
7. van der Heyden S, Gheuens E, DeBruijn E, Van Oosterom A, Maes R. P-glycoprotein: clinical significance and methods of analysis. Crit Rev Clin Lab Sci 1995;32:221-264.
8. Benchimol S, Ling V. P-glycoprotein and tumor progression. J Natl Cancer Inst 1994;86:814-816.
9. Rischin D, Ling V. Multidrug resistance in leukemia. In: Freireich EJ, Kantarjian H, eds. Leukemia: advances in research and treatment. Boston, Dordrecht, London: Kluwer Academic Publishers; 1993:269-293.
10. Goldstein LJ, Galski H, Fojo A, et al. Expression of a multidrug resistance gene in human cancers. J Natl Cancer Inst 1989;81:116-124.
11. Marie JP, Zittoun R, Sikic BI. Multidrug resistance (mdr1) gene expression in adult acute leukemias:correlations with treatment outcome and in vitro drug sensitivity. Blood 1991;78:586-592.
12. Piwnica-Worms D, Chiu ML, Budding M, Kronauge JF, Kramer RA, Croop JM. Functional imaging of multidrug-resistant Pgp with an organotechnetium complex. Cancer Res 1993;53:977-984.
13. Rao VV, Chiu ML, Kronauge JF, Piwnica-Worms D. Expression of recombinant human multidrug resistance p-glycoprotein in insect cells confers decreased accumulation of technetium-99m-sestamibi. J Nucl Med 1994;35:510-515.
14. Chiu ML, Kronauge JF, Piwnica-Worms D. Effect of mitochondrial and plasma membrane potentials on accumulation of hexakis (2-methoxyisobutylisonitrile) technetium(I) in cultured mouse fibroblasts. J Nucl Med 1990;31:1646-1653.
15. Piwnica-Worms D, Kronauge JF, Chiu ML. Uptake and retention of hexakis (2-methoxyisobutyl isonitrile) technetium(I) in cultured chick myocardial cells. Mitochondrial and plasma membrane potential dependence. Circulation 1990;82:1826-1838.
16. Duran Cordobes M, Starzes A, Delmon-Moingeon L, et al. Technetium-99m-uptake by human benign and malignant breast tumor cells:correlation with MDR gene expression. J Nucl Med 1996;37:286-289.
17. 99mTc-sestamibi in patients with malignant tumors. J Nucl Med 1997;38:1003-1008.
18. 99mTc-MIBI with the expression of p-glycoprotein in lung cancer. J Nucl Med 1998;39:228-234.
19. Del Vecchio S, Ciarmiello A, Potena MI, et al. In vivo detection of multi-drug resistant (MDR1) phenotype by technetium-99m-sestamibi scan in untreated breast cancer patients. Eur J Nucl Med 1997;24:150-159.
20. Chomcyznski P and Sacchi N. Single step method foe RNA isolation by acid guanidiumthiocyonate-phenol chloroform extraction. Ann Biochem 1979;162:156-159.
21. Nussler V, Pelka Fleischer R, Zwierzina H, et al. Clinical importance of P-glycoprotein-related resistance in leukemia and myelodysplastic syndromes first experience with their reversal. Ann Hematol 1994;69:S25-29.
22. Kuwazuru Y, Yoshimura A, Hanada S, et al. Expression of the multidrug transporter p-glycoprotein in acute leukemia cells and correlation to clinical drug resistance. Cancer 1990;66:868-873.
23. Goasguen JE, Dossot J-M, Fardel O, et al. Expression of the multidrug resistance-associated p-glycoprotein (P-170) in 59 cases of de nove acute lymphoblastic leukemia: prognostic implications. Blood 1993;81:2394-2398.
24. Massart C, Gibassier J, Raoul M, et al. Cyclosporin A, verapamil and S9788 reverse doxorubicin resistance in a human medullary thyroid carcinoma cell line. Anticancer Drugs 1995;6:135-146.
25. Stewart AJ, Canitrot Y, Baracchini E, Dean NM, Deeley RG, Cole SP. Reduction of expression of the multidrug resistance protein (MRP) in human tumor cells by antisense phosphorothioate oooligonucleotides. Biochem Pharmacol 1996;51:461-469.
26. Webb M, Raphael CL, Asbahr H, Erber WN, Meyer BF. The detection of rhodamine 123 efflux at low levels of drug resistance. Br J Haematol 1996;93:650-655.
27. Delville JP, Pradier O, Pauwels O, et al. Comparative study of multidrug resistance evaluated by means of the quantitative immunohistochemical detection of P-glycoprotein and the functional release of rhodamine 123. Am J Hematol 1995;49:183-193.
28. Bailly JD, Muller C, Jaffrezou JP, et al. Lack of correlation between expression and function of p-glycoprotein in acute myeloid leukemia cell lines. Leukemia 1995;9: 799-807.
29. Jain RK. Transport of molecules in the tmor interstitium: a review. Cancer Res 1987;47:3039-3051.
30. Hanson CA. Immunophenotyping of hematologic malignant conditions:to flow or not to flow? Ann J Clin Pathol 1991;96:295-298.
31. Beck WT, Grogan TM, Willman CL, et al. Methods to detect p-glycoprotein-associated multidrug resistance in patients' tumors: consensus recommendations. Cancer Res 1996;56:3010-3020.
32. Melefors O, Hentze MW. Translational regulation by mRNA/protein interactions in eucaryotic cells:ferritin and beyond. Bioassays 1993;15:85-90.
33. Rhoads RE. Regulation of eucaryotic protein synthesis by initiation factors. J Biol Chem 1993;268:3017-3020.