Chromosome bands 3p14.2, 9p21, and 13q14 are frequently deleted in roentgenographically occult bronchogenic squamous cell carcinoma of the lung

Genes Chromosomes and Cancer

Volumn 23, Issue 4, 1998, Pages 367-370

  Sato, Masami ^a,b   Sakurada, Akira ^a,b   Sagawa, Motoyasu ^a   Endo, Chiaki ^a   Tanita, Tatsuo ^a   Kondo, Takashi ^a   Tsuchiya, Eiju ^c   Fujimura, Shigefumi ^a   Horii, Akira ^b  

^a TOHOKU UNIVERSITY   (Japan)

^b TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c SAITAMA CANCER CENTER   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; BRONCHUS CANCER; CHROMOSOME 13Q; CHROMOSOME 3P; CHROMOSOME 9P; CHROMOSOME DELETION; CONTROLLED STUDY; FEMALE; HETEROZYGOSITY LOSS; HUMAN; HUMAN TISSUE; LUNG CARCINOGENESIS; LUNG SQUAMOUS CELL CARCINOMA; MAJOR CLINICAL STUDY; MALE; OCCULT CANCER; PRIORITY JOURNAL; TUMOR SUPPRESSOR GENE;

AGED; CARCINOMA, BRONCHOGENIC; CARCINOMA, SQUAMOUS CELL; CHROMOSOME BANDING; CHROMOSOME DELETION; CHROMOSOMES, HUMAN; CHROMOSOMES, HUMAN, PAIR 13; CHROMOSOMES, HUMAN, PAIR 3; CHROMOSOMES, HUMAN, PAIR 9; FEMALE; HUMANS; LOSS OF HETEROZYGOSITY; LUNG NEOPLASMS; MALE; MIDDLE AGED; NEOPLASM STAGING; NEOPLASMS, UNKNOWN PRIMARY;

EID: 0031792403     PISSN: 10452257     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2264(199812)23:4<367::AID-GCC13>3.0.CO;2-W     Document Type: Article

References (14)

1. Endo C, Sagawa M, Sato M, Chen Y, Sakurada A, Aikawa H, Takahashi S, Usuda K, Saito Y, Fujimura S (1998) Sequential loss of heterozygosity in the progression of squamos cell carcinoma of the lung. Br J Cancer 78:612-615.
2. Hahn SA, Schutte M, Hoque AT, Moskaluk CA, da Costa LT, Rozenblum E, Weinstein CL, Fischer A, Yeo CJ, Hruban RH, Kern SE (1996) DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1. Science 271:350-353.
3. Hayashi N, Sugimoto Y, Tsuchiya E, Ogawa M, Nakamura Y (1994) Somatic mutation of the MTS (multiple tumor suppressor) 1/CDK41 (cyclin-dependent kinase 4 inhibitor) gene in human primary non-small cell lung carcinoma. Biochem Biophys Res Commun 15:1426-1430.
4. Kaghad M, Bonnet H, Yang A, Creancier L, Biscan JC, Valent A, Minty A, Chalon P, Lelias JM, Dumont X, Ferrara P, McKeon F, Caput D (1997) Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers. Cell 90:809-819.
5. Lee SW (1996) H-cadherin, a novel cadherin with growth inhibitory functions and diminished expression in human breast cancer. Nat Med 2:776-782.
6. Mitsudomi T, Steinberg SM, Nau M, Carbone D, D'Amico D, Bodner S, Oie HK, Linnoila RI, Mulshine JL, Minna JD, Gadzar AF (1992) p53 mutation in non small cell lung cancer cell lines and their correlation with the presence of RAS mutations and clinical features. Oncogene 7:171-180.
7. Mollenhauer J, Wiemann S, Scheurlen W, Korn B, Hayashi Y, Wilgenbus KK, von Deimling A, Poustka A (1997) DMBT1, a new member of the SRCR superfamily, on chromosome 10q25.3-26.1 is deleted in malignant brain tumours. Nat Genet 17:32-39.
8. Nagamoto N, Saito Y, Sato M, Sagawa M, Kanma K, Takahashi S, Usuda K, Endo C, Fujimura S, Nakada T, Ohukuda K (1993) Clinicopathological analysis of 19 cases of isolated carcinoma in situ of the bronchus. Am J Surg Pathol 17:1234-1243.
9. Ohta M, Inoue H, Cotticelli MG, Kastury K, Baffa R, Palazzo J, Siprashvili Z, Mori M, McCue P, Druck T, Croce CM, Huebner K (1996) The FHIT gene, spanning the chromosome 3p14.2 fragile site and renal carcinoma-associated t(3;8) breakpoint, is abnormal in digestive tract cancers. Cell 84:587-597.
10. Rodenhuis S, Slebos RJC (1992) Clinical significance of ras oncogene activation in human lung cancer. Cancer Res 52:2665-2669.
11. Saito Y, Nagamoto N, Ota S, Sato M, Sagawa M, Kanma K, Takahashi S, Usuda K, Endo C, Imai T, Fujimura S (1992) Results of surgical treatment to roentgenographically occult bronchogenic squamous cell carcinoma. J Thorac Cardiovasc Surg 104:401-407.
12. Sato M, Mori Y, Sakurada A, Fukushige S, Ishikawa Y, Tsuchiya E, Saito Y, Nukiwa T, Fujimura S, Horii A (1998a) Identification of a 910 kb region of common allelic loss in chromosome bands 16q24.1-q24.2 in human lung cancer. Genes Chromosomes Cancer 22:1-8.
13. Sato M, Saito Y, Usuda K, Takahashi S, Sagawa M, Fujimura S (1998b) Occult lung cancer beyond bronchoscopic visibility in sputum-cytology positive patients. Lung Cancer 20:17-24.
14. Takahashi T, Nau M, Chiba I, Birrer M, Rosenberg R, Vinocour M, Levitt M, Pass H, Gazdar A, Minna JD (1989) p53: A frequent target for genetic abnormalities in lung cancer. Science 246:491-494.