Thalamocortical circuits causing remote hypometabolism during focal interictal epilepsy

Epilepsy Research

Volumn 32, Issue 3, 1998, Pages 379-387

  Bruehl, C ^a   Wagner, U ^b   Huston, J P ^b   Witte, O W ^a  

^a Neurologische Klinik   (Germany)

^b HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

Epilepsy; Hypometabolism; Penicillin; Posterior nucleus; Thalamic lesion

Indexed keywords

PENICILLIN G SODIUM;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; BRAIN METABOLISM; EPILEPSY; EPILEPTIC FOCUS; GLUCOSE BRAIN LEVEL; HISTOPATHOLOGY; MALE; NONHUMAN; PRIORITY JOURNAL; RADIOFREQUENCY; RAT; SOMATOSENSORY CORTEX; THALAMOCORTICAL TRACT;

ACUTE DISEASE; ANIMALS; BRAIN MAPPING; ELECTROENCEPHALOGRAPHY; EPILEPSIES, PARTIAL; GLUCOSE; MALE; MOTOR CORTEX; NEURAL PATHWAYS; RATS; RATS, WISTAR; SOMATOSENSORY CORTEX; THALAMUS;

EID: 0031796299     PISSN: 09201211     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0920-1211(98)00066-7     Document Type: Article

References (37)

1. Ackermann R.F., Engel J. Jr., Baxter L. Positron emission tomography and autoradiographic studies of glucose utilization following electroconvulsive seizures in humans and rats. Ann. New York Acad. Sci. 462:1986;263-269.
2. Ackermann R.F., Finch D.M., Babb T.L., Engel J. Increased glucose metabolism during long-duration recurrent inhibition of hippocampal pyramidal cells. J. Neurosci. 4:1984;251-264.
3. Bruehl C., Kloiber O., Hossmann K.A., Dorn T., Witte O.W. Regional hypometabolism in an acute model of focal epileptic activity in the rat. Eur. J. Neurosci. 7:1995;192-197.
4. Bruehl C., Witte O.W. Cellular activity underlying altered brain metabolism during focal epileptic activity. Ann. Neurol. 38:1995;414-420.
5. Chapin J.K., Lin C.S. The somatic sensory cortex of the rat. Kolb B., Tess R.C. The Cerebral Cortex of the Rat. 1990;341-380 MIT, Cambridge, MA.
6. Chapin J.K., Woodward D.J. Modulation of sensory responsiveness of single somatosensory cortical cells during movement and arousal behaviors. Exp. Neurol. 72:1981;164-178.
7. Collins R.C., Kennedy C., Sokoloff L., Plum F. Metabolic anatomy of focal motor seizures. Arch. Neurol. 33:1976;536-542.
8. Dorn T., Witte O.W. Separation of different interictal discharge patterns in acute experimentally induced epileptic foci of the rat in vivo. Brain Res. 616:1993;303-306.
9. Duncan R., Patterson J., Hadley D.M., Macpherson P., Brodie M.J., Bone I., MacGeorge A.P., Wyper D.J. CT, MR and SPECT imaging in temporal lobe epilepsy. J. Neurol. Neurosurg. Psychatr. 53:1990;11-15.
10. 14C]deoxyglucose metabolism. Mol. Brain Res. 46:1997;177-184.
11. Goldensohn E.S., Salazar A.M. Temporal and spatial distribution of intracellular potentials during generation and spread of epileptogenic discharges. Chauvel P., Delgado-Escueta A.V., Halgren E., Bancaud J. Advances of Neurology. 1986;559-582 Raven, New York.
12. Hagemann, G., Bruehl, C., Lutzenburg, M., Witte, O.W., 1998. Brain hypometabolism in chronic focal epilepsy induced by tetanus toxin in rat neocortex. Epilepsia, (in press).
13. Henry T.R., Sutherling W.W., Engel J. Jr., Risiner M.W., Levesque M.F., Mazziotta J.C., Phelps M.E. Interictal cerebral metabolism in partial epilepsies of neocortical origin. Epilepsy Res. 10:1991;174-182.
14. Herkenham M. Laminar organization of thalamic projections to the rat neocortex. Science. 207:1980;532-535.
15. Herkenham M. New perspectives on the organization and evolution of nonspecific thalamocortical projections. Jones E.G., Peters A. Cerebral Cortex. 1986;403-445 Plenum, New York.
16. Jokeit H., Seitz R.J., Markowitsch H.J., Neumann N., Witte O.W., Ebner A. Prefrontal asymmetric interictal glucose hypometabolism and cognitive impairment in patients with temporal lobe epilepsy. Brain. 120:1997;2283-2294.
17. Keller A. Intrinsic synaptic organization of the motor cortex. Cereb. Cortex. 3:1993;430-441.
18. Killackey H.P. Anatomical evidence for cortical subdivisions based on vertically discrete thalamic projections from the ventral posterior nucleus to cortical barrels in the rat. Brain Res. 51:1973;326-331.
19. Lin C.S., Chapin J.K. Some connections of SI and SII in the rat. Soc. Neurosci. Abstr. 7:1981;254-254.
20. Lu S.M., Lin C.S. Cortical projection patterns of the medial division of the mucleus posterior thalamus in the rat. Soc. Neurosci. Abstr. 12:1986;1434-1434.
21. Matsumoto H., Ajmone-Marsan C. Cortical cellular phenomena in experimental epilepsy: ictal manifestations. Exp. Neurol. 9:1964;305-326.
22. Matsumoto H., Ajmone-Marsan C. Cortical cellular phenomena in experimental epilepsy: interictal manifestations. Exp. Neurol. 9:1964;286-304.
23. Mies G., Cruz N., Sokoloff L. Comparison of freeze-blowing and funnel-freezing of rat brain for the measurement of cerebral glucose concentration in vivo. J. Neurochem. 56:1991;1673-1676.
24. Morrell F. Secondary epileptogenesis in man. Arch.Neurol. 42:1985;318-335.
25. Paxinos G., Watson C. The Rat Brain in Stereotaxic Coordinates. 1996;Academic Press, London.
26. Prince D.A., Wilder B.J. Control mechanisms in cortical epileptogenic foci: surround inhibition. Arch. Neurol. 16:1967;194-202.
27. Redecker C., Bruehl C., Hagemann G., Binus O., Witte O.W. Coupling of cortical and thalamic metabolism in experimentally induced visual somatosensory and focal epilepsy. Epilepsy Res. 27:1997;127-137.
28. Schlaug G., Antke C., Holthausen H., Arnold S., Ebner A., Tuxhorn I., Jancke L., Luders H., Witte O.W., Seitz R.J. Ictal motor signs and interictal regional cerebral hypometabolism. Neurology. 49:1997;341-350.
29. Siesjö B.K. Brain Energy Metabolism. 1978;Wiley, New York.
30. 14C)deoxyglucose method for the measurement of local cerebral glucose utilization: theory, procedure, and normal values in the conscious and anesthetized albino rat. J. Neurochem. 28:1977;897-916.
31. Speckmann E.J., Elger C. Penicillin induced epileptic foci in the motor cortex: vertical inhibition. Electroencephalogr. Clin. Neurophysiol. 56:1983;604-622.
32. Theodore W.H., Katz D., Kufta C., Sato S., Patronas N., Smother P., Bromfield E. Pathology of temporal lobe foci: correlation with CT, MRI, and PET. Neurology. 40:1990;797-803.
33. Theodore W.H., Sato S., Kufta C. Temporal lobectomy for uncontrolled seizures: the role of positron emission tomography. Ann. Neurol. 32:1992;789-794.
34. Witte O.W. Calcium ion involvement in epileptogenesis. Am. J. EEG Technol. 27:1987;223-238.
35. Witte, O.W., Bruehl, C., 1998. Remote functional disturbances in focal epilepsy. Advances in Neurology, (in press).
36. Witte O.W., Bruehl C., Schlaug S., Tuxhorn I., Lahl R., Villagran R., Seitz R.J. Dynamic changes of focal hypometabolism in relation to epileptic activity. J. Neurol. Sci. 124:1994;188-197.
37. Witte O.W., Uhlig S., Valle E. Separation of different types of afterpotentials following penicillin-induced paroxysmal depolarization shifts of neurons in the motor cortex of the rat. Neurosci. Lett. 101:1989;51-56.