Two distinct signaling pathways mediate DIF induction of prestalk gene expression in Dictyostelium

Experimental Cell Research

Volumn 245, Issue 1, 1998, Pages 179-185

  Verkerke van Wijk, Irene ^a   Brandt, Raymond ^a   Bosman, Laurens ^a   Schaap, Pauline ^a,b  

^a LEIDEN UNIVERSITY   (Netherlands)

^b LEIDEN UNIVERSITY   (Netherlands)

Author keywords

Ca2+ signaling; Dictyostelium; Differentiation inducing factor; Programmed cell death; Stalk cell differentiation

Indexed keywords

ARTICLE; CONTROLLED STUDY; DICTYOSTELIUM; GENE EXPRESSION REGULATION; GENE INDUCTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION;

DICTYOSTELIUM; EUKARYOTA;

EID: 0031771555     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1006/excr.1998.4248     Document Type: Article

References (40)

1. Kay, R. R., and Jermyn, K. A. (1983). A possible morphogen controlling differentiation in Dictyostelium. Nature 303, 242-244.
2. Williams, J. G., Ceccarelli, A., McRobbie, S., Mahbubani, H., Kay, R. R., Early, A., Berks, M., and Jermyn, K. A. (1987). Direct induction of Dictyostelium prestalk gene expression by DIF provides evidence that DIF is a morphogen. Cell 49, 185-192.
3. Firtel, R. A. Integration of signaling information in controlling cell-fate decisions in Dictyostelium. Genes Dev. 9, 1427-1444.
4. Kawata, T., Shevchenko, A., Fukuzawa, M., Jermyn, K. A., Totty, N. F., Zhukovskaya, N. V., Sterling, A. E., Mann, M., and Williams, J. G. (1997). SH2 signaling in a lower eukaryote: A STAT protein that regulates stalk cell differentiation in Dictyostelium. Cell 89, 909-916.
5. Darnell, J. E., Kerr, I. M., and Stark, G. R. (1995). Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science 264, 1415-1420.
6. Maeda, Y., and Maeda, M. (1973). The calcium content of the cellular slime mold, Dictyostelium discoideum, during development and differentiation. Exp. Cell Res. 82, 125-130.
7. Tirlapur, U. K., Gross, J. G., and Nanjundiah, V. (1991). Spatial variation of sequestered calcium in the multicellular stage of Dictyostelium discoideum as assayed by chlortetracycline fluorescence. Differentiation 48, 137-146.
8. Saran, S., Nakao, H., Tasaka, M., Iida, H., Tsuji, F. I., Nanjundiah, V., and Takeuchi, I. (1994). Intracellular free calcium level and its response to cAMP stimulation in developing Dictyostelium cells transformed with jellyfish apoaequorin cDNA. FEBS Lett. 337, 43-47.
9. Cubitt, A. B., Firtel, R. A., Fischer, G., Jaffe, L. F., and Miller, A. L. (1995). Patterns of free calcium in multicellular stages of Dictyostelium expressing jellyfish apoaequorin. Development 121, 2291-2301.
10. 2+ levels mediates stalk gene induction by differentiation inducing factor in Dictyostelium. EMBO J. 15, 5177-5183.
11. Kaiser, N., and Edelman, I. S. (1977). Calcium dependence of glucocorticoid-induced lymphocytolysis. Proc. Natl. Acad. Sci. USA 74, 638-642.
12. 2+ concentration. Arch. Biochem. Biophys. 269, 365-370.
13. 2+ homeostasis in mouse lymphoma cells. Mol. Endocrinol. 7, 686-693.
14. 2+ and H+ concentrations determine cell fate in Dictyostelium discoideum. FASEB J. 8, 869-874.
15. Ludérus, M. E. E., Van der Most, R. G., Otte, A. P., and Van Driel, R. (1989). A protein kinase C-related enzyme activity in Dictyostelium discoideum. FEBS Lett. 253, 71-75.
16. Goldhagen, H., and Clarke, M. (1986). Identification of the single gene for calmodulin in Dictyostelium discoideum. Mol. Cell. Biol. 6, 1851-1854.
17. Damman, H., Hellstern, S., Husain, Q., and Mutzel, R. (1996). Primary structure, expression and developmental regulation of a Dictyostelium calcineurin A homologue. Eur. J. Biochem. 238, 391-399.
18. Abe, F., and Maeda, Y. (1995). Specific expression of a gene encoding a novel calcium-binding protein, CAF-1, during transition of Dictyostelium cells from growth to differentiation. Dev. Growth Differ. 37, 39-48.
19. 2+-binding protein from Dictyostelium discoideum. FEBS Lett. 362, 342-346.
20. André, B., Noegel, A. A., and Schleicher, M. (1996). Dictyostelium discoideum contains a family of calmodulin-related EF-hand proteins that are developmentally regulated. FEBS Lett. 382, 198-202.
21. Horn, F., and Gross, J. (1996). A role for calcineurin in Dictyostelium development. Differentiation 60, 269-275.
22. Watts, D. J., and Ashworth, J. M. (1970). Growth of myxamoebae of the cellular slime mould Dictyostelium discoideum in axenic culture. Biochem. J. 119, 171-174.
23. Pears, C. J., and Williams, J. G. (1987). Identification of a DNA sequence element required for efficient expression of a developmentally regulated and cAMP-inducible gene of Dictyostelium discoideum. EMBO J. 6, 195-200.
24. Datta, S., and Firtel, R. A. (1988). An 80-bp cis-acting regulatory region controls cAMP and development regulation of a prestalk gene in Dictyostelium. Genes Dev. 2, 294-304.
25. Dingermann, T., Reindl, N., Werner, H., Hildebrandt, M., Nellen, W., Harwood, A., Williams, J., and Nerke, K. (1989). Optimization and in situ detection of Escherichia coli β-galactosidase gene expression in Dictyostelium discoideum. J. Cell Biol. 85, 353-362.
26. Ceccarelli, A., Mahbubani, H., and Williams, J. G. (1991). Positively and negatively acting signals regulating stalk cell and anterior-like cell differentiation in Dictyostelium. Cell 65, 983-989.
27. Faure, M., Franke, J., Hall, A. L., Podgorski, G. J., and Kessin, R. H. (1990). The cyclic nucleotide phosphodiesterase gene of Dictyostelium discoideum contains three promoters specific for growth, aggregation, and late development. Mol. Cell. Biol. 10, 1921-1930.
28. Nellen, W., Datta, S., Reymond, C., Sivertsen, A., Mann, S., Crowley, T., and Firtel, R. A. (1987). Molecular Biology in Dictyostelium: Tools and applications. In "Methods in Cell Biology" (J. A. Spudich, Ed.), pp. 67-100, Academic Press, London.
29. Jermyn, K. A., Berks, M., Kay, R. R., and Williams, J. G. (1987). Two distinct classes of prestalk-enriched mRNA sequences in Dictyostelium discoideum. Development 100, 745-755.
30. Berks, M., and Kay, R. R. (1990). Combinatorial control of cell differentiation by cAMP and DIF-1 during development of Dictyostelium discoideum. Development 11, 977-984.
31. So, J.-S., and Weeks, G. (1992). The effects of presumptive morphogens on prestalk and prespore cell gene expression in monolayers of Dictyostelium discoideum. Differentiation 51, 73-78.
32. Hopper, N. A., Anjard, C., Reymond, C. D., and Williams, J. G. (1993). Induction of terminal differentiation of Dictyostelium cAMP-dependent protein kinase and opposing effects of intracellular and extracellular cAMP on stalk cell differentiation. Development 119, 147-154.
33. Soede, R. D. M., Hopper, N. A., Williams, J. G., and Schaap, P. (1996). Extracellular cAMP depletion triggers stalk gene expression in Dictyostelium: Disparities in developmental timing and dose dependency indicate that prespore induction and stalk repression by cAMP are mediated by separate signaling pathways. Dev. Biol. 177, 152-159.
34. Schaap, P., Van Lookeren Campagne, M. M., Van Driel, R., Spek, W., Van Haastert, P. J. M., and Pinas, J. (1986). Postaggregative differentiation induction by cyclic AMP in Dictyostelium: Intracellular transduction pathway and requirement for additional stimuli. Dev. Biol. 118, 52-63.
35. ++ antagonists distinguish different requirements for cAMP-mediated gene expression in the cellular slime mold, Dictyostelium discoideum. Differentiation 41, 14-21.
36. 2+. Biochem. J. 313, 661-667.
37. Kobayashi, E., Nakano, H., Morimoto, M., and Tamaoki, T. (1989). Calphostin C (UCN-1028C), a novel microbial compound, is a highly potent and specific inhibitor of protein kinase C. Biochem. Biophys. Res. Commun. 159, 548-553.
38. Gordge, P. C., and Ryves, W. J. (1994). Inhibitors of protein kinase C. Cell. Signaling 6, 871-882.
39. Knetsch, M. L. W. (1996). "Function and Regulation of Protein Kinase C and MAP Kinase in Dictyostelium Signal Transduction," Ph.D. thesis, Leiden University, The Netherlands.
40. Castagna, M., Takai, Y., Kaibuchi, K., Sano, K., Kikkawa, U., and Nishizuka, Y. (1982). Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor- promoting phorbol esters. J. Biol. Chem. 257, 7847-7851.