A membrane-lytic immunoconjugate selective for human tumor T-lymphocytes

International Journal of Immunopharmacology

Volumn 20, Issue 9, 1998, Pages 467-478

  Hinman, Channing L ^a   Tang, Hai Ping ^a  

^a MEDICAL COLLEGE OF OHIO   (United States)

Author keywords

Cancer; Cytotoxin; Immunoconjugate; Membrane lytic toxin; Monoclonal antibody

Indexed keywords

ANTIBODY CONJUGATE; IMMUNOTOXIN; SNAKE VENOM;

ARTICLE; CANCER CELL; CELL PROLIFERATION; IMMUNOGENICITY; PRIORITY JOURNAL; T LYMPHOCYTE; TARGET CELL;

ANIMALS; CELL MEMBRANE; CYTOTOXINS; FEMALE; HUMANS; IMMUNOTOXINS; LEUKEMIA L1210; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED BALB C; NEOPLASMS; T-LYMPHOCYTES; TUMOR CELLS, CULTURED;

EID: 0031783099     PISSN: 01920561     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0192-0561(98)00053-8     Document Type: Article

References (27)

1. Arms, K., & McPheeters, D. (1975). Sensitivity of cultured embryonic heart cells to cardiotoxin obtained from Naja naja siamensis venom. Toxicon, 13, 333-338.
2. Avila, A. D., Mateo De Acosta, C., & Lage, A. (1988). A new immunotoxin built by linking a hemolytic toxin to a monoclonal antibody specific for immature T lymphocytes. Int. J. Cancer, 42, 568-571.
3. Bernheimer, A. W., & Rudy, B. (1986). Interactions between membranes and cytolytic peptides. Biochim. Biophys. Acta, 864, 123-141.
4. Bhaskaran, R., Huang, C. C., Chang, D. K., & Yu., C. (1994). Cardiotoxn III from the Taiwan Cobra (Naja naja atra) - Determination of structure in solution and comparison with short neurotoxins. J. Molec. Biol., 235, 1291-1301.
5. 2 activities. Biochemistry, 25, 7235-7243.
6. Carlsson, J., Drevin, H., & Axen, R. (1978). Protein thiolation and reversible protein-protein conjugation. N-succinimidyl 3-(2 pyridyldithio) propionate, a new heterobifunctional reagent. Biochem. J., 173, 723-737.
7. Chang, L.-S., Lin, J., & Wu, P.-F. (1997). cDNA sequence analysis of cardiotoxin variants from Taiwan cobra. Biochem. Molec. Biol. Int., 42, 85-92.
8. Chang, L. S., Wu, P. F., & Lin, J. (1996). cDNA sequence analysis and expression of cardiotoxins from Taiwan cobra. Biochem. Biophys. Res. Comun., 219, 116-121.
9. Chi, L.-M., Vyas, A. A., Rule, G. S., & Wu, W. G. (1994). Expression of glutathione S-transferase-cardiotoxin fusion protein in Escherichia coli. Toxicon, 32, 1679-1683.
10. Chiou, S. H., Hung, C. C., Huang, H. C., Chen, S. T., Wang, K. T., & Yang, C. C. (1995). Sequence comparison and computer modelling of cardiotoxins and cobrotoxin isolated from Taiwan cobra. Biochem. Biophys. Res. Commun., 206, 22-32.
11. Drobniewski, F. A. (1989). Immunotoxins up to the present day. Biosci. Reports, 9, 139-156.
12. Drobniewski, F. A., Watson, G. J., Wawrzynczak, E. J., Alouf, J. E., & Thorpe, P. E. (1992). A novel membrane-acting immunotoxin, the immunolysin, with therapeutic potential. Biochem. Soc. Trans., 20, 318S.
13. Drori, S., Eytan, G. D., & Assaraf, Y. G. (1995). Potentiation of anticancer-drug cytotoxicity by multidrug-resistance chemosensitizers involves alterations in membrane fluidity leading to increased membrane permeability. Eur. J. Biochem., 228, 1020-1029.
14. Du, Y. C., Shen, J. H., Wu, W. Y., Wu, C. R., Wang, K. Z., Gu, B. X., & Fu, P. (1986). Chemical synthesis of Indian cobra cytotoxin II by solid-phase condensation of fragments. Biopolymers, 25, S85-S96.
15. Gasanov, S. E., Rael, E. D., Gasanov, N. E., & Vernon, L. P. (1995). In vitro evaluation of Pyrularia thionin - anti-CD5 immunotoxin. Cancer Immunol. Immunother, 41, 122-128.
16. Harvey, A. L., Marshall, R. J., & Karlsson, E. (1982). Effects of purified cardiotoxins from the Thailand cobra [Naja naja siamensis] on isolated skeletal and cardiac muscle preparations. Toxicon, 20, 379-396.
17. Hinman, C. L., Jiang, X.-L., & Tang, H.-P. (1990). Selective cytolysis by a protein toxin as a consequence of direct interaction with the lymphocyte plasma membrane. Toxicol. Appl. Pharmacol., 104, 290-300.
18. Karlsson, E., Arnberg, H., & Eaker, D. (1971). Isolation of the principal neurotoxins of two Naja naja subspecies. Eur. J. Biochem., 21, 1-16.
19. Kumar, T. K. S., Yang, P. W., Lin, S. H., Wu, C. Y., Lei, B., Lo, S. J., Tu, S. C., & Yu, C. (1996). Cloning direct expression, and purification of a snake venom cardiotoxin in Escherichia coli. Biochem. Biophys. Res. Commun., 219, 450-456.
20. Pastan, I., Willingham, M. C., & FitzGerald, D. J. P. (1986). Immunotoxins. Cell, 47, 641-648.
21. Saberwal, G., & Nagaraj, R. (1994). Cell-lytic and antibacterial peptides that act by perturbing the barrier function of membranes: facets of their conformational features, structure-function correlations and membrane-perturbing abilities. Biochim. Biophys. Acta, 1197, 109-131.
22. Stevens-Truss, R., & Hinman, C. L. (1997). Activities of cobra venom cytotoxins toward heart and leukemic T cells depend on localized amino acid differences. Toxicon, 35, 659-669.
23. Stevens-Truss, R., Messer, W. S., Jr, & Hinman, C. L. (1996). Heart and T-lymphocyte cell surfaces both exhibit positive cooperativity in binding a membrane-lytic toxin. J. Membr. Biol., 150, 113-122.
24. Thrush, G. R., Lark, L. R., Clinchy, B. C., & Vitetta, E. S. (1996). Immunotoxins: an update. Ann. Rev. Immunol., 14, 49-71.
25. Wu, C.-Y., Chen, W.-C., Ho, C-L., Chen, S.-T., & Wang, K.-T. (1997). The role of the N-terminal leucine residue in snake venom cardiotoxin II (Naja naja atra). Biochem. Biophys. Res. Comm., 233, 713-716.
26. Wu, M. (1997). Enhancement of immunotoxin activity using chemical and biological reagents. Brit. J. Cancer, 75, 1347-1355.
27. Zheng, B., Chambers, T. C., Raynor, R. L., Markham, P. N., Gebel, H. M., Vogler, W. R., & Kuo, J. R. (1994). Human leukemia K562 cell mutant (K562/OA200) selected for resistance to okadaic acid (protein phosphatase inhibitor) lacks protein kinase C-e, exhibits multidrug resistance phenotype, and expresses drug pump P-glycoprotein. J. Biol. Chem., 269, 12332-12338.