Pathogenesis of acute ischemic coronary syndromes

Journal of Interventional Cardiology

Volumn 11, Issue 5 I, 1998, Pages 427-435

  Talley, J David ^a,b  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^b UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACUTE HEART INFARCTION; CLINICAL FEATURE; CORONARY ARTERY ATHEROSCLEROSIS; CORONARY ARTERY THROMBOSIS; HEART MUSCLE ISCHEMIA; HUMAN; MORTALITY; PATHOPHYSIOLOGY; PRIORITY JOURNAL; REVIEW; SUDDEN DEATH; THROMBOCYTE ADHESION; THROMBOCYTE AGGREGATION; UNSTABLE ANGINA PECTORIS;

EID: 0031773751     PISSN: 08964327     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1540-8183.1998.tb00145.x     Document Type: Review

References (72)

1. Fuster V, Badimon L, Badimon JJ, et al. The pathogenesis of coronary artery disease and the acute coronary syndromes. N Engl J Med 1992;326:242-250, 310-318.
2. American Heart Association. Heart and Stroke Facts: 1996 Statistical Supplement. Dallas, TX: American Heart Association National Center, 1996.
3. Constantinides P. Plaque fissures in human coronary thrombosis. J Atheroscler Res 1966;6:1-17.
4. Falk E. Unstable angina with fatal outcome: Dynamic coronary thrombosis leading to infarction and/or sudden death. Autopsy evidence at recurrent mural thrombosis with peripheral embolization on culmination in total vascular occlusion. Circulation 1985;71:699-708.
5. Falk E. Morphologic features of unstable atherothrombotic plaques underlying acute coronary syndromes. Am J Cardiol 1989;63:114E-120E.
6. Davies MJ, Thomas A. Thrombosis and acute coronary-artery lesions in sudden cardiac ischemic death. N Engl J Med 1984;310:1137-1140.
7. Davies MJ, Thomas AC. Plaque fissuring - The cause of acute myocardial infarction, sudden ischemic death, and crescendo angina. Br Heart J 1985;53:363-373.
8. Davies MJ, Thomas AC, Knapman PA, et al. Intramyocardial platelet aggregation in patients with unstable angina suffering sudden ischemic cardiac death. Circulation 1986;73:418-427.
9. Davies MJ. A macro and micro view of coronary vascular insult in ischemic heart disease. Circulation 1990;82(Suppl. II):II-38-II-46.
10. Burke AP, Farb A, Malcom GT, et al. Coronary risk factors and plaque morphology in men with coronary disease who died suddenly. N Engl J Med 1997;336:1276-1282.
11. Farb A, Burke AP, Tang AL, et al. Coronary plaque erosion without rupture into a lipid core: A frequent cause of coronary thrombosis in sudden coronary death. Circulation 1996;93:1354-1363.
12. Shah PK. Pathophysiology of plaque rupture and the concept of plaque stabilization. Cardiol Clin 1996;14:17-29.
13. Davies MJ. The composition of coronary-artery plaques. N Engl J Med 1997;336:1312-1314.
14. Shah PK. New insights into the pathogenesis and prevention of acute coronary syndromes. Am J Cardiol 1997;79(Suppl. 12B):17-23.
15. Loree HM, Kamm RD, Stringfellow RG, et al. Effects of fibrous cap thickness on peak circumferential stress in model atherosclerotic vessels. Circ Res 1992;71:850-858.
16. Cheng GC, Loree HM, Kamm RD, et al. Distribution of circumferential stress in ruptured and stable atherosclerotic lesions: A structural analysis with histopathological correlation. Circulation 1993;87:1179-1187.
17. Jonasson L, Holm J, Skalli O, et al. Regional accumulations of T cells, macrophages, and smooth muscle cells in the human atherosclerotic plaque. Arteriosclerosis 1986;6:131-138.
18. Berliner JA, Navab M, Fogelman AM, et al. Atherosclerosis: Basic mechanisms. Oxidation, inflammation and genetics. Circulation 1995;91:2488-2496.
19. Hansson GK, Libby P. The role of the lymphocyte. In: Fuster V, Ross R, Topol EJ, eds. Atherosclerosis and Coronary Artery Disease. Philadelphia: Lippincott-Raven Publishers, 1996, pp. 557-568.
20. Amento EP, Ehsani N, Palmer H, et al. Cytokines and growth factors positively and negatively regulate interstitial collagen gene expression in human vascular smooth muscle cells. Arterioscler Thromb 1991;11:1223-1230.
21. Hansson GK, Jonasson L, Holm J, et al. Gamma-interferon regulates vascular smooth muscle proliferation and Ia antigen expression in vivo and in vitro. Circ Res 1988;63:712-719.
22. Geng YJ, Wu Q, Muszynski M, et al. Apoptosis of vascular smooth muscle cells induced by in vitro stimulation with interferon-γ, tumor necrosis factor-α, and interleukin-1β. Arterioscler Thromb Vasc Biol 1996;16:19-27.
23. Raines EW, Rosenfeld ME, Ross R. The role of macrophages. In: Fuster V, Ross R, Topol EJ, eds. Atherosclerosis and Coronary Artery Disease. Philadelphia: Lippincott-Raven Publishers, 1996, pp. 539-555.
24. Galis ZS, Muszynski M, Sukhova GK, et al. Cytokine-stimulated human vascular smooth muscle cells synthesize a complement of enzymes required for extracellular matrix digestion. Circ Res 1994;75:181-189.
25. Galis ZS, Sukhova GK, Lark MW, et al. Increased expression of matrix metalloproteinases and matrix degrading activity in vulnerable regions of human atherosclerotic plaques. J Clin Invest 1994;94:2493-2503.
26. Galis ZS, Sukhova GK, Libby P. Microscopic localization of active proteases by in situ zymography: Detection of matrix metalloproteinase activity in vascular tissue. FASEB J 1995;9:974-980.
27. Wilcox JN, Smith KM, Schwartz SM, et al. Localization of tissue factor in the normal vessel wall and in the atherosclerotic plaque. Proc Natl Acad Sci U S A 1989;86:2839-2843.
28. Toschi V, Gallo R, Lettino M, et al. Tissue factor modulates the thrombogenicity of human atherosclerotic plaques. Circulation 1997;95:594-599.
29. Coller BS. Platelets in cardiovascular thrombosis and thrombolysis. In: Fozzard HA, Faber E, Jennings RB, et al., eds. The Heart and Cardiovascular System: Scientific Foundations, 2nd ed. New York, NY: Raven Press, 1992, pp. 219-273.
30. Ruggeri ZM. Mechanisms initiating platelet thrombus formation. Thromb Haemost 1997;78:611-616.
31. Savage B, Saldivar E, Ruggeri ZM. Initiation of platelet adhesion by arrest onto fibrinogen or translocation on von Willebrand factor. Cell 1996;84:289-297.
32. Savage B, Ruggeri ZM. Selective recognition of adhesive sites in surface-bound fibrinogen by glycoprotein IIb/IIIa on nonactivated platelets. J Biol Chem 1991;266:11227-11233.
33. Weiss HJ, Turitto VT, Baumgartner HR. Platelet adhesion and thrombus formation on subendothelium in platelets, deficient in glycoproteins IIb-IIIa, Ib, and storage granules. Blood 1986;67:322-330.
34. Lawrence JB, Gralnick HR. Monoclonal antibodies to the glycoprotein IIb-IIIa epitopes involved in adhesive protein binding: Effects on platelet spreading and ultrastructure on human arterial subendothelium. J Lab Clin Med 1987;109:495-503.
35. Savage B, Shattil SJ, Ruggeri ZM. Modulation of platelet function through adhesion receptors: A dual role for glycoprotein IIb-IIIa (integrin alpha IIb beta 3) mediated by fibrinogen and glycoprotein Ib-von Willebrand factor. J Biol Chem 1992;267:11300-11306.
36. Lefkovits J, Plow EF, Topol EJ. Platelet glycoprotein IIb/IIIa receptors in cardiovascular medicine. N Engl J Med 1995;332:1553-1559.
37. Coller BS. Platelet GPIIb/IIIa antagonists: The first anti-integrin receptor therapeutics. J Clin Invest 1997;99:1467-1471.
38. Phillips DR, Charo IF, Parise LV, et al. The platelet membrane glycoprotein IIb-IIIa complex. Blood 1988;71:831-843.
39. Coller BS, Seligsohn U, Peretz H, et al. Glanzmann thrombasthenia: New insights from an historical perspective. Semin Hematol 1994;31:301-311.
40. Hynes RO. Integrins: A family of cell surface receptors. Cell 1987;48:549-554.
41. Ikeda Y, Handa M, Kawano K, et al. The role of von Willebrand factor and fibrinogen in platelet aggregation under varying shear stress. J Clin Invest 1991;87:1234-1240.
42. Ginsberg MH, Du X, Plow EF. Inside-out integrin signalling. Curr Opin Cell Biol 1992;4:766-771.
43. Fox JE. Regulation of platelet function by the cytoskeleton. Adv Exp Med Biol 1993;344:175-185.
44. Mailhac A, Badimon JJ, Fallon JT, et al. Effect of an eccentric severe stenosis on fibrin(ogen) deposition on severely damaged vessel wall in arterial thrombosis. Relative contribution of fibrin(ogen) and platelets. Circulation 1994;90:988-996.
45. Mizuno K, Satomura K, Miyamoto A, et al. Angioscopic evaluation of coronary artery thrombi in acute coronary syndromes. N Engl J Med 1992;326:287-291.
46. Hamsten A, de Faire U, Walldius G, et al. Plasminogen activator inhibitor in plasma: Risk factor for recurrent myocardial infarction. Lancet 1987;2:3-9.
47. Merlini PA, Bauer KA, Oltrona L, et al. Persistent activation of coagulation mechanism in unstable angina and myocardial infarction. Circulation 1994;90:61-68.
48. Milner PC, Martin JF. Shortened bleeding time in acute myocardial infarction and its relation to platelet mass. Br Med J (Clin Res Ed) 1985;290:1767-1770.
49. Alderman MH, Madhavan S, Ooi WL, et al. Association of the renin-sodium profile with the risk of myocardial infarction in patients with hypertension. N Engl J Med 1991;324:1098-1104.
50. Heinrich J, Balleisen L, Schulte H, et al. Fibrinogen and factor VII in the prediction of coronary risk. Results from the PROCAM study in healthy men. [Published erratum appears in Arterioscler Thromb 1994;14:1392.] Arterioscler Thromb 1994;14:54-59.
51. Larsson PT, Wallèn NH, Hjemdahl P. Norepinephrine-induced human platelet activation in vivo is only partly counter-acted by aspirin. Circulation 1994;89:1951-1957.
52. Miller GJ, Bauer KA, Barzegar S, et al. Increased activation of the haemostatic system in men at high risk of fatal coronary heart disease. Thromb Haemost 1996;75:767-771.
53. Badimon L, Badimon JJ. Mechanisms of arterial thrombosis in nonparallel streamlines: Platelet thrombi grow on the apex of stenotic severely injured vessel wall. Experimental study in the pig model. J Clin Invest 1989;84:1134-1144.
54. Lee RT, Kamm RD. Vascular mechanics for the cardiologist. J Am Coll Cardiol 1994;23:1289-1295.
55. Fuster V. Mechanisms leading to myocardial infarction: Insights from studies of vascular biology. Circulation 1994;90: 2126-2146.
56. Cannon CP, McCabe CH, Stone PH, et al. The electrocardiogram predicts one-year outcome of patients with unstable angina and non-Q wave myocardial infarction: Results of the TIMI III registry ECG ancillary study. J Am Coll Cardiol 1997;30:133-140.
57. Ambrose JA, Weinrauch M. Thrombosis in ischemic heart disease. Arch Intern Med 1996;156:1382-1394.
58. Antman EM, Tanasijevic MJ, Thompson B, et al. Cardiac-specific troponin I levels to predict the risk of mortality in patients with acute coronary syndromes. N Engl J Med 1996;335: 1342-1349.
59. Lindahl B, Venge P, Wallentin L, et al. Relation between troponin T and the risk of subsequent cardiac events in unstable coronary artery disease. Circulation 1996;93:1651-1657.
60. McClellan JR. Unstable angina: Prognosis, noninvasive risk assessment, and strategies for management. Clin Cardiol 1994;17:229-238.
61. The TIMI IIIB Investigators. Effects of tissue plasminogen activator and a comparison of early invasive and conservative strategies in unstable angina and non-Q-wave myocardial infarction: Results of the TIMI IIIB Trial. Circulation 1994;89:1545-1556.
62. The Global Use of Strategies to Open Occluded Coronary Arteries (GUSTO) IIb Investigators. A comparison of recombinant hirudin with heparin for the treatment of acute coronary syndromes. N Engl J Med 1996;335:775-782.
63. Klein W, Buchwald A, Hillis SE, et al. Comparison of low-molecular-weight heparin with unfractionated heparin acutely and with placebo for 6 weeks in the management of unstable coronary artery disease: Fragmin in Unstable Coronary Artery Disease Study (FRIC). Circulation 1997;96:61-68.
64. Fragmin during Instability in Coronary Artery Disease (FRISC) study group. Low-molecular-weight heparin during instability in coronary artery disease. Lancet 1996;347: 561-568.
65. Braunwald E, Mark DB, Jones RH, et al. Unstable angina: Diagnosis and management. Clinical Practice Guideline, Number 10. Rockville, MD: U.S. Dept. of Health and Human Services, 1994, Pub. 94-0602.
66. DeWood MA, Stifter WF, Simpson CS, et al. Coronary arteriographic findings soon after non-Q-wave myocardial infarction. N Engl J Med 1986;315:417-423.
67. Weaver WD, Simes RJ, Betriu A, et al. Comparison of primary coronary angioplasty and intravenous thrombolytic therapy for acute myocardial infarction. JAMA 1997;278:2093-2098.
68. Jha P, DeBoer D, Sykora K, et al. Characteristics and mortality outcomes of thrombolysis trial participants and nonparticipants: A population-based comparison. J Am Coll Cardiol 1996;27:1335-1342.
69. Mehta D, Curwin J, Gomes JA, et al. Sudden death in coronary artery disease. Acute ischemia versus myocardial substrate. Circulation 1997;96:3215-3223.
70. Cobb LA, Werner JA, Trobaugh GB. Sudden cardiac death: I. A decade's experience with out-of-hospital resuscitation. Mod Concepts Cardiovasc Dis 1980;49:31-36.
71. Davies MJ, Bland JM, Hangartner JR, et al. Factors influencing the presence or absence of acute coronary artery thrombi in sudden ischaemic death. Eur Heart J 1989;10:203-208.
72. Zehender M, Faber T, Meinertz T, et al. Clinical evidence for the fatal interaction of ventricular tachyarrhythmias, myocardial ischemia and sudden cardiac death. Herz 1995;20: 187-199.