Fibronectin mRNA alternative splicing is temporally and spatially regulated during chondrogenesis in vivo and in vitro

Developmental Dynamics

Volumn 206, Issue 2, 1996, Pages 219-230

  Gehris, Amy L ^a   Oberlender, Steven A ^a   Shepley, Kenneth J ^a   Tuan, Rocky S ^a   Bennett, Vickie D ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

Alternative splicing; Cartilage; Chondrogenesis; Fibronectin; In situ hybridization; Limb development

Indexed keywords

FIBRONECTIN; MESSENGER RNA;

ALTERNATIVE RNA SPLICING; ANIMAL TISSUE; ARTICLE; CARTILAGE; CHICKEN; CHONDROGENESIS; EXON; GENE EXPRESSION; IN SITU HYBRIDIZATION; LIMB; MESENCHYME; NONHUMAN; PRIORITY JOURNAL; SPATIAL ORIENTATION; TIME PERCEPTION;

ALTERNATIVE SPLICING; ANIMALS; CARTILAGE; CELLS, CULTURED; CHICK EMBRYO; EXONS; FIBRONECTINS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; IN SITU HYBRIDIZATION; LIMB BUD; OLIGONUCLEOTIDE PROBES; RNA, MESSENGER; TIME FACTORS;

EID: 0029898273     PISSN: 10588388     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0177(199606)206:2<219::AID-AJA11>3.0.CO;2-Y     Document Type: Article

References (58)

1. Ahrens, P.B., Solursh, M., and Reiter, R.S. (1977) Stage-related capacity for limb chondrogenesis in cell culture. Dev. Biol. 60:69-82.
2. Albelda, S.M., and Buck, C.A. (1990) Integrins and other cell adhesion molecules. FASEB J. 4:2868-2880.
3. Bennett, V.D., Pallante, K.M., and Adams, S.L. (1991) The splicing pattern of fibronectin mRNA changes during chondrogenesis resulting in an unusual form of the mRNA in cartilage. J. Biol. Chem. 266(9):5918-5924.
4. Clemmenson, I., Holund, B. Johansen, N., and Andersen, R.B. (1982) Demonstration of fibronectin in human articular cartilage by an indirect immunoperoxidase technique. Histochemistry 76:51-56.
5. Coutinho, L.L., Morris, J., and Invarie, R. (1992) Whole mount in situ detection of low abundance transcripts of the myogenic factor qmfI and myosin heavy chain protein in quail embryos. Biotechniques 13(5):722-724.
6. Crabb, I.D., Hughes, S.S., Hicks, D.G., Puzas, J.E., Tsao, G.J.Y., and Rosier, R.N. (1992) Non-radioactive in situ hybridization using digoxigenin-labeled oligonucleotides. Am. J. Pathol. 141(3):579-589.
7. Dessau, W., Sasse, J., Timpl, R., Jilek, F., and von der Mark, K. (1978) Synthesis and extracellular deposition of fibronectin in chondrocyte cultures. J. Cell Biol. 79:342-355.
8. Dessau, W., von der Mark, H., von der Mark, K., and Fischer, S. (1980) Changes in the patterns of collagens and fibronectin during limbbud chondrogenesis. J. Embryol. Exp. Morphol. 57:51-60.
9. DeSimone, D.W., Norton, P.A., and Hynes, R.O. (1992) Identification and characterization of alternatively spliced fibronectin mRNAs expressed in early Xenopus embryos. Dev. Biol. 149(2):357-369.
10. Ede (1983) Cellular condensation and chondrogenesis. In: "Cartilage: Development, Differentiation, and Growth 2," Hall, B.K. (ed). New York: Academic Press, pp 143-185.
11. Evans, M.M.S., and Tuan, R.S. (1988) Cellular condensation and collagen type II expression during chondrogenesis in vitro. J. Cell Biol. 107:163a.
12. ffrench-Constant, C., and Hynes, R. (1988) Patterns of fibronectin gene expression and splicing during cell migration in chicken embryos. Development 104:369-382.
13. ffrench-Constant, C., and Hynes, R. (1989) Alternative splicing of fibronectin is temporally and spatially regulated in the chicken embryo. Development 106:375-388.
14. Frenz, D.A., Akiyama, S.K., Paulsen, D.F., and Newman, S.A. (1989a) Latex beads as probes of cell-surface extracellular matrix interactions during chondrogenesis: evidence for a role for aminoterminal heparin-binding domain of fibronectin. Dev. Biol. 136:87-96.
15. Frenz, D.A., Jaikaria, N.S., and Newman, S.A. (1989b) The mechanism of precartilage mesenchymal condensation: A major role for interaction of the cell surface with the amino-terminal heparin-binding domain of fibronectin. Dev. Biol. 136:97-103.
16. Glant, T.T., Hadhazy, C., Mikecz, K., and Sipos, A. (1985) Appearance and persistence of fibronectin in cartilage. Specific interaction of fibronectin with collagen type II. Histochemistry 82:149-158.
17. Hamburger, V., and Hamilton, H.L. (1951) A series of normal stages in the development of the chick embryo. J. Morphol. 33:49-92.
18. Hynes, R.O. (1990) "Fibronectins." New York: Springer-Verlag.
19. Hynes, R.O. (1992) Integrins: a family of cell surface receptors. Cell 48:549-554.
20. Knudson, C.B. (1993) Hyaluronan receptor-directed assembly of chondrocyte pericellular matrix. J. Cell Biol. 120:825-834.
21. Knudson, C.B., and Toole, B.P. (1985) Changes in the pericellular matrix during differentiation of limb bud mesenchyme. Dev. Biol. 112:308-318.
22. Knudson, C.B., and Toole, B.P. (1987) Hyaluronate-cell interactions during differentiation of chick embryo limb mesenchyme. Dev. Biol. 124:82-90.
23. Kornblihtt, A.R., Vibe-Pedersen, K., and Baralle, F.E. (1984) Human fibronectin: cell specific alternative mRNA splicing generates polypeptide chains differing in the number of internal repeats. Nucleic Acids Res. 12:5853-5868.
24. Kosher, R.A., Walker, K.H., and Ledger, P.W. (1982) Temporal and spatial distribution of fibronectin during development of the embryonic chick limb bud. Cell Differ. 11:217-228.
25. Kuettner, K.E. (1992) Biochemistry of articular cartilage in health and disease. Clin. Biochem. 25:155-163.
26. Kulyk, W.M., Upholt, W.B., and Kosher, R.A. (1989) Fibronectin gene expression during limb cartilage differentiation. Development 106: 449-455.
27. Linsenmayer, T.F., Toole, B.P., and Trelstad, R.L. (1973) Temporal and spatial transitions in collagen types during embryonic chick limb development. Dev. Biol. 35:232-239.
28. Mackie, E.J. (1987) Tenascin is associated with chondrogenic and osteogenic differentiation in vivo and promotes chondrogeneeis in vitro. J. Cell Biol. 105:2569-2579.
29. Magnuson, V.L., Young, M., Schattenberg, D.G., Mancini, M.A., Chen, D., Steffensen, B., and Klebe, R.J. (1991) The alternative splicing of fibronectin pre-mRNA is altered during aging and in response to growth factors. J. Biol. Chem. 266:14654-14662.
30. Mayne, R. (1989) Cartilage collagens: What is their function, and are they involved in articular disease? Arthritis Rheum. 32:241-246.
31. Melnick, M., Jaskoll, T., Brownell, A.G., MacDougall, M., Bessem, C., and Slavkin, H.C. (1981) Spatiotemporal patterns of fibronectin distribution during embryonic development. I. Chicken limbs. J. Embryol. Exp. Morphol. 63:193-206.
32. Melton, D.A., Krieg, P.A., Rebagliati, M.R., Maniatis, T., Zinn, K., and Green M.R. (1984) Nucleic Acids Res. 12:7035-7056.
33. Mosher, D.F. (1989) "Fibronectins." New York: Academic Press.
34. Nah, H.-D., and Upholt, W.B. (1991) Type II collagen mRNA containing an alternatively spliced exon predominates in the chick limb prior to chondrogenesis. J. Biol. Chem. 266:23446-23452.
35. Nah, H.-D., Rodgers, B.J., Kulyk, W.M., Kream, B.E., Kosher, R.A., and Upholt, W.B. (1988) In situ hybridization analysis of the expression of the type II collagen gene in the developing chicken limb bud. Collagen Rel. Res. 8:277-294.
36. Newman, S.A., Frenz, D.A., Tomasek, J.J., and Rabuzzi, D.D. (1985) Matrix-driven translocation of cells and non-living particles. Science 228:885-889.
37. Newman, S.A., Frenz, D.A., Hasegawa, E., and Akiyama, S.K. (1987) Matrix-driven translocation: dependence on interaction of aminoterminal domain of fibronectin with heparin-like surface components of cells or particles. Proc. Natl. Acad. Sci. U.S.A. 84:4791-4795.
38. Norton, P.A., and Hynes, R.O. (1987) Alternative splicing of chicken fibronectin in embryos and in normal and transformed cells. Mol. Cell. Biol. 7:4297-4307.
39. Oberlender, S.A., and Tuan, R.S. (1994a) Spatiotemporal profile of N-cadherin expression in the developing limb mesenchyme. Cell Adhesion Commun. 2:521-537.
40. Oberlender S.A., and Tuan, R.S. (1994b) Expression and functional involvement of N-cadherin in embryonic limb chondrogenesis. Development 120:177-187.
41. Odermatt, E., Tamkun, J.W., and Hynes, R.O. (1985) The repeating modular structure of the fibronectin gene: relationship to protein structure and subunit variation. Proc. Natl. Acad. Sci. U.S.A. 82: 6571-6575.
42. Pagani, F., Zagato, L., Vergani, D., Casari, G., Sidoli, A. and Baralle, F.E. (1991) Tissue-specific splicing patterns of fibronectin messenger RNA precursors during development and aging. J. Cell Biol. 113(5):1223-1229.
43. San Antonio, J.D., and Tuan, R.S. (1986) Chondrogenesis in the limb bud mesenchyme in vitro: Stimulation by cations. Dev. Biol. 115: 313-324.
44. Sandell, L.J., Morris, N., Robbin, J.R., and Goldring, M.B. (1991) Alternatively spliced type II collagen mRNAs define distinct populations of cells during vertebral development: differential expression of the amino-propeptide. J. Cell Biol. 114(6):1307-1319.
45. Sanger, F., Nicklen, S., and Coulson, A.R. (1977) DNA sequencing with chain-terminating inhibitors. Proc. Natl. Acad. Sci. U.S.A. 74: 5463-5467.
46. Saunders, J.W., Jr. (1948) The proximo-distal sequence of origin of the parts of the chick wing and the role of the ectoderm. J. Exp. Zool. 108:363-403.
47. Schwarzbauer, J.E., Tamkun, J.W., Lemischka, I.R., and Hynes, R.O. (1983) Three different fibronectin mRNAs arise by alternative splicing within the coding region. Cell 35:421-431.
48. Schwarzbauer, J.E., Patel, R.S., Fonda, D., and Hynes, R.O. (1987) Multiple sites of alternative splicing of the rat fibronectin gene transcript. EMBO J. 6:2573-2580.
49. Searls, R. (1973) In: "Developmental Regulation," Conrad S.J. (ed). New York: Academic Press, pp. 219-250.
50. Solursh, M. (1983) Cell-cell interactions and chondrogenesis. In: "Cartilage: Development, Differentiation and Growth." Hall, B.K. (ed). New York: Academic Press, pp. 121-141.
51. Swalla, B.J., Upholt, W.B., and Solursh, M. (1988) Analysis of type II collagen RNA localization in chick wing buds by in situ hybridization. Dev. Biol. 125:51-58.
52. Tavella, S., Raffo, P. Taccheti, C., Cancedda, R., and Castagnola, P. (1994) N-CAM and N-cadherin expression during in vitro chondrogenesis. Exp. Cell Res. 215:354-362.
53. Thorogood, P.V., and Hinchliffe, J.R. (1975) An analysis of the condensation process during chondrogenesis in the embryonic hind limb. J. Embryol. Exp. Morphol. 33:581-606.
54. Tomasek, J.J., Mazurkiewicz, J.E., and Newman, S.A. (1982) Nonuniform distribution of fibronectin during avian limb development. Dev. Biol. 90:118-126.
55. Widelitz, R.B., Jiang, T.X., Murray, B.J., and Chuong, C.M. (1993) Adhesion molecules in skeletogenesis: II. Neural cell adhesion molecules mediate precartilagenous mesenchymal condensations and enhance chondrogenesis. J. Cell. Physiol. 156:399-411.
56. Wurster, N.B., and Lust, G. (1982) Fibronectin in osteoarthritic canine articular cartilage. Biochem. Biophys. Res. Commun. 109: 1094-1101.
57. Young, M.F., Vogeli, G., Nunez, A.M., Fernandez, M.P., Sullivan, M., and Sobel, M.E. (1984) Isolation of cDNA and genomic DNA clones encoding type II collagen. Nucl. Acids Res. 12:4207-4228.
58. Zardi, L., Carnemolla, B., Siri, A., Petersen, I.E., Paolella, G., Sebastio, G., and Baralle, F.E. (1987) Transformed human cells produce a new fibronectin isoform by preferential alternative splicing of a previously unobserved exon. EMBO J. 6:2337-2342.