Crystallization of bulk samples of partially amorphous spray-dried lactose

Pharmaceutical Development and Technology

Volumn 3, Issue 4, 1998, Pages 503-507

  Darcy, Patricia ^a   Buckton, Graham ^a  

^a UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

Amorphous; Bulk storage; Crystallization; Lactose; Microcalorimetry

Indexed keywords

LACTOSE; WATER;

ARTICLE; CRYSTALLIZATION; DESORPTION; HYDRATION; MICROCALORIMETRY; PRIORITY JOURNAL;

EID: 0031771237     PISSN: 10837450     EISSN: None     Source Type: Journal    
DOI: 10.3109/10837459809028632     Document Type: Article

References (5)

1. T. Sebhatu, M. Angberg, and C. Ahlneck, Assessment of the degree of disorder in crystalline solids by isothermal microcalorimetry, Int. J. Pharm., 104, 135-144, (1994).
2. L-E. Briggner, G. Buckton, K. Bystrom, and P. Darcy, The use of isothermal microcalorimetry in the study of changes in crystallinity induced during the processing of powders, Int. J. Pharm., 105, 125-135 (1994).
3. A. A. Elamin, T. Sebhatu, and C. Ahlneck, The use of amorphous model substances to study mechanically activated materials in the solid state, Int. J. Pharm., 119, 25-36 (1995).
4. G. Buckton and P. Darcy, The influence of additives on the recrystallisation of spray dried lactose, Int. J. Pharm., 121, 81-87 (1995).
5. G. Buckton and P. Darcy, Water mobility in amorphous lactose below and close to the glass transition temperature, Int. J. Pharm., 136, 141-146 (1996).