-
1
-
-
0013572987
-
Toxicology and carcinogenesis studies of hydroquinone in F344/N rats and B6C3F1 mice (gavage studies)
-
U.S. Department of Health and Human Services, U.S. Public Health Service, National Institutes of Health
-
Kari F W (1989) Toxicology and carcinogenesis studies of hydroquinone in F344/N rats and B6C3F1 mice (gavage studies). National Toxicology Program Technical Report, p 366, U.S. Department of Health and Human Services, U.S. Public Health Service, National Institutes of Health.
-
(1989)
National Toxicology Program Technical Report
, pp. 366
-
-
Kari, F.W.1
-
3
-
-
0025948338
-
Induction of renal cell tumors in rats and mice, and enhancement of hepatocellular tumor development in mice after long-term hydroquinone treatment
-
Shibata, M.-A., Hirose, M., Tanaka, H., Asakawa, E., Shirai, T., and Ito, N. (1991) Induction of renal cell tumors in rats and mice, and enhancement of hepatocellular tumor development in mice after long-term hydroquinone treatment. Jpn. J. Cancer Res. 82, 1211-1219.
-
(1991)
Jpn. J. Cancer Res.
, vol.82
, pp. 1211-1219
-
-
Shibata, M.-A.1
Hirose, M.2
Tanaka, H.3
Asakawa, E.4
Shirai, T.5
Ito, N.6
-
4
-
-
0024237151
-
Sequential oxidation and glutathione addition to 1,4-benzoquinone: Correlation of toxicity with increased glutathione substitution
-
Lau, S. S., Hill, B. A., Highet, R. J., and Monks, T. J. (1988) Sequential oxidation and glutathione addition to 1,4-benzoquinone: correlation of toxicity with increased glutathione substitution. Mol. Pharmacol. 34, 829-836.
-
(1988)
Mol. Pharmacol.
, vol.34
, pp. 829-836
-
-
Lau, S.S.1
Hill, B.A.2
Highet, R.J.3
Monks, T.J.4
-
5
-
-
0031427713
-
Cytotoxicity and cell-proliferation induced by the nephrocarcinogen hydroquinone and its nephrotoxic metabolite 2,3,5-tris(glutathion-S-yl)hydroquinone
-
Peters, M. C. G., Jones, T. W., Monks, T. J., and Lau, S. S. (1997) Cytotoxicity and cell-proliferation induced by the nephrocarcinogen hydroquinone and its nephrotoxic metabolite 2,3,5-tris(glutathion-S-yl)hydroquinone. Carcinogenesis 18, 2393-2401.
-
(1997)
Carcinogenesis
, vol.18
, pp. 2393-2401
-
-
Peters, M.C.G.1
Jones, T.W.2
Monks, T.J.3
Lau, S.S.4
-
6
-
-
0027297075
-
Identification of multi-S-substituted conjugates of hydroquinone by HPLC-coulometric electrode array analysis and mass spectroscopy
-
Hill, B. A., Kleiner, H. E., Ryan, E. A., Dulik, D. M., Monks, T. J., and Lau, S. S. (1993) Identification of multi-S-substituted conjugates of hydroquinone by HPLC-coulometric electrode array analysis and mass spectroscopy. Chem. Res. Toxicol. 6, 459-469.
-
(1993)
Chem. Res. Toxicol.
, vol.6
, pp. 459-469
-
-
Hill, B.A.1
Kleiner, H.E.2
Ryan, E.A.3
Dulik, D.M.4
Monks, T.J.5
Lau, S.S.6
-
7
-
-
0028822165
-
Metabolism as a determinant of species susceptibility to 2,3,5-(triglutathion-Syl)hdroquinone-mediated nephrotoxicity. the role of N-acetylation and N-deacetylation
-
Lau, S. S., Kleiner, H. E., and Monks, T. J. (1995) Metabolism as a determinant of species susceptibility to 2,3,5-(triglutathion-Syl)hdroquinone-mediated nephrotoxicity. The role of N-acetylation and N-deacetylation. Drug Metab. Dispos. 23, 1136-1142.
-
(1995)
Drug Metab. Dispos.
, vol.23
, pp. 1136-1142
-
-
Lau, S.S.1
Kleiner, H.E.2
Monks, T.J.3
-
8
-
-
0021816377
-
Immunological studies on the mechanism of halothane-induced hepatotoxicity: Immunohistochemical evidence of trifluoroacetylated hepatocytes
-
Satoh, H., Fukuda, Y., Anderson, D. K., Ferrans, V. J., Gillette, J. R., and Pohl, L. R. (1985) Immunological studies on the mechanism of halothane-induced hepatotoxicity: immunohistochemical evidence of trifluoroacetylated hepatocytes. J. Pharmacol. Exp. Ther. 233, 857-862.
-
(1985)
J. Pharmacol. Exp. Ther.
, vol.233
, pp. 857-862
-
-
Satoh, H.1
Fukuda, Y.2
Anderson, D.K.3
Ferrans, V.J.4
Gillette, J.R.5
Pohl, L.R.6
-
9
-
-
0027276024
-
Metabolic activation of halothane to neoantigens in C57B1/10 mice: Immunochemical studies
-
Heijink, E., De Matteis, F., Gibbs, A. H., Davies, A., and White, I. N. H. (1993) Metabolic activation of halothane to neoantigens in C57B1/10 mice: immunochemical studies. Ear. J. Pharmacol. 248, 15-25.
-
(1993)
Ear. J. Pharmacol.
, vol.248
, pp. 15-25
-
-
Heijink, E.1
De Matteis, F.2
Gibbs, A.H.3
Davies, A.4
White, I.N.H.5
-
10
-
-
77957179482
-
Immunohistochemical localization of acetaminophen-bound liver proteins
-
Bartolone, J. B., Cohen, S. D., and Khairallah, E. A. (1989) Immunohistochemical localization of acetaminophen-bound liver proteins. Fundam. AppL Toxicol. 13, 859-862.
-
(1989)
Fundam. AppL Toxicol.
, vol.13
, pp. 859-862
-
-
Bartolone, J.B.1
Cohen, S.D.2
Khairallah, E.A.3
-
11
-
-
0345596419
-
Immunochemical comparison of 3'-hydroxyacetanilide and acetaminopehn binding in mouse liver
-
Salminen, W. F., Jr., Roberts, S. M., Pumford, N. R., and Hinson, J. A. (1998) Immunochemical comparison of 3'-hydroxyacetanilide and acetaminopehn binding in mouse liver. Drug. Metab. Dispos. 26, 267-271.
-
(1998)
Drug. Metab. Dispos.
, vol.26
, pp. 267-271
-
-
Salminen Jr., W.F.1
Roberts, S.M.2
Pumford, N.R.3
Hinson, J.A.4
-
12
-
-
0026094269
-
Detection of cysteine conjugate metabolite adduct formation with specific mitochondrial proteins using antibodies raised against halothane metabolite adducts
-
Hayden, P. J., Ichimura, T., McCann, D. J., Pohl, L. R., and Stevens, J. L. (1991) Detection of cysteine conjugate metabolite adduct formation with specific mitochondrial proteins using antibodies raised against halothane metabolite adducts. J. Biol. Chem. 266, 18415-18418.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 18415-18418
-
-
Hayden, P.J.1
Ichimura, T.2
McCann, D.J.3
Pohl, L.R.4
Stevens, J.L.5
-
13
-
-
0031741895
-
Immunochemical detection of quinol-thioether derived protein adducts
-
Kleiner, H. E., Rivera, M. I., Pumford, N. R., Monks, T. J., and Lau, S. S. (1998) Immunochemical detection of quinol-thioether derived protein adducts. Chem. Res. Toxicol. 11, 1283-1290.
-
(1998)
Chem. Res. Toxicol.
, vol.11
, pp. 1283-1290
-
-
Kleiner, H.E.1
Rivera, M.I.2
Pumford, N.R.3
Monks, T.J.4
Lau, S.S.5
-
14
-
-
71849104860
-
Protein measurement with the Folin phenol reagent
-
Lowry, O. H., Rosebrough, N. J., Farr, A. L., and Randall, R. J. (1951) Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193, 265-275.
-
(1951)
J. Biol. Chem.
, vol.193
, pp. 265-275
-
-
Lowry, O.H.1
Rosebrough, N.J.2
Farr, A.L.3
Randall, R.J.4
-
15
-
-
0014949207
-
Cleavage of structural proteins during the assembly of the head of bacteriophage T4
-
Laemmli, U. K. (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680-685.
-
(1970)
Nature
, vol.227
, pp. 680-685
-
-
Laemmli, U.K.1
-
16
-
-
0009482260
-
Electrophoretic transfer of protein from polyacrylamide gels to nitrocellulose sheets. Procedure and some applications
-
Towbin, H., Staehelin, T., and Gordon, J. (1979) Electrophoretic transfer of protein from polyacrylamide gels to nitrocellulose sheets. Procedure and some applications. Proc. Natl. Acad. Sci. U.S.A. 76, 4350-4354.
-
(1979)
Proc. Natl. Acad. Sci. U.S.A.
, vol.76
, pp. 4350-4354
-
-
Towbin, H.1
Staehelin, T.2
Gordon, J.3
-
17
-
-
0023253196
-
Identification by immunoblotting of three halothane-induced liver microsomal polypeptide antigens recognized by antibodies in sera from patients with halothane-associated hepatitis
-
Kenna, J. G., Neuberger, J., and Williams, R. (1987) Identification by immunoblotting of three halothane-induced liver microsomal polypeptide antigens recognized by antibodies in sera from patients with halothane-associated hepatitis. J. Pharmacol. Exp. Ther. 242, 733-740.
-
(1987)
J. Pharmacol. Exp. Ther.
, vol.242
, pp. 733-740
-
-
Kenna, J.G.1
Neuberger, J.2
Williams, R.3
-
18
-
-
0029054440
-
In vivo binding of diethyIstubestrol to nuclear proteins of kidneys of Syrian hamsters
-
Roy, D., Pathak, D. N., and Palangat, M.L (1995) In vivo binding of diethyIstubestrol to nuclear proteins of kidneys of Syrian hamsters. Cancer Lett. 90, 215-224.
-
(1995)
Cancer Lett.
, vol.90
, pp. 215-224
-
-
Roy, D.1
Pathak, D.N.2
Palangat, M.L.3
-
19
-
-
0027948538
-
Early morphological and biochemical changes during 2-bromo(diglutathion-S-yl)hydroquinone-induced nephrotoxicity
-
Rivera, M. I., Jones, T. W., Lau, S. S., and Monks, T. J. (1994) Early morphological and biochemical changes during 2-bromo(diglutathion-S-yl)hydroquinone-induced nephrotoxicity. Toxicol. Appl. Pharmacol. 128, 239-250.
-
(1994)
Toxicol. Appl. Pharmacol.
, vol.128
, pp. 239-250
-
-
Rivera, M.I.1
Jones, T.W.2
Lau, S.S.3
Monks, T.J.4
-
20
-
-
0027093458
-
The effects of 2,3,5(triglutathion-S-yl)hydroquinone on renal mitochondrial respiratory function in vivo and in vitro: Possible role in cytotoxicity
-
Hill, B. A., Monks, T. J., and Lau S. S. (1992) The effects of 2,3,5(triglutathion-S-yl)hydroquinone on renal mitochondrial respiratory function in vivo and in vitro: possible role in cytotoxicity. Toxicol. Appl. Pharmacol. 117, 165-171.
-
(1992)
Toxicol. Appl. Pharmacol.
, vol.117
, pp. 165-171
-
-
Hill, B.A.1
Monks, T.J.2
Lau, S.S.3
-
21
-
-
0029046826
-
Reactive oxygen species and DNA damage in 2-bromo(glutathion-S-yl)hydroquinone-mediated cytotoxicity
-
Mertens, J. J. W. M., Gibson, N. W., Lau, S. S., and Monks, T. J. (1995) Reactive oxygen species and DNA damage in 2-bromo(glutathion-S-yl)hydroquinone-mediated cytotoxicity. Arch. Biochem. Biophys. 320, 51-58.
-
(1995)
Arch. Biochem. Biophys.
, vol.320
, pp. 51-58
-
-
Mertens, J.J.W.M.1
Gibson, N.W.2
Lau, S.S.3
Monks, T.J.4
-
22
-
-
0029807279
-
Quinone-thioether-mediated DNA damage, growth arrest, and gadd153 expression in renal proximal tubular epithelial cells
-
Jeong, J. K., Stevens, J. L., Lau, S. S., and Monks, T. J. (1996) Quinone-thioether-mediated DNA damage, growth arrest, and gadd153 expression in renal proximal tubular epithelial cells. Mol. Pharmacol. 50, 592-598.
-
(1996)
Mol. Pharmacol.
, vol.50
, pp. 592-598
-
-
Jeong, J.K.1
Stevens, J.L.2
Lau, S.S.3
Monks, T.J.4
-
23
-
-
17944404402
-
DNA damage, gadd153 expression, and cytotoxicity in plateau-phase renal proximal tubular epithelial cells treated with a quinol-thioether
-
Jeong, J. J., Dybing, E., Søderlund, E., Brunborg, G., Holme, J. A., Lau, S. S., and Monks, T. J. (1997) DNA damage, gadd153 expression, and cytotoxicity in plateau-phase renal proximal tubular epithelial cells treated with a quinol-thioether. Arch. Biochem. Biophys. 341, 300-308.
-
(1997)
Arch. Biochem. Biophys.
, vol.341
, pp. 300-308
-
-
Jeong, J.J.1
Dybing, E.2
Søderlund, E.3
Brunborg, G.4
Holme, J.A.5
Lau, S.S.6
Monks, T.J.7
-
24
-
-
0030986142
-
The response of renal tubular epithelial cells to physiologically and chemically induced growth arrest
-
Jeong, J. K., Huang, Q., Lau, S. S., and Monks, T. J. (1997) The response of renal tubular epithelial cells to physiologically and chemically induced growth arrest. J. Biol. Chem. 272, 7511-7518.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 7511-7518
-
-
Jeong, J.K.1
Huang, Q.2
Lau, S.S.3
Monks, T.J.4
-
25
-
-
74049141143
-
Stress gene and growth related gene expression following acute renal injury
-
abstract
-
Peters, M. M. C. G., Monks, T. J., and Lau, S. S. (1996) Stress gene and growth related gene expression following acute renal injury. Fundam. Appl. Toxicol. 30, 331 (abstract).
-
(1996)
Fundam. Appl. Toxicol.
, vol.30
, pp. 331
-
-
Peters, M.M.C.G.1
Monks, T.J.2
Lau, S.S.3
-
26
-
-
0025938304
-
The role of γ-glutamyltranspeptidase in hydroquinone-glutathione conjugate mediated nephrotoxicity
-
Hill, B. A., Lo, H.-H., Monks, T. J., and Lau, S. S. (1991) The role of γ-glutamyltranspeptidase in hydroquinone-glutathione conjugate mediated nephrotoxicity. Adv. Exp. Med. Biol. 283, 749-751.
-
(1991)
Adv. Exp. Med. Biol.
, vol.283
, pp. 749-751
-
-
Hill, B.A.1
Lo, H.-H.2
Monks, T.J.3
Lau, S.S.4
-
27
-
-
0031446380
-
Biological reactivity of polyphenolic-glutathione conjugates
-
Monks, T. J., and Lau, S. S. (1997) Biological reactivity of polyphenolic-glutathione conjugates. Chem. Res. Toxicol. 10, 1296-1313.
-
(1997)
Chem. Res. Toxicol.
, vol.10
, pp. 1296-1313
-
-
Monks, T.J.1
Lau, S.S.2
-
28
-
-
0031777186
-
The pharmacology and toxicology of polyphenolic-glutathione conjugates
-
Monks, T. J., and Lau, S. S. (1998) The pharmacology and toxicology of polyphenolic-glutathione conjugates. Annu. Rev. Pharmacol. Toxicol. 38, 229-255.
-
(1998)
Annu. Rev. Pharmacol. Toxicol.
, vol.38
, pp. 229-255
-
-
Monks, T.J.1
Lau, S.S.2
-
29
-
-
0029952619
-
Further insights into the influence of L-cysteine on the oxidation chemistry of dopamine: Reaction pathways of potential relevance to Parkinson's disease
-
Shen, X. M., and Dryhurst, G. (1996) Further insights into the influence of L-cysteine on the oxidation chemistry of dopamine: reaction pathways of potential relevance to Parkinson's disease. Chem. Res. Toxicol. 9, 751-763.
-
(1996)
Chem. Res. Toxicol.
, vol.9
, pp. 751-763
-
-
Shen, X.M.1
Dryhurst, G.2
-
30
-
-
0029967920
-
Synthesis, redox properties, in vivo formation, and neurobehavioral effects of N-acetylcysteinyl conjugates of dopamine: Possible metabolites of relevance to Parkinson's disease
-
Shen, X. M., Xia, B., Wrona, M. Z., and Dryhurst, G. (1996) Synthesis, redox properties, in vivo formation, and neurobehavioral effects of N-acetylcysteinyl conjugates of dopamine: possible metabolites of relevance to Parkinson's disease. Chem. Res. Toxicol. 9, 1117-1126.
-
(1996)
Chem. Res. Toxicol.
, vol.9
, pp. 1117-1126
-
-
Shen, X.M.1
Xia, B.2
Wrona, M.Z.3
Dryhurst, G.4
-
31
-
-
0030886119
-
Irreversible inhibition of mitochondrial complex I by 7-(2-aminoethyl)-3,4-dihydro-5-hydroxy2H-l,4-benzothiazine-3-carboxylic acid (DHBT-1): A putative nigral endotoxin of relevance to Parkinson's disease
-
Li, H., and Dryhurst, G. (1997) Irreversible inhibition of mitochondrial complex I by 7-(2-aminoethyl)-3,4-dihydro-5-hydroxy2H-l,4-benzothiazine-3-carboxylic acid (DHBT-1): a putative nigral endotoxin of relevance to Parkinson's disease. J. Neurochem. 69, 1530-1541.
-
(1997)
J. Neurochem.
, vol.69
, pp. 1530-1541
-
-
Li, H.1
Dryhurst, G.2
-
32
-
-
0029886373
-
Influence of glutathione on the oxidation of l-methyl-6-hydroxy-l,2,3,4-tetrahydro-/3-carboline: Chemistry of potential relevance to the addictive and neurodegenerative consequences of ethanol use
-
Han, Q. P., and Dryhurst, G. (1996) Influence of glutathione on the oxidation of l-methyl-6-hydroxy-l,2,3,4-tetrahydro-/3-carboline: chemistry of potential relevance to the addictive and neurodegenerative consequences of ethanol use. J. Med. Chem. 39, 1494-1508.
-
(1996)
J. Med. Chem.
, vol.39
, pp. 1494-1508
-
-
Han, Q.P.1
Dryhurst, G.2
-
33
-
-
0030958542
-
Putative oxidative metabolites of 1-methyl-6-hydroxy-l,2,3,4-tetrahydro-β-carboline of potential relevance to the addictive and neurodegenerative consequences of ethanol abuse
-
Wrona, M. Z., Waskiewicz, J., Han, Q. P., Han, J., Li, H., and Dryhurst, G. (1997) Putative oxidative metabolites of 1-methyl-6-hydroxy-l,2,3,4-tetrahydro-β-carboline of potential relevance to the addictive and neurodegenerative consequences of ethanol abuse. Alcohol 14, 213-223.
-
(1997)
Alcohol
, vol.14
, pp. 213-223
-
-
Wrona, M.Z.1
Waskiewicz, J.2
Han, Q.P.3
Han, J.4
Li, H.5
Dryhurst, G.6
-
34
-
-
0030021812
-
Glutathione conjugates of tert-butyl hydroquinone, a metabolite of the urinary tract tumor promoter 3-tertbutylhydroxyanisole, are toxic to kidney and bladder
-
Peters, M. M. C. G., Rivera, M. I., Jones, T. W., Monks, T. J., and Lau, S. S. (1996) Glutathione conjugates of tert-butyl hydroquinone, a metabolite of the urinary tract tumor promoter 3-tertbutylhydroxyanisole, are toxic to kidney and bladder. Cancer Res. 56, 1006-1011.
-
(1996)
Cancer Res.
, vol.56
, pp. 1006-1011
-
-
Peters, M.M.C.G.1
Rivera, M.I.2
Jones, T.W.3
Monks, T.J.4
Lau, S.S.5
-
35
-
-
0031820170
-
2-Hydroxy4-glutathion-S-yl-17β-estradiol and 2-hydroxy-1-glutathion-S-yl-17β-estradiol produce oxidative stress and renal toxicity in an animal model of β-estradiol-mediated nephrocarcinogenicity
-
Butterworth, M., Lau, S. S., and Monks, T. J. (1998) 2-Hydroxy4-glutathion-S-yl-17β-estradiol and 2-hydroxy-1-glutathion-S-yl-17β-estradiol produce oxidative stress and renal toxicity in an animal model of β-estradiol-mediated nephrocarcinogenicity. Carcinogenesis 19, 133-139.
-
(1998)
Carcinogenesis
, vol.19
, pp. 133-139
-
-
Butterworth, M.1
Lau, S.S.2
Monks, T.J.3
-
36
-
-
0342304965
-
A nephrotoxic metabolite of hydroquinone induces renal cell tumorigenesis in Eker rats
-
abstract
-
Lau, S. S., Monks, T. J., Everitt, J. I., and Walker, C. L. (1998) A nephrotoxic metabolite of hydroquinone induces renal cell tumorigenesis in Eker rats. Toxicol. Sci. 42, 317 (abstract).
-
(1998)
Toxicol. Sci.
, vol.42
, pp. 317
-
-
Lau, S.S.1
Monks, T.J.2
Everitt, J.I.3
Walker, C.L.4
|