Reengineering immunoglobulin domain interactions by introduction of charged residues

Protein Engineering

Volumn 11, Issue 4, 1998, Pages 303-309

  Raffen, Rosemarie ^a   Stevens, Priscilla Wilkins ^a,b   Boogaard, Connie ^a   Schiffer, Marianne ^a   Stevens, Fred J ^a  

^a ARGONNE NATIONAL LABORATORY   (United States)

^b Northwestern University   (United States)

Author keywords

Dimerization; Electrostatics; Gel filtration chromatography; Immunoglobulin light chain variable domain; Site directed mutagenesis

Indexed keywords

IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN LIGHT CHAIN;

ARTICLE; COMPUTER PROGRAM; COMPUTER SIMULATION; DIMERIZATION; GENETIC ENGINEERING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMMUNOGLOBULIN STRUCTURE; IMMUNOGLOBULIN VARIABLE REGION; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DOMAIN; PROTEIN STABILITY;

EID: 0031776392     PISSN: 02692139     EISSN: None     Source Type: Journal    
DOI: 10.1093/protein/11.4.303     Document Type: Article

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