Tolerance development to morphine-induced alterations of immune status

Drug and Alcohol Dependence

Volumn 46, Issue 3, 1997, Pages 147-157

  West, J Paige ^a   Lysle, Donald T ^a   Dykstra, Linda A ^a  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

Antinociception; Immune; Morphine; Tolerance; Withdrawal

Indexed keywords

GAMMA INTERFERON; MORPHINE; MORPHINE SULFATE; NALTREXONE; TAP WATER;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTINOCICEPTION; ARTICLE; B LYMPHOCYTE; CONTROLLED STUDY; IMMUNE STATUS; LYMPHOCYTE PROLIFERATION; MALE; MORPHINE TOLERANCE; NARCOTIC DEPENDENCE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; RAT; T LYMPHOCYTE;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG TOLERANCE; IMMUNE TOLERANCE; INTERFERON TYPE II; KILLER CELLS, NATURAL; LYMPHOCYTE ACTIVATION; LYMPHOCYTE SUBSETS; MALE; MORPHINE; MORPHINE DEPENDENCE; PAIN THRESHOLD; RATS; RATS, INBRED LEW; SUBSTANCE WITHDRAWAL SYNDROME;

ANIMALIA;

EID: 0030803354     PISSN: 03768716     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0376-8716(97)00059-8     Document Type: Article

References (43)

1. Bayer, B., Daussin, S., Hernandez, M., Irvin, L., 1990. Morphine inhibition of lymphocyte activity is mediated by an opioid dependent mechanism. Neuropharmacology 29, 369-374.
2. Bayer, B., Gastonguay, M., Hernandez, M., 1992. Distinction between the in vitro and in vivo inhibitory effects of morphine on lymphocyte proliferation based on agonist sensitivity and naltrexone reversibility. Immunopharmacology 23, 117-124.
3. Bayer, B., Hernandez, M., Ding, X., 1996. Tolerance and crosstolerance to the suppressive effects of cocaine and morphine on lymphocyte proliferation. Pharmacol. Biochem. Behav. 53, 227-234.
4. Bryant, H., Roudebush, R., 1990. Suppressive effects of morphine pellet implants on in vivo parameters of immune function. J. Pharmacol. Exp. Ther. 255, 410-414.
5. Bryant, H., Bernton, E., Holaday, J., 1988a. Morphine pellet-induced immunomodulation in mice: Temporal relationships. J. Pharmacol. Exp. Ther. 245, 913-920.
6. Bryant, H., Yoburn, B., Inturrisi, C., Bernton, E., Holaday, J., 1988b. Morphine-induced immunomodulation is not related to serum morphine concentrations. Eur. J. Pharmacol. 149, 165-169.
7. Bussiere, J.L., Adler, M.W., Rogers, T.J., Eisenstein, T.K., 1993. Cytokine reversal of morphine-induced suppression of the antibody response. J. Pharmacol. Exp. Ther. 264, 591-597.
8. Cantacuzene, M., 1898. Nouvelles recherches sur le mode de destruction des vibrions dans l'organisme. Ann. Inst. Pastuer. 12, 273-300.
9. Caroleo, M.C., Arbitrio, M., Melchiorri, D., Nistico, G., 1994. A reappraisal of the role of the various opioid receptor subtypes in cell-mediated immunity. Neuroimmunomodulation 1, 141-147.
10. Carr, D.J.J., 1991. The role of endogenous opioids and their receptors in the immune system. Proc. Soc. Exp. Biol. Med. 198, 710-720.
11. Carr, D.J.J., France, C.P., 1993. Immune alterations in morphine-treated rhesus monkeys. J. Pharmacol. Exp. Ther. 267, 9-15.
12. DesJarlais, D., Freidman, S., Stoneburner, R., 1988. HIV infection and intravenous drug use: Critical issues in transmission dynamics, infection outcomes, and prevention. Rev. Infect. Dis. 10, 151-158.
13. Eisenstein, T., JJ Meissler, J., Geller, E., Adler, M., 1990. Immunosuppression to tetanus toxoid induced by implanted morphine pellets. Ann. NY Acad. Sci. 594, 377-379.
14. Fecho, K., Dykstra, L., Lysle, D., 1993a. Evidence for beta-adrenergic receptor involvement in the immunomodulatory effects of morphine. J. Pharmacol. Exp. Ther. 265, 1079-1087.
15. Fecho, K., Maslonek, K., Dykstra, L., Lysle, D., 1993b. Alterations of immune status induced by the sympathetic nervous system: Immunomodulatory effects of DMPP alone and in combination with morphine. Brain Behav. Immun. 7, 253-270.
16. Fecho, K., Maslonek, K., Dykstra, L., Lysle, D., 1996. Evidence for sympathetic and adrenal involvement in the immunomodulatory effects of acute morphine treatment in rats. J. Pharmacol. Exp. Ther. 277, 633-645.
17. Flores, L., Hernandez, M., Bayer, B., 1994. Acute immunosuppressive effects of morphine: lack of involvement of pituitary and adrenal factors. J. Pharmacol. Exp. Ther. 268, 1129-1134.
18. Gellert, V., Holtzman, S.G., 1978. Development and maintenance of morphine tolerance and dependence in the rat by scheduled access to morphine drinking solutions. J. Pharmacol. Exp. Ther. 205, 536-546.
19. Hernandez, M.C., Flores, L.B., Bayer, B.M., 1993. Immunosuppression by morphine is mediated by central pathways. J. Pharmacol. Exp. Ther. 267, 1336-1341.
20. Hussey, H., Katz, S., 1950. Infections resulting from narcotic addiction: report of 102 cases. Am. J. Med. 9, 186-193.
21. Lockwood, L., Silbert, L., Fleshner, M., Laudenslager, M., Watkins, L., Maier, S., 1994. Morphine-induced decreases in in vivo antibody responses. Brain Behav. Immun. 8, 24-36.
22. Louria, D.B., Hensle, T., Rose, J., 1967. The major medical complications of heroin addiction. Ann. Intern. Med. 67, 1-22.
23. Lysle, D., Coussons, M., Watts, V., Bennett, E., Dykstra, L., 1993. Morphine-induced alterations of immune status: Dose-dependency, compartment specificity, and antagonism by naltrexone. J. Pharmacol. Exp. Ther. 276, 626-636.
24. Lysle, D., Hoffman, K., Dykstra, L., 1996. Evidence for the involvement of the caudal region of the periaquaductal gray in a subset of morphine-induced alterations of immune status. J. Pharmacol. Exp. Ther. 277, 1533-1540.
25. McDonough, R., Madden, J., Falek, A., Shafer, D., Pline, M., Gordon, D., Bokos, P., Kuehnle, J., Mendelson, J., 1980. Alteration of T-and null lymphocyte frequencies in the peripheral blood of human opiate addicts: in vivo evidence for opiate receptor sites on T-lymphocytes. J. Immunol. 125, 23.
26. McLachlan, C., Crofts, N., Wodak, A., Crowe, S., 1993. The effects of methadone on immune function among injecting drug users: A review. Addiction 88, 257-263.
27. McMillan, D., Leander, J., Wilson, T., Wallace, S., Fix, T., Redding, S., Turk, R., 1976. Oral ingestion of narcotic analgesics by rats. J. Pharmacol. Exp. Ther. 192, 506-512.
28. Molitor, T.W., Morilla, A., Risdahl, J.M., Murtaugh, M.P., Chao, C.C., Peterson, P.K., 1992. Chronic morphine administration impairs cell mediated immune responses in swine. J. Pharmacol. Exp. Ther. 260, 581-586.
29. Novick, D.M., Ochshorn, M., Ghali, V., Croxson, T.S., Mercer, W.D., Chiorazzi, N., Kreek, M.J., 1989. Natural killer cell activity and lymphocyte subsets in parenteral heroin abusers and long term methadone maintenance patients. J. Pharmacol. Exp. Ther. 250, 606-610.
30. Pacifici, R., Carlo, S.D., Bacosi, A., Zuccaro, P., 1993. Macrophage functions in drugs of abuse treated mice. Int. J. Immunopharmacol. 15, 711-716.
31. Picker, M., Craft, R., Negus, S., Powell, K., Mattox, S., Jones, S., Hargrove, B., Dykstra, L., 1992. Intermediate efficacy mu opioids: Examination of their morphine-like stimulus effects and response rate-decreasing effects of morphine-tolerant rats. J. Pharmacol. Exp. Ther. 263, 668-681.
32. Picker, M., Negus, S., Craft, R., 1990. Butorphanol's efficacy at mu and kappa opioid receptors: Inferences based on the schedule-controlled behavior of nontolerant and morphine-tolerant rats and on the responding of rats under a drug discrimination procedure. Pharmacol. Biochem. Behav. 36, 563-568.
33. Pierce, T., Tiong, G., Olley, J., 1992. Morphine and methadone dependence in the rat: Withdrawal and brain met-enkephalin levels. Pharmacol. Biochem. Behav. 42, 91-96.
34. Pross, H., Maroun, J., 1984. The standardization of NK cell assays for the use in studies of biological response modifiers. J. Immunol. Methods 68, 235-249.
35. Risdahl, J., Peterson, P., Chao, C., Pijoan, C., Molitor, T., 1993. Effects of morphine dependency on the pathogenesis of swine herpes virus infection. J. Infect. Dis. 167, 1281-1287.
36. Shavit, Y., Lewis, J., Terman, G., Gale, R., Leibeskind, L., 1984. Opioid peptides mediate the suppressive effect of stress on natural killer cell cytotoxicity. Science 223, 188-190.
37. Shavit, Y., Terman, G., Lewis, J., Zane, C., Gale, R., Liebeskind, J., 1986. Effects of foot shock stress and morphine on natural killer lymphocytes in rats: studies of tolerance and crosstolerance. Brain Res. 372, 382-385.
38. Smith, M., Pitts, R., Dykstra, L., Picker, M., 1994. Effects of opioids with varying degrees of intrinsic efficacy at the mu receptor on fixed consecutive number responding in rats.. Soc. Neurosci. Abstr. 24th Annu. Meeting USA. 20, 227.
39. Tubaro, E., Avico, U., Santiangeli, C., Zuccaro, P., Cavollo, C., Pacifici, R., Croce, C., Borelli, G., 1985. Morphine and methadone impact on human phagocytic physiology. Int. J. Immunopharmacol. 7, 865-874.
40. Tubaro, E., Borelli, G., Croce, C., Cavallo, G., Santiangeli, C., 1983. Effect of morphine on resistance to infection. J. Infect. Dis. 148, 656-666.
41. Weber, R., Pert, A., 1987. Opiate action in the periaquaductal gray matter causes suppression of immune function. J. Cell Biochem. 12, 317.
42. Weber, R., Pert, A., 1989. The periaquaductal gray matter mediates opiate-induced immunosuppression. Science 245, 188-190.
43. Wybran, J., Appelboom, T., Famaey, J., Govaerts, A., 1979. Suggestive evidence for receptors for morphine and methionine-enkephalin on normal human blood lymphocytes. J. Immunol. 123, 1068-1070.