Status of cytokine and antigen presentation genes in Merkel cell carcinoma of the skin

Journal of Cutaneous Medicine and Surgery

Volumn 2, Issue 3, 1998, Pages 138-141

  Arany, Istvan ^a   Tyring, Stephen K ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLINE; CYTOKERATIN; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 12; INTERLEUKIN 2; MESSENGER RNA; PROTEIN KINASE; PROTEIN P53;

AGED; ANTIGEN PRESENTATION; ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CLINICAL ARTICLE; EPITHELIUM CELL; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNE RESPONSE; MERKEL CELL TUMOR; NEUROSECRETORY CELL; ONCOGENE C MYC; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SKIN BIOPSY; SKIN CANCER; T LYMPHOCYTE; TUMOR GROWTH;

EID: 0031781732     PISSN: 12034754     EISSN: None     Source Type: Journal    
DOI: 10.1177/120347549800200305     Document Type: Article

References (31)

1. Ratner D, Nelson BR, Brown MD, et al. Merkel cell carcinoma. J Am Acad Dermatol 1993; 29:143-156.
2. Nickoioff BJ, Naidu Y. Perturbation of epidermal barrier function correlates with initiation of cytokine cascade in human skin. J Am Acad Dermatol 1994; 30:535-546.
3. Matsue H, Cruz Jr PD, Bergstresser PR, et al. Cytokine expression by epidermal cell subpopulations. J Invest Dermatol 1992; 99:42S-45S.
4. Arany I, Tyring SK. Status of local cellular immunity in interferon-responsive and -nonresponsive human papillomavirus-associated lesions. Sex Transm Dis 1996; 26:475-480.
5. Arany I, Brysk MM, Brysk H, et al. Response to interferon treatment decreases with epidermal dedifferentiation in condylomas. Antiviral Res 1996; 32:19-26.
6. Arany I, Tyring SK. Activation of local cell-mediated immunity in interferon-responsive patients with human papillomavirus-associated lesions. J Interferon Cytokine Res 1996; 16:453-460.
7. Szadowska A, Wozniak L, Lasota J, et al. Neuroendocrine (Merkel cell) carcinoma of the skin: a clinico-morphological study of 13 cases. Histopathology 1989; 15:483-493.
8. Vastrik I, Makela TP, Koskinen PJ, et al. Myc protein: partners and antagonists. Crit Rev Oncogen 1994; 5:59-68.
9. Hunter T, Pines J. Cyclins and cancer. Cell 1991; 66:1071-1074.
10. Farnham PJ, Slansky JE, Kollmar R. The role of E2F in the mammalian cell cycle. Biochim Biophys Acta 1993; 1155:125-131.
11. Miyagawa S, Okada N, Takasaki Y, et al. Expression of proliferating cell nuclear antigen/cyclin in human keratinocytes. J Invest Dermatol 1989; 93:678-681.
12. Arany I, Rady P, Evers BM, et al. Analysis of multiple molecular changes in human endocrine tumours. Surg Oncol 1994; 3:153-159.
13. Fuchs E. Epidermal differentiation: the bare essentials. J Cell Biol 1990; 111:2807-2814.
14. Nigro JM, Baker SJ, Preisinger AC, et al. Mutations in the p53 gene occur in diverse human tumor types. Nature 1989; 342:705-708.
15. Basset-Sequin N, Moles J-P, Mils V, et al. TP53 tumor suppressor gene and skin carcinogenesis. J Invest Dermatol 1994; 103:102S-106S.
16. Moles J-P, Moyret C, Guillot B, et al. p53 gene mutations in human epithelial skin cancers. Oncogene 1993; 8:
17. Ziegler A, Leffel DJ, Kunala S, et al. Mutation hotspots due to sunlight in the p53 gene of nonmelanoma skin cancers. Proc Natl Acad Sci USA 1993; 90:4216-4220.
18. Brash DE, Rudolph JA, Simon JA, et al. A role for sunlight in skin cancer: UV-induced p53 mutations in squamous cell carcinoma. Proc Natl Acad Sci USA 1991; 88:10124-10128.
19. Schmid M, Janssen K, Dockhorn-Dworncziak B, et al. p53 abnormalities are rare events in neuroendocrine (Merkel cell) carcinoma of the skin. An immunohistochemical and SSCP analysis. Virchows Arch 1997; 430:233-237.
20. Davidoff AM, Pence JC, Shorter NA, et al. Expression of p53 in human neuroblastoma- and neuroepithelioma-derived cell lines. Oncogene 1992; 7:127-133.
21. Weinberg RA. The retinoblastoma gene and cell growth control. Trends Biochem Sci 1990; 15:199-202.
22. Tuschil A, Lam C, Haslberger A, et al. Interleukin-8 stimulates calcium transients and promotes epidermal cell proliferation. J Invest Dermatol 1992; 99:294-298.
23. Booth C, Potten CS. Effects of IL-11 on the growth of intestinal epithelial cells in vitro. Cell Prolif 1995; 28:581-594.
24. Peterson RL, Bozza MM, Dorner AJ. Interleukin-11 induces intestinal epithelial cell growth arrest through effects on retinoblastoma protein phosphorylation. Am J Pathol 1996; 149:895-902.
25. Nickoloff BJ, Turka LA. Keratinocytes: key immunocytes of the integument. Am J Pathol 1993; 143:325-331.
26. Williams IR, Kupper TS. Immunity at the surface: homeostatic mechanisms of the skin immune system. Life Sci 1996; 58: 1485-1507.
27. Dezutter-Dambuant C. Role of Langerhans cells in cutaneous immunologic processes. Semin Dermatol 1988; 7:163-170.
28. Scott P, Kaufmann SHE. The role of T-cell subtypes and cytokines in the regulation of infection. Immunol Today 1991; 12:346-348.
29. Moll I, Bladt U, Jung EG. Presence of Merkel cells in sun-exposed and not sun-exposed skin: a quantitative study. Arch Dermatol Res 1990; 282:213-216.
30. Enk CD, Sredni D, Blauvelt A, et al. Induction of IL-10 gene expression in human keratinocytes by UVB exposure in vivo and in vitro. J Immunol 1995; 154:4851-4856.
31. Kim J, Modlin RL, Moy RL, et al. IL-10 production in cutaneous basal and squamous cell carcinomas. A mechanism for evading the local T cell immune response. J Immunol 1995; 155: 2240-2247.