Expression of an orphan nuclear receptor DAX-1 in human pituitary adenomas

Clinical Endocrinology

Volumn 48, Issue 5, 1998, Pages 647-654

  Ikuyama, Shoichiro ^a   Mu, Yi Ming ^a   Ohe, Kenji ^a   Nakagaki, Hiroyuki ^b   Fukushima, Takeo ^c   Takayanagi, Ryoichi ^a   Nawata, Hajime ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b Shin Kokura Hospital   (Japan)

^c FUKUOKA UNIVERSITY HOSPITAL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; CELL NUCLEUS RECEPTOR; GONADORELIN RECEPTOR; GROWTH HORMONE; PROLACTIN;

ARTICLE; CLASSIFICATION; HORMONE RELEASE; HYPOPHYSIS ADENOMA; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ADENOMA; DNA-BINDING PROTEINS; FOLLICLE STIMULATING HORMONE; FOLLICLE STIMULATING HORMONE, BETA SUBUNIT; GENE EXPRESSION; GROWTH HORMONE; HUMANS; LUTEINIZING HORMONE; PITUITARY NEOPLASMS; POLYMERASE CHAIN REACTION; PROLACTIN; PROLACTINOMA; RECEPTORS, LHRH; RECEPTORS, RETINOIC ACID; REPRESSOR PROTEINS; THYROTROPIN; TRANSCRIPTION FACTOR PIT-1; TRANSCRIPTION FACTORS;

EID: 0031778162     PISSN: 03000664     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2265.1998.00477.x     Document Type: Article

References (28)

1. Alexander, J.M., Biller, B.M.K., Bikkal, H., Zervas, N.T., Arnold, A & Klibanski, A. (1990) Clinically nonfunctioning pituitary tumors are monoclonal origin. Journal of Clinical Investigation, 86, 336-340.
2. Andersen, B. & Rosenfeld, M.G. (1994) Pit-1 determines cell types during development of the anterior pituitary gland. Journal of Biological Chemistry, 269, 29335-29338.
3. Asa, S.L., Puy, L.A., Lew, A.M., Sundmark. V.C. & Elshotz, H.P. (1993) Cell type-specific expression of the pituitary transcription activator pit-1 in the human pituitary and pituitary adenomas. Journal of Clinical Endocrinology & Metabolism, 77, 1275-1280.
4. Asa, S., Bamberger, A.-M., Cao, B., Wong, M., Parker, K.L. & Ezzat, S. (1996) The transcription activator steroidogenic factor-1 is preferentially expressed in the human pituitary gonadotroph. Journal of Clinical Endocrinology Metabolism, 81, 2165-2170.
5. Bardoni, B., Zanaria, E., Guioli, S., Floridia, G., Worley, K.C., Tonini, G.T., Ferrante, E., Chiumello, G., McCabe, E.R.B., Fraccaro, M., Auffardi, W., Camerino, G. (1994) A dosage sensitive locus at chromosome Xp21 is involved in male to female sex reversal. Nature Genetics, 7, 497-501.
6. Barnhart, K.M. & Mellon, P.L. (1994) The orphan nuclear receptor, steroidogenic factor-1, regulates the glycoprotein hormone α-subunit gene in pituitary gonadotropes. Molecular Endocrinology, 8, 878-885.
7. Burrs, T.P., Guo, W., Le, T. and McCabe, E.R.B. (1995) Identification of a putative steroidogenic factor-1 response element in the DAX-1 promoter. Biochemical and Biophysical Research Communications, 214, 576-581.
8. Chomczynski, P. & Sacchi, N. (1987) Single-step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction. Analytical Biochemistry, 162, 156-159.
9. Friend, K.E., Chiou, Y.K., Laws, Jr, E.R., Lopes, M.B.S. & Shupnik, M.A. (1993) Pit-1 messenger ribonucleic acid is differentially expressed in human pituitary adenomas. Journal of Clinical Endocrinology & Metabolism, 77, 1281-1286.
10. Guo, W., Mason, J.S., Stone, C.G., Morgan, S.A., Madu, S.I., Baldini, A., Lindsay, E.A., Biesecker, L.G., Copeland, K.C., Horlick, M.N., Pettigrew, A.L., Zanaria, E. & McCabe, E.R.B. (1995) Diagnosis of X-linked adrenal hypoplasia congenita by mutation analysis of the DAX-1 gene. Journal of American Medical Association, 274, 324-330.
11. Habiby, R.L., Boepple, P., Nachtigall, L., Sluss, P.M., Crowley, W.F. & Jameson, J.L. (1996) Adrenal hypoplasia congenita with hypogonadotropic hypogonadism: evidence that DAX-1 mutations lead to combined hypothalamic and pituitary defects in gonadotropin production. Journal of Clinical Investigation, 98, 1055-1062.
12. Halvorson, L.M., Kaiser, U.B. & Chin, W.W. (1996) Stimulation of luteinizing hormone beta gene promoter activity by the orphan nuclear receptor, steroidogenic factor-1. Journal of Biological Chemistry, 271, 6645-6650.
13. Herman, V., Fagin, J., Gonsky, R., Kovacs, K. & Melmed, S. (1990) Clonal origin of pituitary adenomas. Journal of Clinical Endocrinology & Metabolism, 71, 1427-1433.
14. Ikeda, Y., Luo, X., Abbud, R., Nilson, J.H. & Parker, K.L. (1995) The nuclear receptor steroidogenic factor 1 is essential for the formation of the ventromedial hypothalamic nucleus. Molecular Endocrinology, 9, 478-486.
15. Ikeda, Y., Swain, A., Weber, T.J., Hentges, K.E., Zanaria, E., Lalli, E., Tamai, K.T., Sassone-Corsi, P., Lovell-Badge, R., Camerino, G. & Parker, K.L. (1996) Steroidogenic factor 1 and Dax-1 colocalize in multiple cell lineages: potential links in endocrine development. Molecular Endocrinology, 10, 1261-1272.
16. Ikuyama, S., Ohe, K., Sakai, Y., Nakagaki, H., Fukushima, T., Kato, Y., Morohashi, K.-I., Takayanagi. R. & Nawata, H. (1996) Follicle stimulating hormone-β subunit gene is expressed in parallel with a transcription factor Ad4BP/SF-1 in human pituitary adenomas. Clinical Endocrinology, 45, 187-193.
17. Ingraham, H.A., Lala, D.S., Ikeda, Y., Luo, X., Shen, W.-H., Nachatigal, M.W., Abbud, R., Nilson, J.H. & Parker, K.L. (1994) The nuclear receptor steroidogenic factor 1 acts at multiple levels of the reproductive axis. Genes & Development, 8, 2302-2312.
18. Keri, R.A. & Nilson, J.H. (1996) A steroidogenic factor-1 binding site is required for activity of the luteinizing hormone beta subunit promoter in gonadotropes of transgenic mice. Journal of Biological Chemistry, 271, 10782-10785.
19. Lala, D.S., Syka, P.M., Lazarchik, S.B., Mangelsdorf, D.J., Parker, K.L. & Heyman, R.A. (1997) Activation of the orphan nuclear receptor steroidogenic factor 1 by oxysterols. Proceedings of National Academy of Science U.S.A., 94, 4895-4900.
20. Muscatelli, F., Storm, T.M., Walker, A.P., Zanaria, E., Récan, D., Meindl, A., Bardoni, B., Guioli, S., Zehetner, G., Rabl, W., Schwarz, H.P., Kaplan, J.-C., Camerino, G., Meitinger, T. & Monaco, A.P. (1994) Mutations in the DAX-1 gene give rise to both X-linked adrenal hypoplasia congenita and hypogonadotropic hypogonadism. Nature, 372, 672-676.
21. Pellegrini, I., Barlier, A., Gunz, G., Figorella-Brunger, D., Enjalbert, A., Grisoli, F. & Jaquet, P. (1994) Pit-1 gene expression in the human pituitary and pituitary adenomas. Journal of Clinical Endocrinology & Metabolism, 79, 189-196.
22. Swain, A., Zanaria, E., Hacker, A., Lovell-Badge, R. & Camerino, G. (1996) Mouse DAX-1 expression is consistent with a role in sex determination as well as in adrenal and hypothalamus function. Nature Genetics, 12, 404-409.
23. Therrien, M. & Drouin, J. (1993) Cell-specific helix-loop-helix factor required for pituitary expression of the pro-opiomelanocortin gene. Molecular and Cellular Biology, 13, 2342-2353.
24. Vilain, E., Guo, W., Zhang, Y.-H. & McCabe, E.R.B. (1997) DAX1 gene expression upregulated by steroidogenic factor 1 in an adrenocortical carcinoma cell line. Biochemical and Molecular Medicine, 61, 1-8.
25. Voss, J.W. & Rosenfeld, M.G. (1992) Anterior pituitary development: short tales from dwarf mice. Cell, 70, 527-530.
26. Yamada, S., Takahashi, M., Hara, M., Hattori, A., Sano, T., Ozawa, Y., Shishiba, Y., Hirata, K. & Usui, M. (1996) Pit-1 gene expression in human piluitary adenomas using reverse transcription polymerase chain reaction method. Clinical Endocrinology, 45, 263-272.
27. Yanase, T., Takayanagi, R., Oba, K., Nishi, Y., Ohe. K. & Nawata, H. (1996) New mutation of DAX-1 gene in two Japanese patients with X-linked adrenal hypoplasia congenita and hypogonadotropic hypogonadism. Journal of Clinical Emdocrinology & Metabolism, 81, 530-535, 1996.
28. Zanaria, E., Museatelli, F., Bardoni, B., Strom, T.M., Guioli, S., Guo, W., Lalli, E., Moser, C., Walker, A.P., McCabe, E.R.B., Meitinger, T., Monaco, A.P., Sassone-Corsi, P. & Camerino, G. (1994) An unusual member of the nuclear hormone receptor superfamily responsible for X-linked adrenal hypoplasia congenita. Nature, 372, 635-641.