The mitogen-activated protein kinase pathway contributes to vanadate toxicity in vascular smooth muscle cells

Molecular and Cellular Biochemistry

Volumn 183, Issue 1-2, 1998, Pages 97-103

  Daum, Günter ^a   Levkau, Bodo ^b   Chamberlain, Nancy L ^a   Wang, Yunxia ^a   Clowes, Alexander W ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

Author keywords

MAPK; MAPKK; PD098059; PDGF BB; Vanadate

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; DNA; MITOGEN ACTIVATED PROTEIN KINASE; PLATELET DERIVED GROWTH FACTOR BB; PROTEIN KINASE INHIBITOR; VANADIC ACID;

ANIMAL CELL; ARTICLE; BABOON; CONTROLLED STUDY; CYTOTOXICITY; DNA SYNTHESIS; DNA SYNTHESIS INHIBITION; NONHUMAN; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE;

ANIMALS; AORTA; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CELL DIVISION; CELLS, CULTURED; DNA; ENZYME ACTIVATION; FLAVONOIDS; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MITOGEN-ACTIVATED PROTEIN KINASES; MUSCLE, SMOOTH, VASCULAR; PAPIO; PLATELET-DERIVED GROWTH FACTOR; PROTEIN KINASES; SIGNAL TRANSDUCTION; VANADATES;

ANIMALIA; PAPIO HAMADRYAS;

EID: 0031777895     PISSN: 03008177     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1006820214072     Document Type: Article

References (35)

1. Shechter Y: Insulin-mimetic effects of vanadate. Possible implications for future treatment of diabetes. Diabetes 39: 1-5, 1990
2. Heyliger CE, Tahiliani AG, McNeill JH: Effect of vanadate on elevated blood glucose and depressed cardiac performance of diabetic rats. Science 227: 1474-1477, 1985
3. Domingo JL, Gomez M, Sanchez DJ, Llobet JM, Keen CL: Toxicology of vanadium compounds in diabetic rats: The action of chelating agents on vanadium accumulation. Mol Cell Biochem 153: 233-240, 1995
4. Cruz TF, Morgan A, Min W: In vitro and in vivo antineoplastic effects of orthovanadate. Mol Cell Biochem 153: 161-166, 1995
5. Maher PA: Stimulation of endothelial cell proliferation by vanadate is specific for microvascular endothelial cells. J Cell Physiol 151: 549-554, 1992
6. Chen Y, Chan TM: Orthovanadate and 2,3-dimethoxy-1,4-naphthoquinone augment growth factor-induced cell proliferation and c-fos gene expression in 3T3-L1 cells. Arch Biochem Biophys 305: 9-16, 1993
7. Cortizo AM, Etcheverry SB: Vanadium derivatives act as growth factor-mimetic compounds upon differentiation and proliferation of osteoblast-like UMR 106 cells. Mol Cell Biochem 145: 97-102, 1995
8. Wenzel UO, Fouqueray B, Biswas P, Grandaliano G, Choudhury GG, Abboud HE: Activation of mesangial cells by the phosphatase inhibitor vanadate. Potential implications for diabetic nephropathy. J Clin Invest 95: 1244-1252, 1995
9. Swarup G, Cohen S, Garbers DL: Inhibition of membrane phosphotyrosyl-protein phosphatase activity by vanadate. Biochem Biophys Res Commun 107: 1104-1109, 1982
10. Nguyen TT, Scimeca JC, Filloux C, Peraldi P, Carpentier JL, Van Obberghen E: Co-regulation of the mitogen-activated protein kinase, extracellular signal-regulated kinase 1, and the 90 kDa ribosomal S6 kinase in PC12 cells. Distinct effects of the neurotrophic factor, nerve growth factor, and the mitogenic factor, epidermal growth factor. J Biol Chem 268: 9803-9810, 1993
11. D'Onofrio F, Le MQ, Chiasson JL, Srivastava AK: Activation of mitogen activated protein (MAP) kinases by vanadate is independent of insulin receptor autophosphorylation. FEBS Lett 340: 269-275, 1994
12. Whitmarsh AJ, Davis RJ: Transcription factor AP-1 regulation by mitogen-activated protein kinase signal transduction pathways. J Mol Med 74: 589-607, 1996
13. Anderson NG, Maller JL, Tonks NK, Sturgill TW: Requirement for integration of signals from two distinct phosphorylation pathways for activation of MAP kinase. Nature 343: 651-653, 1990
14. Davis RJ: The mitogen-activated protein kinase signal transduction pathway. J Biol Chem 268: 14553-14556, 1993
15. Seger R, Krebs EG: The MAPK signalling cascade. FASEB J 9: 726-735, 1995
16. Alessi DR, Saito Y, Campbell DG, Cohen P, Sithanandam G, Rapp U, Ashworth A, Marshall CJ, Cowley S: Identification of the sites in MAP kinase kinase-1 phosphorylated by p74raf-1. Embo J 13: 1610-1619, 1994
17. Zheng CF, Guan KL: Activation of MEK family kinases requires phosphorylation of two conserved Ser/Thr residues. Embo J 13: 1123-1131, 1994
18. Daum G, Eisenmann Tappe I, Fries HW, Troppmair J, Rapp UR: The ins and outs of Raf kinases. Trends Biochem Sci 19: 474-480, 1994
19. Dudley DT, Pang L, Decker SJ, Bridges AJ, Saltiel AR: A synthetic inhibitor of the mitogen-activated protein kinase cascade. Proc Natl Acad Sci USA 92: 7686-7689, 1995
20. Alessi DR, Cuenda A, Cohen P, Dudley DT, Saltiel AR: PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo. J Biol Chem 270: 27489-27494, 1995
21. Sun H, Charles CH, Lau LF, Tonks NK: MKP-1 (3CH134), an immediate early gene product, is a dual specificity phosphatase that dephosphorylates MAP kinase in vivo. Cell 75: 487-493, 1993
22. Deibler GE, Martenson RE, Kies MW: Large scale preparation of myelin basic protein from central nervous tissue of several mammalian species. Prep Biochem 2: 139-165, 1972
23. Robbins DJ, Zhen E, Owaki H, Vanderbilt CA, Ebert D, Geppert TD, Cobb MH: Regulation and properties of extracellular signal-regulated protein kinases 1 and 2 in vitro. J Biol Chem 268: 5097-5106, 1993
24. Ross R, Kariya B: Morphogenesis of vascular smooth muscle cells in atherosclerosis and cell culture. D Bohr (ed). American Physiological Society, Bethesda, MD, USA, 1980
25. Gotoh Y, Nishida E, Yamashita T, Hoshi M, Kawakami M, Sakai H: Microtubule-associated-protein (MAP) kinase activated by nerve growth factor and epidermal growth factor in PC12 cells. Identity with the mitogen-activated MAP kinase of fibroblastic cells. Eur J Biochem 193: 661-669, 1990
26. Kameshita I, Fujisawa H: A sensitive method for detection of calmodulin-dependent protein kinase II activity in sodium dodecyl sulfate-polyacrylamide gel. Anal Biochem 183: 139-143, 1989
27. Laemmli UK: Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227: 680-685, 1970
28. Bradford MM: A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72: 248-254, 1976
29. Daum G, Hedin U, Wang Y, Wang T, Clowes AW: Diverse effects of heparin on mitogen-activated protein kinase-dependent signal transduction in vascular smooth muscle cells. Cire Res 81: 17-23, 1997
30. Edelmann HM, Kuhne C, Petritsch C, Ballou LM: Cell cycle regulation of p70 S6 kinase and p42/p44 mitogen-activated protein kinases in Swiss mouse 3T3 fibroblasts. J Biol Chem 271: 963-971, 1996
31. MAPK are required for fibroblast proliferation. Proc Natl Acad Sci USA 90: 8319-8323, 1993
32. Bennett MR, Evan GI, Schwartz SM: Apoptosis of rat vascular smooth muscle cells is regulated by p53-dependent and -independent pathways. Circ Res 77: 266-273, 1995
33. Vaux DL, Strasser A: The molecular biology of apoptosis. Proc Natl Acad Sci USA 93: 2239-2244, 1996
34. Mansour SJ, Matten WT, Hermann AS, Candia JM, Rong S, Fukasawa K, Vande Woude GF, Ahn NG: Transformation of mammalian cells by constitutively active MAP kinase kinase. Science 265: 966-970, 1994
35. Brunet A, Pages G, Pouysségur J: Constitutively active mutants of MAP kinase kinase (MEK1) induce growth factor-relaxation and oncogenicity when expressed in fibroblasts. Oncogene 9: 3379-3387, 1994