The nondigestible fat sucrose polyester does not stimulate gallbladder emptying in humans

American Journal of Clinical Nutrition

Volumn 68, Issue 6, 1998, Pages 1272-1275

  Maas, Monique I M ^b   Hopman, Wim P M ^b   Katan, Martijn B ^b   Jansen, Jan B M J ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b NONE

Author keywords

Cholecystokinin; Digestible fat; Gallbladder motility; Gallstones; Obesity; Sucrose polyester; Very low fat diets; Weight loss

Indexed keywords

CHOLECYSTOKININ; FAT; SODIUM CHLORIDE; SUCROSE POLYESTER;

ADULT; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DIGESTION; FAT INTAKE; FEMALE; GALLBLADDER EMPTYING; GALLBLADDER MOTILITY; HUMAN; HUMAN EXPERIMENT; LOW FAT DIET; MALE; NORMAL HUMAN; TEST MEAL;

EID: 0031772903     PISSN: 00029165     EISSN: None     Source Type: Journal    
DOI: 10.1093/ajcn/68.6.1272     Document Type: Article

References (41)

1. Hopman WPM, Jansen JBMJ, Lamers CBHW. Comparative study of the effect of fat, protein and starch on plasma cholecystokinin in man. Scand J Gastroenterol 1985;20:843-7.
2. Hopman WP, Jansen JB, Rosenbusch G, Lamers CB. Effect of equimolar amounts of long-chain triglycerides and medium-chain triglycerides on plasma cholecystokinin and gallbladder contraction. Am J Clin Nutr 1984;39:356-9.
3. Hopman WPM, Kerstens PJSM, Jansen JBMJ, Rosenbusch G, Lamers CBHW. Effect of graded physiological doses of cholecystokinin on gallbladder contraction measured by ultrasonography: determination of threshold, dose-response relationship and comparison with intraduodenal bilirubin output. Gastroenterology 1985; 89:1242-7.
4. Kerstens PJSM, Lamers CBHW, Jansen JBMJ, de Jong AJL, Hessels M, Hafkenscheid JCM. Physiological plasma concentrations of cholecystokinin stimulate pancreatic enzyme secretion and gallbladder contraction in man. Life Sci 1985;36:565-9.
5. Liddle RA, Gertz BJ, Kanayama S, et al. Effects of a novel cholecystokinin (CCK) antagonist, MK-329, on gallbladder contraction and gastric emptying in humans. Implication for the physiology of CCK. J Clin Invest 1989;84:1220-5.
6. Busch N, Matern S. Current concepts in cholesterol gallstone pathogenesis. Eur J Clin Invest 1991;21:453-60.
7. Hay DW, Carey MC. Pathophysiology and pathogenesis of cholesterol gallstone formation. Semin Liver Dis 1990;10:159-70.
8. Paumgartner G, Sauerbruch T. Gallstones: pathogenesis. Lancet 1991;338:1117-21.
9. Maclure KM, Hayes KC, Colditz GA, Stampfer MJ, Speizer FE, Willett WC. Weight, diet, and the risk of symptomatic gallstones in middle aged women. N Engl J Med 1989;321:563-9.
10. Everhart JE. Contributions of obesity and weight loss to gallstone disease. Ann Intern Med 1993;119:1029-35.
11. Broomfield PH, Chopra R, Sheinbaum RC, et al. Effects of ursodeoxycholic acid and aspirin on the formation of lithogenic bile and gallstones during loss of weight. N Engl J Med 1988;319: 1567-72.
12. Liddle RA, Goldstein RB, Saxton J. Gallstone formation during weight reduction dieting. Arch Intern Med 1989;149:1750-3.
13. Stone BG, Ansel HJ, Peterson FJ, Gebhard RL. Gallbladder emptying stimuli in obese and normal weight subjects. Hepatology 1992;15:795-8.
14. Marzio L, Capone F, Neri M, Mezzetti A, De-Angelis C, Cuccurullo F. Gallbladder kinetics in obese patients. Effect of a regular meal and low calorie meal. Dig Dis Sci 1988;33:4-9.
15. Mattson FH, Volpenheim RA. Hydrolysis of fully esterified alcohols containing from one to eight hydroxyl groups by the lipolytic enzymes of rat pancreatic juice. J Lipid Res 1972;13:325-8.
16. Mattson FH, Nolen GA. Absorbability by rats of compounds containing from one to eight ester groups. J Nutr 1972;102:1171-5.
17. Fallat RW, Glucck CJ, Lutmer R, Mattson FH. Short term study of sucrose polyester a nonabsorbable fat-like material as a dietary agent for lowering plasma cholesterol. Am J Clin Nutr 1976;29: 1204-15.
18. Everson GT, Braverman DZ, Johnson ML, Kern F Jr. A critical evaluation of real-time ultrasonography for the study of gallbladder volume and contraction. Gastroenterology 1980;79:40-6.
19. Hopman WPM, Brouwer WFM, Rosenbusch G, Jansen JMBJ, Lamers CBHW. A computerized method for rapid quantification of gallbladder volume from real-time sonograms. Radiology 1985; 154:236-7.
20. Jansen JBMJ, Lamers CBHW. Radioimmunoassay of cholecystokinin in human tissue and plasma. Clin Chim Acta 1983;131: 305-16.
21. Armitage P, Berry G. Statistical methods in medical research. 3rd ed. London: Blackwell Science, 1996.
22. Hommel G. Multiple test procedures for arbitrary dependence structures. Metrika 1986;33:321-36.
23. Froehlich F, Gonvers JJ, Fried M. Role of nutrient fat and cholecystokinin in regulation of gallbladder emptying in man. Dig Dis Sci 1995;40:529-33.
24. Fullarton GM, Meek AC, Gray HW, Bessent RG. Gallbladder emptying following cholecystokinin and fatty meal in normal subjects. Hepatogastroenterology 1990;37(suppl):45-8.
25. Masclee AAM, Hopman WPM, Corstens FHM, Rosenbusch G, Jansen JBMJ, Lamers CBHW. Simultaneous measurements of gallbladder emptying with cholescintigraphy and US during infusion of physiological doses of cholecystokinin: a comparison. Radiology 1989;173:407-10.
26. Cortot A, Phillips SF, Malagelada JR. Parallel gastric emptying of nonhydrolyzable fat and water after a solid-liquid meal in humans. Gastroenterology 1982;82:877-81.
27. Aggarwal AM, Camilleri M, Phillips SF, Schlagheck TG, Brown ML, Thomforde GM. Olestra, a nondigestible, nonabsorbable fat. Effects on gastrointestinal and colonic transit. Dig Dis Sci 1993;38:1009-14.
28. Maas MI, Hopman WP, van der Wijk T, Katan MB, Jansen JB. Sucrose polyester does not inhibit gastric acid secretion or stimulate cholecystokinin release in men. Am J Clin Nutr 1997;65:761-5.
29. Masclee AA, Jansen JB, Corstens FH, Lamers CB. Reversible gallbladder dysfunction in severe pancreatic insufficiency. Gut 1989;30:866-72.
30. Jansen JBMJ, Jebbink MCW, Mulders HJA, Lamers CBHW. Effect of pancreatic enzyme supplementation on postprandial plasma cholecystokinin secretion in patients with pancreatic insufficiency. Regul Pept 1989;25:333-42.
31. Jansen JBMJ, Hopman WPM, Rosenbusch G, Lamers CBHW. Plasma cholecystokinin and gallbladder responses to intraduodenal fat and intravenous cholecystokinin in patients with coeliac disease. Eur J Gastroenterol Hepatol 1992;4:349-53.
32. Hopman WPM, Rosenbuch G, Hectors MPC, Jansen JMBJ. Effect of predigested fat on intestinal stimulation of plasma cholecystokinin and gallbladder motility in coeliac disease. Gut 1995;36: 17-21.
33. Fried M, Schwizer W, Froehlich F, et al. Role of lipase in the regulation of upper gastrointestinal functions in man. Studies with THL. A new highly specific lipase inhibitor. Gastroenterology 1992;100: A272 (abstr).
34. Schwizer W, Borovicka J, Gutmann G, Güzelhan C, Hartmann D, Fried M. Role of lipase in the regulation of gastric acid secretion and gastric emptying in humans: a study with orlistat, a highly specific lipase inhibitor. Gastroenterology 1995;108:A686 (abstr).
35. Kelly SM, Hunter JO. The effect of a non-absorbable fat substitute, sucrose polyester, on gastrointestnial function. Aliment Pharmacol Ther 1996;10:715-20.
36. Witteman BJM, Jebbink MCW, Hopman WPM, Masclee AAM, Lamers CBHW, Jansen JBMJ. Gallbladder responses to modified sham feeding: effects of the composition of a meal. J Hepatol 1993;19:465-9.
37. Thimister PWL, Hopman WPM, Sloots CEJ, et al. Role of intraduodenal proteases in plasma cholecystokinin and pancreaticobiliary responses to protein and amino acids. Gastroenterology 1996;110:567-75.
38. Roslyn JJ, Pitt HA, Man LL, Ament ME, DenBesten L. Gallbladder disease in patients on long-term parenteral nutrition. Gastroenterology 1983;84:148-54.
39. Cano N, Cicero F, Ranieri F, Martin J, DiConstanzo J. Ultrasonographic study of gallbladder motility during total parenteral nutrition. Gastroenterology 1986;91:313-7.
40. Messing B, Bories C, Kunstlinger F, Bernier J. Does total parenteral nutrition induce gallbladder sludge formation and lithiasis? Gastroenterology 1983;84:1012-9.
41. Gebhard RL, Prigge WF, Ansel HL, et al. The role of gallbladder emptying in gallstone formation during diet-induced rapid weight loss. Hepatology 1996;24:544-8.