Abnormalities of the FHIT transcripts in osteosarcoma and Ewing sarcoma

Japanese Journal of Cancer Research

Volumn 89, Issue 9, 1998, Pages 887-894

  Hinohara, Shin Ichi ^a   Satake, Noriko ^a   Sekine, Ki Ichi ^a   Kaneko, Yasuhiko ^a  

^a SAITAMA CANCER CENTER   (Japan)

Author keywords

Ewing sarcoma; FHIT; Osteosarcoma

Indexed keywords

MESSENGER RNA;

ADOLESCENT; ADULT; ARTICLE; CANCER CELL CULTURE; CLINICAL ARTICLE; EWING SARCOMA; EXON; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; OSTEOSARCOMA; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA SPLICING; RNA TRANSCRIPTION; SCHOOL CHILD; TUMOR SUPPRESSOR GENE;

EID: 0031788119     PISSN: 09105050     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1349-7006.1998.tb00645.x     Document Type: Article

References (25)

1. Link, M. P. and Eilber, F. Osteosarcoma. In "Principles and Practice of Pediatric Oncology," ed. P. A. Pizzo and D. G. Poplack, pp. 841-862 (1993). J. B. Lippincott Company, Philadelphia.
2. Feugeas, O., Guriec, N., Babin-Boilletot, A., Marcellin, L., Simon, P., Babin, S., Thyss, A., Hofman, P., Terrier, P., Kalifa, C., Brunat-Mentigny, M., Patricot, L. and Oberling, F. Loss of heterozygosity of the RB gene is a poor prognostic factor in patients with osteosarcoma. J. Clin. Oncol., 14, 467-472 (1996).
3. Toguchida, J., Yamaguchi, T., Ritchie, B., Beauchamp, R. L., Dayton, S. H., Herrera, G. E., Yamamuro, T., Kotoura, Y., Sasaki, M. S., Little, J. B., Weichselbaum, R. R., Ishizaki, K. and Yandell, D. W. Mutation spectrum of the p53 gene in bone and soft tissue sarcomas. Cancer Res., 52, 6194-6199 (1992).
4. Wadayama, B., Toguchida, J., Shimizu, T., Ishizaki, K., Sasaki, M. S., Kotoura, Y. and Yamamuro, T. Mutation spectrum of the retinoblastoma gene in osteosarcomas. Cancer Res., 54, 3042-3048 (1994).
5. Delattre, O., Zucman, J., Plougastel, B., Desmaze, C., Melot, T., Peter, M., Kovar, H., Joubert, I., de Jong, P., Rouleau, G., Aurias, A. and Thomas, G. Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumours. Nature, 359, 162-165 (1992).
6. Zucman, J., Melot, T., Desmaze, C., Ghysdael, J., Plougastel, B., Peter, M., Zucker, J. M., Triche, T. J., Sheer, D., Turc-Carel, C., Ambros, P., Combaret, V., Lenoir, G., Aurias, A., Thomas, G. and Delattre, O. Combinatorial generation of variable fusion proteins in the Ewing family of tumours. EMBO J., 12, 4481-4487 (1993).
7. Sorensen, P. H. B., Lessnick, S. L., Lopez-Terrada, D., Liu, X. F., Triche, T. J. and Denny, C. T. A second Ewing's sarcoma translocation, t(21;22), fuses the EWS gene to another ETS-family transcription factor. ERG. Nat. Genet., 6, 146-151 (1994).
8. Ohta, M., Inoue, H., Cotticelli, M. G., Kastury, K., Baffa, R., Palazzo, J., Siprashvili, Z., Mori, M., McCue, P., Druck, T., Croce, C. M. and Huebner, K. The FHIT gene, spanning the chromosome 3p14.2 fragile site and renal carcinoma-associated t(3;8) breakpoint, is abnormal in digestive tract cancers. Cell. 84, 587-597 (1996).
9. Thiagalingam, S., Lisitsyn, N. A., Hamaguchi, M., Wigler, M. H., Willson, J. K. V., Markowitz, S. D., Leach, F. S., Kinzler, K. W. and Vogelstein, B. Evaluation of the FHIT gene in colorectal cancers. Cancer Res., 56, 2936-2939 (1996).
10. Sozzi, G., Veronese, M. L., Negrini, M., Baffa, R., Cotticelli, M. G., Inoue, H., Tornielli, S., Pilotti, S., Gregorio, L. D., Pastorino, U., Pierotti, M. A., Ohta, M., Huebner, K. and Croce, C. M. The FHIT gene at 3p14.2 is abnormal in lung cancer. Cell, 85, 17-26 (1996).
11. Negrini, M., Monaco, C., Vorechovsky, I., Ohta, M., Druck, T., Baffa, R., Huebner, K. and Croce, C. M. The FHIT gene at 3p14.2 is abnormal in breast carcinomas. Cancer Res., 56, 3173-3179 (1996).
12. Mao, L., Fan, Y., Lotan, R. and Hong, W. K. Frequent abnormalities of FHIT, a candidate tumor suppressor gene, in head and neck cancer cell lines. Cancer Res., 56, 5128-5131 (1996).
13. Virgilio, L., Shuster, M., Gollin, S. M., Veronese, M. L., Ohta, M., Huebner, K. and Croce, C. M. FHIT gene alterations in head and neck squamous cell carcinomas. Proc. Natl. Acad. Sci. USA, 93, 9770-9775 (1996).
14. Sozzi, G., Alder, H., Tornielli, S., Corletto, V., Baffa, R., Veronese, M. L., Negrini, M., Pilotti, S., Pierotti, M. A., Huebner, K. and Croce, C. M. Aberrant FHIT transcripts in Merkel cell carcinoma. Cancer Res., 56, 2472-2474 (1996).
15. Sozzi, G., Tornielli, S., Tagliabue, E., Sard, L., Pezzella, F., Pastorino, U., Minoletti, F., Pilotti, S., Ratcliffe, C., Veronese, M. L., Goldstraw, P., Huebner, K., Croce, C. M. and Pierotti, M. A. Absence of Fhit protein in primary lung tumors and cell lines with FHIT gene abnormalities. Cancer Res., 57, 5207-5212 (1997).
16. Panagopoulos, I., Thelin, S., Mertens, F., Mitelman, F. and Aman, P. Variable FHIT transcripts in non-neoplastic tissues. Genes Chromosom. Cancer, 19, 215-219 (1997).
17. van den Berg, A., Draaijers, T. G., Kok, K., Timmer, T., van der Veen, A. Y., Veldhuis, P. M. J. F., de Leij, L., Gerhartz, C. D., Naylor, S. L., Smith, D. I. and Buys, C. H. C. M. Normal FHIT transcripts in renal cell cancer- and lung cancer-derived cell lines, including a cell line with a homozygous deletion in the FRA3B region. Genes Chromosom. Cancer, 19, 220-227 (1997).
18. Tsujimoto, Y., Yunis, J., Onorato-Showe, L., Erikson, J., Nowell, P. C, and Croce, C. M. Molecular cloning of the chromosomal breakpoint of B-cell lymphomas and leukemias with the t(11;14) chromosome translocation. Science, 224, 1403-1406 (1984).
19. Satake, N., Maseki, N., Kozu, T., Sakashita, A., Kobayashi, H., Sakurai, M., Ohki, M. and Kaneko, Y. Disappearance of AML1-MTG8(ETO) fusion transcript in acute myeloid leukaemia patients with t(8;21) in long-term remission. Br. J. Haematol., 91, 892-898 (1995).
20. Nakajima-Iijima, S., Hamada, H., Reddy, P. and Kakunaga, T. Molecular structure of the human cytoplasmic β-actin gene: interspecies homology of sequences in the introns. Proc. Natl. Acad. Sci. USA, 82, 6133-6137 (1985).
21. Kaplan, E. L. and Meier, P. Nonparametric estimation for incomplete observation. J. Am. Stat. Assoc., 53, 457-187 (1958).
22. Peto, R. and Peto, J. Asymptotically efficient rank variant test procedures. J. R. Stat. Soc. (A), 135, 185-206 (1972).
23. Ong, S. T., Fong, K. M., Bader, S. A., Minna, J. D., Le Beau, M., McKeithan, T. W., and Rassool, F. V. Precise localization of the FHIT gene to the common fragile site at 3p14.2 (FRA3B) and characterization of homozygous deletions within FRA3B that affect FHIT transcription in tumor cell lines. Genes Chromosom. Cancer, 20, 16-23 (1997).
24. Komuro, H., Hayashi, Y., Kawamura, M., Hayashi, K., Kaneko, Y., Kamoshita, S., Hanada, R., Yamamoto, K., Hongo, T., Yamada, M. and Tsuchida, Y. Mutations of the p53 gene are involved in Ewing's sarcomas but not in neuroblastomas. Cancer Res., 53, 5284-5288 (1993).
25. Kovar, H., Auinger, A., Jug, G., Aryee, D., Zoubek, A., Salzer-Kuntschik, M. and Gadner, H. Narrow spectrum of infrequent p53 mutations and absence of MDM2 amplification in Ewing tumours. Oncogene, 8, 2683-2690 (1993).