Natural competence for DNA transformation in Helicobacter pylori: Identification and genetic characterization of the comB locus

Molecular Microbiology

Volumn 28, Issue 5, 1998, Pages 1027-1038

  Hofreuter, Dirk ^a,b   Odenbreit, Stefan ^a,b   Henke, Gabriele ^a,c   Haas, Rainer ^a,b  

^a MAX PLANCK INST FÜR BIOLOGIE   (Germany)

^b UNIVERSITY OF MUNICH   (Germany)

^c DPC Biermann   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL DNA;

AMINO ACID SEQUENCE; ARTICLE; BACTERIAL GENE; BACTERIUM TRANSFORMATION; GENE LOCUS; HELICOBACTER PYLORI; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PRIORITY JOURNAL; TRANSPOSON;

AGROBACTERIUM TUMEFACIENS; ANIMALIA; BACTERIA (MICROORGANISMS); BORDETELLA PERTUSSIS; HELICOBACTER PYLORI; NEGIBACTERIA; PROKARYOTA; PSEUDOMONAS; PSEUDOMONAS AERUGINOSA;

EID: 0031808471     PISSN: 0950382X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2958.1998.00879.x     Document Type: Article

References (47)

1. Alt-Mörbe, J., Stryker, J.L., Fuqua, C., Li, P.L., Farrand, S.K., Winans, S.C. (1996) The conjugal transfer system of Agrobacterium tumefaciens octopine-type Ti plasmids is closely related to the transfer system of an IncP plasmid and distantly related to Ti plasmid vir genes. J Bacteriol 178: 4248-4257.
2. Akopyanz, N., Bukanov, N., Westblom, T.U., and Berg, D.E. (1992) PCR-based RFLP analysis of DNA sequence diversity in the gastric pathogen Helicobacter pylori. Nucleic Acids Res 20: 6221-6225.
3. Blaser, M.J. (1992) Hypotheses on the pathogenesis and natural history of Helicobacter pylori induced inflammation. Gastroenterotogy 102: 720-727.
4. Boyer, H.W., and Roulland-Dussoix, D. (1969) A complementation analysis of the restriction and modification of DNA in Escherichia coli. J Mol Biol 41: 459-472.
5. Bukanov, N.O., and Berg, D.E. (1994) Ordered cosmid library and high-resolution physical- genetic map of Helicobacter pylori strain NCTC11638. Mol Microbiol 11: 509-523.
6. Chandler, M.S., and Morrison, D.A. (1987) Competence for genetic transformation in Streptococcus pneumoniae: molecular cloning of com, a competence control locus. J Bacteriol 169: 2005-2011.
7. Cover, T.L., and Blaser, M.J. (1992) Purification and characterization of the vacuolating toxin from Helicobacter pylori. J Biol Chem 267: 10570-10575.
8. Dreiseikelmann, B. (1994) Translocation of DNA across bacterial membranes. Microbiol Rev 58: 293-316.
9. Dubnau, D. (1991) Genetic competence in Bacillus subtilis. Microbiol Rev 55: 395-424.
10. Dubois, A., Fiala, N., Hemanackah, L.M., Drazek, E.S., Tarnawski, A., Fishbein, W.N., et al. (1994) Natural gastric infection with Helicobacter pylori in monkeys: a model for spiral bacteria infection in humans. Gastroenterology 106: 1405-1417.
11. Figurski, D.H., and Helinski, D.R. (1979) Replication of an origin-containing derivative of plasmid RK2 dependent on a plasmid function provided in trans. Proc Natl Acad Sci USA 76: 1648-1652.
12. Haas, R., Meyer, T.F., and van Putten, J.P.M. (1993a) Aflagellated mutants of Helicobacter pylori generated by genetic transformation of naturally competent strains using transposon shuttle mutagenesis. Mol Microbiol 8: 753-760.
13. Haas, R., Kahrs, A.F., Facius, D., Allmeier, H., Schmitt, R., and Meyer, T.F. (1993b) TnMax - a versatile mini-transposon for the analysis of cloned genes and shuttle mutagenesis. Gene 130: 23-31.
14. Havarstein, L.S., Coomaraswamy, G., and Morrison, D.A. (1995) An unmodified heptadecapeptide pheromone induces competence for genetic transformation in Streptococcus pneumoniae. Proc Natl Acad Sci USA 92: 11140-11144.
15. Hofmann, K., and Stoffel, W. (1993) TMbase - a database of membrane spanning proteins segments. Biol Chem Hoppe-Seyler 347: 166.
16. Kahrs, A.F., Odenbreit, S., Schmitt, W., Heuermann, D., Meyer, T.F., and Haas, R. (1995) An improved TnMax mini-transposon system suitable for sequencing, shuttle mutagenesis and gene fusions. Gene 167: 53-57.
17. Labigne, A., Cussac, V., and Courcoux, P. (1991) Shuttle cloning of genes responsible for urease activity from Helicobacter pylori and nucleotide sequence determination. J Bacteriol 173: 1920-31.
18. Lessl, M., Balzer, D., Pansegrau, W., and Lanka, E. (1992) Sequence similarities between the RP4 Tra2 and the Ti VirB region strongly support the conjugation model for T-DNA transfer. J Biol Chem 267: 20471-20480.
19. Leying, H., Suerbaum, S., Geis, G., and Haas, R. (1992) Characterisation of flaA, a Helicobacter pylori flagellin gene. Mol Microbiol 6: 2863-2874.
20. Lupas, A., Van Dyke, M., Stock, J. (1991) Predicting coiled coils from protein sequences. Science 252: 1162-1164.
21. Lorenz, M.G., and Wackernagel, W. (1994) Bacterial gene transfer by natural genetic transformation in the environment. Microbiol Rev 58: 563-602.
22. Lyras, D., Palombo, E.A., and Stanisich, V.A. (1992) Characterization of a Tra 2 function of RP1 that affects growth of Pseudomonas aeruginosa PAO and surface exclusion in Escherichia coli K12. Plasmid 27: 105-118.
23. Magnuson, R., Solomon, J., and Grossman, A.D. (1994) Biochemical and genetic characterization of a competence pheromone from B. subtilis. Cell 77: 207-216.
24. Majewski, S.I.H., and Goodwin, C.S. (1988) Restriction endonuclease analysis of the genome of Campylobacter pylori with a rapid extraction method: evidence for considerable genomic variation. J Infect Dis 157: 465-471.
25. Marshall, B.J., and Warren, J.R. (1984) Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration. Lancet i: 1311-1315.
26. Nedenskov-Sorensen, P., Bukholm, G., and Bovre, K. (1990) Natural competence for genetic transformation in Campylobacter pylori. J Infect Dis 161: 365-366.
27. Nomura, A., Stemmermann, G.N., Chyou, P.H., Kato, I., Perez-Perez, G.I., and Blaser, M.J. (1991) Helicobacter pylori infection and gastric carcinoma among Japanese Americans in Hawaii. N Engl J Med 325: 1132-1136.
28. Odenbreit, S., Till, M., and Haas, R. (1996) Optimized BlaM-transposon shuttle mutagenesis of Helicobacter pylori allows the identification of novel genetic loci involved in bacterial virulence. Mol Microbiol 20: 361-373.
29. Parsonnet, J., Friedman, G.D., Vandersteen, D.P., Chang, Y., Vogelman, J.H., Orentreich, N., and Sibley, R.K. (1991) Helicobacter pylori infection and the risk of gastric carcinoma. N Engl J Med 325: 1127-1131.
30. Pifer, M.L., and Smith, H.O. (1985) Processing of donor DNA during Haemophilus influenzae transformation: analysis using a model plasmid system. Proc Natl Acad Sci USA 82: 3731-3735.
31. Pohlner, J., Krämer, J., and Meyer, T.F. (1993) A plasmid system for high-level expression and in vitro processing of recombinant proteins. Gene 130: 121-126.
32. Sambrook, J., Fritsch, E.F., and Maniatis, T. (1989) Molecular Cloning: a Laboratory Manual. Cold Spring Harbor Laboratory, NY: Cold Spring Harbor Laboratory Press.
33. Sanger, F., Nicklen, S., and Coulson, A.R. (1977) DNA sequencing with chain-terminating inhibitors. Proc Natl Acad Sci USA 74: 5463-5467.
34. Schmitt, W., and Haas, R. (1994) Genetic analysis of the Helicobacter pylori vacuolating cytotoxin: structural similarities with the IgA protease type of exported protein. Mol Microbiol 12: 307-319.
35. Schmitt, W., Odenbreit, S., Heuermann, D., and Haas, R. (1995) Cloning of the Helicobacter pylori recA gene and functional characterization of its product. Mol Gen Genet 248: 563-572.
36. Shine, J., and Dalgarno, L. (1974) The 3′-terminal sequence of Escherichia coli 16S ribosomal RNA: complementarity to nonsense triplets and ribosome binding sites. Proc Natl Acad Sci USA 71: 1342-1346.
37. Solomon, J.M., and Grossman, A.D. (1996) Whos competent and when: regulation of natural genetic competence in bacteria. Trends Genet 12: 150-155.
38. Sparling, P.F. (1966) Genetic transformation of Neisseria gonorrhoeae to streptomycin resistance. J Bacteriol 92: 1364-1370.
39. Tomb, J.-F., White, O., Kerlavage, A.R., Clayton, R.A., Sutton, G.G., Fleischmann, R.D., et al. (1997) The complete genome sequence of the gastric pathogen Helicobacter pylori. Nature 388: 539-547.
40. Vogel, H., and Jähnig, F. (1986) Models for the structure of outer-membrane proteins of Escherichia coli derived from raman spectroscopy and prediction methods. J Mol Biol 190: 191-199.
41. von Heinje, G. (1985) Structural and thermodynamic aspects of the transfer of proteins into and across membranes. Curr Top Membr Transp 24: 151-179.
42. Wadström, T., Ascencio, F., Ljungh, A., Lelwala-Guruge, J., Ringnér, M., Utt, M., and Valkonen, K. (1993) Helicobacter pylori adhesins. Eur J Gastroenterol Hepatol 5 (suppl. 2): S12-S15.
43. Wang, Y., and Taylor, D.E. (1990) Natural transformation in Campylobacter species. J Bacteriol 172: 949-955.
44. Ward, J.E., Akiyoshi, D.E., Regier, D., Datta, A., Gordon, M.P., and Nester, E.W. (1988) Characterization of the virB operon from an Agrobacterium tumefaciens Ti plasmid. J Biol Chem 263: 5804-5814.
45. Weiss, AA., Johnson, FD., Burns, DL. (1993) Molecular characterization of an operon required for pertussis toxin secretion. Proc Natl Acad Sci USA 90: 2970-2974.
46. Winans, S.C., Burns, D.L., and Christie, P.J. (1996) Adaptation of a conjugal transfer system for the export of pathogenic macromolecules. Trends Microbiol 4: 64-68.
47. Wotherspoon, A.C., Doglioni, C., Diss, T.C., Pan, L., Moschini, A., De-Boni, M., and Isaacson, P.G. (1993) Regression of primary low-grade B-cell gastric lymphoma of mucosa-associated lymphoid tissue type after eradication of Helicobacter pylori. Lancet 342: 575-577.