The isoprostanes: Unique bioactive products of lipid peroxidation: An overview

Journal of Biomedical Science

Volumn 5, Issue 6, 1998, Pages 415-420

  Liu, Tsan Zon ^a   Stern, Arnold ^b,d   Morrow, Jason D ^c  

^a YUAN'S GENERAL HOSPITAL   (Taiwan)

^b NEW YORK UNIVERSITY   (United States)

^c VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Gas chromatography; Human disease; Isoprostanes; Lipid peroxidation; Mass spectrometry; Oxidative stress

Indexed keywords

ARACHIDONIC ACID; FREE RADICAL; ISOPROSTANE; LIPID; PROSTAGLANDIN F2;

ACCURACY; ARACHIDONIC ACID METABOLISM; CIGARETTE SMOKING; GAS CHROMATOGRAPHY; HEPATORENAL SYNDROME; HUMAN; LIPID PEROXIDATION; MASS SPECTROMETRY; OXIDATIVE STRESS; PRIORITY JOURNAL; PROSTAGLANDIN METABOLISM; REVIEW; SCLERODERMA;

SCLERODERMA;

EID: 0031773099     PISSN: 10217770     EISSN: 14230127     Source Type: Journal    
DOI: 10.1007/BF02255929     Document Type: Review

References (27)

1. 2-isoprostanes. J Nutr 124: 810-816;1994.
2. Awad JA, Roberts LJ, Burk RF, Morrow JD. Isoprostanes - Prostaglandin-like compounds formed in vivo independently of cyctooxygenase. Gastroenterol Clin North Am 25:409-427; 1996.
3. 2α, in rabbit lung in situ. Am J Physiol 263:H660-H663;1992.
4. Burk RF, Hill KE, Awad JA, Morrow JD, Kato T, Cockell KA, Lyons PR. Pathogenesis of diquat-induced liver necrosis in selenium-deficient rats: Assessment of the roles of lipid peroxidation and selenoprotein P. Hepatology 21:561-569;1995.
5. Church DF, Pryor WA. Free-radical chemistry of cigarette smoke and its toxicological complications. Environ Health Perspect 64:111-126; 1985.
6. 2-isoprostane receptors on rat vascular smooth muscle. Am J Physiol 264; C1619-C1624;1993.
7. 2. Am J Physiol 272:F477-F483;1997.
8. Halliwell B, Grootveld M. The measurement of free radical reactions in humans. FEBS Lett 213-9-14;1987.
9. 2α in isolated perfused rat lung. J Appl Physiol 74:460-465;1993.
10. Mason RP, Fischer V. Free radicals of acetaminophen: Their subsequent reactions and toxicological significance. Fed Proc 45:2493-2499;1986.
11. Moore K, Wenden J, Frazer M, Karani J, Williams R, Badr KF. Plasma endothelin immuno-reactrvity in liver disease and the hepatorenal syndrome. N Engl J Med 327:1774-1778; 1992.
12. 2-like compounds are produced in vivo in humans by a non-cyclooxygenase. free radicalcatalyzed mechanism. Proc Natl Acad Sci USA 87:9383-9397;1990.
13. Morrow JD, Harris TM, Roberts LJ. Noncyclooxygenase oxidative formation of a series of novel prostaglandim: analytical ramifications for measurement of eicosanoids. Anal Biochem 184:1-10;1990.
14. 2-isoprostanes) are formed in situ on phospholipids. Proc Natl Acad Sci USA 89: 10721-10725;1992.
15. Morrow JD; Awad JA, Kato T, Takahashi K, Badr KF, Roberts LJ, Burk RF. Formation of novel non-cyclooxygenase-denved prostanoids (Fi-isoprostanes) in carbon tetrachloride hepatotoxicity. J Clin Invest 90:2502-2507;1992.
16. 2-isoprostanes) in the hepatorenal syndrome. J Lipid Med 6:417-420;1993.
17. 2-Isoprostanes produced by noncyclooxygenase free radical-catalyzed mechanism. Methods Enzymol 233:163-174;1994.
18. 2α, is formed in vivo. Biochim Biophys Acta 1210:244-248;1994.
19. Morrow JD, Minton TA, Mukundan CR, Campbell MD, Zacken WE, Daniel VC, Badr KF, Blair IA, Roberts LJ. Free radical-induced generation of isoprostanes in vivo: Evidence for the formation of D-ring and E-ring isoprostanes. J Biol Chem 269:4317-4326;1994.
20. 2-isoprostanes) in smokers: Smoking as a cause of oxidative damage. N Engl J Med 332:1198-1203;1995.
21. Morrow JD, Awad JA, Wu A, Zackert WE, Daniel VC, Roberts LJ. Nonenzymatic free radical-catalyzed generation of thromboxanelike compounds (isothromboxanes) in vivo. J Biol Chem 271:23185-23190;1996.
22. Morrow JD, Roberts LJ, The isoprostanes: Unique bioactive products of lipid peroxidation. Prog Lipid Res 36:1-21;1997.
23. Murrell DF. A radical proposal for the pathogenesis of scleroderma. J Am Acad Dermatol 28:78-85;1993.
24. Reilly M, Deianty N, Lawson JA, Fitzgerald GA. Modulation of oxidant stress in vivo in chronic cigarette smokers. Circulation 94:19-25;1996.
25. Schelling JR, Linas SL. Hepatorenal syndrome. Semin Nephrol 10:565-570;1990.
26. Stein CM, Tanner SB, Awad JA, Roberts LJ, Morrow JD. Evidence of free radical-mediated injury (isoprostane overproduction) in scleroderma. Arthritis Rheum 39:1146-1150;1996.
27. 2α, in the rat - Evidence for interaction with thromboxane A; receptors. J Clin Invest 90:136-141;1992.