N-myc transactivates RCC1 gene expression in rat fibroblast cells transformed by N-myc and v-ras

Journal of Biochemistry

Volumn 124, Issue 5, 1998, Pages 1013-1019

  Tsuneoka, Makoto ^a   Mekada, Eisuke ^a  

^a KURUME UNIVERSITY   (Japan)

Author keywords

E box element; Gene expression; N myc; RCC1; Transformation

Indexed keywords

DNA FRAGMENT;

ANIMAL CELL; ARTICLE; CELL PROLIFERATION; CELL TRANSFORMATION; FIBROBLAST CULTURE; NONHUMAN; ONCOGENE C MYB; ONCOGENE RAS; PROMOTER REGION; RAT; TRANSACTIVATION; VIRUS ONCOGENE;

ANIMALIA; EUKARYOTA;

EID: 0031787699     PISSN: 0021924X     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.jbchem.a022193     Document Type: Article

References (49)

1. Schwab, M., Alitalo, K., Klempnauer, K.-H., Varmus, H.E., Bishop, J.M., Gilbert, F., Brodeur, G., Goldstein, M., and Trent, J. (1983) Amplified DNA with limited homology to myc cellular oncogene is shared by human neuroblastoma cell lines and a neuroblastoma tumour. Nature 305, 245-248
2. Lee, W.-H., Murphree, A.L., and Benedict, W.F. (1984) Expression and amplification of the N-myc gene in primary retinoblastoma. Nature 309, 458-460
3. Nau, M.M., Brooks, Jr. B.J., Carney, D.N., Gazdar, A.F., Battey, J.F., Sausville, E.A., and Minna, J.D. (1986) Human small-cell lung cancers show amplification and expression of the N-myc gene. Proc. Natl. Acad. Sci. USA 83, 1092-1096
4. Brodeur, G.M., Seeger, R.C., Schwab, M., Varmus, H.E., and Bishop, J.M. (1984) Amplification of N-myc in untreated human neuroblastomas correlated with advanced disease stage. Science 224, 1121-1124
5. Kohl, N.E., Gee, C.E., and Alt, F.W. (1984) Activated expression of the N-myc gene in human neuroblastomas and related tumors. Science 226, 1335-1337
6. Weiss, W.A., Aldape, K., Mohapatra, G., Feuerstein, B.G., and Bishop, J.M. (1997) Targeted expression of MYCN causes neuroblastoma in transgenic mice. EMBO J. 16, 2985-2995
7. Morgenbesser, S.D. and DePinho, H.A. (1994) Use of transgenic mice to study myc family gene function in normal mammalian development and in cancer. Semin. Cancer Biol. 5, 21-36
8. Henriksson, M. and Lüscher, B. (1996) Proteins of the Myc network: essential regulators of cell growth and differentiation. Adv. Cancer Res. 68, 109-182
9. Tsuneoka, M., Nakano, F., Ohgusu, H., and Mekada, E. (1997) c-myc activates RCC1 gene expression through E-box elements. Oncogene 14, 2301-2311
10. Nishimoto, T., Eilen, E., and Basilico, C. (1978) Premature chromosome condensation in a ts DNA mutant of BHK cells. Cell 15, 475-483
11. Matsumoto, T. and Beach, D. (1991) Premature initiation of mitosis in yeast lacking RCC1 or an interacting GTPase. Cell 66, 347-360
12. Ohtsubo, M., Okazaki, H., and Nishimoto, T. (1989) The RCC1 protein, a regulator for the onset of chromosome condensation locates in the nucleus and binds to DNA. J. Cell. Biol. 109, 1389-1397
13. Bishoff, F.R. and Ponstingl, H. (1991) Catalysis of guanine nucleotide exchange on Ran by the mitotic regulator RCC1. Nature 354, 80-82
14. Bishoff, F.R. and Ponstingl, H. (1991) Mitotic regulator protein RCC1 is complexed with a nuclear ras-related polypeptide. Proc. Natl. Acad. Sci. USA 88, 10830-10834
15. Dasso, M., Nishitani, H., Kornbluth, S., Nishimoto, T., and Newport, J.W. (1992) RCC1, a regulator of mitosis, is essential for DNA replication. Mol. Cell. Biol. 12, 3337-3345
16. Dasso, M., Seki, T., Azuma, Y., Ohba, T., and Nishimoto, T. (1994) A mutant form of the Ran/TC4 protein disrupts nuclear function in Xenopus leavis egg extracts by inhibiting the RCC1 protein, a regulator of chromosome condensation. EMBO J. 13, 5732-5744
17. Ren, M., Drivas, G., D'Eustachio, P., and Rush, M.G. (1993) Ran/TC4: a small nuclear GTP-binding protein that regulates DNA synthesis. J. Cell. Biol. 120, 313-323
18. Moore, M.S. and Blobel, G. (1993) The GTP-binding protein Ran/TC4 is required for protein import into the nucleus. Nature 365, 661-663
19. Tachibana, T., Imamoto, N., Seino, H., Nishimoto, T., and Yoneda, Y. (1994) Loss of RCC1 leads to suppression of nuclear protein import in living cells. J. Biol. Chem. 269, 24542-24545
20. + RNA in the cytoplasm. Proc. Natl. Acad. Sci. USA 92, 225-229
21. Kadowaki, T., Goldfarb, D., Spitz, L.M., Tartakoff, A.M., and Ohno, M. (1993) Regulation of RNA processing and transport by a nuclear guanine nucleotide release protein and members of the Ras superfamily. EMBO J. 12, 2929-2937
22. Amberg, D.C., Fleischmann, M., Stagljar, I., Cole, C.N., and Aebi, M. (1993) Nuclear PRP20 protein is required for mRNA export. EMBO J. 12, 233-241
23. Rush, M.G., Drivas, G., and D'Eustachio, P. (1996) The small nuclear GTPase Ran: how much does it run. BioEssays 18, 103-112
24. Grandori, C. and Eisenman, R.N. (1997) Myc target genes. Trends Biochem. Sci. 22, 177-181
25. Bello-Fernandez, C., Packham, G., and Cleveland, J.L. (1993) The ornithine decarboxylase gene is a transcriptional target of c-Myc. Proc. Natl. Acad. Sci. USA 90, 7804-7808
26. Reisman, D., Elkind, N.B., Roy, B., Beamon, J., and Rotter, V. (1993) c-Myc trans-activates the p53 promoter through a required downstream CACGTG motif. Cell Growth Differ. 4, 57-65
27. Benvenisty, N., Leder, A., Kuo, A., and Leder, P. (1992) An embryonically expressed gene is a target for c-Myc regulation via the c-Myc-binding sequence. Genes Dev. 6, 2513-2523
28. Gaubatz, S., Meichle, A., and Eilers, M. (1994) An E-box element localized in the first intron mediates regulation of the prothymosin α gene by c-myc. Mol. Cell. Biol. 14, 3853-3862
29. Miltenberger, R.J., Sukow, K.A., and Farnham, P.J. (1995) An E-box-mediated increase in cad transcription at the G1/S-phase boundary is suppressed by inhibitory c-Myc mutants. Mol. Cell. Biol. 15, 2527-2535
30. Galaktionov, K., Chen, X., and Beach, D. (1996) Cdc25 cell-cycle phosphatase as a target of c-myc. Nature 382, 511-517
31. Jones, R.M., Branda, J., Johnston, K.A., Polymenis, M., Gadd, M., Rustgi, A., Callanan, L., and Schmidt, E.V. (1996) An essential E box in the promoter of the gene encoding the mRNA Cap-binding protein (eukaryotic Initiation Factor 4E) is a target for activation by c-myc. Mol. Cell. Biol. 16, 4754-4764
32. Grandori, C., Mac, J., Siëbelt, F., Ayer, D.E., and Eisenman, R.N. (1996) Myc-Max heterodimers activate a DEAD box gene and interact with multiple E box-related sites in vivo. EMBO J. 15, 4344-4357
33. Shim, H., Dolde, C., Lewis, B.C., Wu, C.-S., Dang, G., Jungmann, R.A., Dalla-Favera, R., and Dang, C.V. (1997) c-Myc transactivation of LDH-A: Implications for tumor metabolism and growth. Proc. Natl. Acad. Sci. USA 94, 6658-6663
34. Tobias, K.E., Shor, J., and Kahara, C. (1995) c-Myc and Max transregulate the mouse ornithine decarboxylase promoter through interaction with two downstream CACGTG motifs. Oncogene 10, 1771-1727
35. Desbarats, L., Gaubatz, S., and Eilers, M. (1996) Discrimination between different E-box-binding proteins at an endogenous target gene of c-myc. Genes Dev. 10, 447-460
36. Eilers, M., Picard, D., Yamamoto, K.R., and Bishop, J.M. (1989) Chimaeras of Myc oncoprotein and steroid receptors cause hormone-dependent transformation of cells. Nature 340, 66-68
37. Kato, K., Kanamori, A., and Kondoh, H. (1990) Rapid and transient decrease of N-myc expression in retinoic acid-induced differentiation of OTF9 teratocarcinoma stem cells. Mol. Cell. Biol. 10, 486-491
38. Gossen, M. and Bujard, H. (1992) Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. Proc. Natl. Acad. Sci. USA 89, 5547-5551
39. Sanger, F., Nicklen, S., and Coulson, A.R. (1977) DNA sequencing with chain-terminating inhibitors. Proc. Natl. Acad. Sci. USA 74, 5463-5467
40. Tsuchida, N., Ryder, T., and Ohtsubo, E. (1982) Nucleotide sequence of the oncogene encoding the p21 transforming protein of Kirsten Murine Sarcoma Virus. Science 217, 937-939
41. Kimura, G., Itagaki, A., and Summers, J. (1975) Rat cell line 3Y1 and its virogenic polyoma- and SV40-transformed derivatives. Int. J. Cancer 15, 694-706
42. Chen, C.A. and Okayama, H. (1988) Calcium phosphate-mediated gene transfer: a high efficient transfection system for stably transforming cells with plasmid DNA. Biotechniques 6, 632-638
43. Ohtsubo, M., Kai, R., Furuno, N., Sekiguchi, T., Sekiguchi, M., Hayashida, H., Kuma, K., Miyata, T., Fukushige, S., Murotsu, T., Matsubara, K., and Nishimoto, T. (1987) Isolation and characterization of the active cDNA of the human cell cycle gene (RCC1) involved in the regulation of onset of chromosome condensation. Genes Dev. 1, 585-593
44. Chomczynski, P. and Sacchi, N. (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162, 156-159
45. Sambrook, J., Fritsch, E.F., and Maniatis, T. (1989) Molecular Cloning; A Laboratory Manual, 2nd ed., Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
46. Blackwood, E.M. and Eisenman, R.N. (1991) Max: a helix-loop-helix zipper protein that forms a sequence-specific DNA-binding complex with Myc. Science 251, 1211-1217
47. Prendergast, G.C., Lawe, D., and Ziff, E.B. (1991) Association of Myn, the murine homolog of Max, with c-Myc stimulates methylation-sensitive DNA binding and Ras cotransformation. Cell 65, 395-407
48. Norton, P.A. and Coffin, J.M. (1985) Bacterial β-galactosidase as a marker of raus sarcoma virus gene expression and replication. Mol. Cell. Biol. 5, 281-290
49. Yamashita, T., Yamamoto, K., Shiroki, K., Kimura, G., Matsui, K., Osato, T., Shimojo, H., and Fujinaga, K. (1980) Chromosomal alterations of rat cell lines transformed by human adenovirus type-12 virion, whole DNA and left-end DNA fragments. Int. J. Cancer 26, 435-442