Species variation in pharmacokinetics and opsonization of palmitoyl rhizoxin (RS-1541) incorporated in lipid emulsions

Journal of Drug Targeting

Volumn 5, Issue 6, 1998, Pages 491-505

  Kurihara, Atsushi ^a   Shibayama, Yoko ^a   Kasuya, Akiko ^a   Ikeda, Masaru ^a   Hisaoka, Masafumi ^a  

^a DAIICHI SANKYO CO   (Japan)

Author keywords

Emulsions; Opsonization; Pharmacokinetics; RS 1541 (palmitoyl rhizoxin); Species variation

Indexed keywords

LIPID EMULSION; RHIZOXIN; RICINOMACROGOL; RS 1541; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOG; DRUG CLEARANCE; DRUG ELIMINATION; DRUG UPTAKE; EMULSION; INTRAVENOUS DRUG ADMINISTRATION; MALE; MOUSE; NONHUMAN; OPSONIZATION; PRIORITY JOURNAL; RABBIT; RAT; SPECIES DIFFERENTIATION;

EID: 0031796843     PISSN: 1061186X     EISSN: None     Source Type: Journal    
DOI: 10.3109/10611869808997875     Document Type: Article

References (27)

1. Clark S. B. and Derksen A. (1987) Phosphatidylcholine composition of emulsions influences triacylglycerol lipolysis and clearance from plasma. Biochim. Biophys. Acta, 920, 37-46.
2. Couvreur P., Roblot-Treupel L., Poupon M. F., Brasseur F. and Puisieux F. (1990) Nanoparticles as microcarriers for anticancer drugs. Adv. Drug Del. Rev., 5, 209-230.
3. Harashima H., Ohnishi Y, and Kiwada H. (1992) In vivo evaluation of the effect of the size and opsonization on the hepatic extraction of liposomes in rats: an application of Oldendorf method. Biopharm. Drug Disposit., 13, 549-553.
4. Harashima H., Sakata K., Funato K. and Kiwada H. (1994) Enhanced hepatic uptake of liposomes through complement activation depending on the size of liposomes. Pharm. Res., 11, 402-406.
5. Harashima H., Komatsu S., Kojima S., Yanagi C., Morioka Y., Naito M. and Kiwada H. (1996) Species difference in the disposition of liposomes among mice, rats, and rabbits: allometric relationship and species dependent hepatic uptake mechanism. Pharm. Res., 13, 1049-1054.
6. Hultin M., Bengtsson-Olivecrona G. and Olivecrona T. (1992) Release of lipoprotein lipase to plasma by triacylglycerol emulsions: Comparison to the effect of heparin. Biochim. Biophys, Acta, 1125, 97-103.
7. Iwasaki S., Kobayashi H., Furukawa J., Namikoshi M., Okuda S., Sata Z., Matsuda I. and Noda T. (1984) Studies on macrocyclic lactone antibiotics, VII. Structure of phytotoxin "Rhizoxin" produced by Rhizopus chinensis. J. Antibiotics, 37, 354-362.
8. Juliano R. L. (1988) Factors affecting the clearance kinetics and tissue distribution of liposomes, microspheres and emulsions. Adv. Drug Del. Rev., 2, 31-54.
9. Kobayashi T., Sasagawa K., Hirai K., Nishimura T., Tsuruo T., Iwasaki S., Tsukagoshi S. and Okuda S. (1989) Antitumor activities of new antitumor antibiotic derivatives, acylated rhizoxins. In Abstracts of the 16th International Congress of Chemotherapy, Jerusalem, Israel, pp. 739. 1-2.
10. Kurihara A., Naganuma H., Hisaoka M., Tokiwa H. and Kawahara Y. (1992) Prediction of human pharmacokinetics of panipenembetamipron from animal data. Antimicrob. Agents Chemother., 36, 1810-1816.
11. Kurihara A., Shibayama Y., Mizota A., Yasuno A., Ikeda M., Sasagawa K., Kobayashi T. and Hisaoka M. (1996a) Lipid emulsions of palmitoyl rhizoxin: effects of composition on lipolysis and biodistribution. Biopharm. Drug Disposit., 17, 331-342.
12. Kurihara A., Shibayama Y., Mizota A., Yasuno A., Ikeda M., Sasagawa K.. Kobayashi T. and Hisaoka M. (1996b) Enhanced tumor delivery and antitumor activity of palmitoyl rhizoxin using stable lipid emulsions in mice. Pharm Res., 13, 305-310.
13. Kurihara A., Shibayama Y., Yasuno A., Ikeda M. and Hisaoka M. (1996c) Lipid emulsions of palmitoyl rhizoxin: effects of particle size on blood dispositions of emulsion lipid and incorporated compound in rats. Biopharm. Drug Disposit., 17, 343-353.
14. Kurihara A., Shibayama Y., Mizota A., Yasuno A., Ikeda M. and Hisaoka M. (1996d) Pharmacokinetics of highly lipophilic antitumor agent palmitoyl rhizoxin incorporated in lipid emulsions in rats. Biol. Pharm. Bull., 19, 252-258.
15. Liu D., Mori A. and Huang L. (1992) Role of liposome size and RES blockade in controlling biodistribution and tumor uptake of GM1-containing liposomes. Biochim. Biophys. Acta, 1104, 95-101.
16. Muller R. H. (1991) In vivo distribution of carriers. In Muller, R. H., Colloidal Carriers for Controlled Drug Delivery and Targeting, CRC Press, Boston, pp. 211-276.
17. Nakanishi A., Naganuma H., Kondo J., Watanabe K., Hirano K., Kawasaki T. and Kawahara Y. (1992) 3-Bromomethyl-7-methoxy-1,4-benzoxazin-2-one as a highly sensitive fluorescence derivatization reagent for carboxylic acids in highperformance liquid chromatography. J. Chromatogr., 591, 159-164.
18. Sakaeda T., Takahashi K., Nishihara Y. and Hirano K. (1994) O/W lipid emulsions for parenteral drug delivery. I. pharmacokinetics of the oil particles and incorporated sudan II. Biol. Pharm. Bull., 17, 1490-1495.
19. Sakaeda T. and Hirano K. (1995) O/W lipid emulsions for parenteral drug delivery. II. effect of composition on pharmacokinetics of incorporated drug. J. Drug Targeting, 3, 221-230.
20. Sasaki H., Kakutani T., Hashida M. and Sezaki H. (1986) Characterization of liposomes and an emulsion containing mitomycin C or lipophilic mitomycin C prodrugs. J. Pharm. Sci., 75, 1166-1170.
21. Sato Y., Kiwada H. and Kato Y. (1986) Effect of dose and vesicle size on the pharmacokinetics of liposomes. Chem. Pharm. Bull., 34, 4244-4252.
22. Sekine M., Sasahara K., Okada R. and Awazu S. (1985) Improvement of bioavailability of poorly absorbed drugs. IV.: Mechanism of the promoting effect of medium chain glyceride on the rectal absorption of water soluble drugs. J. Pharmacobio-Dyn., 8, 645-652.
23. Takahashi M., Iwasaki S., Kobayashi H., Okuda S., Murai T. and Sato Y. (1987) Rhizoxin binding to tubulin at the maytansine-binding site. Biochim. Biophys. Acta, 926, 215-223.
24. Takino T., Nakajima C., Takakura Y., Sezaki H. and Hashida M. (1993) Controlled biodistribution of highly lipophilic drugs with various parenteral formulations. J. Drug Targeting, 1, 117-124.
25. Takino T., Konishi K., Takakura Y. and Hashida M. (1994) Long circulating emulsion carrier systems for highly lipophilic drugs. Biol. Pharm. Bull., 17, 121-125.
26. Takino T., Nagahama E., Sakaeda T., Yamashita F., Takakura Y. and Hashida M. (1995) Pharmacokinetic disposition analysis of lipophilic drugs injected with various lipid carriers in the singlepass rat liver perfusion system. Int. J. Pharm., 114, 43-54.
27. Yamaguchi T., Tanabe N., Fukushima Y., Nasu T. and Hayashi H. (1994) Distribution of prostaglandin El in lipid emulsion in relation to release rate from lipid particles. Chem, Pharm, Bull., 42, 646-650.