메뉴 건너뛰기




Volumn 20, Issue 3, 1998, Pages 319-324

Analysis of midazolam and metabolites in plasma by high-performance liquid chromatography: Probe of CYP3A

Author keywords

CYP3A; High performance liquid chromatography; Metabolites; Midazolam

Indexed keywords

4 HYDROXYMIDAZOLAM; ALPHA HYDROXYMIDAZOLAM; AMITRIPTYLINE; BENTAZEPAM; BROMAZEPAM; BROTIZOLAM; CAFFEINE; CHLORPROMAZINE; CIMETIDINE; CLOMIPRAMINE; CLONAZEPAM; CLORAZEPATE; CLOZAPINE; CYTOCHROME C OXIDASE; DESIPRAMINE; DIAZEPAM; DOXEPIN; DRUG METABOLITE; EBROTIDINE; FLUNITRAZEPAM; FLUPHENAZINE; HALOPERIDOL; IMIPRAMINE; KETOCONAZOLE; LORAZEPAM; MIDAZOLAM MALEATE; NORTRIPTYLINE; PARACETAMOL; PHENYTOIN; QUINIDINE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

EID: 0031811037     PISSN: 01634356     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007691-199806000-00013     Document Type: Article
Times cited : (74)

References (25)
  • 1
    • 0028237729 scopus 로고
    • Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: Studies with liver microsomes of 30 Japanese and 30 Caucasians
    • Shimada T, Yamazaki H, Mimura M, Inui Y, Guengerich FP. Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians. J Pharmacol Exp Ther 1994;270:414-23.
    • (1994) J Pharmacol Exp Ther , vol.270 , pp. 414-423
    • Shimada, T.1    Yamazaki, H.2    Mimura, M.3    Inui, Y.4    Guengerich, F.P.5
  • 2
    • 0029738490 scopus 로고    scopus 로고
    • First-pass metabolism of midazolam by the human intestine
    • Paine MF, Shen DD, Kunze KL, et al. First-pass metabolism of midazolam by the human intestine. Clin Pharmacol Ther 1996;60: 14-24.
    • (1996) Clin Pharmacol Ther , vol.60 , pp. 14-24
    • Paine, M.F.1    Shen, D.D.2    Kunze, K.L.3
  • 3
    • 0030015297 scopus 로고    scopus 로고
    • Oral first-pass elimination of midazolam involves both gastrointestinal and hepatic CYP3A-mediated metabolism
    • Thummel KE, O'Shea D, Paine MF, et al. Oral first-pass elimination of midazolam involves both gastrointestinal and hepatic CYP3A-mediated metabolism, Clin Pharmacol Ther 1996;59: 491-502.
    • (1996) Clin Pharmacol Ther , vol.59 , pp. 491-502
    • Thummel, K.E.1    O'Shea, D.2    Paine, M.F.3
  • 4
    • 0027477751 scopus 로고
    • A potentially hazardous interaction between erythromycin and midazolam
    • Olkkola KT, Aranko K, Luurila H, et al. A potentially hazardous interaction between erythromycin and midazolam. Clin Pharmacol Ther 1993;53:298-305.
    • (1993) Clin Pharmacol Ther , vol.53 , pp. 298-305
    • Olkkola, K.T.1    Aranko, K.2    Luurila, H.3
  • 5
    • 0028357256 scopus 로고
    • Midazolam should be avoided in patients receiving the systemic antimycotics ketoconazole or itraconazole
    • Olkkola KT, Backman JT, Neuvonen PJ. Midazolam should be avoided in patients receiving the systemic antimycotics ketoconazole or itraconazole. Clin Pharmacol Ther 1994;55:481-5.
    • (1994) Clin Pharmacol Ther , vol.55 , pp. 481-485
    • Olkkola, K.T.1    Backman, J.T.2    Neuvonen, P.J.3
  • 6
    • 0029549892 scopus 로고
    • Effect of fluoxetine, norfluoxetine, sertraline and desmethyl sertraline on human CYP3A catalyzed 1'-hydroxy midazolam formation in vitro
    • Ring BJ, Binkley SN, Roskos L, Wrighton SA. Effect of fluoxetine, norfluoxetine, sertraline and desmethyl sertraline on human CYP3A catalyzed 1'-hydroxy midazolam formation in vitro. J Pharmacol Exp Ther 1995;275:1131-5.
    • (1995) J Pharmacol Exp Ther , vol.275 , pp. 1131-1135
    • Ring, B.J.1    Binkley, S.N.2    Roskos, L.3    Wrighton, S.A.4
  • 7
    • 0029743080 scopus 로고    scopus 로고
    • Midazolam hydroxylation by human liver microsomes in vitro: Inhibition by fluoxetine, norfluoxetine, and by azole antifungal agents
    • Von Moltke LL, Greenblatt DJ, Schmider J, et al. Midazolam hydroxylation by human liver microsomes in vitro: inhibition by fluoxetine, norfluoxetine, and by azole antifungal agents. J Clin Pharmacol 1996;36:783-91.
    • (1996) J Clin Pharmacol , vol.36 , pp. 783-791
    • Von Moltke, L.L.1    Greenblatt, D.J.2    Schmider, J.3
  • 8
    • 0028361593 scopus 로고
    • Inhibition of human CYP3A catalyzed 1'-hydroxy midazolam formation by ketoconazole, nifedipine, erythromycin, cimetidine, and nizatidine
    • Wrighton SA, Ring BJ. Inhibition of human CYP3A catalyzed 1'-hydroxy midazolam formation by ketoconazole, nifedipine, erythromycin, cimetidine, and nizatidine. Pharm Res 1994;11: 921-4.
    • (1994) Pharm Res , vol.11 , pp. 921-924
    • Wrighton, S.A.1    Ring, B.J.2
  • 9
    • 0027996327 scopus 로고
    • Terfenadine metabolism in human liver: In vitro inhibition by macrolide antibiotics and azole antifungals
    • Jurima Romet M, Crawford K, Cyr T, Inaba T. Terfenadine metabolism in human liver: In vitro inhibition by macrolide antibiotics and azole antifungals. Drug Metab Dispos 1994;22:849-57.
    • (1994) Drug Metab Dispos , vol.22 , pp. 849-857
    • Jurima Romet, M.1    Crawford, K.2    Cyr, T.3    Inaba, T.4
  • 11
    • 0029130840 scopus 로고
    • Macrolide antibacterials: Drug interactions of clinical significance
    • Von Rosensteil NA, Adam D. Macrolide antibacterials: Drug interactions of clinical significance. Drug Saf 1995;13:105-22.
    • (1995) Drug Saf , vol.13 , pp. 105-122
    • Von Rosensteil, N.A.1    Adam, D.2
  • 12
    • 0030068752 scopus 로고    scopus 로고
    • Rifampin drastically reduces plasma concentrations and effects of oral midazolam
    • Backman JT, Olkkola KT, Neuvonen PJ. Rifampin drastically reduces plasma concentrations and effects of oral midazolam. Clin Pharmacol Ther 1996;59:7-13.
    • (1996) Clin Pharmacol Ther , vol.59 , pp. 7-13
    • Backman, J.T.1    Olkkola, K.T.2    Neuvonen, P.J.3
  • 13
    • 0028071759 scopus 로고
    • Noninvasive tests of CYP3A enzymes
    • Watkins PB. Noninvasive tests of CYP3A enzymes. Pharmacogenetics 1994;4:171-84.
    • (1994) Pharmacogenetics , vol.4 , pp. 171-184
    • Watkins, P.B.1
  • 14
    • 0026732029 scopus 로고
    • Comparison of urinary 6-β-cortisol and the erythromycin breath test as measures of hepatic P450IIIA (CYP3A) activity
    • Watkins PB, Turgeon DK, Saenger P, et al. Comparison of urinary 6-β-cortisol and the erythromycin breath test as measures of hepatic P450IIIA (CYP3A) activity. Clin Pharmacol Ther 1992;52: 265-73.
    • (1992) Clin Pharmacol Ther , vol.52 , pp. 265-273
    • Watkins, P.B.1    Turgeon, D.K.2    Saenger, P.3
  • 15
    • 0030060304 scopus 로고    scopus 로고
    • Comparison of the dapsone recovery ratio and the erythromycin breath test as in vivo probes of CYP3A activity in patients with rheumatoid arthritis receiving cyclosporine
    • Stein CM, Kinirons MT, Pincus T, Wilkinson GR, Wood AJJ. Comparison of the dapsone recovery ratio and the erythromycin breath test as in vivo probes of CYP3A activity in patients with rheumatoid arthritis receiving cyclosporine. Clin Pharmacol Ther 1996;59:47-51.
    • (1996) Clin Pharmacol Ther , vol.59 , pp. 47-51
    • Stein, C.M.1    Kinirons, M.T.2    Pincus, T.3    Wilkinson, G.R.4    Wood, A.J.J.5
  • 16
    • 0028577492 scopus 로고
    • Population pharmacokinetics of midazolam in neonates
    • Burtin P, Jacqz Aigrain E, Girard P, et al. Population pharmacokinetics of midazolam in neonates. Clin Pharmacol Ther 1994;56: 615-25.
    • (1994) Clin Pharmacol Ther , vol.56 , pp. 615-625
    • Burtin, P.1    Jacqz Aigrain, E.2    Girard, P.3
  • 17
    • 0026629650 scopus 로고
    • Pharmacokinetics of midazolam administered by continuous intravenous infusion to intensive care patients
    • Malacrida R, Fritz ME, Suter PM, Crevoisier C. Pharmacokinetics of midazolam administered by continuous intravenous infusion to intensive care patients. Crit Care Med 1992;20:1123-6.
    • (1992) Crit Care Med , vol.20 , pp. 1123-1126
    • Malacrida, R.1    Fritz, M.E.2    Suter, P.M.3    Crevoisier, C.4
  • 19
    • 0029790347 scopus 로고    scopus 로고
    • Inhibition and kinetics of cytochrome P4503A activity in microsomes from rat, human, and cdna-expressed human cytochrome P450
    • Ghosal A, Satoh H, Thomas PE, Bush E, Moore D. Inhibition and kinetics of cytochrome P4503A activity in microsomes from rat, human, and cdna-expressed human cytochrome P450. Drug Metab Dispos 1996;24:940-7.
    • (1996) Drug Metab Dispos , vol.24 , pp. 940-947
    • Ghosal, A.1    Satoh, H.2    Thomas, P.E.3    Bush, E.4    Moore, D.5
  • 20
    • 0028234586 scopus 로고
    • Regioselective biotransformation of midazolam by members of the human cytochrome P450 3A (CYP3A) subfamily
    • Gorski JC, Hall SD, Jones DR, VandenBranden M, Wrighton SA. Regioselective biotransformation of midazolam by members of the human cytochrome P450 3A (CYP3A) subfamily. Biochem Pharmacol 1994;47:1643-53.
    • (1994) Biochem Pharmacol , vol.47 , pp. 1643-1653
    • Gorski, J.C.1    Hall, S.D.2    Jones, D.R.3    VandenBranden, M.4    Wrighton, S.A.5
  • 21
    • 0029562495 scopus 로고
    • The emerging role of cytochrome P450 3A in psychopharmacology
    • Ketter TA, Flockhart DA, Post RM, et al. The emerging role of cytochrome P450 3A in psychopharmacology. J Clin Psychopharmacol 1995;15:387-98.
    • (1995) J Clin Psychopharmacol , vol.15 , pp. 387-398
    • Ketter, T.A.1    Flockhart, D.A.2    Post, R.M.3
  • 22
    • 0029126498 scopus 로고
    • Cyclosporine and liver transplantation: Will the midazolam test make blood level monitoring obsolete?
    • Watkins PB. Cyclosporine and liver transplantation: will the midazolam test make blood level monitoring obsolete? Hepatology 1995;2:994-6.
    • (1995) Hepatology , vol.2 , pp. 994-996
    • Watkins, P.B.1
  • 23
    • 0028847788 scopus 로고
    • The erythromycin breath test predicts the clearance of midazolam
    • Lown KS, Thummel KE, Benedict PE, et al. The erythromycin breath test predicts the clearance of midazolam. Clin Pharmacol Ther 1995;57:16-24.
    • (1995) Clin Pharmacol Ther , vol.57 , pp. 16-24
    • Lown, K.S.1    Thummel, K.E.2    Benedict, P.E.3
  • 24
    • 0028114619 scopus 로고
    • Use of midazolam as a human cytochrome P450 3a probe, I: In vitro-in vivo correlations in liver transplant patients
    • Thummel KE, Shen DD, Podoll TD, et al. Use of midazolam as a human cytochrome P450 3A probe, I: In vitro-in vivo correlations in liver transplant patients. J Pharmacol Exp Ther 1994;271:549-56.
    • (1994) J Pharmacol Exp Ther , vol.271 , pp. 549-556
    • Thummel, K.E.1    Shen, D.D.2    Podoll, T.D.3
  • 25
    • 0027244966 scopus 로고
    • Determination of midazolam and its a-hydroxymetabolite in human plasma and urine by high-performance liquid chromatography
    • Ha HR, Rentsch KM, Kneer J, Vonderschmitt DJ. Determination of midazolam and its a-hydroxymetabolite in human plasma and urine by high-performance liquid chromatography. Ther Drug Monit 1993;15:338-43.
    • (1993) Ther Drug Monit , vol.15 , pp. 338-343
    • Ha, H.R.1    Rentsch, K.M.2    Kneer, J.3    Vonderschmitt, D.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.