Enhancement of the oral bioavailability of phenytoin by N-acetylation and absorptive characteristics

Biological and Pharmaceutical Bulletin

Volumn 21, Issue 10, 1998, Pages 1084-1089

  Ogiso, Taro ^a   Tanino, Tadatoshi ^a   Kawaratani, Dai ^a   Iwaki, Masahiro ^a   Tanabe, Genzoh ^a   Muraoka, Osamu ^a  

^a KINKI UNIVERSITY   (Japan)

Author keywords

Absorption; Hydrolysis; Intestinal distribution; N acetylphenytoin; Pharmacokinetics; Solubility

Indexed keywords

HYDANTOIN; PHENYTOIN; PRODRUG;

ACETYLATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG DISTRIBUTION; DRUG HYDROLYSIS; DRUG SOLUBILITY; INTESTINE ABSORPTION; MALE; MICELLE; NONHUMAN; RAT;

EID: 0031790565     PISSN: 09186158     EISSN: None     Source Type: Journal    
DOI: 10.1248/bpb.21.1084     Document Type: Article

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