7-(2-Aminomethyl-1-azetidinyl)-4-oxoquinoline-3-carboxylic acids as potent antibacterial agents: Design, synthesis, and antibacterial activity

Chemical and Pharmaceutical Bulletin

Volumn 46, Issue 5, 1998, Pages 787-796

  Fujita, Masahiro ^a   Chiba, Katsumi ^a   Tominaga, Yukio ^a   Hino, Katsuhiko ^a  

^a DAINIPPON SUMITOMO PHARMA CO LTD   (Japan)

Author keywords

2 Aminomethylazetidine; Antibacterial activity; Asymmetric induction; Quinolone

Indexed keywords

1 PIPERIDINYL QUINOLONE; 1 PYRROLIDINYL QUINOLONE; 5 AMINO 6,8 DIFLUOROQUINOLINE; 7 (2 AMINOMETHYL 1 AZETIDINYL) 4 OXOQUINOLINE 3 CARBOXYLIC ACID; ANTIINFECTIVE AGENT; PIPERIDINE DERIVATIVE; QUINOLINE DERIVATIVE; QUINOLONE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; CHIRALITY; DRUG DESIGN; DRUG MECHANISM; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; ENANTIOMER; ESCHERICHIA COLI; MINIMUM INHIBITORY CONCENTRATION; MOLECULAR MODEL; OPTICAL RESOLUTION; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS AUREUS; STRUCTURE ACTIVITY RELATION;

EID: 0031805061     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.46.787     Document Type: Article

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