Human platelet activation is inhibited upstream of the activation of phospholipase A2 by U73343

Biochemical Pharmacology

Volumn 53, Issue 9, 1997, Pages 1257-1262

  Heemskerk, Johan W M ^a   Feijge, Marion A H ^a   Sage, Stewart O ^b,c   Farndale, Richard W ^b  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c PHYSIOLOGICAL LABORATORY   (United Kingdom)

Author keywords

Cytosolic calcium concentration; Phospholipase A2; Platelet; Tyrosine phosphorylation; U73122; U73343

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; 1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 2,5 PYRROLIDINEDIONE; PHOSPHOLIPASE A2;

ARTICLE; DRUG EFFECT; DRUG POTENCY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; NEGATIVE FEEDBACK; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION INHIBITION;

BLOOD PLATELETS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; ENZYME INHIBITORS; ESTRENES; HUMANS; PHOSPHOLIPASES A; PLATELET AGGREGATION INHIBITORS; PROTEIN-TYROSINE KINASES; PYRROLIDINONES; THAPSIGARGIN; THROMBIN;

EID: 0030848312     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(96)00888-X     Document Type: Article

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