Basal cells are progenitors of luminal cells in primary cultures of differentiating human prostatic epithelium

Prostate

Volumn 37, Issue 3, 1998, Pages 149-160

  Robinson, Emma J ^a   Neal, David E ^b   Collins, Anne T ^b  

^a Smith and Nephew Research Centre   (United Kingdom)

^b NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

Cytokeratin; Lineage; Stem cell

Indexed keywords

CYTOKERATIN; PROSTATE SPECIFIC ANTIGEN;

ARTICLE; BASAL CELL; CELL COMPARTMENTALIZATION; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SUBPOPULATION; EPITHELIUM CELL; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; NEUROSECRETORY CELL; PRIORITY JOURNAL; PROSTATE EPITHELIUM; PROTEIN EXPRESSION; STEM CELL;

CELL DIFFERENTIATION; CELL SEPARATION; CELLS, CULTURED; EPITHELIAL CELLS; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; HUMANS; KERATINS; KI-67 ANTIGEN; MALE; MICROSCOPY, CONFOCAL; MICROSCOPY, ELECTRON; PROSTATE; PROSTATE-SPECIFIC ANTIGEN; RECEPTORS, ANDROGEN; STEM CELLS;

EID: 0031792660     PISSN: 02704137     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0045(19981101)37:3<149::AID-PROS4>3.0.CO;2-E     Document Type: Article

References (33)

1. Dermer G: Basal cell proliferation in benign prostatic hyperplasia. Cancer 1978;41:1857-1862.
2. Brawer MK, Peehl DM, Stamey TA, Bostwick DG: Keratin immunoreactivity in the benign and neoplastic human prostate. Cancer Res 1985;45:3663-3667.
3. Wernert N, Seitz G, Achtstätter T: Immunohistochemical investigation of different cytokeratins and vimentin in the prostate from the fetal period up to adulthood and in prostate carcinoma. Pathol Res Pract 1987;182:617-626.
4. Verhagen APM, Ramaekers FCS, Aalders TW, Schaafsma HE, Debruyne FMJ, Schalken JA: Colocalization of basal and luminal cell-type cytokeratins in human prostate cancer. Cancer Res 1992;52:6182-6187.
5. Brandes D: The fine structure and histochemistry of prostatic glands in relation to sex hormones. Int Rev Cytol 1966;20:207-276.
6. Bonkhoff H, Stein U, Remberger K: Multidirectional differentiation in the normal, hyperplastic, and neoplastic human prostate. Simultaneous demonstration of cell specific epithelial markers. Hum Pathol 1994;25:42-46.
7. Bonkhoff H, Remberger K: Differentiation pathways and histogenetic aspects of normal and abnormal prostatic growth - A stem cell model. Prostate 1996;28:98-106.
8. Moll R, Franke WW, Schiller DL: The catalogue of human cytokeratins: Patterns of expression in normal epithelia, tumors and cultured cells. Cell 1982;31:11-24.
9. Achtstätter T, Moll R, Moor B, Franke WW: Cytokeratin polypeptide patterns of different epithelia of the human male urogenital tract: Immunofluorescence and gel electrophoretic studies. J Histochem Cytochem 1985;33:415-426.
10. Verhagen APM, Aalders TW, Ramaekers FCS, Debruyne FMJ, Schalken JA: Differential expression of keratins in the basal and luminal compartments of rat prostatic epithelium during degeneration and regeneration. Prostate 1988;13:25-38.
11. Sherwood ER, Berg LA, Mitchell NJ, McNeal JE, Kozlowski JM, Lee C: Differential cytokeratin expression in normal hyperplastic and malignant epithelial cells from human prostate. J Urol 1990;143:167-171.
12. Okada H, Tsubura A, Okamura A, Senzaki H, Naka Y, Komatz Y, Morii S: Keratin profiles in normal/hyperplastic prostates and prostate carcinoma. Virchows Arch [A] 1992;42:157-161.
13. Cussenot O, Berthon P, Cochand-Priollet B, Maitland NJ, LeDuc A: Immunocytochemical comparison of cultured normal epithelial prostatic cells with prostatic tissue sections. Exp Cell Res 1994;214:83-92.
14. Heatfield B, Sanefuji H, Trump B: Studies on carcinogenesis of human prostate. IV. Comparison of normal and neoplastic prostate during long-term explant culture. Scanning Microsc 1979; 3:645-656.
15. Jones EG, Harper ME: Studies on the proliferation, secretory activities, and epidermal growth factor receptor expression in benign prostatic hyperplasia explant cultures. Prostate 1992;20: 133-149.
16. Peehl DM, Leung GK, Wong ST: Keratin expression: A measure of phenotypic modulation of human prostatic epithelial cells by growth inhibitory factors. Cell Tissue Res 1994;277:11-18.
17. Peehl DM, Wong ST, Rubin JS: KGF and EGF differentially regulate the phenotype of prostatic epithelial cells. Growth Regulat 1996;6:22-31.
18. Merchant DJ, Clarke SM, Ives K, Harris S: Primary explant culture: An in vitro model of the human prostate. Prostate 1983;4: 523-542.
19. Bonkhoff H, Stein U, Remberger K: The proliferative function of basal cells in the normal and hyperplastic human prostate. Prostate 1994;24:114-118.
20. Isaacs JT: Control of cell proliferation and cell death in the normal and neoplastic prostate: A stem cell model. In Rogers CH, Coffey DS, Cunha G, Grayhack JT, Hinman F Jr, Horton R (eds): "Benign Prostatic Hyperplasia," Report no. NIH 87-2881. Department of Health and Human Services, Bethesda, National Institutes of Health, 1987:85-94.
21. Evans GS, Chandler JA: Cell proliferation studies in the rat prostate: II. The effects of castration and androgen-induced regeneration upon basal and secretory cell proliferation. Prostate 1987;11:339-351.
22. English HF, Santen RJ, Isaacs JT: Response of glandular versus basal rat ventral prostatic epithelial cells to androgen withdrawal and replacement. Prostate 1987;11:229-242.
23. Cunha GR, Chung LKW, Shannon JM, Taguchi O, Fujii H: Hormone-induced morphogenesis and growth: Role of mesenchymal epithelial interactions. Recent Prog Horm Res 1983;33:559-598.
24. Tenniswood M: Role of epithelial-stromal interactions in the control of gene expression in the prostate: A hypothesis. Prostate 1986;9:375-345.
25. Gerdes J, Lemke H, Baisch H, Wacker HH, Schwab U, Stein H: Cell cycle analysis of a cell proliferation associated human nuclear antigen defined by a monoclonal antibody Ki-67. J Immunol 1984;83:1710-1715.
26. Collins AT, Robinson EJ, Neal DE: Benign prostatic stromal cells are regulated by basic fibroblast growth factor and transforming growth factor-β1. J Endocrinol 1996;151:315-322.
27. McKeehan WL, Adams PS, Rosser MP: Direct mitogenic effects of insulin, epidermal growth factor, glucocorticoid, cholera toxin, unknown pituitary factors and possibly prolactin, but not androgen, on normal rat prostate epithelial cells in serum-free, primary cell culture. Cancer Res 1984;44:1998-2010.
28. Kemppainen JA, Lane MV, Sar M, Wilson EM: Androgen receptor phosphorylation, turnover, nuclear transport, and transcriptional activation. Specificity for steroids and antihormones. J Biol Chem 1992;267:968-974.
29. Georget V, Lobaccaro JM, Terouanne B, Mangeat P, Nicolas JC, Sultan C: Trafficking of the androgen receptor in living cells with fused green fluorescent protein-androgen receptor. Mol Cell Endocrinol 1997;129:17-26.
30. Cunha GR, Donjacour AA, Cooke PS, Mee S, Bigsby RM, Higgins SJ, Sugimura Y: The endocrinology and developmental biology of the prostate. Endocr Rev 1987;8:338-362.
31. Cunha GR, Young P, Higgins SJ, Cooke PS: Neonatal seminal vesicle mesenchyme induces a new morphological and functional phenotype in the epithelia of adult ureter and ductus deferens. Development 1991;111:145-158.
32. Donjacour AA, Cunha GR: Induction of prostatic morphology and secretion in urothelium by seminal vesicle mesenchyme. Development 1995;121:2199-2207.
33. Sinha AA, Bentley MD: The relationship of epithelial cell types in the ventral prostate glands of castrated mice treated with testosterone. Anat Rec 1984;203:533-544.