Intralesionally implanted cisplatin plus systemic carmustine for the treatment of brain tumor in rats

Journal of Surgical Oncology

Volumn 69, Issue 2, 1998, Pages 76-82

  Kong, Qingzhong ^a   Kleinschmidt Demasters, Bette K ^a   Lillehei, Kevin O ^a  

^a UNIVERSITY OF COLORADO   (United States)

Author keywords

9L gliosarcoma; Biodegradable polymer; Brain neoplasm; Carmustine; Chemotherapy; Cisplatin; Drug delivery; Sustained release

Indexed keywords

CARMUSTINE; CISPLATIN; OPLA; POLYMER; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; CANCER CHEMOTHERAPY; CANCER SURVIVAL; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFICACY; DRUG IMPLANTATION; DRUG POTENTIATION; EXPERIMENTAL NEOPLASM; FRONTAL LOBE; GLIOSARCOMA; HISTOPATHOLOGY; INTRACEREBRAL DRUG ADMINISTRATION; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; TREATMENT INDICATION;

ANIMALS; ANTINEOPLASTIC AGENTS; ANTINEOPLASTIC AGENTS, ALKYLATING; BRAIN NEOPLASMS; CARMUSTINE; CATHETERS, INDWELLING; CISPLATIN; DRUG ADMINISTRATION SCHEDULE; DRUG SYNERGISM; GLIOSARCOMA; INJECTIONS, INTRALESIONAL; MALE; RATS; RATS, INBRED F344; SURVIVAL ANALYSIS; TUMOR CELLS, CULTURED;

EID: 0031790758     PISSN: 00224790     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9098(199810)69:2<76::AID-JSO6>3.0.CO;2-9     Document Type: Article

References (29)

1. Lillehei KO, Kong Q, Withrow SJ, et al.: Cisplatin administered via sustained release biodegradable polymer appears superior to conventionally administered chemotherapy in the treatment of 9L gliosarcoma in rats. Proc Am Assoc Cancer Res 1994;35:417.
2. Lillehei KO, Kong Q, Withrow SJ, et al.: Efficacy of intralesional cisplatinum impregnated biodegradable polymer for the treatment of 9L gliosarcoma in the rat. Neurosurgery 1996;39:1191-1199.
3. Kong Q, Lillehei KO, Mitchell DH, et al.: Local sustained release of cisplatin from biodegradable polymer can cure 9L gliosarcoma in the rat. Proc Am Assoc Cancer Res 1993;34:365.
4. Kong Q, Kleinschmidt-DeMasters B, Lillehei KO: Intralesional implanted cisplatin cures primary brain tumors in rats. J Surg Oncol 1997;64:268-273.
5. Brem H, Mahaley MS Jr, Vick NA, et al.: Interstitial chemotherapy with drug polymer implants for the treatment of recurrent gliomas. J Neurosurg 1991;74:441-446.
6. Brem H, Piantadosi S, Burger PC, et al.: Placebo-controlled trial of safety and efficacy of intraoperative controlled delivery by biodegradable polymers of chemotherapy for recurrent gliomas. Lancet 1995;345:1008-1012.
7. Kong Q, Lillehei KO: Buffering ability of brain tumors against the side-effects of chemotherapy on rats. Proc Am Assoc Cancer Res 1998;39:590.
8. Dellian M, Walenta S, Kuhnle GE: Relation between autoradiographically measured blood flow and ATP concentrations obtained from imaging bioluminescence in tumors following hyperthermia. Int J Cancer 1993;53:785-791.
9. Okada Y, Kloiber O, Hossmann KA: Regional metabolism in experimental brain tumors in cats: Relationship with acid/base, water, and electrolyte homeostasis. J Neurosurg 1992;77:917-926.
10. Hunter EM, Sutherland LA. Cree IA, et al.: Heterogeneity of chemosensitivity in human breast carcinoma: Use of an adenosine triphosphate (ATP) chemiluminescence assay. Eur J Surg Oncol 1993;19:242-249.
11. Thompson SW, Davis LE, Kornfeld M, et al.: Cisplatin neuropathy: Clinical, electrophysiology, morphologic, and toxicologic studies. Cancer 1984;54:1269-1275.
12. Donelli MG, Zucchetti M, D'Incalci M: Do anticancer agents reach the tumor target in the human brain? Cancer Chemother Pharmacol 1992;30:251-260.
13. Stewart DS, Leavens M, Maor M, et al.: Human central nervous system distribution of cis-diamminedichloroplatinum and use as a radiosensitizer in malignant brain tumors. Cancer Res 1982;42: 2474-2479.
14. Straw RC, Withrow SJ, Douple EB, et al.: Effects of cis-diamminedichloroplatinum II released from D,L-polylactic acid implanted adjacent to cortical allografts in dogs. J Orthop Res 1994;12:871-877.
15. Jain RK: Vascular and interstitial barriers to delivery of therapeutic agents in tumors [review]. Cancer Metastasis Rev 1990;9:253-266.
16. Jain RK: Delivery of therapeutic agents Io solid tumors: Role of vascular and interstitial physiology [meeting abstract]. Proc Annu Meet Am Assoc Cancer Res 1994;35:661.
17. Less JR, Skalak TC, Sevick EM, et al.: Microvascular architecture in a mammary carcinoma: Branching patterns and vessel dimensions. Cancer Res 1991;51:265-273.
18. Schem BC, Roszinski S, Krossnes BK, et al.: Timing of hypertonic glucose and thermochemotherapy with 1-(4-amino-2-methylpyrimidine-5-yl)-methyl-3-(2-chloroethyl)-3-nitrosourea (ACNU) in the BT4An rat glioma: Relation to intratumoral pH reduction and circulatory changes after glucose supply. Int J Radiat Oncol Biol Phys 1995;33:409-416.
19. Choti M, Lee J, DeResta G, et al.: Effect of angiotensin II on interstitial hypertension in experimental hepatic colorectal metastases [meeting abstract]. Proc Annu Meet Am Assoc Cancer Res 1993;34:A2086.
20. Curti BD, Urba WJ, Alvord WG, et al.: Interstitial pressure of subcutaneous nodules in melanoma and lymphoma patients: Changes during treatment. Cancer Res 1993;53(10 Suppl):2204-2207.
21. Gutmann R, Leunig M, Feyh, et al.: Interstitial hypertension in head and neck tumors in patients: Correlation with tumor size. Cancer Res 1992;52:1993-1995.
22. Trotter MJ: Intermittent blood flow in the murine SCCVII squamous cell carcinoma. Diss Abstr Int B 1992;52:5206.
23. Tamargo RJ, Myseros JS, Epstein JI, et al.: Interstitial chemotherapy of the 9L gliosarcoma: Controlled release polymers for drug delivery in the brain. Cancer Res 1993;53:329-333.
24. Giese A, Westphal M: Glioma invasion in the central nervous system [review]. Neurosurgery 1996;39:235-250.
25. Fung LK, Ewend MG, Sills A, et al.: Pharmacokinetics of interstitial delivery of carmustine, 4-hydroperoxycyclophosphamide, and paclitaxel from a biodegradable polymer implant in the monkey brain. Cancer Res 1998;58:672-685.
26. Walter KA, Cahan MA, Gur A, et al.: Interstitial Taxol delivered from a biodegradable polymer implant against experimental malignant glioma. Cancer Res 1994;54:2207-2212.
27. Judy KD, Olivi A, Buahin KG, et al.: Effectiveness of controlled release of a cyclophosphamide derivative with polymers against rat gliomas. J Neurosurg 1995;82:481-486.
28. Jones JA, Albright KD, Christen RD, et al.: Synergy between tamoxifen and cisplatin in human melanoma cells is dependent on the presence of antiestrogen-binding sites. Cancer Res 1997;57: 2657-2660.
29. Ewend MG, Williams JA, Tabassi K, et al.: Local delivery of chemotherapy and concurrent external beam radiotherapy prolongs survival in metastatic brain tumor models. Cancer Res 1996; 56:5217-5223.