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Volumn 5, Issue 11, 1998, Pages 984-995

Correlation of genetic instability and apoptosis in the presence of oncogenic Ki-Ras

Author keywords

Apoptosis; CAD gene amplification; Clonogenicity; Genomic instability; p53; ras oncogene; Tumor suppressors

Indexed keywords

PROTEIN P53;

EID: 0031771114     PISSN: 13509047     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cdd.4400448     Document Type: Article
Times cited : (14)

References (87)
  • 2
    • 0025937489 scopus 로고
    • Constitutive c-myc expression in an IL-3-dependent myeloid cell line suppresses cell cycle arrest and accelerates apoptosis
    • Askew DS, Ashmun RA, Simmons BC, and Cleveland JL (1991) Constitutive c-myc expression in an IL-3-dependent myeloid cell line suppresses cell cycle arrest and accelerates apoptosis. Oncogene 6: 1915-1922
    • (1991) Oncogene , vol.6 , pp. 1915-1922
    • Askew, D.S.1    Ashmun, R.A.2    Simmons, B.C.3    Cleveland, J.L.4
  • 3
    • 0028175091 scopus 로고
    • Raf meets Ras. completing the framework of a signal transduction pathway
    • Avruch J, Zhang X and Kyriakis JM (1994) Raf meets Ras. completing the framework of a signal transduction pathway Trends in Biochem Sci. 19: 279-283
    • (1994) Trends in Biochem Sci. , vol.19 , pp. 279-283
    • Avruch, J.1    Zhang, X.2    Kyriakis, J.M.3
  • 4
    • 0021112720 scopus 로고
    • Accumulation of DNA strand breaks during thymineless death in thymidylate synthase-negative mutants of mouse FM3A cells J
    • Ayusawa D, Shimizu K, Koyama H, Takeishi K and Seno T (1983) Accumulation of DNA strand breaks during thymineless death in thymidylate synthase-negative mutants of mouse FM3A cells J. Biol. Chem. 258: 12448-12454
    • (1983) Biol. Chem. , vol.258 , pp. 12448-12454
    • Ayusawa, D.1    Shimizu, K.2    Koyama, H.3    Takeishi, K.4    Seno, T.5
  • 6
    • 0022137480 scopus 로고
    • Microinjection of the ras oncogene protein into PC12 cell induces morphological differentiation
    • Bar-Sagi D and Feramisco JR (1985) Microinjection of the ras oncogene protein into PC12 cell induces morphological differentiation. Cell 42: 841-848
    • (1985) Cell , vol.42 , pp. 841-848
    • Bar-Sagi, D.1    Feramisco, J.R.2
  • 7
    • 0029099361 scopus 로고
    • Spontaneous and ionizing radiation-induced chromosomal abnormalities in p53-deficient mice
    • Bouffler SD, Kemp CJ, Balman A and Cox K (1995) Spontaneous and ionizing radiation-induced chromosomal abnormalities in p53-deficient mice. Cancer Res. 55: 3883-3889
    • (1995) Cancer Res. , vol.55 , pp. 3883-3889
    • Bouffler, S.D.1    Kemp, C.J.2    Balman, A.3    Cox, K.4
  • 8
    • 0027465064 scopus 로고
    • Epidermal growth factor regulates the exchange rate of guanine nucleotides on p21 Ras in fibroblasts
    • Buday L and Downward J (1993) Epidermal growth factor regulates the exchange rate of guanine nucleotides on p21 Ras in fibroblasts. Mol. Cell. Biol. 13: 1903-1910
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 1903-1910
    • Buday, L.1    Downward, J.2
  • 9
    • 0025711758 scopus 로고
    • Ras proteins Some signal developments
    • Bourne HR, Wrischnik L and Kenyon C (1990) Ras proteins Some signal developments Nature 348: 678-679
    • (1990) Nature , vol.348 , pp. 678-679
    • Bourne, H.R.1    Wrischnik, L.2    Kenyon, C.3
  • 10
    • 0023339504 scopus 로고
    • Molecular analysis and chromosomal mapping of amplified genes isolated from a transformed mouse 3T3 cell line
    • Cahilly-Snyder L, Yang-Feng T, Fancke U and George DL (1987) Molecular analysis and chromosomal mapping of amplified genes isolated from a transformed mouse 3T3 cell line. Somat Cell Mol. Genet. 13: 235-244
    • (1987) Somat Cell Mol. Genet. , vol.13 , pp. 235-244
    • Cahilly-Snyder, L.1    Yang-Feng, T.2    Fancke, U.3    George, D.L.4
  • 12
    • 84920320019 scopus 로고
    • Relationship between cell survival and the incidence of micronuclei after low and high dose rate γ-irradiation of normal human fibroblasts
    • Chen C-Y and Geard CR (1990) Relationship between cell survival and the incidence of micronuclei after low and high dose rate γ-irradiation of normal human fibroblasts. Radiat. Res. 124: 125-132
    • (1990) Radiat. Res. , vol.124 , pp. 125-132
    • Chen, C.-Y.1    Geard, C.R.2
  • 13
    • 0028971751 scopus 로고
    • Direction of p21 Ras-generated signals cell growth or apoptosis is determined by protein kinase C and Bcl-2
    • Chen C-Y and Faller DV (1995) Direction of p21 Ras-generated signals cell growth or apoptosis is determined by protein kinase C and Bcl-2. Oncogene 11: 1487-1498
    • (1995) Oncogene , vol.11 , pp. 1487-1498
    • Chen, C.-Y.1    Faller, D.V.2
  • 14
    • 0030048476 scopus 로고    scopus 로고
    • Phosphorylation of Bcl-2 protein and association with p21Ras in Ras-induced apoptosis
    • Chen C-Y and Faller DV (1996) Phosphorylation of Bcl-2 protein and association with p21Ras in Ras-induced apoptosis. J. Biol. Chem. 271: 2376-2379
    • (1996) J. Biol. Chem. , vol.271 , pp. 2376-2379
    • Chen, C.-Y.1    Faller, D.V.2
  • 15
    • 0032479284 scopus 로고    scopus 로고
    • Differential regulation of discrete apoptotic pathways by Ras
    • in press
    • Chen C-Y, Liou J, Forman LW, and Faller DV (1998) Differential regulation of discrete apoptotic pathways by Ras. J. Biol. Chem., in press
    • (1998) J. Biol. Chem.
    • Chen, C.-Y.1    Liou, J.2    Forman, L.W.3    Faller, D.V.4
  • 16
    • 0026555717 scopus 로고
    • Modulation of activity of the promoter of the human MDRI gene by Ras and p53
    • Chin K-V, Ueda K, Pastan I and Gottesman MM (1992) Modulation of activity of the promoter of the human MDRI gene by Ras and p53 Science 255: 459-462
    • (1992) Science , vol.255 , pp. 459-462
    • Chin, K.-V.1    Ueda, K.2    Pastan, I.3    Gottesman, M.M.4
  • 17
    • 0028338927 scopus 로고
    • The human Ha-ras oncogene induces genomic instability in murine fibroblasts within one cell cycle
    • Denko NC, Giaccia AJ, Stnnger JR and Stambrook PJ (1994) The human Ha-ras oncogene induces genomic instability in murine fibroblasts within one cell cycle. Proc Natl. Acad. Sci. USA 91: 5124-5128
    • (1994) Proc Natl. Acad. Sci. USA , vol.91 , pp. 5124-5128
    • Denko, N.C.1    Giaccia, A.J.2    Stnnger, J.R.3    Stambrook, P.J.4
  • 18
    • 0027155140 scopus 로고
    • Transfected c-Ha-ras oncogene enhances karyotypic instability and integrates predominantly in aberrant chromosomes
    • de Vries JE, Komips FHAC, Marx P, Bosman FT, Geraedts JPM and Kate JT (1993) Transfected c-Ha-ras oncogene enhances karyotypic instability and integrates predominantly in aberrant chromosomes. Cancer Genet Gyotgenet. 65: 35-43
    • (1993) Cancer Genet Gyotgenet. , vol.65 , pp. 35-43
    • De Vries, J.E.1    Komips, F.H.A.C.2    Marx, P.3    Bosman, F.T.4    Jpm, G.5    Kate, J.T.6
  • 23
    • 0025853776 scopus 로고
    • Tumorigenic potential associated with enhanced expression of a gene that is amplified in a mouse tumor cell line
    • Fakharzadeh SS, Trusko SP and George DL (1991) Tumorigenic potential associated with enhanced expression of a gene that is amplified in a mouse tumor cell line. EMBO J. 10: 1565-1569
    • (1991) EMBO J. , vol.10 , pp. 1565-1569
    • Fakharzadeh, S.S.1    Trusko, S.P.2    George, D.L.3
  • 24
    • 0028170198 scopus 로고
    • v-mos suppresses platelet-denved growth factor (PDGF) type-beta receptor autophosphorylation and inhibits PDGF-BB-mediated signal transduction
    • Faller DV, Mundschau LJ, Forman LW and Quinones MA (1994) v-mos suppresses platelet-denved growth factor (PDGF) type-beta receptor autophosphorylation and inhibits PDGF-BB-mediated signal transduction. J. Biol. Chem. 269: 5022-5029.
    • (1994) J. Biol. Chem. , vol.269 , pp. 5022-5029
    • Faller, D.V.1    Mundschau, L.J.2    Forman, L.W.3    Quinones, M.A.4
  • 25
    • 0020793569 scopus 로고
    • A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity
    • Feinberg AP and Volgelstein B (1983) A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal. Biochem. 132: 6-13
    • (1983) Anal. Biochem. , vol.132 , pp. 6-13
    • Feinberg, A.P.1    Volgelstein, B.2
  • 27
    • 0024382760 scopus 로고
    • The p53 proto-oncogene can act as a suppressor of transformation
    • Finlay CA, Hinds PW and Levine AJ (1989) The p53 proto-oncogene can act as a suppressor of transformation. Cell 57: 1083-1093
    • (1989) Cell , vol.57 , pp. 1083-1093
    • Finlay, C.A.1    Hinds, P.W.2    Levine, A.J.3
  • 28
    • 0028025563 scopus 로고
    • Apoptosis in cancer therapy: Crossing the threshold
    • Fisher DE (1994) Apoptosis in cancer therapy: crossing the threshold Cell 78: 539-542
    • (1994) Cell , vol.78 , pp. 539-542
    • Fisher, D.E.1
  • 32
  • 33
    • 0027935756 scopus 로고
    • Interaction of Ras and Raf in intact mammalian cells upon extracellular stimulation
    • Hallberg B, Rayter SI and Downward J (1994) Interaction of Ras and Raf in intact mammalian cells upon extracellular stimulation. J Biol. Chem. 269: 3913-3916
    • (1994) J Biol. Chem. , vol.269 , pp. 3913-3916
    • Hallberg, B.1    Rayter, S.I.2    Downward, J.3
  • 34
    • 0028263811 scopus 로고
    • c-myc-induced apoptosis in fibroblasts is inhibited by specific cytokines
    • Harnngton EA, Bennett MR, Fanidi A and Evan GI (1994) c-myc-induced apoptosis in fibroblasts is inhibited by specific cytokines EMBO J. 13: 3286-3295
    • (1994) EMBO J. , vol.13 , pp. 3286-3295
    • Harnngton, E.A.1    Bennett, M.R.2    Fanidi, A.3    Evan, G.I.4
  • 35
    • 0027489384 scopus 로고
    • Clinical implication of the p53 tumor suppressor gene
    • Harris CC and Hellstein M (1993) Clinical implication of the p53 tumor suppressor gene. N. Engl. J. Med. 329: 1318-1327
    • (1993) N. Engl. J. Med. , vol.329 , pp. 1318-1327
    • Harris, C.C.1    Hellstein, M.2
  • 36
    • 0024425887 scopus 로고
    • Checkpoints: Controls that ensure the order of cell cycle events
    • Hartwell LH and Weinert TA (1989) Checkpoints: controls that ensure the order of cell cycle events Science 246: 629-634
    • (1989) Science , vol.246 , pp. 629-634
    • Hartwell, L.H.1    Weinert, T.A.2
  • 37
    • 0026452949 scopus 로고
    • Defects in a cell cycle checkpoint may be responsible for the genomic instability of cancer cells
    • Hartwell LH (1992) Defects in a cell cycle checkpoint may be responsible for the genomic instability of cancer cells. Cell 71: 543-546
    • (1992) Cell , vol.71 , pp. 543-546
    • Hartwell, L.H.1
  • 38
    • 0028568315 scopus 로고
    • Cell cycle control and cancer
    • Hartwell LH and Kastan MB (1994) Cell cycle control and cancer. Science 266: 1821-1828
    • (1994) Science , vol.266 , pp. 1821-1828
    • Hartwell, L.H.1    Kastan, M.B.2
  • 39
    • 0026656213 scopus 로고
    • Activation of mitogen-activated protein kinase and its activator by ras in intact cells and in a cell-free system
    • Hattori S, Fukuda M, Yamashita T, Nakamura S, Gotoh Y and Hishida E (1992) Activation of mitogen-activated protein kinase and its activator by ras in intact cells and in a cell-free system J. Biol. Chem. 267: 20436-20351
    • (1992) J. Biol. Chem. , vol.267 , pp. 20436-120351
    • Hattori, S.1    Fukuda, M.2    Yamashita, T.3    Nakamura, S.4    Gotoh, Y.5    Hishida, E.6
  • 40
    • 0025969355 scopus 로고
    • Mutant p53 tumor suppressor alleles release ras-induced cell cycle growth arrest
    • Hick GG, Egan SE, Greenberg AH and Mowat M (1991) Mutant p53 tumor suppressor alleles release ras-induced cell cycle growth arrest. Mole. Cell. Biol. 11: 1344-1352
    • (1991) Mole. Cell. Biol. , vol.11 , pp. 1344-1352
    • Hick, G.G.1    Egan, S.E.2    Greenberg, A.H.3    Mowat, M.4
  • 41
    • 0040433650 scopus 로고
    • Rescue of cells from ras oncogene-induced growth arrest by a second, complementing, oncogene
    • Hirakawa T and Ruley HE (1988) Rescue of cells from ras oncogene-induced growth arrest by a second, complementing, oncogene. Proc. Natl. Acad. Sci USA 85: 1519-1523
    • (1988) Proc. Natl. Acad. Sci USA , vol.85 , pp. 1519-1523
    • Hirakawa, T.1    Ruley, H.E.2
  • 44
    • 0029065719 scopus 로고
    • Identification of an origin of bidirectional DNA replication in the ubiquitously expressed mammalian CAD gene
    • Kelly RE, DeRose ML, Draper BW and Wahl GM (1995) Identification of an origin of bidirectional DNA replication in the ubiquitously expressed mammalian CAD gene. Mol. Cell. Biol. 15: 4136-4148
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 4136-4148
    • Kelly, R.E.1    DeRose, M.L.2    Draper, B.W.3    Wahl, G.M.4
  • 46
    • 0020376813 scopus 로고
    • Thymineless death and mutation induction in cultured mouse FM3A cell mutants deficient in thymidylate synthase
    • Koyama H, Ayusawa D, Tsuji M and Seno T (1982) Thymineless death and mutation induction in cultured mouse FM3A cell mutants deficient in thymidylate synthase. Mutat. Res. 105: 433-438
    • (1982) Mutat. Res. , vol.105 , pp. 433-438
    • Koyama, H.1    Ayusawa, D.2    Tsuji, M.3    Seno, T.4
  • 47
    • 0028033027 scopus 로고
    • Susceptibility to radiation-carcinogenesis and accumulation of chromosomal breakage in p53 deficient mice
    • Lee JM, Abrahamson JL, Kandel R, Donehower LA and Bernstein A (1994) Susceptibility to radiation-carcinogenesis and accumulation of chromosomal breakage in p53 deficient mice Oncogene 9: 3731-3736
    • (1994) Oncogene , vol.9 , pp. 3731-3736
    • Lee, J.M.1    Abrahamson, J.L.2    Kandel, R.3    Donehower, L.A.4    Bernstein, A.5
  • 48
    • 0026774181 scopus 로고
    • Nerve growth factor stimulation of the Ras-guanine nucleotide exchange factor and GAP activities
    • Li B-Q, Kaplan D, Kung H-F and Kamata T (1992) Nerve growth factor stimulation of the Ras-guanine nucleotide exchange factor and GAP activities. Science 256: 1456-1459
    • (1992) Science , vol.256 , pp. 1456-1459
    • Li, B.-Q.1    Kaplan, D.2    Kung, H.-F.3    Kamata, T.4
  • 49
    • 0029017456 scopus 로고
    • Ras transformation results in an elevated level of cyclin D1 and acceleration of G1 progression in NIH-3T3 cells
    • Liu J-J, Chao J-R, Jiang M-C, Ng S-Y, Yen JJ and Yen HEY (1995) Ras transformation results in an elevated level of cyclin D1 and acceleration of G1 progression in NIH-3T3 cells Mol. Cell. Biol 15: 3654-3663
    • (1995) Mol. Cell. Biol , vol.15 , pp. 3654-3663
    • Liu, J.-J.1    Chao, J.-R.2    Jiang, M.-C.3    Ng, S.-Y.4    Yen, J.J.5    Hey, Y.6
  • 50
    • 0026801062 scopus 로고
    • Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53
    • Livingstone LR, White A, Sprouse J, Livanos E, Jacks T and Tlsty TD (1992) Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53. Cell 70: 923-935
    • (1992) Cell , vol.70 , pp. 923-935
    • Livingstone, L.R.1    White, A.2    Sprouse, J.3    Livanos, E.4    Jacks, T.5    Tlsty, T.D.6
  • 51
    • 0027976222 scopus 로고
    • Oncogenic activity of cyclin D1 revealed through cooperation with Ha-ras: Link between cell cycle control and malignant transformation
    • Lovec H, Sewing A, Lucibello FC, Muller R and Moroy T (1994) Oncogenic activity of cyclin D1 revealed through cooperation with Ha-ras: link between cell cycle control and malignant transformation. Oncogene 9: 323-326
    • (1994) Oncogene , vol.9 , pp. 323-326
    • Lovec, H.1    Sewing, A.2    Lucibello, F.C.3    Muller, R.4    Moroy, T.5
  • 52
    • 0026636158 scopus 로고
    • Ras-induced hyperplasia occurs with mutation of p53, but activated ras and myc together can induce carcinoma without p53 mutation
    • Lu X, Park SH, Thompson TC and Lane P (1992) Ras-induced hyperplasia occurs with mutation of p53, but activated ras and myc together can induce carcinoma without p53 mutation. Cell 70: 153-161
    • (1992) Cell , vol.70 , pp. 153-161
    • Lu, X.1    Park, S.H.2    Thompson, T.C.3    Lane, P.4
  • 53
    • 0027335964 scopus 로고
    • The effector interactions of p21 Ras
    • Marshall MS (1993) The effector interactions of p21 Ras. Trends Biochem. Sci 18: 250-254
    • (1993) Trends Biochem. Sci , vol.18 , pp. 250-254
    • Marshall, M.S.1
  • 54
    • 0028605343 scopus 로고
    • New link found between p53 and DNA repair
    • Marx J (1994) New link found between p53 and DNA repair. Science 266: 1321-1322
    • (1994) Science , vol.266 , pp. 1321-1322
    • Marx, J.1
  • 55
    • 0028137615 scopus 로고
    • Activators and effectors of ras p21 proteins
    • McCormick F (1994) Activators and effectors of ras p21 proteins. Curr. Opin Genet. Dev 4: 82-96
    • (1994) Curr. Opin Genet. Dev , vol.4 , pp. 82-96
    • McCormick, F.1
  • 56
    • 0030052074 scopus 로고    scopus 로고
    • Regulation of radiation-induced apoptosis in oncogene-transfected fibroblasts. influence of Ha-ras on the G2 delay
    • McKenna WG, Bernhard EJ, Markiewicz DA, Rudoltz MS, Maity A and Muschel RJ (1996) Regulation of radiation-induced apoptosis in oncogene-transfected fibroblasts. influence of Ha-ras on the G2 delay. Oncogene 12: 237-245
    • (1996) Oncogene , vol.12 , pp. 237-245
    • McKenna, W.G.1    Bernhard, E.J.2    Markiewicz, D.A.3    Rudoltz, M.S.4    Maity, A.5    Muschel, R.J.6
  • 60
    • 0027337519 scopus 로고
    • Complexes of Ras-GTP with Raf-1 and mitogen-activated protein kinase
    • Moodie SA, Willumsen BM, Weber MJ and Wolfman A (1993) Complexes of Ras-GTP with Raf-1 and mitogen-activated protein kinase. Science 260: 1658-1661
    • (1993) Science , vol.260 , pp. 1658-1661
    • Moodie, S.A.1    Willumsen, B.M.2    Weber, M.J.3    Wolfman, A.4
  • 61
    • 0020443654 scopus 로고
    • Kintics of N-(phosphonacetyl)-L-aspartate and pyrazofurin depletion of pynmidine ribonucleotide and deoxyribonucleotide pools and their relationship to nucleic acid synthesis in intact and permeabilized cells
    • Moyer JD, Smith PA, Levy EJ and Handschumacher RE (1982) Kintics of N-(phosphonacetyl)-L-aspartate and pyrazofurin depletion of pynmidine ribonucleotide and deoxyribonucleotide pools and their relationship to nucleic acid synthesis in intact and permeabilized cells. Cancer Res. 42: 4525-4531
    • (1982) Cancer Res. , vol.42 , pp. 4525-4531
    • Moyer, J.D.1    Smith, P.A.2    Levy, E.J.3    Handschumacher, R.E.4
  • 62
    • 0024292712 scopus 로고
    • The human papillomavirus type 16E7 gene encodes transactivation and transformation functions similar to those of adenovirus E1A
    • Phelps WC, Yee CC, Munger K and Howley PM (1989) The human papillomavirus type 16E7 gene encodes transactivation and transformation functions similar to those of adenovirus E1A Cell 53: 539-547
    • (1989) Cell , vol.53 , pp. 539-547
    • Phelps, W.C.1    Yee, C.C.2    Munger, K.3    Howley, P.M.4
  • 63
    • 0027583889 scopus 로고
    • Doing the right things, feedback control and p53
    • Prives C (1993) Doing the right things, feedback control and p53. Curr. Opinion in Cell Biology 5: 214-218
    • (1993) Curr. Opinion in Cell Biology , vol.5 , pp. 214-218
    • Prives, C.1
  • 64
    • 0028025564 scopus 로고
    • How loops, βsheets, and α helices help us to understand p53
    • Prives C (1994) How loops, βsheets, and α helices help us to understand p53. Cell 78: 543-546
    • (1994) Cell , vol.78 , pp. 543-546
    • Prives, C.1
  • 65
    • 0024026804 scopus 로고
    • Ras-mediated cell cycle arrest is altered by nuclear oncogenes to induce Schwann cell transformation
    • Ridley AJ, Paterson HF, Noble M and Lane H (1988) Ras-mediated cell cycle arrest is altered by nuclear oncogenes to induce Schwann cell transformation. EMBO J 7: 1635-1645
    • (1988) EMBO J , vol.7 , pp. 1635-1645
    • Ridley, A.J.1    Paterson, H.F.2    Noble, M.3    Lane, H.4
  • 66
    • 0027365944 scopus 로고
    • Multiple mechanisms of N-(phosphonoacetyl)-L-aspartate drug resistance in SV40-infected precrisis human fibroblasts
    • Schaefer DI, Livanos EM, White AE and Tlsty TD (1993) Multiple mechanisms of N-(phosphonoacetyl)-L-aspartate drug resistance in SV40-infected precrisis human fibroblasts. Cancer Res 53: 4946-4951
    • (1993) Cancer Res , vol.53 , pp. 4946-4951
    • Schaefer, D.I.1    Livanos, E.M.2    White, A.E.3    Tlsty, T.D.4
  • 69
    • 0030944985 scopus 로고    scopus 로고
    • Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a
    • Serrano M, Lin AW, McCurrach ME, Beach D and Lowe SW (1997) Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a. Cell 88: 593-602
    • (1997) Cell , vol.88 , pp. 593-602
    • Serrano, M.1    Lin, A.W.2    McCurrach, M.E.3    Beach, D.4    Lowe, S.W.5
  • 70
    • 0028988585 scopus 로고
    • Inhibitors of mammalian G1 cyclin-dependent kinases
    • Sherr CJ and Roberts JM (1995) Inhibitors of mammalian G1 cyclin-dependent kinases Gene & Devel. 9: 1149-1163
    • (1995) Gene & Devel. , vol.9 , pp. 1149-1163
    • Sherr, C.J.1    Roberts, J.M.2
  • 73
    • 0027218485 scopus 로고
    • Regulation and mechanisms of mammalian gene amplification
    • Stark GR (1993) Regulation and mechanisms of mammalian gene amplification. Genetics in Cancer Res. 61: 87-113
    • (1993) Genetics in Cancer Res. , vol.61 , pp. 87-113
    • Stark, G.R.1
  • 74
    • 0024022067 scopus 로고
    • Comparison of the in vitro transforming activities of human papillomavirus types
    • Storey A, Pim D, Murray A, Osborn K, Banks L and Crawford L (1988) Comparison of the in vitro transforming activities of human papillomavirus types. EMBO J. 7: 1815-1820
    • (1988) EMBO J. , vol.7 , pp. 1815-1820
    • Storey, A.1    Pim, D.2    Murray, A.3    Osborn, K.4    Banks, L.5    Crawford, L.6
  • 76
    • 0024357990 scopus 로고
    • Differences in the rates of gene amplification in nontumorigenic and tumorigenic cell lines as measured by Luria-Delbruck fluctuation analysis
    • Tlsty TD, Margolin BH and Lum K (1989) Differences in the rates of gene amplification in nontumorigenic and tumorigenic cell lines as measured by Luria-Delbruck fluctuation analysis. Proc. Natl Acad. Sci USA 86: 9441-9445
    • (1989) Proc. Natl Acad. Sci USA , vol.86 , pp. 9441-9445
    • Tlsty, T.D.1    Margolin, B.H.2    Lum, K.3
  • 77
    • 0025253116 scopus 로고
    • Normal diploid human and rodent cells lack a detectable frequency of gene amplification
    • Tlsty TD (1990) Normal diploid human and rodent cells lack a detectable frequency of gene amplification. Proc. Natl. Acad Sci. USA 87: 3132-3136
    • (1990) Proc. Natl. Acad Sci. USA , vol.87 , pp. 3132-3136
    • Tlsty, T.D.1
  • 78
    • 0026669469 scopus 로고
    • p53 function and dysfunction
    • Vogelstein B and Kinzler KW (1992) p53 function and dysfunction. Cell 70: 523-526
    • (1992) Cell , vol.70 , pp. 523-526
    • Vogelstein, B.1    Kinzler, K.W.2
  • 79
    • 0027250250 scopus 로고
    • Mammalian Ras interacts directly with the serine/threonine kinase Raf
    • Vojtek AB, Hollenberg SM and Cooper JA (1993) Mammalian Ras interacts directly with the serine/threonine kinase Raf. Cell 74: 205-214
    • (1993) Cell , vol.74 , pp. 205-214
    • Vojtek, A.B.1    Hollenberg, S.M.2    Cooper, J.A.3
  • 80
    • 0021320685 scopus 로고
    • Mutagenesis and inducible responses to DNA damage in E. coli
    • Walker GC (1984) Mutagenesis and inducible responses to DNA damage in E. coli. Microbiol Rev. 48: 60-93
    • (1984) Microbiol Rev. , vol.48 , pp. 60-93
    • Walker, G.C.1
  • 82
    • 0029033861 scopus 로고
    • The retinoblastoma protein and cell cycle control
    • Weinberg RA (1995) The retinoblastoma protein and cell cycle control. Cell 81: 323-330
    • (1995) Cell , vol.81 , pp. 323-330
    • Weinberg, R.A.1
  • 83
    • 0026018901 scopus 로고
    • A central role for chromosome breakage in gene amplification, deletion formation, and amplicon integration
    • Windle B, Draper BW, Yin X, O'Gorman S and Wahl GM (1991) A central role for chromosome breakage in gene amplification, deletion formation, and amplicon integration. Gene. Dev. 5: 160-174
    • (1991) Gene. Dev. , vol.5 , pp. 160-174
    • Windle, B.1    Draper, B.W.2    Yin, X.3    O'Gorman, S.4    Wahl, G.M.5
  • 84
  • 85
    • 0026801977 scopus 로고
    • Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles
    • Yin Y, Tainsky MA, Bischoff FZ, Strong LC and Wahl GM (1992) Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles Cell 70: 937-948
    • (1992) Cell , vol.70 , pp. 937-948
    • Yin, Y.1    Tainsky, M.A.2    Bischoff, F.Z.3    Strong, L.C.4    Wahl, G.M.5
  • 86
    • 0026657399 scopus 로고
    • Mechanistic aspects of signaling through Ras in NIH3T3 cells
    • Zhang K, Papageorge AG and Lowy DR (1992) Mechanistic aspects of signaling through Ras in NIH3T3 cells. Science 257: 671-674
    • (1992) Science , vol.257 , pp. 671-674
    • Zhang, K.1    Papageorge, A.G.2    Lowy, D.R.3
  • 87
    • 0023761661 scopus 로고
    • p21 v-ras inhibits induction of c-myc and c-fos expression by platelet-derived growth factor
    • Zullo JN and Faller DV (1988) p21 v-ras inhibits induction of c-myc and c-fos expression by platelet-derived growth factor. Mol. Cell. Biol 8: 5080-5085
    • (1988) Mol. Cell. Biol , vol.8 , pp. 5080-5085
    • Zullo, J.N.1    Faller, D.V.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.