Adaptive changes in the pharmacodynamics of midazolam in different experimental models of epilepsy: Kindling, cortical stimulation and genetic absence epilepsy

British Journal of Pharmacology

Volumn 125, Issue 4, 1998, Pages 615-620

  Cleton, A ^a   Voskuyl, R A ^b,c   Danhof, M ^a  

^a LEIDEN UNIVERSITY   (Netherlands)

^b Instituut voor Epilepsiebestrijding   (Netherlands)

^c LEIDEN UNIVERSITY   (Netherlands)

Author keywords

aminobutyric acid; Benzodiazepines; Epilepsy; Kindling; Pharmacokinetic pharmacodynamic modelling

Indexed keywords

BENZODIAZEPINE DERIVATIVE; MIDAZOLAM;

ABSENCE; AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; ARTICLE; BRAIN CORTEX; CONTROLLED STUDY; ELECTROENCEPHALOGRAM; EXPERIMENTAL MODEL; FOURIER TRANSFORMATION; GABAERGIC SYSTEM; KINDLING; MALE; NONHUMAN; PHARMACODYNAMICS; PRIORITY JOURNAL; RAT;

AMYGDALA; ANIMALS; BENZODIAZEPINES; ELECTRIC STIMULATION; ELECTROENCEPHALOGRAPHY; EPILEPSY; INJECTIONS, INTRAVENOUS; KINDLING, NEUROLOGIC; MALE; MIDAZOLAM; RATS; RATS, WISTAR; RECEPTORS, GABA-A; TIME FACTORS;

EID: 0031789380     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0702088     Document Type: Article

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