Differential tolerance to morphine's immunomodulatory effects following continuous administration

Drug and Alcohol Dependence

Volumn 53, Issue 1, 1998, Pages 31-38

  West, J Paige ^a   Dykstra, Linda A ^a   Lysle, Donald T ^a  

^a University of North Carolina at Chapel Hill   (United States)

Author keywords

Interferon; Con A; Continuous infusion; Morphine; Natural killer; Tolerance; TSST 1

Indexed keywords

CONCANAVALIN A; DRINKING WATER; GAMMA INTERFERON; MORPHINE; TOXIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BOLUS INJECTION; CELL PROLIFERATION; CONTINUOUS INFUSION; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOLOGICAL TOLERANCE; IMMUNOMODULATION; INTRAVENOUS DRUG ADMINISTRATION; MALE; NATURAL KILLER CELL; NONHUMAN; OSMOTIC MINIPUMP; PRIORITY JOURNAL; RAT; SUBCUTANEOUS DRUG ADMINISTRATION; T LYMPHOCYTE;

ANIMALS; DRUG TOLERANCE; IMMUNE TOLERANCE; INFUSION PUMPS, IMPLANTABLE; INJECTIONS, SUBCUTANEOUS; INTERFERON TYPE II; KILLER CELLS, NATURAL; LYMPHOCYTE ACTIVATION; MALE; MORPHINE; MORPHINE DEPENDENCE; RATS; RATS, INBRED LEW; SUBSTANCE ABUSE, INTRAVENOUS;

EID: 0031792010     PISSN: 03768716     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0376-8716(98)00109-4     Document Type: Article

References (38)

1. Ayesta, F.J., Florez, J., 1989. Tolerance to respiratory actions of sufentanil: functional tolerance and route-dependent differential tolerance. J. Pharmacol. Exp. Ther. 250, 371-378.
2. Bryant, H., Roudebush, R., 1990. Suppressive effects of morphine pellet implants on in vivo parameters of immune function. J. Pharmacol. Exp. Ther. 255, 410-414.
3. Bryant, H., Bernton, E., Holaday, J., 1988a. Morphine pellet-induced immunomodulation in mice: temporal relationships. J. Pharmacol. Exp. Ther. 245, 913-920.
4. Bryant, H., Yoburn, B., Inturrisi, C., Bernton, E., Holaday, J., 1988b. Morphine-induced immunomodulation is not related to serum morphine concentrations. Eur. J. Pharmacol. 149, 165-169.
5. Bussiere, J.L., Adler, M.W., Roger, T.J., Eisenstein, T.K., 1993. Cytokine reversal of morphine-induced suppression of the antibody response. J. Pharmacol. Exp. Ther. 264, 591-597.
6. Carr, D.J.J., France, C.P., 1993. Immune alterations in morphine-treated rhesus monkeys. J. Pharmacol. Exp. Ther. 267, 9-15.
7. Chao, C.C., Sharp, B.M., Pomeroy, C., Filice, G.A., Peterson, P.K., 1990. Lethality of morphine in mice infected with Toxoplasma gondii. J. Pharmacol. Exp. Ther. 252, 605-609.
8. DeJarlais, D., Freidman, S., Stoneburner, R., 1988. HIV infection and intravenous drug use: critical issues in transmission dynamics, infection outcomes, and prevention. Rev. Infect. Dis. 10, 151-158.
9. Donahoe, R.M., Byrd, L.D, McClure, H.M., Fultz, P., Brantley, M., Marsteller, F., Ansari, A.A., Wenzel, D., Aceto, M., 1993. Consequences of opiate-dependency in a monkey model of AIDS. In: Friedman, H., Klein, T.W., Specter, S. (Eds.), Drugs of Abuse, Immunity, and AIDS. Plenum Press, New York, pp. 21-28.
10. Eisenstein, T.K., Meissler, J.J. Jr., Geller, E.B., Adler, M.W., 1990. Immunosuppresion to tetanus toxoid induced by implanted morphine pellets. Ann. New York Acad. Sci. 594, 377-379.
11. Fecho, K., Maslonek, K.A., Dykstra, L.A., Lysle, D.T., 1996. Evidence for sympathetic and adrenal involvement in the immunomodulatory effects of acute morphine treatment in rats. J. Pharmacol. Exp. Ther. 277, 633-645.
12. Fernandes, M., Kluwe, S., Coper, H., 1977. Quantitative assessment of tolerance to and dependence on morphine in mice. NaunynSchmiederberg's Arch. Pharmacol. 297, 53-60.
13. Fernandes, M., Kluwe, S., Coper, H., 1982. Development and loss of tolerance to morphine in the rat. Psychopharmacology 78, 234-238.
14. Holmberg, S.D., 1996. The estimated prevalence and incidence of HIV in 96 large US metropolitan areas. Am. J. Public Health 86 (5), 642-651.
15. Hussey, H., Katz, S., 1950. Infections resulting from narcotic addiction: report of 102 cases. Am. J. Med. 9, 186-193.
16. Iwamoto, K., Klaassen, C., 1977. First pass effect of morphine in the rat. J. Pharmacol. Exp. Ther. 200, 236-244.
17. Kreek, M.J., 1996. Long-term pharmacotherapy for opiate (primarily heroin) addiction: Opioid agonists. In: Schuster, C.R., Kuhar, M.J. (Eds.), Pharmacological Aspects of Drug Dependence: Vol. 118. Toward an Integrated Neurobehavioral Approach. Springer, New York, pp. 487-562.
18. Lange, D.G., Fujimoto, J.M., Fuhrman-Lane, C.L., Wang, R.I.H., 1980. Unidirectional non-cross tolerance to etorphine in morphine-tolerance mice and the role of blood-brain-barrier. Toxicol. Appl. Pharmacol. 54, 177-186.
19. Ling, G.S.F., Paul, D., Simantov, R., Pasternak, G.W., 1989. Differential development of acute tolerance to analgesia, respiratory depression, gastrointestinal transit and hormone release in a morphine infusion model. Life Sci. 45, 1627-1636.
20. Louria, D.B., Hensle, T., Rose, J., 1967. The major medical complications of heroin addiction. Ann. Int. Med. 67, 1-22.
21. Lysle, D., Coussons, M., Watts, V., Bennett, E., Dykstra, L., 1993. Morphine-induced alterations of immune status: dose-dependent, compartment specificity, and antagonism by naltrexone. J. Pharmacol. Exp. Ther. 276, 626-636.
22. McMillan, D., Leander, J., Wilson, T., Wallace, S., Fix, T., Redding, S., Turk, R., 1976. Oral ingestion of narcotic analgesics by rats. J. Pharmacol. Exp. Ther. 192, 506-512.
23. Molitor, T.W., Morilla, A., Risdahl, J.M., Murtaugh, M.P., Chao, C.C., Peterson, P.K., 1992. Chronic morphine administration impairs cell mediated immune responses in swine. J. Pharmacol. Exp. Ther. 260, 581-586.
24. Nelson, C.J., Lysle, D.T., 1997. Surgical stress alters immune status: evidence for the role of catecholamines. Soc. Neurosci. Abstr. 23, 1510.
25. Nelson, C.J., Dykstra, L.A., Lysle, D.T., 1997. Comparison of the time course of morphine's analgesic and immunologic effects. Anest. Analg. 85, 620-626.
26. Novick, D.M., Ochshorn, M., Ghali, V., Croxson, T.S., Mercer, W.D., Chiorazzi, N., Kreek, M.J., 1989. Natural killer cell activity and lymphocyte subsets in parenteral heroin abusers and long term methadone maintenance patients. J. Pharmacol. Exp. Ther. 250, 606-610.
27. Pacifici, R., DiCarlo, S., Bacosi, A., Zuccaro, P., 1993. Macrophage functions in drugs of abuse-treated mice. Int. J. Immunopharmacol. 15, 711-716.
28. Pickens, R.W., Battjes, R., Svikis, D.S., Gupman, A.E., 1993. Substance use risk factors for HIV infection. Rec. Adv. Addict. Dis. 16 (1), 119-125.
29. Pross, H., Maroun, J., 1984. The standardization of NK cell assays for the use in studies of biological response modifiers. J. Immunol. Methods 68, 235-249.
30. Risdahl, J.M., Peterson, P.K., Chao, C.C., Pijoan, C., Molitor, T.W., 1993. Effects of morphine dependence on the pathogenesis of swine herpesvirus infection. J. Infect. Dis. 167, 1281-1287.
31. Shavit, Y., Terman, G., Lewis, J., Zane, C., Gale, R., Leibeskind, J., 1986. Effects of foot shock stress and morphine on natural killer cell lymphocytes in rats: studies of tolerance and cross tolerance. Brain Res. 372, 382-385.
32. Starec, M., Rouveix, B., Sinet, M., Chau, F., Desforges, B., Pocidalo, J., Lechat, P., 1991. Immune status and survival of opiate- and cocaine-treated mice infected with friend virus. J. Pharmacol. Exp. Ther. 259, 745-750.
33. Stephan, R.N., Saizawa, M., Conrad, P.J., Dean, R.E., Geha, A.S., Chaudry, I.H., 1987. Depressed antigen presentation function and membrane interleukin-1 activity of peritoneal macrophages after laparotomy. Surgery 102, 147-154.
34. Tubaro, E., Borelli, G., Croce, C., Cavallo, G., Santiangeli, C., 1983. Effect of morphine on resistance to infection. J. Infect. Dis. 148, 656-666.
35. Veyries, M., Sinet, M., Desforges, B., Rouveix, B., 1995. Effects of morphine on the pathogenesis of murine friend retrovirus infection. J. Pharmacol. Exp. Ther. 272, 498-504.
36. West, J.P., Lysle, D.T., Dykstra, L.A., 1997. Tolerance development to morphine-induced alterations of immune status. Drug Alcohol Depend. 46, 147-157.
37. West, J.P., Dykstra, L.A., Lysle, D.T., 1998. Time-dependent immunomodulatory effects following natural opioid withdrawal. NIDA Res. Monogr. 178, p. 201.
38. Zellweger, R., Ayala, A., Zhu, X., Morrison, M., Chaudry, I.H., 1995. Effect of surgical trauma on splenocyte and peritoneal macrophage immune function. J. Trauma: Inj. Infect. Crit. Care. 39, 645-650.